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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of TOR signaling
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Accession:GO:0032008 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of TOR signaling.
Synonyms:exact_synonym: positive regulation of TOR signaling pathway;   positive regulation of TOR signalling pathway;   positive regulation of target of rapamycin signaling pathway;   positive regulation of target of rapamycin signalling pathway;   up regulation of TOR signaling pathway;   upregulation of TOR signaling pathway
 narrow_synonym: activation of TOR signaling pathway;   stimulation of TOR signaling pathway
 related_synonym: positive regulation of TOR signaling cascade


show annotations for term's descendants           Sort by:
positive regulation of TOR signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt3 AKT serine/threonine kinase 3 acts_upstream_of_or_within ISO MGI:3574346 (PMID:15713641) RGD PMID:15713641 NCBI chr13:91,475,839...91,758,060
Ensembl chr13:88,946,091...89,225,708 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 involved_in ISO (PMID:18337562) RGD PMID:18337562 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G ENSRNOG00000066475 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 Ensembl chr 7:1,169,039...1,178,734 JBrowse link
G F10 coagulation factor X involved_in IEA
ISO		 GO_REF:0000107
(PMID:18612547)		 Ensembl
RGD		 PMID:18612547 GO_REF:0000107 NCBI chr16:83,170,973...83,190,280
Ensembl chr16:76,468,838...76,488,141 		JBrowse link
G F3 coagulation factor III, tissue factor involved_in ISO
IEA		 (PMID:18612547)
GO_REF:0000107		 RGD
Ensembl		 PMID:18612547 GO_REF:0000107 NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G F7 coagulation factor VII involved_in ISO
IEA		 (PMID:18612547)
GO_REF:0000107		 RGD
Ensembl		 PMID:18612547 GO_REF:0000107 NCBI chr16:83,191,896...83,202,775
Ensembl chr16:76,489,717...76,500,610 		JBrowse link
G Flcn folliculin involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
MGI:3842151 (PMID:19234517)
(PMID:24081491), (PMID:24095279), (PMID:31672913), (PMID:31704029)		 UniProt
Ensembl
RGD		 PMID:19234517 PMID:24081491 PMID:24095279 PMID:31672913 PMID:31704029 GO_REF:0000024 GO_REF:0000107 NCBI chr10:45,088,164...45,107,581
Ensembl chr10:44,588,624...44,607,769 		JBrowse link
G Fnip1 folliculin interacting protein 1 involved_in ISO
IEA		 (PMID:24081491)
GO_REF:0000107		 RGD
Ensembl		 PMID:24081491 GO_REF:0000107 NCBI chr10:39,068,432...39,151,552
Ensembl chr10:38,567,729...38,650,824 		JBrowse link
G Gas6 growth arrest specific 6 involved_in IDA PMID:18374201 UniProt PMID:18374201 RGD:8554638 NCBI chr16:82,747,676...82,778,090
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Golph3 golgi phosphoprotein 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19553991)		 UniProt
RGD		 PMID:19553991 GO_REF:0000024 NCBI chr 2:63,072,610...63,103,091
Ensembl chr 2:61,348,030...61,376,049 		JBrowse link
G Hdac3 histone deacetylase 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:25190803)		 UniProt
Ensembl
RGD		 PMID:25190803 GO_REF:0000024 GO_REF:0000107 NCBI chr18:30,021,847...30,041,061
Ensembl chr18:29,770,636...29,793,856 		JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 involved_in ISO
ISS		 (PMID:23027611)
GO_REF:0000024		 RGD
UniProt		 PMID:23027611 GO_REF:0000024 NCBI chr 5:156,579,901...156,595,147
Ensembl chr 5:151,296,662...151,311,912 		JBrowse link
G Kdr kinase insert domain receptor IMP RGD PMID:18221855 RGD:2292019 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in ISO
IEA
ISS		 (PMID:20381137)
GO_REF:0000002
GO_REF:0000024		 RGD
InterPro
UniProt		 PMID:20381137 GO_REF:0000002 GO_REF:0000024 NCBI chr 1:165,684,001...165,689,698
