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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of telomere maintenance
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Accession:GO:0032204 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.


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regulation of telomere maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac8 histone deacetylase 8 involved_in ISO
IEA		 (PMID:16809764)
GO_REF:0000107		 RGD
Ensembl		 PMID:16809764 GO_REF:0000107 NCBI chr  X:67,385,288...67,593,014
Ensembl chr  X:67,385,289...67,592,923 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D involved_in ISO (MGI:5438900|PMID:22633954) RGD PMID:22633954 MGI:5438900 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786 		JBrowse link
G Lmna lamin A/C involved_in ISO (PMID:25399868) RGD PMID:25399868 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO
ISS		 (PMID:17765874)
GO_REF:0000024		 RGD
UniProt		 PMID:17765874 GO_REF:0000024 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Smg1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase involved_in ISO (PMID:17916692) RGD PMID:17916692 NCBI chr 1:172,441,892...172,543,667
Ensembl chr 1:172,444,936...172,543,698 		JBrowse link
G Smg5 SMG5 nonsense mediated mRNA decay factor involved_in ISO (PMID:16809764) RGD PMID:16809764 NCBI chr 2:173,804,987...173,832,102
Ensembl chr 2:173,805,019...173,832,102 		JBrowse link
G Smg6 SMG6 nonsense mediated mRNA decay factor involved_in ISO (PMID:12699629), (PMID:17916692) RGD PMID:12699629 PMID:17916692 NCBI chr10:59,786,258...60,014,395
Ensembl chr10:59,786,258...60,014,395 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:22536324) RGD PMID:22536324 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Upf1 UPF1, RNA helicase and ATPase involved_in ISO (PMID:17916692) RGD PMID:17916692 NCBI chr16:19,076,594...19,097,365
Ensembl chr16:19,076,322...19,096,568 		JBrowse link
G Ylpm1 YLP motif containing 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:15100092)		 GO_Central
RGD		 PMID:15100092 GO_REF:0000033 NCBI chr 6:104,642,615...104,718,508
Ensembl chr 6:104,642,615...104,718,508 		JBrowse link
negative regulation of protection from non-homologous end joining at telomere term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (PMID:14690602) RGD PMID:14690602 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:14690602) RGD PMID:14690602 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 involved_in ISO (MGI:3758502|PMID:14690602)
(PMID:14690602)		 RGD PMID:14690602 MGI:3758502 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 involved_in ISO (MGI:3758502|PMID:14690602)
(PMID:14690602)		 RGD PMID:14690602 MGI:3758502 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808 		JBrowse link
negative regulation of t-circle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO
IBA		 (PMID:25620558)
GO_REF:0000033
(MGI:5522574|PMID:24115439), (MGI:5645200|PMID:22579284)		 RGD
GO_Central		 PMID:22579284 PMID:24115439 PMID:25620558 GO_REF:0000033 MGI:5522574 MGI:5645200 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:15507207) RGD PMID:15507207 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:19581589) RGD PMID:19581589 NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
negative regulation of telomere capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO (PMID:17694070) RGD PMID:17694070 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Nbn nibrin involved_in IEA
ISO		 GO_REF:0000107
(PMID:17694070)		 Ensembl
RGD		 PMID:17694070 GO_REF:0000107 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in ISO
IEA		 (PMID:17694070)
GO_REF:0000107		 RGD
Ensembl		 PMID:17694070 GO_REF:0000107 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Smg6 SMG6 nonsense mediated mRNA decay factor involved_in ISO (PMID:12676087) RGD PMID:12676087 NCBI chr10:59,786,258...60,014,395
Ensembl chr10:59,786,258...60,014,395 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:24270157) RGD PMID:24270157 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
negative regulation of telomere maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (PMID:17055345) RGD PMID:17055345 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:17055345) RGD PMID:17055345 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:11971978) RGD PMID:11971978 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Terf2ip TERF2 interacting protein involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr19:39,976,965...39,984,055
