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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of nuclease activity
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Accession:GO:0032069 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
Synonyms:related_synonym: nuclease regulator activity

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negative regulation of deoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dffa DNA fragmentation factor subunit alpha involved_in ISO (PMID:19944011) RGD PMID:19944011 NCBI chr 5:165,922,893...165,935,822
Ensembl chr 5:165,922,915...165,935,821 		JBrowse link
negative regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gzma granzyme A involved_in ISO (PMID:12524539) RGD PMID:12524539 NCBI chr 2:44,968,846...44,981,436
Ensembl chr 2:44,968,765...44,981,458 		JBrowse link
negative regulation of endoribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abce1 ATP binding cassette subfamily E member 1 involved_in ISO (PMID:7539425) RGD PMID:7539425 NCBI chr19:31,867,960...31,892,863
Ensembl chr19:31,867,981...31,892,863 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3840374|PMID:19328063)
(PMID:19328063)		 Ensembl
RGD		 PMID:19328063 GO_REF:0000107 MGI:3840374 NCBI chr 7:141,039,433...141,070,269
Ensembl chr 7:141,034,982...141,069,989 		JBrowse link
negative regulation of exonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Terf1 telomeric repeat binding factor 1 involved_in ISO
IBA		 (PMID:15200954)
PMID:21873635		 RGD PMID:15200954, PMID:21873635 RGD:13792537 NCBI chr 5:2,853,455...2,882,731
Ensembl chr 5:2,853,459...2,882,668 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:15200954) RGD PMID:15200954 NCBI chr19:39,271,992...39,301,506
Ensembl chr19:39,272,499...39,300,893 		JBrowse link
negative regulation of nuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neil1 nei-like DNA glycosylase 1 involved_in ISO (PMID:17611195) RGD PMID:17611195 NCBI chr 8:61,817,258...61,824,023
Ensembl chr 8:61,817,258...61,823,102 		JBrowse link
positive regulation of deoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcna proliferating cell nuclear antigen involved_in ISO
ISS		 (PMID:19443450)
GO_REF:0000024		 RGD
UniProt		 PMID:19443450 GO_REF:0000024 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570 		JBrowse link
positive regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:20605787) RGD PMID:20605787 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Ddx11 DEAD/H-box helicase 11 involved_in ISO (PMID:18499658) RGD PMID:18499658 NCBI chr 9:114,113,642...114,133,908
Ensembl chr 9:114,111,580...114,132,492 		JBrowse link
G Prkcd protein kinase C, delta involved_in IEA
ISO		 GO_REF:0000107
(PMID:19059439)		 Ensembl
RGD		 PMID:19059439 GO_REF:0000107 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746 		JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:18973764) RGD PMID:18973764 NCBI chr 1:164,435,868...164,441,167
Ensembl chr 1:164,435,878...164,441,167 		JBrowse link
positive regulation of endoribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:20625543) RGD PMID:20625543 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:20625543) RGD PMID:20625543 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815 		JBrowse link
positive regulation of exoribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tcea1 transcription elongation factor A1 IDA RGD PMID:16046193 RGD:9693728 NCBI chr 5:14,511,183...14,548,494
Ensembl chr 5:14,511,183...14,548,429 		JBrowse link
positive regulation of nuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb2 high mobility group box 2 involved_in ISO (PMID:978439) RGD PMID:978439 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191 		JBrowse link
regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Npm1 nucleophosmin 1 involved_in ISO
ISS		 (PMID:19188445)
GO_REF:0000024		 RGD
UniProt		 PMID:19188445 GO_REF:0000024 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950 		JBrowse link
G Sirt1 sirtuin 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19934257)		 Ensembl
RGD		 PMID:19934257 GO_REF:0000107 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199 		JBrowse link
regulation of endoribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Npm1 nucleophosmin 1 involved_in ISO
ISS		 (PMID:19188445)
GO_REF:0000024		 RGD
UniProt		 PMID:19188445 GO_REF:0000024 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950 		JBrowse link
regulation of restriction endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:17803946) RGD PMID:17803946 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237 		JBrowse link
regulation of ribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in IBA
ISO		 PMID:21873635
(PMID:20844035)
(PMID:25275129)
(PMID:19923450)		 RGD PMID:19923450 PMID:20844035 PMID:25275129, PMID:21873635 RGD:13792537 NCBI chr12:41,200,680...41,211,393
Ensembl chr12:41,200,718...41,211,909 		JBrowse link
G Oas1b 2-5 oligoadenylate synthetase 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:41,255,762...41,266,430
Ensembl chr12:41,227,825...41,307,352 		JBrowse link
G Oas1d 2'-5' oligoadenylate synthetase 1D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:41,179,477...41,188,796
Ensembl chr12:41,179,477...41,188,796 		JBrowse link
G Oas1e 2'-5' oligoadenylate synthetase 1E involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:41,281,479...41,290,500
Ensembl chr12:41,281,559...41,290,497 		JBrowse link
G Oas1g 2'-5' oligoadenylate synthetase 1G involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:42,343,103...42,355,139
Ensembl chr12:42,343,123...42,355,131 		JBrowse link
G Oas1h 2 ' -5 ' oligoadenylate synthetase 1H involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:41,214,587...41,224,254
Ensembl chr12:41,214,587...41,224,254 		JBrowse link
G Oas1i 2 ' -5 ' oligoadenylate synthetase 1I involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:41,155,489...41,167,501
Ensembl chr12:41,155,497...41,167,505 		JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:41,341,417...41,363,124
Ensembl chr12:41,340,815...41,363,161 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 involved_in IBA
ISO
IEA		 PMID:21873635
(PMID:19923450), (PMID:25275129)
GO_REF:0000107		 RGD
Ensembl		 PMID:19923450 PMID:25275129, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr12:41,313,081...41,368,217
Ensembl chr12:41,316,764...41,336,562 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:47,444,138...47,456,680
Ensembl chr12:47,444,104...47,456,894 		JBrowse link
G Oasl2 2'-5' oligoadenylate synthetase-like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:47,470,074...47,483,131
Ensembl chr12:47,469,598...47,482,961 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19638
    regulation of biological process 12829
      regulation of metabolic process 6789
        regulation of macromolecule metabolic process 6293
          regulation of nuclease activity 30
            negative regulation of nuclease activity + 7
            positive regulation of nuclease activity + 9
            regulation of deoxyribonuclease activity + 10
            regulation of exonuclease activity + 3
            regulation of ribonuclease activity + 17
Path 2
Term Annotations click to browse term
  biological_process 19638
    biological regulation 13583
      regulation of biological process 12829
        regulation of metabolic process 6789
          regulation of macromolecule metabolic process 6293
            regulation of nuclease activity 30
              negative regulation of nuclease activity + 7
              positive regulation of nuclease activity + 9
              regulation of deoxyribonuclease activity + 10
              regulation of exonuclease activity + 3
              regulation of ribonuclease activity + 17
paths to the root