Ensembl chr 1:156,272,064...156,291,179 		JBrowse link
G Lamtor1l1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 like 1 involved_in ISS
IEA		 GO_REF:0000024
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000024 NCBI chr  X:38,446,140...38,447,189
Ensembl chr  X:34,637,459...34,638,516 		JBrowse link
G Lamtor2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 involved_in ISO
IEA
IBA		 (PMID:20381137)
GO_REF:0000002
GO_REF:0000033		 RGD
InterPro
GO_Central		 PMID:20381137 GO_REF:0000002 GO_REF:0000033 NCBI chr 2:176,306,353...176,310,617
Ensembl chr 2:174,008,548...174,013,013 		JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 involved_in ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
(PMID:20381137)		 UniProt
Ensembl
GO_Central
RGD		 PMID:20381137 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:229,084,795...229,097,028
Ensembl chr 2:226,411,400...226,423,607 		JBrowse link
G Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 involved_in ISO
IEA
IBA		 (PMID:22980980)
GO_REF:0000002
GO_REF:0000107
GO_REF:0000033		 RGD
InterPro
Ensembl
GO_Central		 PMID:22980980 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr12:22,372,269...22,376,090
Ensembl chr12:17,258,623...17,262,480 		JBrowse link
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 involved_in ISO (PMID:22980980) RGD PMID:22980980 NCBI chr 2:197,588,242...197,593,598
Ensembl chr 2:194,900,038...194,905,395 		JBrowse link
G Lars1 leucyl-tRNA synthetase 1 involved_in ISO
IEA		 (PMID:22424946)
GO_REF:0000107		 RGD
Ensembl		 PMID:22424946 GO_REF:0000107 NCBI chr18:34,452,567...34,507,030
Ensembl chr18:34,201,549...34,255,931 		JBrowse link
G Lep leptin involved_in ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
(PMID:25060689)		 UniProt
Ensembl
GO_Central
RGD		 PMID:25060689 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lin28a lin-28 homolog A involved_in ISO
IEA		 (PMID:21962509)
GO_REF:0000107		 RGD
Ensembl		 PMID:21962509 GO_REF:0000107 NCBI chr 5:151,510,891...151,527,884
Ensembl chr 5:146,227,119...146,244,122 		JBrowse link
G Mlst8 MTOR associated protein, LST8 homolog involved_in ISO
IEA		 (PMID:15467718)
GO_REF:0000107		 RGD
Ensembl		 PMID:15467718 GO_REF:0000107 NCBI chr10:14,002,927...14,008,678
Ensembl chr10:13,498,388...13,504,128 		JBrowse link
G Reln reelin involved_in ISO (PMID:21664258) RGD PMID:21664258 NCBI chr 4:13,628,440...14,055,201
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Rheb Ras homolog, mTORC1 binding involved_in ISO
IEA
ISS		 (PMID:20381137)
GO_REF:0000107
(PMID:21336308)
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20381137 PMID:21336308 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:11,012,173...11,053,860
Ensembl chr 4:10,279,370...10,320,160 		JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 involved_in ISO
IEA		 (PMID:15467718)
GO_REF:0000107		 RGD
Ensembl		 PMID:15467718 GO_REF:0000107 NCBI chr 2:57,539,279...57,631,291
Ensembl chr 2:55,811,322...55,901,426 		JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 involved_in ISO
IEA		 (PMID:12150926), (PMID:18439900)
GO_REF:0000107		 RGD
Ensembl		 PMID:12150926 PMID:18439900 GO_REF:0000107 NCBI chr10:105,376,943...105,675,416
Ensembl chr10:104,878,487...105,176,983 		JBrowse link
G Rraga Ras-related GTP binding A involved_in ISO
IEA		 (PMID:23263183)
GO_REF:0000104
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:23263183 GO_REF:0000104 GO_REF:0000107 NCBI chr 5:106,159,335...106,160,930
Ensembl chr 5:101,112,859...101,114,510 		JBrowse link
G Rragb Ras-related GTP binding B involved_in ISO
IEA
ISS		 (PMID:22575674)
GO_REF:0000107
GO_REF:0000104
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:22575674 GO_REF:0000024 GO_REF:0000104 GO_REF:0000107 NCBI chr  X:21,560,313...21,610,550