Ensembl chr19:39,976,906...39,984,064 		JBrowse link
G Tinf2 TERF1 interacting nuclear factor 2 acts_upstream_of_or_within ISO (PMID:12676566) RGD PMID:12676566 NCBI chr15:29,170,663...29,178,015
Ensembl chr15:29,170,652...29,176,984 		JBrowse link
negative regulation of telomere maintenance in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5645200|PMID:22579284)
(PMID:22579284)		 RGD PMID:22579284 MGI:5645200 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
negative regulation of telomere maintenance via recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IBA		 (PMID:15507207)
(PMID:24120135)
GO_REF:0000033
(MGI:5883205|PMID:24120135)		 RGD
GO_Central		 PMID:15507207 PMID:24120135 GO_REF:0000033 MGI:5883205 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in IEA
ISO
IBA		 GO_REF:0000107
UniProtKB:Q9NUX5 (PMID:15181449), (PMID:15380063), (PMID:25172512)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:15181449 PMID:15380063 PMID:25172512 GO_REF:0000033 GO_REF:0000107 NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461 		JBrowse link
G Ctc1 CST telomere replication complex component 1 involved_in ISO (PMID:22763445) RGD PMID:22763445 NCBI chr10:53,714,614...53,735,298
Ensembl chr10:53,714,644...53,735,298 		JBrowse link
G Dcp2 decapping mRNA 2 involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr18:36,750,732...36,787,067
Ensembl chr18:36,750,732...36,788,557 		JBrowse link
G Exosc10 exosome component 10 involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr 5:158,995,313...159,018,940
Ensembl chr 5:158,995,313...159,018,940 		JBrowse link
G Gnl3l G protein nucleolar 3 like involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr  X:19,961,277...19,994,454
Ensembl chr  X:19,958,603...19,994,508 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) RGD PMID:23935072 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609 		JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr15:24,779,593...24,809,213
Ensembl chr15:24,779,450...24,809,183 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in IEA
ISO		 GO_REF:0000107
(PMID:18082603)		 Ensembl
RGD		 PMID:18082603 GO_REF:0000107 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588 		JBrowse link
G Nat10 N-acetyltransferase 10 involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr 3:90,111,643...90,149,891
Ensembl chr 3:90,111,645...90,149,927 		JBrowse link
G Pif1 PIF1 5'-to-3' DNA helicase involved_in ISO (PMID:16522649), (PMID:23657261) RGD PMID:16522649 PMID:23657261 NCBI chr 8:66,110,641...66,120,202
Ensembl chr 8:66,111,072...66,120,200 		JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 involved_in ISO
IEA		 (PMID:11701125), (PMID:21119197)
GO_REF:0000107		 RGD
Ensembl		 PMID:11701125 PMID:21119197 GO_REF:0000107 NCBI chr15:38,097,896...38,157,143
Ensembl chr15:38,097,886...38,157,140 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:19567472) RGD PMID:19567472 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO UniProtKB:Q96AP0 (PMID:15181449), (PMID:15632080) RGD PMID:15181449 PMID:15632080 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Stn1 STN1 subunit of CST complex involved_in ISO
IEA		 (PMID:22763445)
GO_REF:0000107		 RGD
Ensembl		 PMID:22763445 GO_REF:0000107 NCBI chr 1:246,391,311...246,429,844
Ensembl chr 1:246,395,613...246,429,531 		JBrowse link
G Ten1 TEN1 subunit of CST complex involved_in ISO
IBA		 (PMID:22763445)
GO_REF:0000033		 RGD
GO_Central		 PMID:22763445 GO_REF:0000033 NCBI chr10:101,431,328...101,455,105
Ensembl chr10:101,431,328...101,453,052 		JBrowse link
G Tent4b terminal nucleotidyltransferase 4B involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr19:18,807,616...18,868,969
Ensembl chr19:18,807,525...18,869,537 		JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO UniProtKB:O14746 (PMID:11971978) RGD PMID:11971978 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:17055345) RGD PMID:17055345 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Tinf2 TERF1 interacting nuclear factor 2 involved_in ISO (PMID:10581025), (PMID:15133513) RGD PMID:10581025 PMID:15133513 NCBI chr15:29,170,663...29,178,015
Ensembl chr15:29,170,652...29,176,984 		JBrowse link
G Tp53 tumor protein p53 involved_in IEA
ISO		 GO_REF:0000107
(PMID:10597287)		 Ensembl
RGD		 PMID:10597287 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
negative regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:18812185) RGD PMID:18812185 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Mcrs1 microspherule protein 1 involved_in ISO (PMID:15044100) RGD PMID:15044100 NCBI chr 7:130,383,853...130,392,667
