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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of myelination
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Accession:GO:0031641 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.


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regulation of myelination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24101522) Ensembl
MGI		 PMID:24101522 GO_REF:0000107 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G CDH2 cadherin 2 ISO RGD PMID:11414796 RGD:1626299 NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946 		JBrowse link
G CTNNB1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19515974) Ensembl
MGI		 PMID:19515974 GO_REF:0000107 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CYFIP1 cytoplasmic FMR1 interacting protein 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:31371763 GO_REF:0000107 RGD:14981598 NCBI chr15:22,867,052...22,980,898
Ensembl chr15:22,867,052...22,981,063 		JBrowse link
G DICER1 dicer 1, ribonuclease III acts_upstream_of_or_within ISO (PMID:20223197) MGI PMID:20223197 NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20448149) Ensembl
MGI		 PMID:20448149 GO_REF:0000107 NCBI chr 3:197,042,560...197,299,321
Ensembl chr 3:197,042,560...197,299,330 		JBrowse link
G HES5 hes family bHLH transcription factor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 (PMID:17006542) Ensembl
MGI
UniProt		 PMID:17006542 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:2,528,745...2,530,263
Ensembl chr 1:2,528,745...2,530,263 		JBrowse link
G KIF14 kinesin family member 14 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:200,551,497...200,620,751
Ensembl chr 1:200,551,497...200,620,751 		JBrowse link
G LGI4 leucine rich repeat LGI family member 4 involved_in IEA
IMP		 (PMID:28318499) Ensembl
UniProt		 PMID:28318499 GO_REF:0000107 NCBI chr19:35,124,513...35,135,059
Ensembl chr19:35,124,513...35,142,451 		JBrowse link
G MIR219A1 microRNA 219a-1 acts_upstream_of_or_within ISO (PMID:20223197) MGI PMID:20223197 NCBI chr 6:33,207,835...33,207,944
Ensembl chr 6:33,207,835...33,207,944 		JBrowse link
G MIR219A2 microRNA 219a-2 acts_upstream_of_or_within ISO (PMID:20223197) MGI PMID:20223197 NCBI chr 9:128,392,618...128,392,714
Ensembl chr 9:128,392,618...128,392,714 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24101522) Ensembl
MGI		 PMID:24101522 GO_REF:0000107 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G NCMAP non-compact myelin associated protein involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:24,556,087...24,609,328
Ensembl chr 1:24,556,087...24,609,328 		JBrowse link
G NKX6-2 NK6 homeobox 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:132,783,181...132,786,147
Ensembl chr10:132,783,179...132,786,147 		JBrowse link
G NSUN5 NOP2/Sun RNA methyltransferase 5 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:73,302,516...73,308,826
Ensembl chr 7:73,302,516...73,308,826 		JBrowse link
G PTN pleiotrophin involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:137,227,341...137,343,733
Ensembl chr 7:137,227,341...137,343,774 		JBrowse link
G PTPRZ1 protein tyrosine phosphatase receptor type Z1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:121,873,161...122,062,036
Ensembl chr 7:121,873,089...122,062,036 		JBrowse link
G RARA retinoic acid receptor alpha involved_in ISO
IEA		 RGD
Ensembl		 PMID:20648638 GO_REF:0000107 RGD:6771320 NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643 		JBrowse link
G RARB retinoic acid receptor beta involved_in ISO
IEA		 RGD
Ensembl		 PMID:20648638 GO_REF:0000107 RGD:6771320 NCBI chr 3:24,829,321...25,597,932
Ensembl chr 3:24,687,887...25,597,932 		JBrowse link
G RARG retinoic acid receptor gamma involved_in ISO
IEA		 RGD
Ensembl		 PMID:20648638 GO_REF:0000107 RGD:6771320 NCBI chr12:53,210,569...53,232,209
Ensembl chr12:53,210,567...53,232,980 		JBrowse link
G RXRA retinoid X receptor alpha ISO RGD PMID:20648638 RGD:6771320 NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585 		JBrowse link
G RXRB retinoid X receptor beta ISO RGD PMID:20648638 RGD:6771320 NCBI chr 6:33,193,588...33,200,853
Ensembl chr 6:33,193,588...33,200,665 		JBrowse link
G RXRG retinoid X receptor gamma ISO RGD PMID:20648638 RGD:6771320 NCBI chr 1:165,400,922...165,445,126
Ensembl chr 1:165,400,922...165,445,355 		JBrowse link
G SIRT2 sirtuin 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:38,878,555...38,899,618
Ensembl chr19:38,878,555...38,899,862 		JBrowse link