Ensembl chr  X:18,184,992...18,234,639 		JBrowse link
G Rragc Ras-related GTP binding C involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 5:141,433,014...141,452,546
Ensembl chr 5:136,148,276...136,167,767 		JBrowse link
G Rragd Ras-related GTP binding D involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 5:52,170,234...52,205,700
Ensembl chr 5:47,373,463...47,409,356 		JBrowse link
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:148,433,344...148,446,735
Ensembl chr 4:146,875,524...146,891,173 		JBrowse link
G Sec13-ps2 SEC13 homolog, nuclear pore and COPII coat complex component, pseudogene 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:1,240,230...1,241,521
Ensembl chr18:967,394...968,680
Ensembl chr18:967,394...968,680 		JBrowse link
G Slc38a9 solute carrier family 38, member 9 involved_in ISO
ISS		 (PMID:25561175), (PMID:25567906)
GO_REF:0000024		 RGD
UniProt		 PMID:25561175 PMID:25567906 GO_REF:0000024 NCBI chr 2:46,024,731...46,102,419
Ensembl chr 2:44,291,989...44,368,955 		JBrowse link
G Smcr8 SMCR8-C9orf72 complex subunit involved_in ISO
IEA		 (PMID:28195531)
GO_REF:0000107		 RGD
Ensembl		 PMID:28195531 GO_REF:0000107 NCBI chr10:45,957,146...45,968,388
Ensembl chr10:45,457,605...45,468,876 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO UniProtKB:P05067|UniProtKB:P49768 (PMID:28802038) RGD PMID:28802038 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Wdr24 WD repeat domain 24 involved_in ISO
IEA		 (PMID:27166823)
GO_REF:0000002
GO_REF:0000107		 RGD
InterPro
Ensembl		 PMID:27166823 GO_REF:0000002 GO_REF:0000107 NCBI chr10:15,346,835...15,353,384
Ensembl chr10:14,843,728...14,848,864 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:25190803) RGD PMID:25190803 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
positive regulation of TORC1 signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:12172553), (PMID:17386266), (PMID:24529379), (PMID:30514904), (PMID:31548394), (PMID:33594058)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:12172553 PMID:17386266 PMID:24529379 PMID:30514904 PMID:31548394 More... GO_REF:0000024 GO_REF:0000107 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 involved_in ISO
IEA		 (PMID:26972053)
GO_REF:0000107		 RGD
Ensembl		 PMID:26972053 GO_REF:0000107 NCBI chr14:83,309,710...83,314,123
Ensembl chr14:79,086,136...79,090,548 		JBrowse link
G Clec16a C-type lectin domain containing 16A involved_in ISO
IEA		 (PMID:28223137)
GO_REF:0000107		 RGD
Ensembl		 PMID:28223137 GO_REF:0000107 NCBI chr10:5,434,725...5,631,246
Ensembl chr10:4,928,030...5,123,578 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 involved_in ISO (PMID:22017875), (PMID:22017877) RGD PMID:22017875 PMID:22017877 NCBI chr18:57,285,156...57,320,540
Ensembl chr18:55,017,055...55,049,271 		JBrowse link
G Ctns cystinosin, lysosomal cystine transporter involved_in ISO (PMID:26449607) RGD PMID:26449607 NCBI chr10:58,300,069...58,315,725
Ensembl chr10:57,801,456...57,817,120 		JBrowse link
G Cul3 cullin 3 involved_in ISO
IEA		 (PMID:29769719)
GO_REF:0000107		 RGD
Ensembl		 PMID:29769719 GO_REF:0000107 NCBI chr 9:89,040,987...89,118,775
Ensembl chr 9:81,592,641...81,670,462 		JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:30197302), (PMID:32561715) RGD PMID:30197302 PMID:32561715 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Flcn folliculin involved_in ISO
IEA
IBA
ISS		 (PMID:32612235), (PMID:36103527), (PMID:37079666)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024		 RGD
Ensembl
GO_Central
UniProt		 PMID:32612235 PMID:36103527 PMID:37079666 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr10:45,088,164...45,107,581
Ensembl chr10:44,588,624...44,607,769 		JBrowse link
