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ONTOLOGY REPORT - ANNOTATIONS


Term:TOR signaling
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Accession:GO:0031929 term browser browse the term
Definition:The series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors.
Comment:Note that this term should not be confused with 'torso signaling pathway ; GO:0008293', although torso is abbreviated 'tor'.
Synonyms:exact_synonym: TOR signal transduction;   TOR signaling pathway;   TOR signalling pathway;   target of rapamycin signaling pathway;   target of rapamycin signalling pathway
 related_synonym: TOR signaling cascade



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TOR signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07029605.1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024
G Ccdc88a coiled coil domain containing 88A involved_in ISO (MGI:4411937|PMID:19778506) RGD PMID:19778506 MGI:4411937 NCBI chr14:103,104,091...103,256,112
Ensembl chr14:103,103,513...103,252,368
JBrowse link
G Cntnap2 contactin associated protein 2 involved_in ISO MGI:2677631 (MGI:6304667|PMID:30816216), (MGI:6694716|PMID:31874168) RGD PMID:30816216 PMID:31874168 MGI:6304667 MGI:6694716 NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027
JBrowse link
G Csf2 colony stimulating factor 2 involved_in ISO (PMID:24520418) RGD PMID:24520418 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Disc1 DISC1 scaffold protein involved_in ISO (MGI:4411937|PMID:19778506) RGD PMID:19778506 MGI:4411937 NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:12150926), (PMID:22578813)
UniProt
RGD
PMID:12150926 PMID:22578813 GO_REF:0000024 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 involved_in
acts_upstream_of_or_within
ISO (MGI:4820682|PMID:20347422)
(MGI:1326813|PMID:8939971)
RGD PMID:8939971 PMID:20347422 MGI:1326813 MGI:4820682 NCBI chr20:29,379,444...29,400,131
Ensembl chr20:29,382,668...29,399,946
JBrowse link
G Flcn folliculin involved_in
acts_upstream_of
ISO
ISS
(PMID:17028174)
MGI:3774414|MGI:3829641|MGI:3842151|MGI:4348628 (MGI:3772618|PMID:18182616), (MGI:3829339|PMID:18974783), (MGI:3841511|PMID:19234517), (MGI:5050037|PMID:21258407)
GO_REF:0000024
RGD
UniProt
PMID:17028174 PMID:18182616 PMID:18974783 PMID:19234517 PMID:21258407 GO_REF:0000024 MGI:3772618 MGI:3829339 MGI:3841511 MGI:5050037 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Fnip1 folliculin interacting protein 1 involved_in
acts_upstream_of
ISO
ISS
(PMID:17028174)
MGI:5437714 (MGI:5436190|PMID:22608497)
GO_REF:0000024
RGD
UniProt
PMID:17028174 PMID:22608497 GO_REF:0000024 MGI:5436190 NCBI chr10:38,567,728...38,650,824
Ensembl chr10:38,567,729...38,650,824
JBrowse link
G Gata3 GATA binding protein 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5285154|PMID:20696860)
UniProt
RGD
PMID:20696860 GO_REF:0000024 MGI:5285154 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of
involved_in
ISO
IEA
MGI:2384429 (MGI:4830408|PMID:20808783)
GO_REF:0000107
RGD
Ensembl
PMID:20808783 GO_REF:0000107 MGI:4830408 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Icmt isoprenylcysteine carboxyl methyltransferase acts_upstream_of_or_within ISO MGI:3033709 (MGI:5500993|PMID:23686339) RGD PMID:23686339 MGI:5500993 NCBI chr 5:162,804,368...162,811,129
Ensembl chr 5:162,804,368...162,811,128
JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator involved_in ISO (PMID:24532714) RGD PMID:24532714 NCBI chr10:42,191,378...42,246,361
Ensembl chr10:42,191,325...42,243,371
JBrowse link
G Meak7 MTOR associated protein, eak-7 homolog involved_in IBA
ISO
PMID:21873635
(PMID:29750193)
RGD PMID:29750193 PMID:21873635 RGD:13792537 NCBI chr19:47,813,899...47,836,830
Ensembl chr19:47,811,416...47,841,278
JBrowse link
G Mlst8 MTOR associated protein, LST8 homolog involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:13,498,377...13,504,128
Ensembl chr10:13,498,388...13,504,128
JBrowse link
G Mtm1 myotubularin 1 acts_upstream_of ISO MGI:2450997 (MGI:5510937|PMID:23695157) RGD PMID:23695157 MGI:5510937 NCBI chr 6:488,691...506,964
Ensembl chr 6:488,969...506,860
JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO
IBA
ISS
(PMID:15467718), (PMID:17028174), (PMID:18762023), (PMID:26018084), (PMID:29750193)
PMID:21873635
RNAcentral:URS0000554A4F_10090 (MGI:5825416|PMID:26160071)
GO_REF:0000024
RGD
UniProt
PMID:15467718 PMID:17028174 PMID:18762023 PMID:26018084 PMID:26160071 More... GO_REF:0000024 MGI:5825416, RGD:13792537 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Rhebl1 RHEB like 1 involved_in ISO (PMID:12869548) RGD PMID:12869548 NCBI chr 7:130,026,309...130,031,127
Ensembl chr 7:130,026,341...130,030,248
JBrowse link
G Rps6 ribosomal protein S6 involved_in ISO (PMID:16428328) RGD PMID:16428328 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 involved_in ISO
IBA
ISS
