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ONTOLOGY REPORT - ANNOTATIONS


Term:mitochondrial DNA metabolic process
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Accession:GO:0032042 term browser browse the term
Definition:The chemical reactions and pathways involving mitochondrial DNA.
Synonyms:exact_synonym: mitochondrial DNA metabolism;   mtDNA metabolic process;   mtDNA metabolism
 only_in_taxon: NCBITaxon:2759 ! Eukaryota


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mitochondrial DNA metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtnap1 mitochondrial nucleoid associated protein 1 involved_in ISO (PMID:37676315) UniProt PMID:37676315 NCBI chrNW_004936655:987,527...1,002,910
Ensembl chrNW_004936655:986,681...1,002,300
JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:25378300) MGI
Ensembl
PMID:25378300 GO_REF:0000107 NCBI chrNW_004936526:3,102,468...3,147,601
Ensembl chrNW_004936526:3,102,039...3,147,642
JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23197651) Ensembl
MGI
PMID:23197651 GO_REF:0000107 NCBI chrNW_004936541:4,988,469...5,004,110
Ensembl chrNW_004936541:4,988,368...5,003,922
JBrowse link
G Sesn2 sestrin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22958918) Ensembl
MGI
PMID:22958918 GO_REF:0000107 NCBI chrNW_004936474:12,416,652...12,436,799
Ensembl chrNW_004936474:12,416,652...12,436,814
JBrowse link
G Tk2 thymidine kinase 2 acts_upstream_of_or_within ISO (PMID:18467430) MGI PMID:18467430 NCBI chrNW_004936475:16,851,380...16,875,195
Ensembl chrNW_004936475:16,851,184...16,875,133
JBrowse link
G Top3a DNA topoisomerase III alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936741:1,809,371...1,838,711
Ensembl chrNW_004936741:1,809,909...1,838,734
JBrowse link
mitochondrial DNA catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Endog endonuclease G involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936487:16,282,115...16,285,486
Ensembl chrNW_004936487:16,282,398...16,285,418
JBrowse link
mitochondrial DNA repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chchd4 coiled-coil-helix-coiled-coil-helix domain containing 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24101517) Ensembl
MGI
PMID:24101517 GO_REF:0000107 NCBI chrNW_004936602:93,126...99,695
Ensembl chrNW_004936602:93,123...95,810
JBrowse link
G Dna2 DNA replication helicase/nuclease 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:9,843,867...9,884,248
Ensembl chrNW_004936521:9,843,900...9,883,932
JBrowse link
G Lig3 DNA ligase 3 involved_in
acts_upstream_of_or_within
ISO (PMID:21390132)
(PMID:21390131), (PMID:21390132)
BHF-UCL
MGI
PMID:21390131 PMID:21390132 NCBI chrNW_004936538:206,179...228,487
Ensembl chrNW_004936538:206,839...226,441
JBrowse link
G Mgme1 mitochondrial genome maintenance exonuclease 1 involved_in IEA UniProt GO_REF:0000104 NCBI chrNW_004936485:2,154,446...2,167,633
Ensembl chrNW_004936485:2,153,295...2,166,908
JBrowse link
G Neurl4 neuralized E3 ubiquitin protein ligase 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:35157000) MGI
Ensembl
PMID:35157000 GO_REF:0000107 NCBI chrNW_004936595:612,068...624,494
Ensembl chrNW_004936595:612,070...624,693
JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:25378300) MGI
Ensembl
PMID:25378300 GO_REF:0000107 NCBI chrNW_004936526:3,102,468...3,147,601
Ensembl chrNW_004936526:3,102,039...3,147,642
JBrowse link
G Primpol primase and DNA directed polymerase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936554:4,536,246...4,571,000
Ensembl chrNW_004936554:4,534,970...4,569,549
JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24101517) Ensembl
MGI
PMID:24101517 GO_REF:0000107 NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425
JBrowse link
mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dna2 DNA replication helicase/nuclease 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:9,843,867...9,884,248
Ensembl chrNW_004936521:9,843,900...9,883,932
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16327803) Ensembl
MGI
PMID:16327803 GO_REF:0000107 NCBI chrNW_004936694:43,898...74,939
Ensembl chrNW_004936694:44,635...74,958
JBrowse link
G Mgme1 mitochondrial genome maintenance exonuclease 1 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936485:2,154,446...2,167,633
Ensembl chrNW_004936485:2,153,295...2,166,908
JBrowse link
G Polg DNA polymerase gamma, catalytic subunit involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15888483) Ensembl
TreeGrafter
MGI
InterPro
PMID:15888483 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936483:15,178,947...15,196,277
Ensembl chrNW_004936483:15,179,342...15,195,258
JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23197651) Ensembl
TreeGrafter
MGI
PMID:23197651 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936541:4,988,469...5,004,110
Ensembl chrNW_004936541:4,988,368...5,003,922
