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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of myelination
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Accession:GO:0031641 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.



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regulation of myelination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 acts_upstream_of_or_within ISO (MGI:5516374|PMID:24101522) RGD PMID:24101522 MGI:5516374 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Cdh2 cadherin 2 IMP RGD PMID:11414796 RGD:1626299 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:1858008 (MGI:3849618|PMID:19515974)
GO_REF:0000107
RGD
Ensembl
PMID:19515974 GO_REF:0000107 MGI:3849618 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 IMP RGD PMID:31371763 RGD:14981598 NCBI chr 1:106,710,924...106,799,393
Ensembl chr 1:106,711,016...106,799,386
JBrowse link
G Dicer1 dicer 1 ribonuclease III acts_upstream_of_or_within ISO (MGI:4439416|PMID:20223197) RGD PMID:20223197 MGI:4439416 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4454957|PMID:20448149)
Ensembl
RGD
PMID:20448149 GO_REF:0000107 MGI:4454957 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689
JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:2149674 (MGI:3702785|PMID:17006542)
UniProt
RGD
PMID:17006542 GO_REF:0000024 MGI:3702785 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001
JBrowse link
G Kif14 kinesin family member 14 involved_in ISO (MGI:5485315|PMID:23308235), (MGI:5605219|PMID:24931760) RGD PMID:23308235 PMID:24931760 MGI:5485315 MGI:5605219 NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164
JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 involved_in ISO (PMID:28318499)
(MGI:3614587|PMID:16341215)
RGD PMID:16341215 PMID:28318499 MGI:3614587 NCBI chr 1:86,294,539...86,305,909
Ensembl chr 1:86,295,074...86,304,874
JBrowse link
G Mir219a1 microRNA 219a-1 acts_upstream_of_or_within ISO (MGI:4439416|PMID:20223197) RGD PMID:20223197 MGI:4439416 NCBI chr20:4,829,687...4,829,796
Ensembl chr20:4,829,687...4,829,796
JBrowse link
G Mtor mechanistic target of rapamycin kinase acts_upstream_of_or_within ISO (MGI:5516374|PMID:24101522) RGD PMID:24101522 MGI:5516374 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Ncmap noncompact myelin associated protein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:147,608,042...147,623,266
Ensembl chr 5:147,610,677...147,618,775
JBrowse link
G Nkx6-2 NK6 homeobox 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3521547|PMID:15601927)
UniProt
RGD
PMID:15601927 GO_REF:0000024 MGI:3521547 NCBI chr 1:194,380,149...194,383,533
Ensembl chr 1:194,381,975...194,383,515
JBrowse link
G Nsun5 NOP2/Sun RNA methyltransferase 5 involved_in ISO (MGI:6359541|PMID:31174389) RGD PMID:31174389 MGI:6359541 NCBI chr12:21,293,637...21,299,319
Ensembl chr12:21,293,645...21,299,272
JBrowse link
G Ptn pleiotrophin involved_in ISS
ISO
GO_REF:0000024
(MGI:5805301|PMID:27445335)
UniProt
RGD
PMID:27445335 GO_REF:0000024 MGI:5805301 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456
JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5805301|PMID:27445335)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:27445335 GO_REF:0000024 GO_REF:0000107 MGI:5805301 NCBI chr 4:51,397,316...51,595,220
Ensembl chr 4:51,397,601...51,595,218
JBrowse link
G Rara retinoic acid receptor, alpha IDA RGD PMID:20648638 RGD:6771320 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rarb retinoic acid receptor, beta IDA RGD PMID:20648638 RGD:6771320 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rarg retinoic acid receptor, gamma IDA RGD PMID:20648638 RGD:6771320 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177
JBrowse link
G Rxra retinoid X receptor alpha IDA RGD PMID:20648638 RGD:6771320 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Rxrb retinoid X receptor beta IDA RGD PMID:20648638 RGD:6771320 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
JBrowse link
G Rxrg retinoid X receptor gamma IDA RGD PMID:20648638 RGD:6771320 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
JBrowse link
G Sirt2 sirtuin 2 involved_in IMP
ISO
PMID:21949390
(MGI:5295137|PMID:21949390)
RGD PMID:21949390 PMID:21949390 MGI:5295137, RGD:8655533 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975
JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (MGI:4359141|PMID:19503085) RGD PMID:19503085 MGI:4359141 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
