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ONTOLOGY REPORT - ANNOTATIONS


Term:NAD-dependent histone H3K14 deacetylase activity
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Accession:GO:0032041 term browser browse the term
Definition:Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein.
Synonyms:exact_synonym: NAD-dependent histone H3-K14 deacetylase activity;   NAD-dependent histone deacetylase activity (H3-K14 specific)



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NAD-dependent histone H3K14 deacetylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt1 sirtuin 1 enables ISO (PMID:15469825) RGD PMID:15469825 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20890
    catalytic activity 6118
      catalytic activity, acting on a protein 2496
        protein lysine deacetylase activity 26
          NAD-dependent protein lysine deacetylase activity 7
            NAD-dependent histone deacetylase activity 6
              NAD-dependent histone H3K14 deacetylase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 20890
    catalytic activity 6118
      hydrolase activity 2630
        deacetylase activity 38
          protein lysine deacetylase activity 26
            histone deacetylase activity 26
              histone H3K deacetylase activity 4
                histone H3K14 deacetylase activity 2
                  NAD-dependent histone H3K14 deacetylase activity 1
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