(PMID:12150926), (PMID:28178239), (PMID:29750193)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:12150926 PMID:28178239 PMID:29750193 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Rps6kb2 ribosomal protein S6 kinase B2 involved_in IBA
ISO
PMID:21873635
(PMID:29750193)
RGD PMID:29750193 PMID:21873635 RGD:13792537 NCBI chr 1:201,451,265...201,458,096
Ensembl chr 1:201,451,265...201,458,078
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 involved_in ISO
IBA
(PMID:20381137)
PMID:21873635
RGD PMID:20381137 PMID:21873635 RGD:13792537 NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983
JBrowse link
G Tiprl TOR signaling pathway regulator involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:77,527,176...77,552,026
Ensembl chr13:77,527,176...77,552,074
JBrowse link
negative regulation of macroautophagy by TORC1 signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain containing 16A involved_in ISO (PMID:28223137) RGD PMID:28223137 NCBI chr10:4,927,804...5,123,749
Ensembl chr10:4,928,030...5,123,578
JBrowse link
negative regulation of TOR signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07029605.1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024
G Akt1s1 AKT1 substrate 1 involved_in ISO
IBA
(PMID:17386266)
PMID:21873635
RGD PMID:17386266 PMID:21873635 RGD:13792537 NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like involved_in ISS
ISO
GO_REF:0000024
(MGI:5553401|PMID:24481314)
UniProt
RGD
PMID:24481314 GO_REF:0000024 MGI:5553401 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Cryba1 crystallin, beta A1 IMP RGD PMID:21993393 RGD:10059647 NCBI chr10:62,608,373...62,614,726
Ensembl chr10:62,608,383...62,614,726
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 involved_in
acts_upstream_of_or_within
IBA
ISO
IMP
IEA
PMID:21873635
(MGI:3773582|PMID:18198340)
PMID:21368030
(PMID:20166753)
GO_REF:0000107
RGD
Ensembl
PMID:18198340 PMID:20166753 PMID:21873635 PMID:21368030 GO_REF:0000107 MGI:3773582, RGD:13792537, RGD:8554300 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Depdc5 DEP domain containing 5, GATOR1 subcomplex subunit involved_in ISO (PMID:23723238) RGD PMID:23723238 NCBI chr14:77,732,297...77,862,924
Ensembl chr14:77,732,297...77,862,794
JBrowse link
G Deptor DEP domain containing MTOR-interacting protein involved_in ISO (PMID:19446321) RGD PMID:19446321 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
JBrowse link
G Endog endonuclease G involved_in ISO (PMID:33473107)
(MGI:6504770|PMID:33473107)
RGD PMID:33473107 MGI:6504770 NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932
JBrowse link
G Epm2a EPM2A glucan phosphatase, laforin acts_upstream_of_or_within ISO (PMID:20453062) RGD PMID:20453062 NCBI chr 1:5,727,111...5,845,338
Ensembl chr 1:5,727,066...5,920,555
JBrowse link
G Flcn folliculin involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:3774414|MGI:3829641|MGI:4348628 (MGI:3772618|PMID:18182616), (MGI:3829339|PMID:18974783), (MGI:5050037|PMID:21258407)
UniProt
RGD
PMID:18182616 PMID:18974783 PMID:21258407 GO_REF:0000024 MGI:3772618 MGI:3829339 MGI:5050037 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Fnip1 folliculin interacting protein 1 acts_upstream_of_or_within
involved_in
ISO
ISS
MGI:5437714 (MGI:5436190|PMID:22608497)
GO_REF:0000024
RGD
UniProt
PMID:22608497 GO_REF:0000024 MGI:5436190 NCBI chr10:38,567,728...38,650,824
Ensembl chr10:38,567,729...38,650,824
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in IBA
ISO
PMID:21873635
(MGI:4829580|PMID:20516643)
RGD PMID:20516643 PMID:21873635 MGI:4829580, RGD:13792537 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO RNAcentral:URS0000554A4F_10090 (MGI:5825416|PMID:26160071) RGD PMID:26160071 MGI:5825416 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2384429 (MGI:4830408|PMID:20808783)
Ensembl
RGD
PMID:20808783 GO_REF:0000107 MGI:4830408 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 involved_in IBA
ISO
PMID:21873635
(MGI:5306547|PMID:21336308)
RGD PMID:21336308 PMID:21873635 MGI:5306547, RGD:13792537 NCBI chr12:34,993,520...35,013,059
Ensembl chr12:34,994,092...35,013,052
JBrowse link
G Minar1 membrane integral NOTCH2 associated receptor 1 involved_in IBA
IMP
ISO
PMID:21873635
PMID:30080879
(PMID:30080879)
RGD PMID:30080879 PMID:21873635 PMID:30080879 RGD:13792537, RGD:13825189 NCBI chr 8:90,137,374...90,169,152
Ensembl chr 8:90,137,374...90,169,137
JBrowse link
G Mirlet7f-1 microRNA let7f-1 involved_in ISO (PMID:21962509) RGD PMID:21962509 NCBI chr17:16,114,130...16,114,226
Ensembl chr17:16,114,130...16,114,226
JBrowse link
G Mirlet7f2 microRNA let-7f-2 involved_in ISO (PMID:21962509) RGD PMID:21962509 NCBI chr  X:20,980,632...20,980,714
Ensembl chr  X:20,980,632...20,980,714
JBrowse link
G Mtm1 myotubularin 1 acts_upstream_of_or_within ISO MGI:2450997 (MGI:5510937|PMID:23695157) RGD PMID:23695157 MGI:5510937 NCBI chr 6:488,691...506,964
Ensembl chr 6:488,969...506,860
JBrowse link
G Nprl2 NPR2-like, GATOR1 complex subunit involved_in ISO (PMID:23723238) RGD PMID:23723238 NCBI chr 8:108,215,823...108,218,996