G Tenm4 teneurin transmembrane protein 4 involved_in ISO (PMID:26188006) RGD PMID:26188006 NCBI chr 1:149,895,097...151,263,315
Ensembl chr 1:150,780,381...151,259,144
JBrowse link
G Tg thyroglobulin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856829 (MGI:51594|PMID:1508304)
Ensembl
RGD
PMID:1508304 GO_REF:0000107 MGI:51594 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO UniProtKB:Q9Z0D9 (MGI:5888814|PMID:28052249) RGD PMID:28052249 MGI:5888814 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Tymp thymidine phosphorylase involved_in ISO (PMID:9924029) RGD PMID:9924029 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874
JBrowse link
G Zpr1 ZPR1 zinc finger involved_in ISO (MGI:5424069|PMID:22422766) RGD PMID:22422766 MGI:5424069 NCBI chr 8:46,564,898...46,574,719
Ensembl chr 8:46,565,146...46,574,719
JBrowse link
negative regulation of myelination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsc cathepsin C acts_upstream_of_or_within ISO MGI:5910745 (MGI:5904382|PMID:28251676) RGD PMID:28251676 MGI:5904382 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:2177666 (MGI:3583403|PMID:15911877) RGD PMID:15911877 MGI:3583403 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Fig4 FIG4 phosphoinositide 5-phosphatase acts_upstream_of_or_within ISO MGI:1924366|MGI:3716838 (MGI:5296993|PMID:22028665) RGD PMID:22028665 MGI:5296993 NCBI chr20:44,600,603...44,724,047
Ensembl chr20:44,600,603...44,723,844
JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (MGI:3583403|PMID:15911877) RGD PMID:15911877 MGI:3583403 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Jam2 junctional adhesion molecule 2 involved_in ISO (MGI:5883159|PMID:27499083) RGD PMID:27499083 MGI:5883159 NCBI chr11:23,830,820...23,880,071
Ensembl chr11:23,831,106...23,880,063
JBrowse link
G Klk8 kallikrein related-peptidase 8 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3766680|PMID:17629414)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:17629414 GO_REF:0000024 GO_REF:0000107 MGI:3766680 NCBI chr 1:94,251,803...94,258,646
Ensembl chr 1:94,251,803...94,258,646
JBrowse link
G Lpin1 lipin 1 IMP RGD PMID:21715287 RGD:38599010 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Mtmr2 myotubularin related protein 2 acts_upstream_of_or_within ISO MGI:2143585|MGI:3513454 (MGI:4352761|PMID:19587293), (MGI:5296993|PMID:22028665) RGD PMID:19587293 PMID:22028665 MGI:4352761 MGI:5296993 NCBI chr 8:10,617,993...10,670,724
Ensembl chr 8:10,617,993...10,668,172
JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO (MGI:4454957|PMID:20448149) RGD PMID:20448149 MGI:4454957 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Tmem98 transmembrane protein 98 involved_in ISS
ISO
GO_REF:0000024
(MGI:6258499|PMID:30249802)
UniProt
RGD
PMID:30249802 GO_REF:0000024 MGI:6258499 NCBI chr10:65,796,173...65,807,082
Ensembl chr10:65,796,145...65,807,079
JBrowse link
G Tnf tumor necrosis factor IMP RGD PMID:23982745 RGD:10450590 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in IBA
ISO
PMID:21873635
(PMID:21725297)
RGD PMID:21725297 PMID:21873635 RGD:13792537 NCBI chr 9:17,879,156...17,954,085
Ensembl chr 9:17,879,156...17,954,085
JBrowse link
positive regulation of myelination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst7 cystatin F involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5910746 (MGI:5904382|PMID:28251676)
RGD PMID:28251676 PMID:21873635 MGI:5904382, RGD:13792537 NCBI chr 3:139,396,830...139,405,557
Ensembl chr 3:139,396,850...139,405,557
JBrowse link
G Dag1 dystroglycan 1 IMP RGD PMID:17395644 RGD:11541054 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325
JBrowse link
G Dicer1 dicer 1 ribonuclease III involved_in
acts_upstream_of_or_within
ISO (MGI:4454581|PMID:20463238)
MGI:3589208 (MGI:4830414|PMID:20805985)
RGD PMID:20463238 PMID:20805985 MGI:4454581 MGI:4830414 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G Egr2 early growth response 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:69122|PMID:7935840)
UniProt
RGD
PMID:7935840 GO_REF:0000024 MGI:69122 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Hgf hepatocyte growth factor IDA RGD PMID:17549731 RGD:2317487 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO (MGI:6094573|PMID:28963396) RGD PMID:28963396 MGI:6094573 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Itgax integrin subunit alpha X involved_in ISO (MGI:6094573|PMID:28963396) RGD PMID:28963396 MGI:6094573 NCBI chr 1:182,709,653...182,740,709
