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ONTOLOGY REPORT - ANNOTATIONS

Term:guanyl-nucleotide exchange factor complex
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Accession:GO:0032045 term browser browse the term
Definition:A protein complex that stimulates the exchange of guanyl nucleotides associated with a GTPase.
Synonyms:related_synonym: guanine nucleotide exchange factor


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guanyl-nucleotide exchange factor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C9orf72 C9orf72-SMCR8 complex subunit located_in
part_of		 ISO
IEA		 (PMID:29950492) ComplexPortal
Ensembl		 PMID:29950492 GO_REF:0000107 NCBI chr10:38,389,366...38,415,903
Ensembl chr10:38,389,331...38,415,901 		JBrowse link
G DGKI diacylglycerol kinase iota part_of IEA Ensembl GO_REF:0000107 NCBI chr18:11,705,055...12,187,098
Ensembl chr18:11,705,093...12,177,267 		JBrowse link
G DOCK1 dedicator of cytokinesis 1 part_of ISO (PMID:12134158) WB PMID:12134158 NCBI chr14:136,199,747...136,745,488
Ensembl chr14:136,257,807...136,741,882 		JBrowse link
G EIF2B3 eukaryotic translation initiation factor 2B subunit gamma part_of IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:166,353,918...166,487,581
Ensembl chr 6:166,353,934...166,494,698 		JBrowse link
G ELMO1 engulfment and cell motility 1 part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:36,755,026...37,336,095
Ensembl chr18:36,786,378...37,347,283 		JBrowse link
G KNDC1 kinase non-catalytic C-lobe domain containing 1 part_of IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr14:141,132,374...141,188,343
Ensembl chr14:141,132,350...141,188,342 		JBrowse link
G PDE3B phosphodiesterase 3B part_of IEA Ensembl GO_REF:0000107 NCBI chr 2:44,416,934...44,614,075
Ensembl chr 2:44,412,833...44,726,216 		JBrowse link
G RAP1A RAP1A, member of RAS oncogene family part_of IEA Ensembl GO_REF:0000107 NCBI chr 4:108,675,537...108,750,952
Ensembl chr 4:108,676,685...108,743,368 		JBrowse link
G RASGRP3 RAS guanyl releasing protein 3 part_of IEA Ensembl GO_REF:0000107 NCBI chr 3:106,098,541...106,213,787
Ensembl chr 3:106,099,821...106,213,728 		JBrowse link
G SMCR8 SMCR8-C9orf72 complex subunit located_in
part_of		 ISO
IEA
IBA		 (PMID:29950492) ComplexPortal
TreeGrafter
GO_Central
Ensembl		 PMID:29950492 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr12:60,435,276...60,443,525
Ensembl chr12:60,435,273...60,443,520 		JBrowse link
G WDR41 WD repeat domain 41 located_in
part_of		 ISO (PMID:29950492)
(PMID:27103069)		 ComplexPortal
HGNC		 PMID:27103069 PMID:29950492 NCBI chr 2:86,322,933...86,380,619
Ensembl chr 2:86,319,014...86,380,588 		JBrowse link
Mon1-Ccz1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCZ1 CCZ1 homolog, vacuolar protein trafficking and biogenesis associated part_of IEA InterPro GO_REF:0000002 NCBI chr 3:5,201,228...5,228,594 JBrowse link
G MON1A MON1 homolog A, secretory trafficking associated part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr13:32,426,733...32,437,735
Ensembl chr13:32,426,736...32,437,862 		JBrowse link
G MON1B MON1 homolog B, secretory trafficking associated part_of IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:10,713,721...10,725,474
Ensembl chr 6:10,713,719...10,725,457 		JBrowse link
G RMC1 regulator of MON1-CCZ1 part_of IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:108,376,763...108,403,175
Ensembl chr 6:108,376,777...108,403,169 		JBrowse link
Ragulator complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 located_in
part_of
is_active_in		 ISO
IEA
IBA		 (PMID:28935770)
(PMID:28935770), (PMID:29123114)		 ComplexPortal
Ensembl
InterPro
UniProt
TreeGrafter
GO_Central		 PMID:28935770 PMID:29123114 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:6,674,045...6,680,067
Ensembl chr 9:6,672,475...6,680,053 		JBrowse link
G LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 located_in
part_of		 ISO
IEA
IBA		 (PMID:28935770) ComplexPortal
Ensembl
GO_Central
TreeGrafter		 PMID:28935770 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:93,972,112...93,975,561
Ensembl chr 4:93,971,819...93,976,304 		JBrowse link
G LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 located_in
part_of		 ISO
IEA
IBA		 (PMID:28935770) ComplexPortal
Ensembl
TreeGrafter
GO_Central		 PMID:28935770 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:120,625,897...120,642,630
Ensembl chr 8:120,623,550...120,643,072 		JBrowse link
G LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 located_in
part_of		 ISO
IEA		 (PMID:28935770) ComplexPortal
InterPro
TreeGrafter		 PMID:28935770 GO_REF:0000002 GO_REF:0000118 NCBI chr 3:8,119,338...8,171,790
Ensembl chr 3:8,155,188...8,164,721 		JBrowse link
G LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 located_in
part_of		 ISO
ISS
IEA
IBA		 (PMID:28935770) ComplexPortal
UniProt
InterPro
Ensembl
GO_Central
TreeGrafter		 PMID:28935770 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:109,722,664...109,728,278
Ensembl chr 4:109,722,913...109,728,257 		JBrowse link
G SLC38A9 solute carrier family 38 member 9 part_of
located_in		 IEA
ISO		 (PMID:25561175), (PMID:25567906) Ensembl
UniProt		 PMID:25561175 PMID:25567906 GO_REF:0000107 NCBI chr16:34,639,575...34,858,827
Ensembl chr16:34,768,987...34,858,747 		JBrowse link
Ric1-Rgp1 guanyl-nucleotide exchange factor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RGP1 RGP1 homolog, RAB6A GEF complex partner 1 part_of IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:236,468,115...236,478,347
Ensembl chr 1:236,468,320...236,477,683 		JBrowse link
G RIC1 RIC1 homolog, RAB6A GEF complex partner 1 part_of IEA
IBA		 InterPro
TreeGrafter
GO_Central
Ensembl		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:216,382,179...216,494,815
Ensembl chr 1:216,382,128...216,494,793 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18685
    protein-containing complex 6006
      intracellular protein-containing complex 905
        guanyl-nucleotide exchange factor complex 23
          Mon1-Ccz1 complex 4
          Ragulator complex 6
          Ric1-Rgp1 guanyl-nucleotide exchange factor complex 2
paths to the root