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ONTOLOGY REPORT - ANNOTATIONS


Term:bleb assembly
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Accession:GO:0032060 term browser browse the term
Definition:The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.
Synonyms:exact_synonym: cell blebbing;   plasma membrane bleb assembly;   plasma membrane blebbing
 broad_synonym: blebbing;   membrane blebbing



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bleb assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano6 anoctamin 6 involved_in ISO (PMID:25651887)
(MGI:5634870|PMID:25651887)
RGD PMID:25651887 MGI:5634870 NCBI chr 7:126,933,629...127,113,589
Ensembl chr 7:126,933,936...127,113,589
JBrowse link
G Emp1 epithelial membrane protein 1 involved_in ISO (PMID:12107182) RGD PMID:12107182 NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904
JBrowse link
G Emp2 epithelial membrane protein 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:12107182)
UniProt
RGD
PMID:12107182 GO_REF:0000024 NCBI chr10:5,360,073...5,394,734
Ensembl chr10:5,360,073...5,394,733
JBrowse link
G Emp3 epithelial membrane protein 3 involved_in ISO (PMID:12107182) RGD PMID:12107182 NCBI chr 1:96,388,651...96,391,946
Ensembl chr 1:96,388,652...96,391,988
JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 acts_upstream_of_or_within ISO MGI:1929469 (MGI:3706220|PMID:17135244) RGD PMID:17135244 MGI:3706220 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895
JBrowse link
G Lpar3 lysophosphatidic acid receptor 3 acts_upstream_of_or_within ISO MGI:108429 (MGI:3706220|PMID:17135244) RGD PMID:17135244 MGI:3706220 NCBI chr 2:235,125,234...235,193,916
Ensembl chr 2:235,149,065...235,193,357
JBrowse link
G Mylk myosin light chain kinase involved_in ISO (PMID:20181817) RGD PMID:20181817 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within
ISO
IDA
IEA
(PMID:12107182)
MGI:2386080 (MGI:3706220|PMID:17135244)
(MGI:5634870|PMID:25651887)
PMID:12857854
GO_REF:0000107
RGD
Ensembl
PMID:12107182 PMID:17135244 PMID:25651887 PMID:12857854 GO_REF:0000107 MGI:3706220 MGI:5634870, RGD:8554350 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Pmp22 peripheral myelin protein 22 involved_in ISO (PMID:12107182) RGD PMID:12107182 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Prdx6 peroxiredoxin 6 acts_upstream_of_or_within ISO (MGI:3706220|PMID:17135244) RGD PMID:17135244 MGI:3706220 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3706220|PMID:17135244)
Ensembl
RGD
PMID:17135244 GO_REF:0000107 MGI:3706220 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
negative regulation of bleb assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr3 actin related protein 3 IMP RGD PMID:22786929 RGD:11571624 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124
JBrowse link
positive regulation of bleb assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anln anillin, actin binding protein involved_in ISO (PMID:23870127) RGD PMID:23870127 NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in IEA
ISO
GO_REF:0000107
(PMID:25651887)
Ensembl
RGD
PMID:25651887 GO_REF:0000107 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    cellular process 18359
      cellular component organization or biogenesis 6620
        cellular component organization 6378
          cellular component assembly 3088
            cell projection assembly 626
              plasma membrane bounded cell projection assembly 611
                bleb assembly 13
                  negative regulation of bleb assembly 1
                  positive regulation of bleb assembly 2
                  regulation of bleb assembly + 3
paths to the root