Ensembl chr 7:130,383,853...130,392,685 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO (MGI:5705431|PMID:26586427) RGD PMID:26586427 MGI:5705431 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (PMID:24012755) RGD PMID:24012755 NCBI chr 1:181,286,190...181,291,739
Ensembl chr 1:181,283,921...181,291,775 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (PMID:24012755) RGD PMID:24012755 NCBI chr10:11,526,623...11,549,313
Ensembl chr10:11,528,424...11,549,295 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:24012755) RGD PMID:24012755 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Tnks tankyrase involved_in ISO (PMID:25939383) RGD PMID:25939383 NCBI chr16:57,223,174...57,370,740
Ensembl chr16:57,225,094...57,366,260 		JBrowse link
G Tnks2 tankyrase 2 involved_in ISO (PMID:25939383) RGD PMID:25939383 NCBI chr 1:234,567,888...234,621,079
Ensembl chr 1:234,567,858...234,621,079 		JBrowse link
negative regulation of telomeric D-loop disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Terf1 telomeric repeat binding factor 1 involved_in ISO
IBA		 (PMID:15200954)
GO_REF:0000033		 RGD
GO_Central		 PMID:15200954 GO_REF:0000033 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IBA		 (PMID:15200954)
GO_REF:0000033		 RGD
GO_Central		 PMID:15200954 GO_REF:0000033 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
positive regulation of t-circle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (MGI:5645200|PMID:22579284)
(PMID:22579284)		 RGD PMID:22579284 MGI:5645200 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (MGI:5645200|PMID:22579284)
(PMID:22579284)		 RGD PMID:22579284 MGI:5645200 NCBI chr 1:181,286,190...181,291,739
Ensembl chr 1:181,283,921...181,291,775 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (MGI:5645200|PMID:22579284)
(PMID:22579284)		 RGD PMID:22579284 MGI:5645200 NCBI chr10:11,526,623...11,549,313
Ensembl chr10:11,528,424...11,549,295 		JBrowse link
positive regulation of telomere capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnrnpd heterogeneous nuclear ribonucleoprotein D involved_in
acts_upstream_of		 ISO (MGI:5438900|PMID:22633954)
(PMID:22633954)		 RGD PMID:22633954 MGI:5438900 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786 		JBrowse link
G Nabp2 nucleic acid binding protein 2 involved_in ISO
IEA		 (PMID:25589350)
GO_REF:0000107
(MGI:5629774|PMID:25589350)		 RGD
Ensembl		 PMID:25589350 GO_REF:0000107 MGI:5629774 NCBI chr 7:830,949...836,551
Ensembl chr 7:830,949...838,027 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (PMID:23959892) RGD PMID:23959892 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
G Tnks tankyrase involved_in IBA
ISO		 GO_REF:0000033
(PMID:25939383)		 GO_Central
RGD		 PMID:25939383 GO_REF:0000033 NCBI chr16:57,223,174...57,370,740
Ensembl chr16:57,225,094...57,366,260 		JBrowse link
G Tnks2 tankyrase 2 involved_in IBA
ISO		 GO_REF:0000033
(PMID:25939383)		 GO_Central
RGD		 PMID:25939383 GO_REF:0000033 NCBI chr 1:234,567,888...234,621,079
Ensembl chr 1:234,567,858...234,621,079 		JBrowse link
positive regulation of telomere maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler involved_in ISO
IEA
ISS		 (MGI:4454526|PMID:20110566)
(PMID:20110566)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20110566 GO_REF:0000024 GO_REF:0000107 MGI:4454526 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Aurkb aurora kinase B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21531765)		 Ensembl
RGD		 PMID:21531765 GO_REF:0000107 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO (PMID:22238380) RGD PMID:22238380 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572 		JBrowse link
G Gnl3 G protein nucleolar 3 involved_in ISO (PMID:22641345) RGD PMID:22641345 NCBI chr16:6,207,402...6,213,491
Ensembl chr16:6,207,402...6,213,392 		JBrowse link
G Klf4 KLF transcription factor 4 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(PMID:20629177)		 Ensembl
RGD		 PMID:20629177 GO_REF:0000107 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21531765)		 Ensembl
RGD		 PMID:21531765 GO_REF:0000107 NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 acts_upstream_of_or_within ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:48,431,801...48,519,358
Ensembl chr 1:48,431,830...48,519,358 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21531765)		 Ensembl
RGD		 PMID:21531765 GO_REF:0000107 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk15 mitogen-activated protein kinase 15 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(PMID:21531765)		 Ensembl