G TCF7L2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (PMID:19503085) MGI PMID:19503085 NCBI chr10:112,950,247...113,167,678
Ensembl chr10:112,950,247...113,167,678 		JBrowse link
G TENM4 teneurin transmembrane protein 4 involved_in IMP (PMID:26188006) UniProt PMID:26188006 NCBI chr11:78,652,829...79,441,030
Ensembl chr11:78,652,829...79,441,030 		JBrowse link
G TG thyroglobulin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:1508304) Ensembl
MGI		 PMID:1508304 GO_REF:0000107 NCBI chr 8:132,866,958...133,134,899
Ensembl chr 8:132,866,958...133,134,903 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B involved_in IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
G TYMP thymidine phosphorylase involved_in IMP (PMID:9924029) CAFA PMID:9924029 NCBI chr22:50,525,752...50,530,085
Ensembl chr22:50,525,752...50,530,032 		JBrowse link
G ZPR1 ZPR1 zinc finger involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:116,773,799...116,788,023
Ensembl chr11:116,773,799...116,788,039 		JBrowse link
negative regulation of myelination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTSC cathepsin C involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28251676) Ensembl
MGI		 PMID:28251676 GO_REF:0000107 NCBI chr11:88,293,592...88,337,736
Ensembl chr11:88,265,069...88,359,684 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:15911877) UniProt
MGI		 PMID:15911877 GO_REF:0000024 NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518 		JBrowse link
G FIG4 FIG4 phosphoinositide 5-phosphatase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22028665) Ensembl
MGI		 PMID:22028665 GO_REF:0000107 NCBI chr 6:109,691,296...109,825,426
Ensembl chr 6:109,690,609...109,878,098 		JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within ISO (PMID:15911877) MGI PMID:15911877 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G JAM2 junctional adhesion molecule 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr21:25,639,258...25,717,562
Ensembl chr21:25,639,258...25,717,562 		JBrowse link
G LPIN1 lipin 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:21715287 GO_REF:0000107 RGD:38599010 NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409 		JBrowse link
G MTMR2 myotubularin related protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22028665)
(PMID:19587293)		 Ensembl
MGI		 PMID:19587293 PMID:22028665 GO_REF:0000107 NCBI chr11:95,832,880...95,924,107
Ensembl chr11:95,821,766...95,925,315 		JBrowse link
G PTEN phosphatase and tensin homolog acts_upstream_of_or_within ISO (PMID:20448149) MGI PMID:20448149 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G TMEM98 transmembrane protein 98 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:32,928,153...32,944,315
Ensembl chr17:32,927,910...32,945,106 		JBrowse link
G TNF tumor necrosis factor involved_in ISO
IEA		 RGD
Ensembl		 PMID:23982745 GO_REF:0000107 RGD:10450590 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF21 TNF receptor superfamily member 21 involved_in IMP
IBA
IEA		 (PMID:21725297) UniProt
GO_Central
TreeGrafter		 PMID:21725297 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:47,231,532...47,309,905
Ensembl chr 6:47,231,532...47,309,905 		JBrowse link
positive regulation of myelination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK18 cyclin dependent kinase 18 involved_in IDA (PMID:31028571) GO_Central PMID:31028571 NCBI chr 1:205,504,669...205,532,790
Ensembl chr 1:205,504,596...205,532,793 		JBrowse link
G CST7 cystatin F involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:28251676) Ensembl
MGI
GO_Central		 PMID:28251676 GO_REF:0000033 GO_REF:0000107 NCBI chr20:24,949,269...24,959,928
Ensembl chr20:24,949,269...24,959,928 		JBrowse link
G DAG1 dystroglycan 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:17395644 GO_REF:0000107 RGD:11541054 NCBI chr 3:49,468,948...49,535,615
Ensembl chr 3:49,468,713...49,535,618 		JBrowse link
G DICER1 dicer 1, ribonuclease III involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:20805985) BHF-UCL
MGI		 PMID:20805985 GO_REF:0000024 NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010 		JBrowse link
G EGR2 early growth response 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,819,167 		JBrowse link
G HGF hepatocyte growth factor ISO RGD PMID:17549731 RGD:2317487 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438 		JBrowse link
G HNRNPK heterogeneous nuclear ribonucleoprotein K ISO RGD PMID:21357748 RGD:155269050 NCBI chr 9:83,968,083...83,980,615
Ensembl chr 9:83,968,083...83,980,631 		JBrowse link
