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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of nuclease activity
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Accession:GO:0032074 term browser browse the term
Definition:Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
Synonyms:exact_synonym: down regulation of nuclease activity;   downregulation of nuclease activity
 narrow_synonym: inhibition of nuclease activity
 related_synonym: nuclease inhibitor



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negative regulation of nuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NEIL1 nei like DNA glycosylase 1 involved_in IDA (PMID:17611195) UniProt
UniProt
PMID:17611195 NCBI chr15:75,347,039...75,357,115
Ensembl chr15:75,346,955...75,357,115
JBrowse link
negative regulation of deoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DFFA DNA fragmentation factor subunit alpha involved_in IEA
IMP
(PMID:19944011) GOC
GOC
CAFA
CAFA
PMID:19944011 GO_REF:0000108 NCBI chr 1:10,456,522...10,472,529
Ensembl chr 1:10,456,522...10,472,529
JBrowse link
negative regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GZMA granzyme A involved_in IDA (PMID:12524539) UniProt
UniProt
PMID:12524539 NCBI chr 5:55,102,646...55,110,252
Ensembl chr 5:55,102,646...55,110,252
JBrowse link
negative regulation of endoribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCE1 ATP binding cassette subfamily E member 1 involved_in IDA (PMID:7539425) GO_Central
GO_Central
PMID:7539425 NCBI chr 4:145,098,311...145,129,524
Ensembl chr 4:145,098,288...145,129,524
JBrowse link
G TMBIM6 transmembrane BAX inhibitor motif containing 6 involved_in IDA
IEA
IBA
(PMID:19328063)
(PMID:21873635)
ParkinsonsUK-UCL
ParkinsonsUK-UCL
Ensembl
GO_Central
PMID:19328063 PMID:21873635 GO_REF:0000107 NCBI chr12:49,741,557...49,764,934
Ensembl chr12:49,707,725...49,764,934
JBrowse link
negative regulation of exonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TERF1 telomeric repeat binding factor 1 involved_in IBA
IDA
(PMID:21873635)
(PMID:15200954)
GO_Central
BHF-UCL
BHF-UCL
GO_Central
PMID:15200954 PMID:21873635 NCBI chr 8:73,008,864...73,048,123
Ensembl chr 8:73,008,856...73,048,123
JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in IDA (PMID:15200954) BHF-UCL
BHF-UCL
PMID:15200954 NCBI chr16:69,355,567...69,386,007
Ensembl chr16:69,355,567...69,408,571
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19753
    metabolic process 13172
      regulation of metabolic process 7914
        regulation of macromolecule metabolic process 7338
          regulation of nuclease activity 24
            negative regulation of nuclease activity 7
              negative regulation of deoxyribonuclease activity + 2
              negative regulation of exonuclease activity + 2
              negative regulation of ribonuclease activity + 2
Path 2
Term Annotations click to browse term
  biological_process 19753
    metabolic process 13172
      cellular metabolic process 10981
        cellular aromatic compound metabolic process 6920
          nucleobase-containing compound metabolic process 6664
            regulation of nucleobase-containing compound metabolic process 4455
              negative regulation of nucleobase-containing compound metabolic process 1711
                negative regulation of nuclease activity 7
                  negative regulation of deoxyribonuclease activity + 2
                  negative regulation of exonuclease activity + 2
                  negative regulation of ribonuclease activity + 2
paths to the root