RGD		 PMID:21531765 GO_REF:0000107 NCBI chr 7:107,694,907...107,714,640
Ensembl chr 7:107,694,964...107,714,645 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 acts_upstream_of_or_within ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 acts_upstream_of ISO (PMID:21531765) RGD PMID:21531765 NCBI chr12:34,993,520...35,013,059
Ensembl chr12:34,994,092...35,013,052 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease involved_in ISO
IEA		 (PMID:16374507)
GO_REF:0000107		 RGD
Ensembl		 PMID:16374507 GO_REF:0000107 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:9637678) BHF-UCL PMID:9637678 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nbn nibrin involved_in IEA
ISO		 GO_REF:0000107
(PMID:16374507)		 Ensembl
RGD		 PMID:16374507 GO_REF:0000107 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Nek2 NIMA-related kinase 2 acts_upstream_of_or_within ISO (PMID:21531765) RGD PMID:21531765 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051 		JBrowse link
G Nek7 NIMA-related kinase 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21531765)		 Ensembl
RGD		 PMID:21531765 GO_REF:0000107 NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296 		JBrowse link
G Nvl nuclear VCP-like involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(PMID:22226966)		 Ensembl
RGD		 PMID:22226966 GO_REF:0000107 NCBI chr13:92,851,023...92,906,749
Ensembl chr13:92,853,650...92,906,049 		JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(PMID:21531765)		 Ensembl
RGD		 PMID:21531765 GO_REF:0000107 NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:26119943)
(PMID:22641345)		 RGD PMID:22641345 PMID:26119943 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase acts_upstream_of_or_within ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:95,341,465...95,346,921
Ensembl chr 1:95,341,620...95,346,920 		JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 involved_in ISO (PMID:23426265) RGD PMID:23426265 NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611 		JBrowse link
G Prkcq protein kinase C, theta involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21531765)		 Ensembl
RGD		 PMID:21531765 GO_REF:0000107 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704 		JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in ISO
IEA		 (PMID:16374507)
GO_REF:0000107		 RGD
Ensembl		 PMID:16374507 GO_REF:0000107 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5645200|PMID:22579284) RGD PMID:22579284 MGI:5645200 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:23201774), (PMID:25819580) RGD PMID:23201774 PMID:25819580 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (PMID:24012755) RGD PMID:24012755 NCBI chr10:11,526,623...11,549,313
Ensembl chr10:11,528,424...11,549,295 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:24012755)
MGI:3619525 (PMID:15968270)		 RGD PMID:15968270 PMID:24012755 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
positive regulation of telomere maintenance in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actl6a actin-like 6A involved_in ISO (MGI:5638510|PMID:23979016)
(PMID:23979016)		 RGD PMID:23979016 MGI:5638510 NCBI chr 2:115,492,374...115,508,401
Ensembl chr 2:115,492,285...115,508,401 		JBrowse link
G Actr5 actin related protein 5 involved_in ISO (MGI:5638510|PMID:23979016)
(PMID:23979016)		 RGD PMID:23979016 MGI:5638510 NCBI chr 3:147,282,461...147,295,870
Ensembl chr 3:147,282,624...147,296,110 		JBrowse link
G Actr8 actin related protein 8 involved_in ISO (MGI:5638510|PMID:23979016)
(PMID:23979016)		 RGD PMID:23979016 MGI:5638510 NCBI chr16:5,164,131...5,186,353
Ensembl chr16:5,164,129...5,178,577 		JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO (MGI:5638510|PMID:23979016)
(PMID:23979016)		 RGD PMID:23979016 MGI:5638510 NCBI chr 3:106,368,455...106,465,716
Ensembl chr 3:106,368,455...106,467,911 		JBrowse link
G Ino80b INO80 complex subunit B involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 4:115,627,907...115,631,069
Ensembl chr 4:115,627,908...115,631,456 		JBrowse link
G Ino80c INO80 complex subunit C involved_in ISO (MGI:5638510|PMID:23979016)
(PMID:23979016)		 RGD PMID:23979016 MGI:5638510 NCBI chr18:15,378,764...15,398,574
Ensembl chr18:15,378,770...15,393,403 		JBrowse link
G Ino80d INO80 complex subunit D involved_in ISO (MGI:5638510|PMID:23979016)
(PMID:23979016)		 RGD PMID:23979016 MGI:5638510 NCBI chr 9:64,447,075...64,514,013
Ensembl chr 9:64,457,165...64,515,242 		JBrowse link
