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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of myelination
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Accession:GO:0031642 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
Synonyms:exact_synonym: down regulation of myelination;   downregulation of myelination
 narrow_synonym: inhibition of myelination



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negative regulation of myelination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsc cathepsin C acts_upstream_of_or_within ISO MGI:5910745 (MGI:5904382|PMID:28251676) RGD PMID:28251676 MGI:5904382 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:2177666 (MGI:3583403|PMID:15911877) RGD PMID:15911877 MGI:3583403 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Fig4 FIG4 phosphoinositide 5-phosphatase acts_upstream_of_or_within ISO MGI:1924366|MGI:3716838 (MGI:5296993|PMID:22028665) RGD PMID:22028665 MGI:5296993 NCBI chr20:44,600,603...44,724,047
Ensembl chr20:44,600,603...44,723,844
JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (MGI:3583403|PMID:15911877) RGD PMID:15911877 MGI:3583403 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Jam2 junctional adhesion molecule 2 involved_in ISO (MGI:5883159|PMID:27499083) RGD PMID:27499083 MGI:5883159 NCBI chr11:23,830,820...23,880,071
Ensembl chr11:23,831,106...23,880,063
JBrowse link
G Klk8 kallikrein related-peptidase 8 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3766680|PMID:17629414)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:17629414 GO_REF:0000024 GO_REF:0000107 MGI:3766680 NCBI chr 1:94,251,803...94,258,646
Ensembl chr 1:94,251,803...94,258,646
JBrowse link
G Lpin1 lipin 1 IMP RGD PMID:21715287 RGD:38599010 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Mtmr2 myotubularin related protein 2 acts_upstream_of_or_within ISO MGI:2143585|MGI:3513454 (MGI:4352761|PMID:19587293), (MGI:5296993|PMID:22028665) RGD PMID:19587293 PMID:22028665 MGI:4352761 MGI:5296993 NCBI chr 8:10,617,993...10,670,724
Ensembl chr 8:10,617,993...10,668,172
JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO (MGI:4454957|PMID:20448149) RGD PMID:20448149 MGI:4454957 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Tmem98 transmembrane protein 98 involved_in ISS
ISO
GO_REF:0000024
(MGI:6258499|PMID:30249802)
UniProt
RGD
PMID:30249802 GO_REF:0000024 MGI:6258499 NCBI chr10:65,796,173...65,807,082
Ensembl chr10:65,796,145...65,807,079
JBrowse link
G Tnf tumor necrosis factor IMP RGD PMID:23982745 RGD:10450590 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in IBA
ISO
PMID:21873635
(PMID:21725297)
RGD PMID:21725297 PMID:21873635 RGD:13792537 NCBI chr 9:17,879,156...17,954,085
Ensembl chr 9:17,879,156...17,954,085
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19512
    negative regulation of biological process 5703
      negative regulation of cellular process 5142
        negative regulation of myelination 12
Path 2
Term Annotations click to browse term
  biological_process 19512
    developmental process 6931
      anatomical structure development 6346
        multicellular organism development 5773
          system development 5413
            nervous system development 2747
              ensheathment of neurons 180
                axon ensheathment 180
                  myelination 177
                    regulation of myelination 61
                      negative regulation of myelination 12
paths to the root