Ensembl chr 8:108,215,814...108,218,996
JBrowse link
G Nprl3 NPR3-like, GATOR1 complex subunit involved_in ISO (PMID:23723238) RGD PMID:23723238 NCBI chr10:15,355,361...15,395,812
Ensembl chr10:15,355,355...15,395,810
JBrowse link
G Pdcd6 programmed cell death 6 involved_in ISO (PMID:21893193) RGD PMID:21893193 NCBI chr 1:28,966,518...28,982,188
Ensembl chr 1:28,966,518...28,982,189
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3796765|PMID:18439900)
UniProt
RGD
PMID:18439900 GO_REF:0000024 MGI:3796765 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3796765|PMID:18439900)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:18439900 GO_REF:0000024 GO_REF:0000107 MGI:3796765 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
JBrowse link
G RGD1565472 similar to RIKEN cDNA 2310003P10 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr11:37,679,675...37,680,635
Ensembl chr11:37,680,010...37,680,474
JBrowse link
G Sh3bp4 SH3-domain binding protein 4 involved_in ISO
IEA
ISS
(PMID:22575674)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:22575674 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:89,660,156...89,739,163
Ensembl chr 9:89,660,156...89,739,163
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:20169165)
(MGI:4437499|PMID:20169165)
RGD PMID:20169165 MGI:4437499 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Tbc1d7 TBC1 domain family, member 7 involved_in ISO
IBA
(PMID:22795129)
(MGI:5437552|PMID:22795129)
PMID:21873635
RGD PMID:22795129 PMID:21873635 MGI:5437552, RGD:13792537 NCBI chr17:21,530,709...21,548,556
Ensembl chr17:21,531,016...21,548,553
JBrowse link
G Tmem127 transmembrane protein 127 involved_in ISO (PMID:20154675) RGD PMID:20154675 NCBI chr 3:114,466,095...114,478,894
Ensembl chr 3:114,466,171...114,477,519
JBrowse link
G Tnfaip8l1 TNF alpha induced protein 8 like 1 involved_in ISO
IBA
(MGI:5582156|PMID:21600655)
PMID:21873635
RGD PMID:21600655 PMID:21873635 MGI:5582156, RGD:13792537 NCBI chr 9:988,587...999,342
Ensembl chr 9:988,594...1,002,254
JBrowse link
G Tsc1 TSC complex subunit 1 involved_in IMP
IBA
ISO
PMID:23435171
PMID:21873635
(PMID:17308101), (PMID:22795129), (PMID:28215400)
RGD PMID:17308101 PMID:22795129 PMID:28215400 PMID:23435171 PMID:21873635 RGD:10448950, RGD:13792537 NCBI chr 3:11,969,547...12,018,591
Ensembl chr 3:11,979,729...12,015,674
JBrowse link
G Tsc2 TSC complex subunit 2 involved_in
acts_upstream_of_or_within
IDA
ISO
IBA
IEA
UniProtKB:Q61037 (PMID:22795129), (PMID:23778976)
UniProtKB:P49815 (MGI:5819337|PMID:23778976)
(MGI:3773582|PMID:18198340)
PMID:21873635
GO_REF:0000002
GO_REF:0000107
RGD
InterPro
Ensembl
PMID:18198340 PMID:22795129 PMID:23778976 PMID:12869586 PMID:21873635 GO_REF:0000002 GO_REF:0000107 MGI:3773582 MGI:5819337, RGD:1580520, RGD:13792537 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
JBrowse link
G Tsc2_v1 TSC complex subunit 2, variant 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Tsc2_v2 TSC complex subunit 2, variant 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Ubr1 ubiquitin protein ligase E3 component n-recognin 1 involved_in ISO (PMID:20298436) RGD PMID:20298436 NCBI chr 3:107,813,721...107,921,701
Ensembl chr 3:107,811,392...107,922,204
JBrowse link
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 involved_in ISO (PMID:20298436) RGD PMID:20298436 NCBI chr 9:13,982,427...14,062,315
Ensembl chr 9:13,982,329...14,062,139
JBrowse link
negative regulation of TORC1 signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alg13 ALG13, UDP-N-acetylglucosaminyltransferase subunit acts_upstream_of_or_within ISO MGI:6358168 (MGI:6306805|PMID:30872163) RGD PMID:30872163 MGI:6306805 NCBI chr  X:107,885,039...107,906,264
Ensembl chr  X:107,885,064...107,893,002
JBrowse link
G Atm ATM serine/threonine kinase involved_in IBA
ISO
PMID:21873635
(MGI:5509101|PMID:23878245)
(PMID:23878245)
RGD PMID:23878245 PMID:21873635 MGI:5509101, RGD:13792537 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Bmt2 base methyltransferase of 25S rRNA 2 homolog involved_in ISO
IBA
(PMID:29123071)
PMID:21873635
RGD PMID:29123071 PMID:21873635 RGD:13792537 NCBI chr 4:41,881,630...41,945,472
Ensembl chr 4:41,879,993...41,945,539
JBrowse link
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 involved_in ISO
IBA
ISS
(PMID:26972053)
(PMID:26972053), (PMID:33594058)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:26972053 PMID:33594058 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr14:79,086,136...79,090,549
Ensembl chr14:79,086,136...79,090,548
JBrowse link
G Castor2 cytosolic arginine sensor for mTORC1 subunit 2 involved_in ISO
IBA
(PMID:26972053)
PMID:21873635
RGD PMID:26972053 PMID:21873635 RGD:13792537 NCBI chr12:22,577,504...22,620,182
Ensembl chr12:22,577,512...22,620,182
JBrowse link
G Depdc5 DEP domain containing 5, GATOR1 subcomplex subunit involved_in ISO
IBA
(PMID:25457612), (PMID:29769719)
PMID:21873635
