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Term:negative regulation of myelination
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Accession:GO:0031642 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
Synonyms:exact_synonym: down regulation of myelination;   downregulation of myelination
 narrow_synonym: inhibition of myelination

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negative regulation of myelination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctsc cathepsin C JBrowse link 1 151,918,514 151,949,979 RGD:1624291
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1624291
G Fig4 FIG4 phosphoinositide 5-phosphatase JBrowse link 20 45,922,806 46,044,754 RGD:1624291
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Jam2 junctional adhesion molecule 2 JBrowse link 11 24,235,310 24,285,279 RGD:1624291
G Klk8 kallikrein related-peptidase 8 JBrowse link 1 99,735,168 99,742,011 RGD:1600115
G Mtmr2 myotubularin related protein 2 JBrowse link 8 12,283,471 12,334,014 RGD:1624291
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
G Tmem98 transmembrane protein 98 JBrowse link 10 68,173,380 68,184,289 RGD:1600115
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:10450590
G Tnfrsf21 TNF receptor superfamily member 21 JBrowse link 9 20,546,159 20,621,051 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    negative regulation of biological process 5611
      negative regulation of cellular process 5082
        negative regulation of myelination 11
Path 2
Term Annotations click to browse term
  biological_process 19576
    developmental process 6694
      anatomical structure development 6153
        multicellular organism development 5621
          system development 5156
            nervous system development 2640
              ensheathment of neurons 175
                axon ensheathment 175
                  myelination 173
                    regulation of myelination 60
                      negative regulation of myelination 11
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.