G Ino80e INO80 complex subunit E involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 1:181,461,406...181,472,059
Ensembl chr 1:181,461,408...181,472,469 		JBrowse link
G Mcrs1 microspherule protein 1 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 7:130,383,853...130,392,667
Ensembl chr 7:130,383,853...130,392,685 		JBrowse link
G Nfrkb nuclear factor related to kappa B binding protein involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 8:29,831,802...29,863,360
Ensembl chr 8:29,831,812...29,863,359 		JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 involved_in ISO (MGI:5638510|PMID:23979016)
(PMID:23979016)		 RGD PMID:23979016 MGI:5638510 NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 1:95,902,014...95,915,247
Ensembl chr 1:95,901,701...95,915,342 		JBrowse link
G Tfpt TCF3 fusion partner involved_in IEA
ISO		 GO_REF:0000107
(PMID:23979016)
(MGI:5638510|PMID:23979016)		 Ensembl
RGD		 PMID:23979016 GO_REF:0000107 MGI:5638510 NCBI chr 1:65,587,633...65,597,407
Ensembl chr 1:65,582,359...65,611,689 		JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 involved_in ISO (MGI:5638510|PMID:23979016)
(PMID:23979016)		 RGD PMID:23979016 MGI:5638510 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502 		JBrowse link
G Yy1 YY1 transcription factor involved_in ISO (MGI:5638510|PMID:23979016)
(PMID:23979016)		 RGD PMID:23979016 MGI:5638510 NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747 		JBrowse link
positive regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427)
(PMID:26586427)		 RGD PMID:26586427 MGI:5705431 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atr ATR serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427)
(PMID:26586427)		 RGD PMID:26586427 MGI:5705431 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(PMID:25467444)		 Ensembl
RGD		 PMID:25467444 GO_REF:0000107 NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944 		JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 acts_upstream_of ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 2:173,765,701...173,790,353
Ensembl chr 2:173,765,698...173,790,757 		JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 acts_upstream_of ISO (PMID:25467444) RGD PMID:25467444 NCBI chr14:96,991,853...97,004,732
Ensembl chr14:96,991,859...97,005,267 		JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 acts_upstream_of ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930 		JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A acts_upstream_of ISO (PMID:25467444) RGD PMID:25467444 NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 acts_upstream_of ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580 		JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 acts_upstream_of ISO (PMID:25467444) RGD PMID:25467444 NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:5428344|PMID:22723415)
(PMID:22723415)
GO_REF:0000107		 RGD
Ensembl		 PMID:22723415 GO_REF:0000107 MGI:5428344 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 acts_upstream_of_or_within ISO MGI:3849598 (PMID:15240872)
(PMID:23685356), (PMID:25467444)		 RGD PMID:15240872 PMID:23685356 PMID:25467444
G Fbxo4 F-box protein 4 involved_in ISO (PMID:16275645) RGD PMID:16275645 NCBI chr 2:53,174,798...53,187,792
Ensembl chr 2:53,174,798...53,187,792 		JBrowse link
G Gch1 GTP cyclohydrolase 1 IMP RGD PMID:30690003 RGD:401717569 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) RGD PMID:23935072 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(PMID:22633954)		 Ensembl
RGD		 PMID:22633954 GO_REF:0000107 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786 		JBrowse link
G Naf1 nuclear assembly factor 1 ribonucleoprotein acts_upstream_of ISO (PMID:27510903) RGD PMID:27510903 NCBI chr16:22,837,583...22,868,320
Ensembl chr16:22,837,588...22,868,293 		JBrowse link
G Parn poly(A)-specific ribonuclease involved_in ISO (PMID:26482878), (PMID:26950371) RGD PMID:26482878 PMID:26950371 NCBI chr10:1,410,636...1,548,573
Ensembl chr10:1,410,642...1,548,560 		JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO (PMID:12768206), (PMID:12781132), (PMID:17237768) RGD PMID:12768206 PMID:12781132 PMID:17237768 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Ptges3 prostaglandin E synthase 3 involved_in ISO (PMID:19740745) RGD PMID:19740745 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084 		JBrowse link
G Tcp1 t-complex 1 acts_upstream_of ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839 		JBrowse link
G Terc telomerase RNA component acts_upstream_of_or_within ISO MGI:1857930 (PMID:17982445) RGD PMID:17982445 NCBI chr 2:112,815,654...112,816,041 JBrowse link