RGD PMID:25457612 PMID:29769719 PMID:21873635 RGD:13792537 NCBI chr14:77,732,297...77,862,924
Ensembl chr14:77,732,297...77,862,794
JBrowse link
G Deptor DEP domain containing MTOR-interacting protein involved_in ISO UniProtKB:Q96G74 (PMID:33110214) RGD PMID:33110214 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 involved_in ISO (PMID:28199306) RGD PMID:28199306 NCBI chr 4:161,684,249...161,698,315
Ensembl chr 4:161,684,249...161,698,422
JBrowse link
G Kics2 KICSTOR subunit 2 involved_in IBA
ISO
PMID:21873635
(PMID:28199306)
RGD PMID:28199306 PMID:21873635 RGD:13792537 NCBI chr 7:57,284,213...57,299,070
Ensembl chr 7:57,284,192...57,297,486
JBrowse link
G Kptn kaptin (actin binding protein) involved_in ISO (PMID:28199306) RGD PMID:28199306 NCBI chr 1:76,808,737...76,809,531 JBrowse link
G Nprl2 NPR2-like, GATOR1 complex subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:108,215,823...108,218,996
Ensembl chr 8:108,215,814...108,218,996
JBrowse link
G Nprl3 NPR3-like, GATOR1 complex subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:15,355,361...15,395,812
Ensembl chr10:15,355,355...15,395,810
JBrowse link
G Rnf152 ring finger protein 152 involved_in ISO
ISS
(PMID:25936802)
(MGI:5644195|PMID:25936802)
GO_REF:0000024
RGD
UniProt
PMID:25936802 GO_REF:0000024 MGI:5644195 NCBI chr13:21,324,039...21,403,405
Ensembl chr13:21,323,824...21,403,113
JBrowse link
G Rnf167 ring finger protein 167 involved_in ISS
ISO
GO_REF:0000024
(PMID:35114100)
UniProt
RGD
PMID:35114100 GO_REF:0000024 NCBI chr10:55,360,603...55,364,927
Ensembl chr10:55,360,543...55,364,927
JBrowse link
G Sesn1 sestrin 1 involved_in IBA
ISO
PMID:21873635
(MGI:5604284|PMID:25259925)
(PMID:18692468), (PMID:25263562)
RGD PMID:18692468 PMID:25259925 PMID:25263562 PMID:21873635 MGI:5604284, RGD:13792537 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697
JBrowse link
G Sesn2 sestrin 2 involved_in IBA
ISO
PMID:21873635
(MGI:5604284|PMID:25259925), (MGI:5688277|PMID:24947615)
(PMID:18692468), (PMID:24947615), (PMID:25263562), (PMID:25457612), (PMID:26449471), (PMID:26586190), (PMID:26612684)
RGD PMID:18692468 PMID:24947615 PMID:25259925 PMID:25263562 PMID:25457612 More... MGI:5604284 MGI:5688277, RGD:13792537 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Sesn3 sestrin 3 involved_in ISO
IBA
(PMID:25263562)
PMID:21873635
(MGI:5604284|PMID:25259925)
RGD PMID:25259925 PMID:25263562 PMID:21873635 MGI:5604284, RGD:13792537 NCBI chr 8:11,133,822...11,189,436
Ensembl chr 8:11,133,678...11,185,842
JBrowse link
G Spaar small regulatory polypeptide of amino acid response involved_in ISO (PMID:28024296)
(MGI:5822922|PMID:28024296)
RGD PMID:28024296 MGI:5822922 NCBI chr 5:57,985,569...57,991,972 JBrowse link
G Stk11 serine/threonine kinase 11 involved_in ISO (PMID:23878245) RGD PMID:23878245 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Szt2 SZT2 subunit of KICSTOR complex involved_in ISO (PMID:28199306), (PMID:28199315)
(MGI:5883356|PMID:28199306), (MGI:5897504|PMID:28199315)
RGD PMID:28199306 PMID:28199315 MGI:5883356 MGI:5897504 NCBI chr 5:131,897,250...131,943,953
Ensembl chr 5:131,897,275...131,943,904
JBrowse link
G Tsc2 TSC complex subunit 2 involved_in ISO (MGI:5509101|PMID:23878245) RGD PMID:23878245 MGI:5509101 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
JBrowse link
negative regulation of TORC2 signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Deptor DEP domain containing MTOR-interacting protein involved_in ISO UniProtKB:Q96G74 (PMID:33110214) RGD PMID:33110214 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
JBrowse link
positive regulation of TOR signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt3 AKT serine/threonine kinase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3574346 (MGI:3531618|PMID:15713641)
Ensembl
RGD
PMID:15713641 GO_REF:0000107 MGI:3531618 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
JBrowse link
G Flcn folliculin involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:3842151 (MGI:3841511|PMID:19234517)
(PMID:24081491), (PMID:24095279), (PMID:31672913), (PMID:31704029)
UniProt
RGD
PMID:19234517 PMID:24081491 PMID:24095279 PMID:31672913 PMID:31704029 GO_REF:0000024 MGI:3841511 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Fnip1 folliculin interacting protein 1 involved_in ISO (PMID:24081491) RGD PMID:24081491 NCBI chr10:38,567,728...38,650,824
Ensembl chr10:38,567,729...38,650,824
JBrowse link
G Gas6 growth arrest specific 6 involved_in IDA PMID:18374201 UniProt PMID:18374201 RGD:8554638 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Golph3 golgi phosphoprotein 3 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19553991)
UniProt
Ensembl
RGD
PMID:19553991 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:61,348,030...61,376,051
Ensembl chr 2:61,348,030...61,376,049
JBrowse link
G Hdac3 histone deacetylase 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:25190803)
UniProt
RGD