G Fnip1 folliculin interacting protein 1 involved_in ISO
IEA		 (PMID:24081491), (PMID:37079666)
GO_REF:0000107		 RGD
Ensembl		 PMID:24081491 PMID:37079666 GO_REF:0000107 NCBI chr10:39,068,432...39,151,552
Ensembl chr10:38,567,729...38,650,824 		JBrowse link
G Fnip2 folliculin interacting protein 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19914239), (PMID:36103527)		 UniProt
RGD		 PMID:19914239 PMID:36103527 GO_REF:0000024 NCBI chr 2:166,894,726...167,006,490
Ensembl chr 2:164,598,906...164,707,901 		JBrowse link
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO MGI:109583|MGI:1919421 (PMID:29057879) RGD PMID:29057879 NCBI chr 4:133,117,346...133,808,647
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Gpr137 G protein-coupled receptor 137 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:213,558,846...213,562,422
Ensembl chr 1:204,129,636...204,133,082 		JBrowse link
G Gpr137b G protein-coupled receptor 137B involved_in ISO
IBA		 (PMID:31036939)
GO_REF:0000033		 RGD
GO_Central		 PMID:31036939 GO_REF:0000033 NCBI chr17:92,987,792...93,026,003
Ensembl chr17:85,966,921...86,041,835 		JBrowse link
G Gpr137c G protein-coupled receptor 137C involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:20,905,923...20,972,318
Ensembl chr15:18,426,223...18,490,807 		JBrowse link
G Gpr155 G protein-coupled receptor 155 involved_in ISO
IEA		 (PMID:36007018)
GO_REF:0000107		 RGD
Ensembl		 PMID:36007018 GO_REF:0000107 NCBI chr 3:78,623,931...78,677,803
Ensembl chr 3:58,216,423...58,270,275 		JBrowse link
G Klhl22 kelch-like family member 22 involved_in ISS
ISO
IBA
IEA		 GO_REF:0000024
(PMID:29769719)
GO_REF:0000033
GO_REF:0000107		 UniProt
RGD
GO_Central
Ensembl		 PMID:29769719 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr11:96,695,168...96,736,079
Ensembl chr11:83,190,891...83,231,770 		JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in ISO
ISS		 (PMID:28935770), (PMID:29123114), (PMID:29158492), (PMID:31001086), (PMID:32686708)
(PMID:30020076)
GO_REF:0000024		 RGD
UniProt		 PMID:28935770 PMID:29123114 PMID:29158492 PMID:30020076 PMID:31001086 More... GO_REF:0000024 NCBI chr 1:165,684,001...165,689,698
Ensembl chr 1:156,272,064...156,291,179 		JBrowse link
G Lamtor1l1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:38,446,140...38,447,189
Ensembl chr  X:34,637,459...34,638,516 		JBrowse link
G Lamtor2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 involved_in ISO (PMID:28935770), (PMID:29123114), (PMID:29158492) RGD PMID:28935770 PMID:29123114 PMID:29158492 NCBI chr 2:176,306,353...176,310,617
Ensembl chr 2:174,008,548...174,013,013 		JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 involved_in ISO
ISS
IEA		 (PMID:28935770), (PMID:29123114), (PMID:29158492)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:28935770 PMID:29123114 PMID:29158492 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:229,084,795...229,097,028
Ensembl chr 2:226,411,400...226,423,607 		JBrowse link
G Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 involved_in ISO
IEA		 (PMID:28935770), (PMID:29123114), (PMID:29158492)
GO_REF:0000107		 RGD
Ensembl		 PMID:28935770 PMID:29123114 PMID:29158492 GO_REF:0000107 NCBI chr12:22,372,269...22,376,090
Ensembl chr12:17,258,623...17,262,480 		JBrowse link
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 involved_in ISO
IBA		 (PMID:28935770), (PMID:29123114), (PMID:29158492)
GO_REF:0000033		 RGD
GO_Central		 PMID:28935770 PMID:29123114 PMID:29158492 GO_REF:0000033 NCBI chr 2:197,588,242...197,593,598
Ensembl chr 2:194,900,038...194,905,395 		JBrowse link
G Lars1 leucyl-tRNA synthetase 1 involved_in ISO
IEA		 (PMID:22424946)
GO_REF:0000107		 RGD
Ensembl		 PMID:22424946 GO_REF:0000107 NCBI chr18:34,452,567...34,507,030
