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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of nervous system process
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Accession:GO:0031645 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process.
Synonyms:exact_synonym: down regulation of neurological process;   downregulation of neurological process;   negative regulation of neurological process;   negative regulation of neurological system process;   negative regulation of neurophysiological process
 narrow_synonym: inhibition of neurological process


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negative regulation of nervous system process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha acts_upstream_of_or_within ISO MGI:2445489 (MGI:2445452|PMID:11717154) RGD PMID:11717154 MGI:2445452 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 IDA negative regulation of epileptiform discharges in in vitro seizure models RGD PMID:16190896 RGD:1642508 NCBI chr 2:167,901,999...167,912,165
Ensembl chr 2:167,903,879...167,905,024 		JBrowse link
negative regulation of detection of mechanical stimulus involved in sensory perception of touch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IMP RGD PMID:22187436 RGD:13514092 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074 		JBrowse link
negative regulation of myelination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsc cathepsin C acts_upstream_of_or_within ISO MGI:5910745 (MGI:5904382|PMID:28251676) RGD PMID:28251676 MGI:5904382 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:2177666 (MGI:3583403|PMID:15911877) RGD PMID:15911877 MGI:3583403 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Fig4 FIG4 phosphoinositide 5-phosphatase acts_upstream_of_or_within ISO MGI:1924366|MGI:3716838 (MGI:5296993|PMID:22028665) RGD PMID:22028665 MGI:5296993 NCBI chr20:44,600,603...44,724,047
Ensembl chr20:44,600,603...44,723,844 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (MGI:3583403|PMID:15911877) RGD PMID:15911877 MGI:3583403 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Jam2 junctional adhesion molecule 2 involved_in ISO (MGI:5883159|PMID:27499083) RGD PMID:27499083 MGI:5883159 NCBI chr11:23,830,820...23,880,071
Ensembl chr11:23,831,106...23,880,063 		JBrowse link
G Klk8 kallikrein related-peptidase 8 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3766680|PMID:17629414)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:17629414 GO_REF:0000024 GO_REF:0000107 MGI:3766680 NCBI chr 1:94,251,803...94,258,646
Ensembl chr 1:94,251,803...94,258,646 		JBrowse link
G Lpin1 lipin 1 IMP RGD PMID:21715287 RGD:38599010 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097 		JBrowse link
G Mtmr2 myotubularin related protein 2 acts_upstream_of_or_within ISO MGI:2143585|MGI:3513454 (MGI:4352761|PMID:19587293), (MGI:5296993|PMID:22028665) RGD PMID:19587293 PMID:22028665 MGI:4352761 MGI:5296993 NCBI chr 8:10,617,993...10,670,724
Ensembl chr 8:10,617,993...10,668,172 		JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO (MGI:4454957|PMID:20448149) RGD PMID:20448149 MGI:4454957 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Tmem98 transmembrane protein 98 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6258499|PMID:30249802)		 UniProt
RGD		 PMID:30249802 GO_REF:0000024 MGI:6258499 NCBI chr10:65,796,173...65,807,082
Ensembl chr10:65,796,145...65,807,079 		JBrowse link
G Tnf tumor necrosis factor IMP RGD PMID:23982745 RGD:10450590 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in IBA
ISO		 PMID:21873635
(PMID:21725297)		 RGD PMID:21725297 PMID:21873635 RGD:13792537 NCBI chr 9:17,879,156...17,954,085
Ensembl chr 9:17,879,156...17,954,085 		JBrowse link
negative regulation of neuronal action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO MGI:1926253 (MGI:3629817|PMID:15456819) RGD PMID:15456819 MGI:3629817 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Cntnap2 contactin associated protein 2 involved_in ISO MGI:2677631 (MGI:5919007|PMID:28768803) RGD PMID:28768803 MGI:5919007 NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027 		JBrowse link
G Gpr35 G protein-coupled receptor 35 involved_in IMP PMID:17940199 UniProt PMID:17940199 RGD:11541107 NCBI chr 9:93,526,691...93,539,302
Ensembl chr 9:93,527,127...93,539,299 		JBrowse link
G Kcnc4 potassium voltage-gated channel subfamily C member 4 IMP RGD PMID:18048010 RGD:10412022 NCBI chr 2:195,063,967...195,099,233
Ensembl chr 2:195,071,769...195,099,233 		JBrowse link
negative regulation of sensory perception of pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn3 cellular communication network factor 3 involved_in IMP PMID:22353423 UniProt PMID:22353423 RGD:10400878 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019 		JBrowse link
G Il10 interleukin 10 IDA RGD PMID:25078297 RGD:11049468 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Kcnc4 potassium voltage-gated channel subfamily C member 4 IMP RGD PMID:17855600 RGD:10411908 NCBI chr 2:195,063,967...195,099,233
Ensembl chr 2:195,071,769...195,099,233 		JBrowse link
G Tac4 tachykinin precursor 4 involved_in ISO (PMID:17655832) RGD PMID:17655832 NCBI chr10:80,207,824...80,216,156
Ensembl chr10:80,207,610...80,216,156 		JBrowse link
negative regulation of transmission of nerve impulse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avp arginine vasopressin IMP RGD PMID:16304841 RGD:2300377 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A IMP RGD PMID:16304841 RGD:2300377 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215 		JBrowse link
G Glra1 glycine receptor, alpha 1 involved_in ISO
ISS		 (PMID:11973623)
PMID:2155780		 RGD PMID:11973623 PMID:2155780 RGD:8553668 NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162 		JBrowse link
G Hcrt hypocretin neuropeptide precursor IDA orexin A/Hcrt1 polypeptide; sympathetic nerves of brown adipose tissue RGD PMID:15746258 RGD:1600996 NCBI chr10:85,689,992...85,691,206
Ensembl chr10:85,689,465...85,691,210 		JBrowse link
G Mtnr1b melatonin receptor 1B IMP RGD PMID:15082174 RGD:9588675 NCBI chr 8:12,638,219...12,652,737
Ensembl chr 8:12,638,219...12,652,737 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    multicellular organismal process 8861
      negative regulation of multicellular organismal process 1270
        negative regulation of nervous system process 27
          negative regulation of detection of mechanical stimulus involved in sensory perception of touch 1
          negative regulation of myelination 12
          negative regulation of sensory perception of bitter taste 0
          negative regulation of sensory perception of pain 4
          negative regulation of sensory perception of pain in another organism 0
          negative regulation of sensory perception of sweet taste 0
          negative regulation of transmission of nerve impulse + 9
Path 2
Term Annotations click to browse term
  biological_process 18734
    biological regulation 13314
      regulation of biological process 12594
        regulation of multicellular organismal process 3129
          regulation of system process 691
            regulation of nervous system process 201
              negative regulation of nervous system process 27
                negative regulation of detection of mechanical stimulus involved in sensory perception of touch 1
                negative regulation of myelination 12
                negative regulation of sensory perception of bitter taste 0
                negative regulation of sensory perception of pain 4
                negative regulation of sensory perception of pain in another organism 0
                negative regulation of sensory perception of sweet taste 0
                negative regulation of transmission of nerve impulse + 9
paths to the root