PMID:25190803 GO_REF:0000024 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 involved_in ISO
ISS
(PMID:23027611)
(MGI:5607214|PMID:23027611)
GO_REF:0000024
RGD
UniProt
PMID:23027611 GO_REF:0000024 MGI:5607214 NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912
JBrowse link
G Kdr kinase insert domain receptor IMP RGD PMID:18221855 RGD:2292019 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in ISO
ISS
(PMID:20381137)
GO_REF:0000024
RGD
UniProt
PMID:20381137 GO_REF:0000024 NCBI chr 1:156,272,116...156,277,687
Ensembl chr 1:156,272,064...156,291,179
JBrowse link
G Lamtor2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 involved_in IBA
ISO
PMID:21873635
(PMID:20381137)
RGD PMID:20381137 PMID:21873635 RGD:13792537 NCBI chr 2:174,008,556...174,011,950
Ensembl chr 2:174,008,548...174,013,013
JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:20381137)
UniProt
RGD
PMID:20381137 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:226,411,389...226,423,612
Ensembl chr 2:226,411,400...226,423,607
JBrowse link
G Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 involved_in ISO
IBA
(PMID:22980980)
PMID:21873635
RGD PMID:22980980 PMID:21873635 RGD:13792537 NCBI chr12:17,258,656...17,262,478
Ensembl chr12:17,258,623...17,262,480
JBrowse link
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 involved_in ISO (PMID:22980980) RGD PMID:22980980 NCBI chr 2:194,900,038...194,905,394
Ensembl chr 2:194,900,038...194,905,395
JBrowse link
G Lars1 leucyl-tRNA synthetase 1 involved_in ISO (PMID:22424946) RGD PMID:22424946 NCBI chr18:34,201,555...34,256,003
Ensembl chr18:34,201,549...34,255,931
JBrowse link
G Lep leptin involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:25060689)
PMID:21873635
UniProt
RGD
PMID:25060689 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lin28a lin-28 homolog A involved_in ISO (MGI:5294254|PMID:21962509) RGD PMID:21962509 MGI:5294254 NCBI chr 5:146,227,119...146,244,122
Ensembl chr 5:146,227,119...146,244,122
JBrowse link
G LOC100361543 RhoA activator C11orf59-like involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:34,637,461...34,638,516
Ensembl chr  X:34,637,459...34,638,516
JBrowse link
G Mios meiosis regulator for oocyte development involved_in ISO (PMID:23723238) RGD PMID:23723238 NCBI chr 4:36,263,419...36,289,546
Ensembl chr 4:36,263,968...36,289,544
JBrowse link
G Mlst8 MTOR associated protein, LST8 homolog involved_in ISO
IEA
(PMID:15467718)
GO_REF:0000107
RGD
Ensembl
PMID:15467718 GO_REF:0000107 NCBI chr10:13,498,377...13,504,128
Ensembl chr10:13,498,388...13,504,128
JBrowse link
G Reln reelin involved_in IEA
ISO
GO_REF:0000107
(MGI:5286805|PMID:21664258)
Ensembl
RGD
PMID:21664258 GO_REF:0000107 MGI:5286805 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
JBrowse link
G Rheb Ras homolog, mTORC1 binding involved_in ISO
IEA
ISS
(PMID:20381137)
GO_REF:0000002
(MGI:5306547|PMID:21336308)
GO_REF:0000024
RGD
InterPro
UniProt
PMID:20381137 PMID:21336308 GO_REF:0000002 GO_REF:0000024 MGI:5306547 NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 involved_in ISO (PMID:15467718) RGD PMID:15467718 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 involved_in ISO (PMID:12150926), (PMID:18439900) RGD PMID:12150926 PMID:18439900 NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983
JBrowse link
G Rraga Ras-related GTP binding A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:101,113,341...101,114,936
Ensembl chr 5:101,112,859...101,114,510
JBrowse link
G RragB Ras-related GTP binding B involved_in ISO
IBA
ISS
(PMID:22575674)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:22575674 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr  X:18,184,619...18,234,639
Ensembl chr  X:18,184,992...18,234,639
JBrowse link
G Rragc Ras-related GTP binding C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:136,148,239...136,167,773
Ensembl chr 5:136,148,276...136,167,767
JBrowse link
G Rragd Ras-related GTP binding D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:47,373,902...47,409,369
Ensembl chr 5:47,373,463...47,409,356
JBrowse link
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component involved_in ISO
IBA
(PMID:23723238)
PMID:21873635
RGD PMID:23723238 PMID:21873635 RGD:13792537 NCBI chr 4:146,877,739...146,891,130
Ensembl chr 4:146,875,524...146,891,173
JBrowse link
G Seh1l SEH1-like nucleoporin involved_in ISO (PMID:23723238) RGD PMID:23723238
G Slc38a9 solute carrier family 38, member 9 involved_in ISO
ISS
(PMID:25561175), (PMID:25567906)
GO_REF:0000024
RGD
UniProt
PMID:25561175 PMID:25567906 GO_REF:0000024 NCBI chr 2:44,291,637...44,374,897
Ensembl chr 2:44,291,989...44,368,955
JBrowse link
G Smcr8 SMCR8-C9orf72 complex subunit involved_in ISO (PMID:28195531) RGD PMID:28195531 NCBI chr10:45,457,962...45,465,101
Ensembl chr10:45,457,605...45,468,876
