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ONTOLOGY REPORT - ANNOTATIONS

Term:cardiolipin metabolic process
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Accession:GO:0032048 term browser browse the term
Definition:The chemical reactions and pathways involving cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.
Synonyms:exact_synonym: cardiolipin metabolism
 related_synonym: diphosphatidylglycerol metabolic process;   diphosphatidylglycerol metabolism


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cardiolipin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mecp2 methyl CpG binding protein 2 acts_upstream_of_or_within IMP (PMID:17237885) MGI PMID:17237885 NCBI chr  X:73,070,198...73,129,296
Ensembl chr  X:73,070,198...73,129,296 		JBrowse link
G Pnpla8 patatin-like phospholipase domain containing 8 involved_in IMP
ISO		 (MGI:5917216|PMID:28442572) UniProt
MGI		 PMID:28442572 GO_REF:0000119 MGI:4834177 MGI:5917216 NCBI chr12:44,315,916...44,362,718
Ensembl chr12:44,268,153...44,369,315 		JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase involved_in IMP
ISO		 (MGI:4868510|PMID:21068380), (MGI:5819036|PMID:26114544) UniProt
MGI		 PMID:21068380 PMID:26114544 GO_REF:0000119 MGI:4834177 MGI:4868510 MGI:5819036 NCBI chr  X:73,325,498...73,340,182
Ensembl chr  X:73,325,518...73,333,757 		JBrowse link
cardiolipin acyl-chain remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:30,324,421...30,359,978
Ensembl chr 5:30,323,302...30,360,160 		JBrowse link
G Lclat1 lysocardiolipin acyltransferase 1 involved_in TAS (MGI:3051093|PMID:15152008) UniProt PMID:15152008 MGI:3051093 NCBI chr17:73,414,980...73,550,363
Ensembl chr17:73,414,980...73,550,363 		JBrowse link
G Pla2g5 phospholipase A2, group V involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:138,526,558...138,590,784
Ensembl chr 4:138,526,555...138,590,793 		JBrowse link
G Pla2g6 phospholipase A2, group VI involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 NCBI chr15:79,170,428...79,212,915
Ensembl chr15:79,170,428...79,212,590 		JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:73,325,498...73,340,182
Ensembl chr  X:73,325,518...73,333,757 		JBrowse link
G Them5 thioesterase superfamily member 5 involved_in IMP
IBA		 (MGI:5432849|PMID:22586271) UniProt
GO_Central		 PMID:22586271 GO_REF:0000033 MGI:5432849 NCBI chr 3:94,249,406...94,254,659
Ensembl chr 3:94,249,406...94,254,659 		JBrowse link
cardiolipin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crls1 cardiolipin synthase 1 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 2:132,688,557...132,708,706
Ensembl chr 2:132,688,586...132,708,705 		JBrowse link
G Pgs1 phosphatidylglycerophosphate synthase 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:117,876,505...117,914,837
Ensembl chr11:117,877,118...117,914,837 		JBrowse link
G Pla2g6 phospholipase A2, group VI involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr15:79,170,428...79,212,915
Ensembl chr15:79,170,428...79,212,590 		JBrowse link
G Plscr3 phospholipid scramblase 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:69,734,937...69,742,884
Ensembl chr11:69,737,202...69,742,884 		JBrowse link
G Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 involved_in IMP (MGI:5288296|PMID:21641550) UniProt PMID:21641550 MGI:5288296 NCBI chr 2:90,741,057...90,748,395
Ensembl chr 2:90,739,060...90,748,389 		JBrowse link
G Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:72,021,372...72,039,951
Ensembl chr 8:72,021,526...72,039,946 		JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:73,325,498...73,340,182
Ensembl chr  X:73,325,518...73,333,757 		JBrowse link
G Tamm41 TAM41 mitochondrial translocator assembly and maintenance homolog involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:114,981,342...115,014,890
Ensembl chr 6:114,981,342...115,014,837 		JBrowse link
positive regulation of cardiolipin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase ISO RGD PMID:20348225 RGD:13432160 NCBI chr  X:73,325,498...73,340,182
Ensembl chr  X:73,325,518...73,333,757 		JBrowse link
regulation of cardiolipin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 involved_in IMP (MGI:5604945|PMID:24856930) UniProt PMID:24856930 MGI:5604945 NCBI chr 3:34,111,429...34,135,503
Ensembl chr 3:34,110,169...34,135,470 		JBrowse link
G Phb2 prohibitin 2 involved_in IMP (MGI:5604945|PMID:24856930) UniProt PMID:24856930 MGI:5604945 NCBI chr 6:124,689,252...124,693,908
Ensembl chr 6:124,689,299...124,693,913 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    metabolic process 10995
      cellular metabolic process 9652
        cellular lipid metabolic process 1096
          glycerolipid metabolic process 397
            glycerophospholipid metabolic process 283
              phosphatidylglycerol metabolic process 28
                cardiolipin metabolic process 16
                  cardiolipin acyl-chain remodeling 6
                  cardiolipin biosynthetic process 8
                  negative regulation of cardiolipin metabolic process 0
                  positive regulation of cardiolipin metabolic process 1
                  regulation of cardiolipin metabolic process + 3
Path 2
Term Annotations click to browse term
  biological_process 28573
    metabolic process 10995
      cellular metabolic process 9652
        phosphorus metabolic process 1906
          phosphate-containing compound metabolic process 1881
            phospholipid metabolic process 375
              glycerophospholipid metabolic process 283
                phosphatidylglycerol metabolic process 28
                  cardiolipin metabolic process 16
                    cardiolipin acyl-chain remodeling 6
                    cardiolipin biosynthetic process 8
                    negative regulation of cardiolipin metabolic process 0
                    positive regulation of cardiolipin metabolic process 1
                    regulation of cardiolipin metabolic process + 3
paths to the root