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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of nervous system process
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Accession:GO:0031645 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process.
Synonyms:exact_synonym: down regulation of neurological process;   downregulation of neurological process;   negative regulation of neurological process;   negative regulation of neurological system process;   negative regulation of neurophysiological process
 narrow_synonym: inhibition of neurological process

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negative regulation of nervous system process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha acts_upstream_of_or_within ISO MGI:2445489 (MGI:2445452|PMID:11717154) RGD PMID:11717154 MGI:2445452 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 IDA negative regulation of epileptiform discharges in in vitro seizure models RGD PMID:16190896 RGD:1642508 NCBI chr 2:181,528,949...181,538,145
Ensembl chr 2:181,530,832...181,531,978 		JBrowse link
negative regulation of detection of mechanical stimulus involved in sensory perception of touch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IMP RGD PMID:22187436 RGD:13514092 NCBI chr 7:140,311,120...140,324,902
Ensembl chr 7:140,315,368...140,324,902 		JBrowse link
negative regulation of myelination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsc cathepsin C acts_upstream_of_or_within ISO MGI:5910745 (MGI:5904382|PMID:28251676) RGD PMID:28251676 MGI:5904382 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:2177666 (MGI:3583403|PMID:15911877) RGD PMID:15911877 MGI:3583403 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694 		JBrowse link
G Fig4 FIG4 phosphoinositide 5-phosphatase acts_upstream_of_or_within ISO MGI:1924366|MGI:3716838 (MGI:5296993|PMID:22028665) RGD PMID:22028665 MGI:5296993 NCBI chr20:45,922,806...46,044,754
Ensembl chr20:45,922,806...46,044,738 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (MGI:3583403|PMID:15911877) RGD PMID:15911877 MGI:3583403 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Jam2 junctional adhesion molecule 2 involved_in ISO (MGI:5883159|PMID:27499083) RGD PMID:27499083 MGI:5883159 NCBI chr11:24,235,310...24,285,279
Ensembl chr11:24,266,345...24,285,275 		JBrowse link
G Klk8 kallikrein related-peptidase 8 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:3766680|PMID:17629414)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:17629414 GO_REF:0000024 GO_REF:0000107 MGI:3766680 NCBI chr 1:99,735,168...99,742,011
Ensembl chr 1:99,734,993...99,742,009 		JBrowse link
G Lpin1 lipin 1 IDA RGD PMID:21715287 RGD:38599010 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046 		JBrowse link
G Mtmr2 myotubularin related protein 2 acts_upstream_of_or_within ISO MGI:2143585|MGI:3513454 (MGI:4352761|PMID:19587293), (MGI:5296993|PMID:22028665) RGD PMID:19587293 PMID:22028665 MGI:4352761 MGI:5296993 NCBI chr 8:12,283,471...12,334,014
Ensembl chr 8:12,284,528...12,333,316 		JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO (MGI:4454957|PMID:20448149) RGD PMID:20448149 MGI:4454957 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832 		JBrowse link
G Tmem98 transmembrane protein 98 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6258499|PMID:30249802)		 UniProt
RGD		 PMID:30249802 GO_REF:0000024 MGI:6258499 NCBI chr10:68,173,380...68,184,289
Ensembl chr10:68,173,369...68,184,320 		JBrowse link
G Tnf tumor necrosis factor IMP RGD PMID:23982745 RGD:10450590 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in ISO
IBA		 (PMID:21725297)
PMID:21873635		 RGD PMID:21725297, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 9:20,546,159...20,621,051
Ensembl chr 9:20,546,159...20,621,051 		JBrowse link
negative regulation of neuronal action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr35 G protein-coupled receptor 35 involved_in IMP PMID:17940199 UniProt PMID:17940199, PMID:17940199 RGD:11541107, RGD:11541107 NCBI chr 9:100,129,428...100,141,269
Ensembl chr 9:100,137,881...100,138,801 		JBrowse link
G Kcnc4 potassium voltage-gated channel subfamily C member 4 IMP RGD PMID:18048010 RGD:10412022 NCBI chr 2:210,220,908...210,241,447
Ensembl chr 2:210,220,908...210,241,455 		JBrowse link
negative regulation of sensory perception of pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn3 cellular communication network factor 3 involved_in IMP PMID:22353423 UniProt PMID:22353423, PMID:22353423 RGD:10400878, RGD:10400878 NCBI chr 7:94,375,134...94,382,154
Ensembl chr 7:94,375,020...94,383,024 		JBrowse link
G Il10 interleukin 10 IDA RGD PMID:25078297 RGD:11049468 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Kcnc4 potassium voltage-gated channel subfamily C member 4 IMP RGD PMID:17855600 RGD:10411908 NCBI chr 2:210,220,908...210,241,447
Ensembl chr 2:210,220,908...210,241,455 		JBrowse link
G Tac4 tachykinin precursor 4 involved_in ISO (PMID:17655832) RGD PMID:17655832 NCBI chr10:83,081,168...83,089,487
Ensembl chr10:83,081,168...83,089,481 		JBrowse link
negative regulation of transmission of nerve impulse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avp arginine vasopressin IMP RGD PMID:16304841 RGD:2300377 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A IMP RGD PMID:16304841 RGD:2300377 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308 		JBrowse link
G Glra1 glycine receptor, alpha 1 involved_in ISO
ISS		 (PMID:11973623)
PMID:2155780		 RGD PMID:11973623, PMID:2155780, PMID:2155780 RGD:8553668, RGD:8553668 NCBI chr10:40,851,955...40,954,364
Ensembl chr10:40,855,559...40,953,651 		JBrowse link
G Hcrt hypocretin neuropeptide precursor IDA orexin A/Hcrt1 polypeptide; sympathetic nerves of brown adipose tissue RGD PMID:15746258 RGD:1600996 NCBI chr10:88,669,216...88,670,430
Ensembl chr10:88,669,214...88,670,430 		JBrowse link
G Mtnr1b melatonin receptor 1B IMP RGD PMID:15082174 RGD:9588675 NCBI chr 8:14,359,270...14,373,894
Ensembl chr 8:14,359,270...14,373,894 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20082
    multicellular organismal process 9081
      negative regulation of multicellular organismal process 1133
        negative regulation of nervous system process 25
          negative regulation of detection of mechanical stimulus involved in sensory perception of touch 1
          negative regulation of myelination 12
          negative regulation of sensory perception of bitter taste 0
          negative regulation of sensory perception of pain 4
          negative regulation of sensory perception of pain in other organism 0
          negative regulation of sensory perception of sweet taste 0
          negative regulation of transmission of nerve impulse + 7
Path 2
Term Annotations click to browse term
  biological_process 20082
    biological regulation 13906
      regulation of biological process 13141
        regulation of multicellular organismal process 2932
          regulation of system process 660
            regulation of nervous system process 194
              negative regulation of nervous system process 25
                negative regulation of detection of mechanical stimulus involved in sensory perception of touch 1
                negative regulation of myelination 12
                negative regulation of sensory perception of bitter taste 0
                negative regulation of sensory perception of pain 4
                negative regulation of sensory perception of pain in other organism 0
                negative regulation of sensory perception of sweet taste 0
                negative regulation of transmission of nerve impulse + 7
paths to the root