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO UniProtKB:P05067|UniProtKB:P49768 (MGI:5906931|PMID:28802038) RGD PMID:28802038 MGI:5906931 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Wdr24 WD repeat domain 24 involved_in ISO (PMID:23723238), (PMID:27166823) RGD PMID:23723238 PMID:27166823 NCBI chr10:14,844,089...14,848,871
Ensembl chr10:14,843,728...14,848,864
JBrowse link
G Wdr59 WD repeat domain 59 involved_in ISO (PMID:23723238) RGD PMID:23723238 NCBI chr19:39,416,432...39,483,773
Ensembl chr19:39,416,429...39,483,698
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:25190803) RGD PMID:25190803 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
positive regulation of TORC1 signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain containing 16A involved_in ISO (PMID:28223137) RGD PMID:28223137 NCBI chr10:4,927,804...5,123,749
Ensembl chr10:4,928,030...5,123,578
JBrowse link
G Ctns cystinosin, lysosomal cystine transporter involved_in ISO (MGI:6508509|PMID:26449607) RGD PMID:26449607 MGI:6508509 NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120
JBrowse link
G Flcn folliculin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Gpr137 G protein-coupled receptor 137 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:204,129,636...204,132,622
Ensembl chr 1:204,129,636...204,133,082
JBrowse link
G Gpr137b G protein-coupled receptor 137B involved_in IBA
ISO
PMID:21873635
(PMID:31036939)
RGD PMID:31036939 PMID:21873635 RGD:13792537 NCBI chr17:86,003,630...86,041,841
Ensembl chr17:85,966,921...86,041,835
JBrowse link
G Gpr137c G protein-coupled receptor 137C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:18,425,939...18,492,588
Ensembl chr15:18,426,223...18,490,807
JBrowse link
G Klhl22 kelch-like family member 22 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(MGI:6162296|PMID:29769719)
(PMID:29769719)
UniProt
RGD
PMID:29769719 PMID:21873635 GO_REF:0000024 MGI:6162296, RGD:13792537 NCBI chr11:83,190,891...83,231,746
Ensembl chr11:83,190,891...83,231,770
JBrowse link
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:194,900,038...194,905,394
Ensembl chr 2:194,900,038...194,905,395
JBrowse link
G Lars1 leucyl-tRNA synthetase 1 involved_in ISO (PMID:22424946) RGD PMID:22424946 NCBI chr18:34,201,555...34,256,003
Ensembl chr18:34,201,549...34,255,931
JBrowse link
G Mios meiosis regulator for oocyte development involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:36,263,419...36,289,546
Ensembl chr 4:36,263,968...36,289,544
JBrowse link
G Otud5 OTU deubiquitinase 5 involved_in ISO (PMID:33110214) RGD PMID:33110214 NCBI chr  X:14,626,173...14,659,331
Ensembl chr  X:14,626,164...14,659,573
JBrowse link
G Pih1d1 PIH1 domain containing 1 involved_in ISO (PMID:24036451) RGD PMID:24036451 NCBI chr 1:95,639,597...95,645,295
Ensembl chr 1:95,639,592...95,645,290
JBrowse link
G Pip4p1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 involved_in ISO
ISS
(PMID:29644770)
(MGI:6304515|PMID:29644770)
GO_REF:0000024
RGD
UniProt
PMID:29644770 GO_REF:0000024 MGI:6304515 NCBI chr15:24,146,854...24,150,739
Ensembl chr15:24,146,856...24,150,702
JBrowse link
G Rraga Ras-related GTP binding A involved_in ISO
ISS
(PMID:25936802)
GO_REF:0000024
RGD
UniProt
PMID:25936802 GO_REF:0000024 NCBI chr 5:101,113,341...101,114,936
Ensembl chr 5:101,112,859...101,114,510
JBrowse link
G RragB Ras-related GTP binding B involved_in ISO (PMID:22424946) RGD PMID:22424946 NCBI chr  X:18,184,619...18,234,639
Ensembl chr  X:18,184,992...18,234,639
JBrowse link
G Rragd Ras-related GTP binding D involved_in ISO (PMID:22424946) RGD PMID:22424946 NCBI chr 5:47,373,902...47,409,369
Ensembl chr 5:47,373,463...47,409,356
JBrowse link
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:146,877,739...146,891,130
Ensembl chr 4:146,875,524...146,891,173
JBrowse link
G Seh1l SEH1-like nucleoporin involved_in ISO (PMID:25457612) RGD PMID:25457612
G Sik3 SIK family kinase 3 involved_in ISO (PMID:30232230) RGD PMID:30232230 NCBI chr 8:46,312,253...46,522,444
Ensembl chr 8:46,311,989...46,522,444
JBrowse link
G Telo2 telomere maintenance 2 involved_in ISO (PMID:24036451) RGD PMID:24036451 NCBI chr10:14,120,491...14,135,729
Ensembl chr10:14,120,818...14,135,698
JBrowse link
G Wac WW domain containing adaptor with coiled-coil involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:55,922,686...55,984,286
Ensembl chr17:55,923,123...55,982,301
JBrowse link
G Wdr24 WD repeat domain 24 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:14,844,089...14,848,871
Ensembl chr10:14,843,728...14,848,864
JBrowse link
G Wdr59 WD repeat domain 59 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:39,416,432...39,483,773
Ensembl chr19:39,416,429...39,483,698
JBrowse link
positive regulation of TORC2 signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nckap1l NCK associated protein 1 like involved_in ISO (PMID:32647003) RGD PMID:32647003 NCBI chr 7:134,577,443...134,622,934
Ensembl chr 7:134,577,482...134,622,934
JBrowse link
G Otud5 OTU deubiquitinase 5 involved_in ISO (PMID:33110214) RGD PMID:33110214 NCBI chr  X:14,626,173...14,659,331