G IGF1 insulin like growth factor 1 involved_in ISO (MGI:6094573|PMID:28963396) ARUK-UCL PMID:28963396 MGI:6094573 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G ITGAX integrin subunit alpha X involved_in IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:31,355,176...31,382,999
Ensembl chr16:31,355,134...31,382,999 		JBrowse link
G MAG myelin associated glycoprotein involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:35,292,161...35,313,807
Ensembl chr19:35,292,125...35,313,807 		JBrowse link
G MIR23A microRNA 23a acts_upstream_of_or_within ISO (PMID:24101522) MGI PMID:24101522 NCBI chr19:13,836,587...13,836,659
Ensembl chr19:13,836,587...13,836,659 		JBrowse link
G MYRF myelin regulatory factor involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:61,752,636...61,788,518
Ensembl chr11:61,752,636...61,788,518 		JBrowse link
G NCMAP non-compact myelin associated protein involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:24,556,087...24,609,328
Ensembl chr 1:24,556,087...24,609,328 		JBrowse link
G NGFR nerve growth factor receptor ISO RGD PMID:12424382 RGD:5508778 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008 		JBrowse link
G NRDC nardilysin convertase involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:51,789,210...51,878,727
Ensembl chr 1:51,789,191...51,878,805 		JBrowse link
G PARD3 par-3 family cell polarity regulator involved_in ISS UniProt GO_REF:0000024 NCBI chr10:34,109,561...34,815,296
Ensembl chr10:34,109,560...34,815,325 		JBrowse link
G QKI QKI, KH domain containing RNA binding involved_in ISS UniProt GO_REF:0000024 NCBI chr 6:163,414,718...163,578,592
Ensembl chr 6:163,414,000...163,578,592 		JBrowse link
G RNF10 ring finger protein 10 involved_in IEA
IBA
ISS		 Ensembl
TreeGrafter
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr12:120,534,356...120,577,588
Ensembl chr12:120,533,480...120,577,588 		JBrowse link
G S100B S100 calcium binding protein B ISO RGD PMID:25536222 RGD:12879826 NCBI chr21:46,598,604...46,605,082
Ensembl chr21:46,598,604...46,605,208 		JBrowse link
G SGMS1-AS1 SGMS1 antisense RNA 1 acts_upstream_of_or_within ISO (PMID:24101522) MGI PMID:24101522 NCBI chr10:50,624,951...50,631,636
Ensembl chr10:50,623,466...50,641,451 		JBrowse link
G SLC25A12 solute carrier family 25 member 12 ISO RGD PMID:20015484 RGD:13628737 NCBI chr 2:171,783,405...171,894,244
Ensembl chr 2:171,783,405...171,999,859 		JBrowse link
G SOX10 SRY-box transcription factor 10 involved_in ISO
IEA		 RGD
Ensembl		 PMID:25536222 GO_REF:0000107 RGD:12879826 NCBI chr22:37,972,312...37,984,555
Ensembl chr22:37,970,686...37,987,422 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in ISO (MGI:6712091|PMID:33942715) UniProt PMID:33942715 MGI:6712091 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306 		JBrowse link
G TENM4 teneurin transmembrane protein 4 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:78,652,829...79,441,030
Ensembl chr11:78,652,829...79,441,030 		JBrowse link
G TF transferrin ISO RGD PMID:16480980 RGD:1601540 NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B involved_in ISS
IEA
IBA		 ARUK-UCL
TreeGrafter
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
G TPPP tubulin polymerization promoting protein involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:659,862...700,727
Ensembl chr 5:659,862...693,352 		JBrowse link
G WASF3 WASP family member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16723544) Ensembl
MGI		 PMID:16723544 GO_REF:0000107 NCBI chr13:26,539,139...26,688,948
Ensembl chr13:26,557,683...26,688,948 		JBrowse link
G ZNF488 zinc finger protein 488 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:47,365,496...47,384,293
Ensembl chr10:47,365,496...47,384,293 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    regulation of biological process 13016
      regulation of cellular process 12447
        regulation of myelination 66
          negative regulation of myelination 11
          positive regulation of myelination 29
Path 2
Term Annotations click to browse term
  biological_process 19669
    developmental process 7610
      anatomical structure development 7020
        multicellular organism development 5632
          system development 4908
            nervous system development 3048
              ensheathment of neurons 207
                axon ensheathment 207
                  myelination 204
                    regulation of myelination 66
                      negative regulation of myelination 11
                      positive regulation of myelination 29
paths to the root