JBrowse link
G Primpol primase and DNA directed polymerase involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936554:4,536,246...4,571,000
Ensembl chrNW_004936554:4,534,970...4,569,549
JBrowse link
G Rnaseh1 ribonuclease H1 acts_upstream_of_or_within ISO (PMID:12667461) MGI PMID:12667461 NCBI chrNW_004936532:1,700,414...1,714,689
Ensembl chrNW_004936532:1,701,227...1,714,695
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936498:815,401...848,749
Ensembl chrNW_004936498:815,399...848,793
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17486094) Ensembl
MGI
PMID:17486094 GO_REF:0000107 NCBI chrNW_004936470:41,354,387...41,401,308
Ensembl chrNW_004936470:41,354,287...41,401,317
JBrowse link
G Ssbp1 single stranded DNA binding protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936592:5,611,775...5,620,846
Ensembl chrNW_004936592:5,614,619...5,619,627
JBrowse link
G Tefm transcription elongation factor, mitochondrial NOT|involved_in ISO (PMID:21278163) UniProt PMID:21278163 NCBI chrNW_004936538:2,803,195...2,812,939
Ensembl chrNW_004936538:2,802,922...2,815,895
JBrowse link
G Tk2 thymidine kinase 2 acts_upstream_of_or_within ISO (PMID:18434326) MGI PMID:18434326 NCBI chrNW_004936475:16,851,380...16,875,195
Ensembl chrNW_004936475:16,851,184...16,875,133
JBrowse link
G Twnk twinkle mtDNA helicase involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936600:4,691,112...4,696,523
Ensembl chrNW_004936600:4,691,104...4,696,507
JBrowse link
negative regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg7 autophagy related 7 ISO RGD PMID:23800874 RGD:11557986 NCBI chrNW_004936602:1,938,720...2,179,239
Ensembl chrNW_004936602:1,935,507...2,179,256
JBrowse link
G Lig3 DNA ligase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:206,179...228,487
Ensembl chrNW_004936538:206,839...226,441
JBrowse link
positive regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Endog endonuclease G involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936487:16,282,115...16,285,486
Ensembl chrNW_004936487:16,282,398...16,285,418
JBrowse link
G Mtnap1 mitochondrial nucleoid associated protein 1 involved_in ISO (PMID:37676315) UniProt PMID:37676315 NCBI chrNW_004936655:987,527...1,002,910
Ensembl chrNW_004936655:986,681...1,002,300
JBrowse link
G Ssbp1 single stranded DNA binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936592:5,611,775...5,620,846
Ensembl chrNW_004936592:5,614,619...5,619,627
JBrowse link
regulation of mitochondrial DNA metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpv17 mitochondrial inner membrane protein MPV17 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936493:5,246,803...5,258,147
Ensembl chrNW_004936493:5,248,059...5,258,147
JBrowse link
G Stox1 storkhead box 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:9,500,443...9,554,082
Ensembl chrNW_004936521:9,500,152...9,554,082
JBrowse link
regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl4 methyltransferase 4, N6-adenosine involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936672:1,911,109...1,940,897
Ensembl chrNW_004936672:1,910,851...1,941,520
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16018
    cellular process 15627
      metabolic process 9955
        macromolecule metabolic process 8093
          nucleic acid metabolic process 4448
            DNA metabolic process 871
              mitochondrial DNA metabolic process 26
                DNA synthesis involved in mitochondrial DNA replication 0
                mitochondrial DNA catabolic process 1
                mitochondrial DNA repair 8
                mitochondrial DNA replication + 18
                mitochondrion DNA recombination 0
                negative regulation of mitochondrial DNA metabolic process + 2
                positive regulation of mitochondrial DNA metabolic process + 3
                regulation of mitochondrial DNA metabolic process + 8
Path 2
Term Annotations click to browse term
  biological_process 16018
    cellular process 15627
      cellular component organization or biogenesis 6541
        cellular component organization 6348
          organelle organization 3448
            mitochondrion organization 460
              mitochondrial genome maintenance 33
                mitochondrial DNA metabolic process 26
                  DNA synthesis involved in mitochondrial DNA replication 0
                  mitochondrial DNA catabolic process 1
                  mitochondrial DNA repair 8
                  mitochondrial DNA replication + 18
                  mitochondrion DNA recombination 0
                  negative regulation of mitochondrial DNA metabolic process + 2
                  positive regulation of mitochondrial DNA metabolic process + 3
                  regulation of mitochondrial DNA metabolic process + 8
paths to the root