Ensembl chr18:34,201,549...34,255,931 		JBrowse link
G Mat2a methionine adenosyltransferase 2A involved_in ISO (PMID:38006878) RGD PMID:38006878 NCBI chr 4:106,048,043...106,053,612
Ensembl chr 4:104,488,466...104,495,493 		JBrowse link
G Mios meiosis regulator for oocyte development involved_in ISO
IEA
IBA		 (PMID:35831510), (PMID:36528027)
GO_REF:0000107
(PMID:35022234)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:35022234 PMID:35831510 PMID:36528027 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:37,229,533...37,255,862
Ensembl chr 4:36,263,968...36,289,544 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:37541260)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:37541260 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:70,811,317...70,856,123
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
G Otub1 OTU deubiquitinase, ubiquitin aldehyde binding 1 involved_in ISO
ISS		 (PMID:35927303)
GO_REF:0000024		 RGD
UniProt		 PMID:35927303 GO_REF:0000024 NCBI chr 1:213,816,400...213,824,679
Ensembl chr 1:204,387,215...204,395,483 		JBrowse link
G Otud5 OTU deubiquitinase 5 involved_in ISO
IBA
IEA		 (PMID:33110214)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:33110214 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:17,296,750...17,331,257
Ensembl chr  X:14,626,164...14,659,573 		JBrowse link
G Pih1d1 PIH1 domain containing 1 involved_in ISO
IEA		 (PMID:24036451)
GO_REF:0000107		 RGD
Ensembl		 PMID:24036451 GO_REF:0000107 NCBI chr 1:104,774,562...104,781,757
Ensembl chr 1:95,639,592...95,645,290 		JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase involved_in ISO
IEA
IBA
ISS		 (PMID:31548394)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024		 RGD
Ensembl
GO_Central
UniProt		 PMID:31548394 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:7,556,496...7,560,747
Ensembl chr20:7,554,921...7,559,174 		JBrowse link
G Pip4p1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 involved_in ISO
IEA
ISS		 (PMID:29644770)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29644770 GO_REF:0000024 GO_REF:0000107 NCBI chr15:26,620,399...26,624,369
Ensembl chr15:24,146,856...24,150,702 		JBrowse link
G Prmt1 protein arginine methyltransferase 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:38006878)		 UniProt
Ensembl
RGD		 PMID:38006878 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:104,595,339...104,605,552
Ensembl chr 1:95,458,850...95,468,345 		JBrowse link
G Rbx1 ring-box 1 involved_in ISO
IEA		 (PMID:29769719)
GO_REF:0000107		 RGD
Ensembl		 PMID:29769719 GO_REF:0000107 NCBI chr 7:114,870,893...114,881,194
Ensembl chr 7:112,990,835...113,001,051 		JBrowse link
G Rheb Ras homolog, mTORC1 binding involved_in ISO
IEA
ISS		 (PMID:12172553), (PMID:12842888), (PMID:12906785), (PMID:15340059), (PMID:22819219), (PMID:24529379), (PMID:29236692), (PMID:29416044), (PMID:30514904), (PMID:32470140), (PMID:33157014)
(PMID:12820960), (PMID:16631613), (PMID:21321084)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:12172553 PMID:12820960 PMID:12842888 PMID:12906785 PMID:15340059 More... GO_REF:0000024 GO_REF:0000107 NCBI chr 4:11,012,173...11,053,860
Ensembl chr 4:10,279,370...10,320,160 		JBrowse link
G Rnf167 ring finger protein 167 involved_in ISO
IEA		 (PMID:33594058)
GO_REF:0000107		 RGD
Ensembl		 PMID:33594058 GO_REF:0000107 NCBI chr10:55,859,254...55,863,546
Ensembl chr10:55,360,543...55,364,927 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 involved_in ISO (PMID:22017876) RGD PMID:22017876 NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Rraga Ras-related GTP binding A involved_in ISS
IBA
ISO
IEA		 GO_REF:0000024
GO_REF:0000033
(PMID:25936802), (PMID:31601708), (PMID:31601764)
GO_REF:0000107		 UniProt
GO_Central
RGD