Ensembl chr  X:14,626,164...14,659,573
JBrowse link
G Sik3 SIK family kinase 3 involved_in ISO (PMID:30232230) RGD PMID:30232230 NCBI chr 8:46,312,253...46,522,444
Ensembl chr 8:46,311,989...46,522,444
JBrowse link
G Telo2 telomere maintenance 2 involved_in ISO (PMID:24036451) RGD PMID:24036451 NCBI chr10:14,120,491...14,135,729
Ensembl chr10:14,120,818...14,135,698
JBrowse link
G Usp9x ubiquitin specific peptidase 9, X-linked involved_in ISO (PMID:33378666) RGD PMID:33378666 NCBI chr  X:9,588,825...9,726,993
Ensembl chr  X:9,588,825...9,696,711
JBrowse link
regulation of TOR signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Araf A-Raf proto-oncogene, serine/threonine kinase involved_in ISS
ISO
GO_REF:0000024
(PMID:22609986)
UniProt
RGD
PMID:22609986 GO_REF:0000024 NCBI chr  X:1,227,392...1,292,356
Ensembl chr  X:1,227,392...1,239,073
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Fam83d family with sequence similarity 83, member D involved_in ISO
IBA
(PMID:24344117)
PMID:21873635
RGD PMID:24344117 PMID:21873635 RGD:13792537 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192
JBrowse link
G Fbxo9 f-box protein 9 involved_in ISS
ISO
GO_REF:0000024
(PMID:23263282)
UniProt
RGD
PMID:23263282 GO_REF:0000024 NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949
JBrowse link
G Flcn folliculin involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:3842151 (MGI:4461845|PMID:19843504)
UniProt
RGD
PMID:19843504 GO_REF:0000024 MGI:4461845 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Gba glucosylceramidase beta involved_in ISO (PMID:27378698)
(MGI:5817293|PMID:27378698)
RGD PMID:27378698 MGI:5817293 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Gna12 G protein subunit alpha 12 involved_in ISS
ISO
GO_REF:0000024
(MGI:5448916|PMID:22609986)
(PMID:22609986)
UniProt
RGD
PMID:22609986 GO_REF:0000024 MGI:5448916 NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 involved_in ISO (PMID:17002884) RGD PMID:17002884 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:161,684,249...161,698,315
Ensembl chr 4:161,684,249...161,698,422
JBrowse link
G Pkhd1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin involved_in ISO (PMID:19524688) RGD PMID:19524688 NCBI chr 9:22,547,396...23,037,443
Ensembl chr 9:22,549,513...23,037,381
JBrowse link
G RGD1565472 similar to RIKEN cDNA 2310003P10 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:37,679,675...37,680,635
Ensembl chr11:37,680,010...37,680,474
JBrowse link
G Rheb Ras homolog, mTORC1 binding involved_in ISO (MGI:4367675|PMID:19258434) RGD PMID:19258434 MGI:4367675 NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160
JBrowse link
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:16885344)
PMID:21873635
UniProt
RGD
PMID:16885344 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr20:31,432,636...31,583,998
Ensembl chr20:31,432,637...31,583,865
JBrowse link
G RragB Ras-related GTP binding B involved_in ISO UniProtKB:Q9HB90 (PMID:23723238) RGD PMID:23723238 NCBI chr  X:18,184,619...18,234,639
Ensembl chr  X:18,184,992...18,234,639
JBrowse link
G Rragc Ras-related GTP binding C involved_in ISO UniProtKB:Q5VZM2 (PMID:23723238) RGD PMID:23723238 NCBI chr 5:136,148,239...136,167,773
Ensembl chr 5:136,148,276...136,167,767
JBrowse link
G Slc7a1 solute carrier family 7 member 1 IMP RGD PMID:17234578 RGD:1642930 NCBI chr12:6,628,214...6,703,849
Ensembl chr12:6,628,007...6,703,849
JBrowse link
G Slc7a3 solute carrier family 7 member 3 IMP RGD PMID:17234578 RGD:1642930 NCBI chr  X:66,210,071...66,216,482
Ensembl chr  X:66,210,081...66,215,708
JBrowse link
G Tbck TBC1 domain containing kinase involved_in ISO (PMID:23977024) RGD PMID:23977024 NCBI chr 2:221,175,749...221,348,126
Ensembl chr 2:221,175,785...221,348,126
JBrowse link
G Telo2 telomere maintenance 2 involved_in ISO (PMID:23263282) RGD PMID:23263282 NCBI chr10:14,120,491...14,135,729
Ensembl chr10:14,120,818...14,135,698
JBrowse link
G Tmem127 transmembrane protein 127 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5581337 (MGI:5565633|PMID:24334765)
RGD PMID:24334765 PMID:21873635 MGI:5565633, RGD:13792537 NCBI chr 3:114,466,095...114,478,894
Ensembl chr 3:114,466,171...114,477,519
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:5906931|PMID:28802038) RGD PMID:28802038 MGI:5906931 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Tti1 TELO2 interacting protein 1 involved_in ISO (PMID:23263282) RGD PMID:23263282 NCBI chr 3:146,639,048...146,682,945
Ensembl chr 3:146,639,054...146,682,847
JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033 (MGI:3797328|PMID:18443001) RGD PMID:18443001 MGI:3797328 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110
JBrowse link
regulation of TORC1 signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:23767959) RGD PMID:23767959 NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131
JBrowse link
G Dyrk3 dual specificity tyrosine phosphorylation regulated kinase 3 involved_in ISO
