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ONTOLOGY REPORT - ANNOTATIONS


Term:integrator complex
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Accession:GO:0032039 term browser browse the term
Definition:A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II.


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integrator complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07035479.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr12:16,950,728...16,958,554 JBrowse link
G Esrrb estrogen-related receptor beta colocalizes_with ISO
ISS
(MGI:MGI:5887187|PMID:26206133)
GO_REF:0000024
RGD
UniProt
PMID:26206133 GO_REF:0000024, MGI:MGI:5887187 NCBI chr 6:110,360,940...110,458,406
Ensembl chr 6:110,410,141...110,455,906
JBrowse link
G Ints1 integrator complex subunit 1 ISO (PMID:16239144) RGD PMID:16239144 NCBI chr12:16,950,704...16,974,896 JBrowse link
G Ints10 integrator complex subunit 10 ISO (PMID:16239144) RGD PMID:16239144 NCBI chr16:22,616,480...22,647,315
Ensembl chr16:22,617,388...22,647,506
JBrowse link
G Ints11 integrator complex subunit 11 ISO (PMID:16239144) RGD PMID:16239144 NCBI chr 5:173,318,435...173,336,930
Ensembl chr 5:173,318,479...173,336,930
JBrowse link
G Ints12 integrator complex subunit 12 ISO
IBA
IEA
(PMID:16239144)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:16239144, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 2:238,253,114...238,270,722
Ensembl chr 2:238,257,031...238,269,370
JBrowse link
G Ints13 integrator complex subunit 13 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:180,854,988...180,887,095
Ensembl chr 4:180,855,800...180,887,050
JBrowse link
G Ints14 integrator complex subunit 14 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:70,446,157...70,471,140
Ensembl chr 8:70,447,040...70,471,137
JBrowse link
G Ints2 integrator complex subunit 2 ISO
IBA
(PMID:16239144)
PMID:21873635
RGD PMID:16239144, PMID:21873635 RGD:13792537 NCBI chr10:73,632,805...73,690,952
Ensembl chr10:73,634,255...73,690,887
JBrowse link
G Ints3 integrator complex subunit 3 ISO (PMID:16239144) RGD PMID:16239144 NCBI chr 2:189,766,927...189,818,327
Ensembl chr 2:189,766,735...189,818,224
JBrowse link
G Ints4 integrator complex subunit 4 ISO
IBA
(PMID:16239144)
PMID:21873635
RGD PMID:16239144, PMID:21873635 RGD:13792537 NCBI chr 1:162,447,692...162,511,350
Ensembl chr 1:162,447,680...162,511,355
JBrowse link
G Ints5 integrator complex subunit 5 ISO
IBA
(PMID:16239144)
PMID:21873635
RGD PMID:16239144, PMID:21873635 RGD:13792537 NCBI chr 1:225,091,612...225,096,390
Ensembl chr 1:225,091,612...225,096,390
JBrowse link
G Ints6 integrator complex subunit 6 ISO
IBA
(PMID:16239144)
PMID:21873635
RGD PMID:16239144, PMID:21873635 RGD:13792537 NCBI chr15:45,844,050...45,929,996
Ensembl chr15:45,858,608...45,947,030
JBrowse link
G Ints6l integrator complex subunit 6 like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:158,835,334...158,887,055
Ensembl chr  X:158,835,811...158,886,220
JBrowse link
G Ints7 integrator complex subunit 7 ISO
IBA
(PMID:16239144)
PMID:21873635
RGD PMID:16239144, PMID:21873635 RGD:13792537 NCBI chr13:110,257,571...110,310,413
Ensembl chr13:110,257,571...110,310,413
JBrowse link
G Ints8 integrator complex subunit 8 ISO
IBA
(PMID:16239144)
PMID:21873635
RGD PMID:16239144, PMID:21873635 RGD:13792537 NCBI chr 5:24,446,002...24,493,819
Ensembl chr 5:24,445,886...24,493,670
JBrowse link
G Ints9 integrator complex subunit 9 ISO (PMID:16239144) RGD PMID:16239144 NCBI chr15:48,326,728...48,413,792
Ensembl chr15:48,327,461...48,411,462
JBrowse link
G LOC103689975 integrator complex subunit 1-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:18,073,980...18,082,353
Ensembl chr12:18,074,033...18,082,197
JBrowse link
G Nipbl NIPBL, cohesin loading factor ISO (MGI:MGI:5908762|PMID:28041881) RGD PMID:28041881 MGI:MGI:5908762 NCBI chr 2:57,508,830...57,676,197
Ensembl chr 2:57,509,428...57,600,820
JBrowse link
G Sem1 SEM1, 26S proteasome complex subunit colocalizes_with ISO (PMID:16239144) RGD PMID:16239144 NCBI chr 4:32,067,444...32,087,600
Ensembl chr 4:32,067,444...32,087,600
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6093
      integrator complex 20
Path 2
Term Annotations click to browse term
  cellular_component 20609
    cellular anatomical entity 20358
      organelle 13258
        membrane-bounded organelle 11449
          intracellular membrane-bounded organelle 10704
            nucleus 7183
              integrator complex 20
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.