Ensembl chr 1:182,719,609...182,740,698
JBrowse link
G Mag myelin-associated glycoprotein involved_in ISO (MGI:1352580|PMID:10625334) RGD PMID:10625334 MGI:1352580 NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656
JBrowse link
G Mir23a microRNA 23a acts_upstream_of_or_within ISO (MGI:5516374|PMID:24101522) RGD PMID:24101522 MGI:5516374 NCBI chr19:23,954,997...23,955,071
Ensembl chr19:23,954,997...23,955,071
JBrowse link
G Myrf myelin regulatory factor involved_in ISO (MGI:3850982|PMID:19596243), (MGI:6258499|PMID:30249802) RGD PMID:19596243 PMID:30249802 MGI:3850982 MGI:6258499 NCBI chr 1:206,854,175...206,886,276
Ensembl chr 1:206,854,175...206,886,157
JBrowse link
G Ncmap noncompact myelin associated protein involved_in IDA PMID:18650334 UniProt PMID:18650334 RGD:8554263 NCBI chr 5:147,608,042...147,623,266
Ensembl chr 5:147,610,677...147,618,775
JBrowse link
G Ngfr nerve growth factor receptor IMP RGD PMID:12424382 RGD:5508778 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Nrdc nardilysin convertase involved_in ISS
ISO
GO_REF:0000024
(MGI:4414693|PMID:19935654)
UniProt
RGD
PMID:19935654 GO_REF:0000024 MGI:4414693 NCBI chr 5:123,755,807...123,818,910
Ensembl chr 5:123,755,806...123,818,595
JBrowse link
G Nrg1 neuregulin 1 acts_upstream_of_or_within
NOT|acts_upstream_of_or_within
ISO MGI:1928489 (MGI:3042336|PMID:15044753)
MGI:1928831 (MGI:3590355|PMID:16129398), (MGI:4420197|PMID:18080294)
RGD PMID:15044753 PMID:16129398 PMID:18080294 MGI:3042336 MGI:3590355 MGI:4420197 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Pard3 par-3 family cell polarity regulator involved_in ISS
ISO
GO_REF:0000024
(MGI:5295137|PMID:21949390)
UniProt
RGD
PMID:21949390 GO_REF:0000024 MGI:5295137 NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778
JBrowse link
G Rnf10 ring finger protein 10 involved_in IMP
IBA
PMID:18941509
PMID:21873635
UniProt
GO_Central
PMID:18941509 PMID:21873635 RGD:8553607, RGD:13792537 NCBI chr12:41,341,717...41,375,505
Ensembl chr12:41,341,717...41,375,504
JBrowse link
G S100b S100 calcium binding protein B IMP RGD PMID:25536222 RGD:12879826 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
JBrowse link
G Slc25a12 solute carrier family 25 member 12 IMP RGD PMID:20015484 RGD:13628737 NCBI chr 3:56,098,080...56,192,188
Ensembl chr 3:56,097,269...56,192,100
JBrowse link
G Sox10 SRY-box transcription factor 10 IMP RGD PMID:25536222 RGD:12879826 NCBI chr 7:110,725,274...110,735,544
Ensembl chr 7:110,725,274...110,735,544
JBrowse link
G Tenm4 teneurin transmembrane protein 4 involved_in ISO (MGI:5437806|PMID:22915103) RGD PMID:22915103 MGI:5437806 NCBI chr 1:149,895,097...151,263,315
Ensembl chr 1:150,780,381...151,259,144
JBrowse link
G Tf transferrin IDA RGD PMID:16480980 RGD:1601540 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in IBA
ISO
PMID:21873635
(MGI:5775216|PMID:27147664)
RGD PMID:27147664 PMID:21873635 MGI:5775216, RGD:13792537 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Tppp tubulin polymerization promoting protein involved_in IMP
ISO
PMID:19606501
(MGI:6368053|PMID:31522887)
RGD PMID:31522887 PMID:19606501 MGI:6368053, RGD:14995315 NCBI chr 1:29,257,111...29,281,134
Ensembl chr 1:29,261,255...29,281,134
JBrowse link
G Wasf3 WASP family member 3 acts_upstream_of_or_within ISO MGI:2663235 (MGI:3625634|PMID:16723544) RGD PMID:16723544 MGI:3625634 NCBI chr12:8,563,805...8,660,799
Ensembl chr12:8,562,062...8,660,751
JBrowse link
G Zfp488 zinc finger protein 488 involved_in ISO (MGI:6189284|PMID:22355521) RGD PMID:22355521 MGI:6189284 NCBI chr16:9,282,394...9,294,129
Ensembl chr16:9,283,043...9,293,671
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20099
    regulation of biological process 13160
      regulation of cellular process 12438
        regulation of myelination 62
          negative regulation of myelination 12
          positive regulation of myelination 25
Path 2
Term Annotations click to browse term
  biological_process 20099
    developmental process 7010
      anatomical structure development 6447
        multicellular organism development 5225
          system development 4486
            nervous system development 2804
              ensheathment of neurons 180
                axon ensheathment 180
                  myelination 178
                    regulation of myelination 62
                      negative regulation of myelination 12
                      positive regulation of myelination 25
paths to the root