IEA
ISS
(PMID:23415227)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:23415227 GO_REF:0000024 GO_REF:0000107 NCBI chr13:42,594,120...42,604,898
Ensembl chr13:42,594,121...42,604,778
JBrowse link
G RGD1359108 similar to RIKEN cDNA 3110043O21 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:5811684|PMID:27875531)
(PMID:27559131)
UniProt
Ensembl
RGD
PMID:27559131 PMID:27875531 GO_REF:0000024 GO_REF:0000107 MGI:5811684 NCBI chr 5:49,766,340...49,791,434
Ensembl chr 5:49,766,325...49,791,408
JBrowse link
G Rraga Ras-related GTP binding A involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 5:101,113,341...101,114,936
Ensembl chr 5:101,112,859...101,114,510
JBrowse link
G Rragc Ras-related GTP binding C involved_in ISO (PMID:27222292) RGD PMID:27222292 NCBI chr 5:136,148,239...136,167,773
Ensembl chr 5:136,148,276...136,167,767
JBrowse link
G Smcr8 SMCR8-C9orf72 complex subunit involved_in ISO (PMID:27559131) RGD PMID:27559131 NCBI chr10:45,457,962...45,465,101
Ensembl chr10:45,457,605...45,468,876
JBrowse link
regulation of TORC2 signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pih1d1 PIH1 domain containing 1 NOT|involved_in ISO (PMID:24036451) RGD PMID:24036451 NCBI chr 1:95,639,597...95,645,295
Ensembl chr 1:95,639,592...95,645,290
JBrowse link
TORC1 signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card11 caspase recruitment domain family, member 11 involved_in ISO (PMID:28628108) RGD PMID:28628108 NCBI chr12:13,620,979...13,758,115
Ensembl chr12:13,621,087...13,758,112
JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator involved_in ISO (PMID:25940091) RGD PMID:25940091 NCBI chr10:42,191,378...42,246,361
Ensembl chr10:42,191,325...42,243,371
JBrowse link
G Mfsd8 major facilitator superfamily domain containing 8 acts_upstream_of_or_within ISO (MGI:6155546|PMID:29514215) RGD PMID:29514215 MGI:6155546 NCBI chr 2:123,822,042...123,882,913
Ensembl chr 2:123,816,614...123,857,971
JBrowse link
G Mlst8 MTOR associated protein, LST8 homolog involved_in ISO
IEA
(PMID:12718876)
GO_REF:0000107
RGD
Ensembl
PMID:12718876 GO_REF:0000107 NCBI chr10:13,498,377...13,504,128
Ensembl chr10:13,498,388...13,504,128
JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO (PMID:12718876), (PMID:22424946), (PMID:28223137) RGD PMID:12718876 PMID:22424946 PMID:28223137 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nprl3 NPR3-like, GATOR1 complex subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:15,355,361...15,395,812
Ensembl chr10:15,355,355...15,395,810
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 involved_in IBA
ISO
PMID:21873635
(PMID:12718876)
RGD PMID:12718876 PMID:21873635 RGD:13792537 NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983
JBrowse link
TORC2 signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapkap1 MAPK associated protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:17,715,813...17,918,387
Ensembl chr 3:17,715,834...17,918,384
JBrowse link
G Prr5 proline rich 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:115,795,351...115,837,880
Ensembl chr 7:115,813,954...115,834,834
JBrowse link
G Prr5l proline rich 5 like involved_in IEA
ISO
IBA
ISS
GO_REF:0000107
(MGI:5448916|PMID:22609986)
PMID:21873635
GO_REF:0000024
(PMID:22609986)
Ensembl
RGD
UniProt
PMID:22609986 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5448916, RGD:13792537 NCBI chr 3:88,001,951...88,173,532
Ensembl chr 3:88,003,617...88,082,763
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
JBrowse link
G Sesn3 sestrin 3 involved_in ISO (MGI:5779633|PMID:25377878) RGD PMID:25377878 MGI:5779633 NCBI chr 8:11,133,822...11,189,436
Ensembl chr 8:11,133,678...11,185,842
JBrowse link
G Syap1 synapse associated protein 1 involved_in ISO
IBA
(PMID:23300339)
PMID:21873635
(MGI:6114863|PMID:23300339)
RGD PMID:23300339 PMID:21873635 MGI:6114863, RGD:13792537 NCBI chr  X:31,792,180...31,826,672
Ensembl chr  X:31,792,193...31,826,667
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18872
    signaling 7397
      signal transduction 6836
        intracellular signal transduction 2675
          TOR signaling 137
            TORC1 signaling + 55
            TORC2 signaling + 13
            negative regulation of TOR signaling + 52
            positive regulation of TOR signaling + 49
            regulation of TOR signaling + 115
Path 2
Term Annotations click to browse term
  biological_process 18872
    biological regulation 13378
      regulation of biological process 12642
        regulation of cellular process 11957
          signal transduction 6836
            intracellular signal transduction 2675
              TOR signaling 137
                TORC1 signaling + 55
                TORC2 signaling + 13
                negative regulation of TOR signaling + 52
                positive regulation of TOR signaling + 49
                regulation of TOR signaling + 115
paths to the root