G Tnks tankyrase involved_in ISO (PMID:11739745), (PMID:12782650), (PMID:18221737) RGD PMID:11739745 PMID:12782650 PMID:18221737 NCBI chr16:57,223,174...57,370,740
Ensembl chr16:57,225,094...57,366,260 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(PMID:23685356)		 Ensembl
RGD		 PMID:23685356 GO_REF:0000107 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929 		JBrowse link
positive regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO (PMID:17694070), (PMID:26586427) RGD PMID:17694070 PMID:26586427 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO (PMID:21149580) RGD PMID:21149580 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 involved_in IDA PMID:23184978 BHF-UCL PMID:23184978 RGD:11567256 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249 		JBrowse link
G Naf1 nuclear assembly factor 1 ribonucleoprotein acts_upstream_of ISO (PMID:27510903) RGD PMID:27510903 NCBI chr16:22,837,583...22,868,320
Ensembl chr16:22,837,588...22,868,293 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (PMID:23959892) RGD PMID:23959892 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
G Tnks tankyrase involved_in ISO (PMID:12782650) RGD PMID:12782650 NCBI chr16:57,223,174...57,370,740
Ensembl chr16:57,225,094...57,366,260 		JBrowse link
positive regulation of telomeric loop disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5645200|PMID:22579284)
(PMID:22579284)		 RGD PMID:22579284 MGI:5645200 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO UniProtKB:Q9NUX5 (PMID:26586433) RGD PMID:26586433 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO
IBA		 UniProtKB:Q13315 (PMID:26586433)
GO_REF:0000033		 RGD
GO_Central		 PMID:26586433 GO_REF:0000033 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Pot1b protection of telomeres 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:9,670,355...9,728,624
Ensembl chr 9:9,670,362...9,728,532 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IBA		 (PMID:19864690), (PMID:23685356)
GO_REF:0000033		 RGD
GO_Central		 PMID:19864690 PMID:23685356 GO_REF:0000033 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tinf2 TERF1 interacting nuclear factor 2 involved_in ISO
IBA		 (PMID:18669893)
GO_REF:0000033		 RGD
GO_Central		 PMID:18669893 GO_REF:0000033 NCBI chr15:29,170,663...29,178,015
Ensembl chr15:29,170,652...29,176,984 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20134
    regulation of biological process 13139
      regulation of cellular process 12763
        regulation of metabolic process 6824
          regulation of macromolecule metabolic process 6280
            regulation of DNA metabolic process 463
              regulation of telomere maintenance 101
                negative regulation of telomere maintenance + 37
                positive regulation of telomere maintenance + 70
                regulation of t-circle formation + 6
                regulation of telomere capping + 14
                regulation of telomere maintenance in response to DNA damage + 20
                regulation of telomere maintenance via recombination + 1
                regulation of telomere maintenance via semi-conservative replication + 0
                regulation of telomere maintenance via telomere lengthening + 51
                regulation of telomeric loop disassembly + 3
                regulation of telomeric loop formation + 0
Path 2
Term Annotations click to browse term
  biological_process 20134
    cellular process 19326
      metabolic process 12309
        primary metabolic process 10935
          nucleobase-containing compound metabolic process 5746
            nucleic acid metabolic process 5153
              DNA metabolic process 961
                regulation of DNA metabolic process 463
                  regulation of telomere maintenance 101
                    negative regulation of telomere maintenance + 37
                    positive regulation of telomere maintenance + 70
                    regulation of t-circle formation + 6
                    regulation of telomere capping + 14
                    regulation of telomere maintenance in response to DNA damage + 20
                    regulation of telomere maintenance via recombination + 1
                    regulation of telomere maintenance via semi-conservative replication + 0
                    regulation of telomere maintenance via telomere lengthening + 51
                    regulation of telomeric loop disassembly + 3
                    regulation of telomeric loop formation + 0
paths to the root