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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of nuclease activity
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Accession:GO:0032069 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
Synonyms:related_synonym: nuclease regulator activity


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negative regulation of deoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dffa DNA fragmentation factor subunit alpha involved_in ISO (PMID:19944011) RGD PMID:19944011 NCBI chr 5:159,540,718...159,553,639
Ensembl chr 5:159,540,715...159,553,633 		JBrowse link
negative regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gzma granzyme A involved_in ISO (PMID:12524539) RGD PMID:12524539 NCBI chr 2:44,740,638...44,752,471
Ensembl chr 2:44,740,569...44,752,493 		JBrowse link
negative regulation of endoribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abce1 ATP binding cassette subfamily E member 1 involved_in ISO (PMID:7539425) RGD PMID:7539425 NCBI chr19:28,205,566...28,230,489
Ensembl chr19:28,205,555...28,230,489 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO
IBA		 (PMID:19328063)
PMID:21873635
(MGI:3840374|PMID:19328063)		 RGD PMID:19328063 PMID:21873635 MGI:3840374, RGD:13792537 NCBI chr 7:130,512,428...130,543,637
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
negative regulation of exonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Terf1 telomeric repeat binding factor 1 involved_in ISO
IBA		 (PMID:15200954)
PMID:21873635		 RGD PMID:15200954 PMID:21873635 RGD:13792537 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:15200954) RGD PMID:15200954 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
negative regulation of nuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neil1 nei-like DNA glycosylase 1 involved_in ISO (PMID:17611195) RGD PMID:17611195 NCBI chr 8:57,550,142...57,556,884
Ensembl chr 8:57,550,147...57,556,258 		JBrowse link
positive regulation of deoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcna proliferating cell nuclear antigen involved_in ISO
ISS		 (PMID:19443450)
GO_REF:0000024		 RGD
UniProt		 PMID:19443450 GO_REF:0000024 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
positive regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:20605787) RGD PMID:20605787 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ddx11 DEAD/H-box helicase 11 involved_in ISO (PMID:18499658) RGD PMID:18499658 NCBI chr 9:105,833,234...105,862,844
Ensembl chr 9:105,833,504...105,862,550 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISO (PMID:19059439) RGD PMID:19059439 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:18973764) RGD PMID:18973764 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
positive regulation of endoribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:20625543) RGD PMID:20625543
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:20625543) RGD PMID:20625543 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
positive regulation of exoribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tcea1 transcription elongation factor A1 IDA RGD PMID:16046193 RGD:9693728 NCBI chr 5:14,631,454...14,668,769
Ensembl chr 5:14,631,454...14,668,745 		JBrowse link
positive regulation of nuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb2 high mobility group box 2 involved_in ISO (PMID:978439) RGD PMID:978439 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140 		JBrowse link
regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Npm1 nucleophosmin 1 involved_in ISO
ISS		 (PMID:19188445)
GO_REF:0000024		 RGD
UniProt		 PMID:19188445 GO_REF:0000024 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:19934257) RGD PMID:19934257 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
regulation of endoribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Npm1 nucleophosmin 1 involved_in ISO
ISS		 (PMID:19188445)
GO_REF:0000024		 RGD
UniProt		 PMID:19188445 GO_REF:0000024 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
regulation of restriction endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:17803946) RGD PMID:17803946 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565 		JBrowse link
regulation of ribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in ISO
IBA		 (PMID:19923450)
PMID:21873635
(PMID:20844035)
(PMID:25275129)		 RGD PMID:19923450 PMID:20844035 PMID:25275129 PMID:21873635 RGD:13792537 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Oas1b 2-5 oligoadenylate synthetase 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:35,724,561...35,735,271
Ensembl chr12:35,724,055...35,735,242 		JBrowse link
G Oas1d 2'-5' oligoadenylate synthetase 1D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:35,648,583...35,658,037
Ensembl chr12:35,648,583...35,657,902 		JBrowse link
G Oas1e 2'-5' oligoadenylate synthetase 1E involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:35,750,359...35,759,304
Ensembl chr12:35,750,359...35,759,301 		JBrowse link
G Oas1h 2 ' -5 ' oligoadenylate synthetase 1H involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:35,682,862...35,695,717
Ensembl chr12:35,683,699...35,693,366 		JBrowse link
G Oas1i 2 ' -5 ' oligoadenylate synthetase 1I involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:35,624,566...35,636,608
Ensembl chr12:35,624,592...35,636,604 		JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 involved_in IEA
IBA
ISO		 GO_REF:0000107
PMID:21873635
(PMID:19923450), (PMID:25275129)		 Ensembl
RGD		 PMID:19923450 PMID:25275129 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641 		JBrowse link
G Oasl2 2'-5' oligoadenylate synthetase-like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:41,710,072...41,722,687
Ensembl chr12:41,709,435...41,722,547 		JBrowse link
G Pde3a phosphodiesterase 3A involved_in ISS
ISO		 GO_REF:0000024
(PMID:34272366), (PMID:35104454)		 UniProt
RGD		 PMID:34272366 PMID:35104454 GO_REF:0000024 NCBI chr 4:174,172,804...174,443,944
Ensembl chr 4:174,172,868...174,438,274 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    regulation of biological process 12598
      regulation of metabolic process 6754
        regulation of macromolecule metabolic process 6236
          regulation of nuclease activity 30
            negative regulation of nuclease activity + 7
            positive regulation of nuclease activity + 9
            regulation of deoxyribonuclease activity + 10
            regulation of exonuclease activity + 3
            regulation of ribonuclease activity + 17
Path 2
Term Annotations click to browse term
  biological_process 18737
    biological regulation 13318
      regulation of biological process 12598
        regulation of metabolic process 6754
          regulation of macromolecule metabolic process 6236
            regulation of nuclease activity 30
              negative regulation of nuclease activity + 7
              positive regulation of nuclease activity + 9
              regulation of deoxyribonuclease activity + 10
              regulation of exonuclease activity + 3
              regulation of ribonuclease activity + 17
paths to the root