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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of myelination
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Accession:GO:0031642 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
Synonyms:exact_synonym: down regulation of myelination;   downregulation of myelination
 narrow_synonym: inhibition of myelination


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negative regulation of myelination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsc cathepsin C acts_upstream_of_or_within ISO MGI:5910745 (MGI:5904382|PMID:28251676) RGD PMID:28251676 MGI:5904382 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:2177666 (MGI:3583403|PMID:15911877) RGD PMID:15911877 MGI:3583403 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Fig4 FIG4 phosphoinositide 5-phosphatase acts_upstream_of_or_within ISO MGI:1924366|MGI:3716838 (MGI:5296993|PMID:22028665) RGD PMID:22028665 MGI:5296993 NCBI chr20:45,922,806...46,044,754
Ensembl chr20:45,922,806...46,044,738
JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (MGI:3583403|PMID:15911877) RGD PMID:15911877 MGI:3583403 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Jam2 junctional adhesion molecule 2 involved_in ISO (MGI:5883159|PMID:27499083) RGD PMID:27499083 MGI:5883159 NCBI chr11:24,235,310...24,285,279
Ensembl chr11:24,266,345...24,285,275
JBrowse link
G Klk8 kallikrein related-peptidase 8 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3766680|PMID:17629414)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:17629414 GO_REF:0000024 GO_REF:0000107 MGI:3766680 NCBI chr 1:99,735,168...99,742,011
Ensembl chr 1:99,734,993...99,742,009
JBrowse link
G Lpin1 lipin 1 IMP RGD PMID:21715287 RGD:38599010 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G Mtmr2 myotubularin related protein 2 acts_upstream_of_or_within ISO MGI:2143585|MGI:3513454 (MGI:4352761|PMID:19587293), (MGI:5296993|PMID:22028665) RGD PMID:19587293 PMID:22028665 MGI:4352761 MGI:5296993 NCBI chr 8:12,283,471...12,334,014
Ensembl chr 8:12,284,528...12,333,316
JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO (MGI:4454957|PMID:20448149) RGD PMID:20448149 MGI:4454957 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Tmem98 transmembrane protein 98 involved_in ISS
ISO
GO_REF:0000024
(MGI:6258499|PMID:30249802)
UniProt
RGD
PMID:30249802 GO_REF:0000024 MGI:6258499 NCBI chr10:68,173,380...68,184,289
Ensembl chr10:68,173,369...68,184,320
JBrowse link
G Tnf tumor necrosis factor IMP RGD PMID:23982745 RGD:10450590 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in IBA
ISO
PMID:21873635
(PMID:21725297)
RGD PMID:21725297, PMID:21873635 RGD:13792537 NCBI chr 9:20,546,159...20,621,051
Ensembl chr 9:20,546,159...20,621,051
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19611
    negative regulation of biological process 5615
      negative regulation of cellular process 5103
        negative regulation of myelination 12
Path 2
Term Annotations click to browse term
  biological_process 19611
    developmental process 6792
      anatomical structure development 6265
        multicellular organism development 5747
          system development 5289
            nervous system development 2718
              ensheathment of neurons 176
                axon ensheathment 176
                  myelination 174
                    regulation of myelination 61
                      negative regulation of myelination 12
paths to the root