Ensembl		 PMID:25936802 PMID:31601708 PMID:31601764 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:106,159,335...106,160,930
Ensembl chr 5:101,112,859...101,114,510 		JBrowse link
G Rragb Ras-related GTP binding B involved_in ISO
IEA
IBA		 (PMID:22424946)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:22424946 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:21,560,313...21,610,550
Ensembl chr  X:18,184,992...18,234,639 		JBrowse link
G Rragc Ras-related GTP binding C involved_in IBA
ISO		 GO_REF:0000033
(PMID:26691987), (PMID:31601708), (PMID:31601764), (PMID:32612235), (PMID:34071043), (PMID:36608670), (PMID:37057673)		 GO_Central
RGD		 PMID:26691987 PMID:31601708 PMID:31601764 PMID:32612235 PMID:34071043 More... GO_REF:0000033 NCBI chr 5:141,433,014...141,452,546
Ensembl chr 5:136,148,276...136,167,767 		JBrowse link
G Rragd Ras-related GTP binding D involved_in ISO
IBA		 (PMID:22424946), (PMID:34607910)
GO_REF:0000033		 RGD
GO_Central		 PMID:22424946 PMID:34607910 GO_REF:0000033 NCBI chr 5:52,170,234...52,205,700
Ensembl chr 5:47,373,463...47,409,356 		JBrowse link
G Samtor S-adenosylmethionine sensor upstream of mTORC1 involved_in ISO
IEA		 (PMID:29123071)
GO_REF:0000107		 RGD
Ensembl		 PMID:29123071 GO_REF:0000107 NCBI chr 4:42,847,720...42,911,546
Ensembl chr 4:41,879,993...41,945,539 		JBrowse link
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component involved_in ISO
ISS		 (PMID:35831510), (PMID:36528027)
GO_REF:0000024		 RGD
UniProt		 PMID:35831510 PMID:36528027 GO_REF:0000024 NCBI chr 4:148,433,344...148,446,735
Ensembl chr 4:146,875,524...146,891,173 		JBrowse link
G Seh1l SEH1-like nucleoporin involved_in ISO
IEA		 (PMID:25457612), (PMID:35831510), (PMID:36528027)
GO_REF:0000107		 RGD
Ensembl		 PMID:25457612 PMID:35831510 PMID:36528027 GO_REF:0000107 NCBI chr18:63,612,228...63,639,852
Ensembl chr18:61,332,158...61,458,379 		JBrowse link
G Sesn2 sestrin 2 involved_in ISO
IEA		 (PMID:26449471), (PMID:26586190)
GO_REF:0000107		 RGD
Ensembl		 PMID:26449471 PMID:26586190 GO_REF:0000107 NCBI chr 5:149,986,304...150,005,255
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Shq1 SHQ1, H/ACA ribonucleoprotein assembly factor acts_upstream_of_or_within ISO
IEA		 MGI:109583|MGI:1914004 (PMID:29057879)
GO_REF:0000107		 RGD
Ensembl		 PMID:29057879 GO_REF:0000107 NCBI chr 4:134,741,190...134,861,960
Ensembl chr 4:133,213,361...133,305,586 		JBrowse link
G Sik3 SIK family kinase 3 involved_in ISO (PMID:30232230) RGD PMID:30232230 NCBI chr 8:55,208,969...55,419,138
Ensembl chr 8:46,311,989...46,522,444 		JBrowse link
G Slc38a9 solute carrier family 38, member 9 involved_in ISS
ISO		 GO_REF:0000024
(PMID:28336668), (PMID:30181260)		 UniProt
RGD		 PMID:28336668 PMID:30181260 GO_REF:0000024 NCBI chr 2:46,024,731...46,102,419
Ensembl chr 2:44,291,989...44,368,955 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:35927303) RGD PMID:35927303 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Srms src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites involved_in ISO
IEA		 (PMID:35927303)
GO_REF:0000107		 RGD
Ensembl		 PMID:35927303 GO_REF:0000107 NCBI chr 3:188,696,070...188,702,474
Ensembl chr 3:168,318,512...168,324,915 		JBrowse link
G Stambpl1 STAM binding protein-like 1 involved_in ISO
IEA
IBA		 (PMID:35114100)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:35114100 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:241,095,695...241,158,225
Ensembl chr 1:231,699,995...231,745,032 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO
IEA		 (PMID:34634301)
GO_REF:0000107		 RGD
Ensembl		 PMID:34634301 GO_REF:0000107 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO
IEA		 (PMID:29150432)
GO_REF:0000107		 RGD
Ensembl		 PMID:29150432 GO_REF:0000107 NCBI chr 7:58,963,319...58,996,357
