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Term:negative regulation of myelination
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Accession:GO:0031642 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
Synonyms:exact_synonym: down regulation of myelination;   downregulation of myelination
 narrow_synonym: inhibition of myelination

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negative regulation of myelination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsc cathepsin C acts_upstream_of_or_within ISO MGI:5910745 (PMID:28251676) RGD PMID:28251676 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:2177666 (PMID:15911877) RGD PMID:15911877 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Fig4 FIG4 phosphoinositide 5-phosphatase acts_upstream_of_or_within ISO MGI:1924366|MGI:3716838 (PMID:22028665) RGD PMID:22028665 NCBI chr20:44,600,603...44,724,047
Ensembl chr20:44,600,603...44,723,844
JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:15911877) RGD PMID:15911877 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Jam2 junctional adhesion molecule 2 involved_in ISO (MGI:5883159|PMID:27499083) RGD PMID:27499083 MGI:5883159 NCBI chr11:23,830,820...23,880,071
Ensembl chr11:23,831,106...23,880,063
JBrowse link
G Lpin1 lipin 1 IMP RGD PMID:21715287 RGD:38599010 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Mtmr2 myotubularin related protein 2 acts_upstream_of_or_within ISO MGI:2143585|MGI:3513454 (PMID:19587293), (PMID:22028665) RGD PMID:19587293 PMID:22028665 NCBI chr 8:10,617,993...10,670,724
Ensembl chr 8:10,617,993...10,668,172
JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO (PMID:20448149) RGD PMID:20448149 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Tmem98 transmembrane protein 98 involved_in ISS
PMID:30249802 GO_REF:0000024 GO_REF:0000107 MGI:6258499 NCBI chr10:65,796,173...65,807,082
Ensembl chr10:65,796,145...65,807,079
JBrowse link
G Tnf tumor necrosis factor IMP RGD PMID:23982745 RGD:10450590 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in ISO
PMID:21725297 GO_REF:0000033 NCBI chr 9:17,879,156...17,954,085
Ensembl chr 9:17,879,156...17,954,085
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    negative regulation of biological process 5812
      negative regulation of cellular process 5413
        negative regulation of myelination 11
Path 2
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      anatomical structure development 6575
        multicellular organism development 5290
          system development 4576
            nervous system development 2835
              ensheathment of neurons 198
                axon ensheathment 198
                  myelination 196
                    regulation of myelination 64
                      negative regulation of myelination 11
paths to the root