Ensembl chr 7:57,077,830...57,110,892 		JBrowse link
G Usp32 ubiquitin specific peptidase 32 involved_in ISO (PMID:36476874) RGD PMID:36476874 NCBI chr10:70,353,310...70,538,008
Ensembl chr10:69,855,885...70,029,137 		JBrowse link
G Usp4 ubiquitin specific peptidase 4 involved_in ISO
IEA
ISS		 (PMID:30514904)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:30514904 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:117,912,576...117,957,934
Ensembl chr 8:109,036,099...109,080,427 		JBrowse link
G Wac WW domain containing adaptor with coiled-coil involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:60,617,702...60,677,771
Ensembl chr17:55,923,123...55,982,301 		JBrowse link
G Wdr24 WD repeat domain 24 involved_in ISO
IEA
IBA		 (PMID:35831510), (PMID:36528027), (PMID:36577058), (PMID:36732624)
GO_REF:0000107
(PMID:36732624)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:35831510 PMID:36528027 PMID:36577058 PMID:36732624 GO_REF:0000033 GO_REF:0000107 NCBI chr10:15,346,835...15,353,384
Ensembl chr10:14,843,728...14,848,864 		JBrowse link
G Wdr59 WD repeat domain 59 involved_in ISO
IEA
IBA		 (PMID:35831510), (PMID:36528027)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:35831510 PMID:36528027 GO_REF:0000033 GO_REF:0000107 NCBI chr19:56,321,529...56,393,195
Ensembl chr19:39,416,429...39,483,698 		JBrowse link
positive regulation of TORC2 signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISO
IEA		 (PMID:23684622), (PMID:26235620)
GO_REF:0000107		 RGD
Ensembl		 PMID:23684622 PMID:26235620 GO_REF:0000107 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:22084251) RGD PMID:22084251 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (PMID:32647003) RGD PMID:32647003 NCBI chr 7:136,455,900...136,501,384
Ensembl chr 7:134,577,482...134,622,934 		JBrowse link
G Otud5 OTU deubiquitinase 5 involved_in ISO
IEA
IBA		 (PMID:33110214)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:33110214 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:17,296,750...17,331,257
Ensembl chr  X:14,626,164...14,659,573 		JBrowse link
G Otud7b OTU deubiquitinase 7B involved_in ISO
IEA		 (PMID:28489822)
GO_REF:0000107		 RGD
Ensembl		 PMID:28489822 GO_REF:0000107 NCBI chr 2:186,350,811...186,411,461
Ensembl chr 2:183,662,163...183,718,674 		JBrowse link
G Sik3 SIK family kinase 3 involved_in ISO (PMID:30232230) RGD PMID:30232230 NCBI chr 8:55,208,969...55,419,138
Ensembl chr 8:46,311,989...46,522,444 		JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO
IEA		 (PMID:34245780)
GO_REF:0000107		 RGD
Ensembl		 PMID:34245780 GO_REF:0000107 NCBI chr 7:58,963,319...58,996,357
Ensembl chr 7:57,077,830...57,110,892 		JBrowse link
G Usp9x ubiquitin specific peptidase 9, X-linked involved_in ISO
IEA		 (PMID:33378666)
GO_REF:0000107		 RGD
Ensembl		 PMID:33378666 GO_REF:0000107 NCBI chr  X:12,261,633...12,399,780
Ensembl chr  X:9,588,825...9,696,711 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      signal transduction 7301
        intracellular signal transduction 3189
          TOR signaling 194
            positive regulation of TOR signaling 81
              positive regulation of TORC1 signaling 57
              positive regulation of TORC2 signaling 8
Path 2
Term Annotations click to browse term
  biological_process 20558
    biological regulation 13833
      regulation of biological process 13394
        signaling 7862
          signal transduction 7301
            intracellular signal transduction 3189
              TOR signaling 194
                regulation of TOR signaling 164
                  positive regulation of TOR signaling 81
                    positive regulation of TORC1 signaling 57
                    positive regulation of TORC2 signaling 8
paths to the root