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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of myelination
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Accession:GO:0031641 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.


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regulation of myelination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 acts_upstream_of_or_within ISO (MGI:5516374|PMID:24101522) RGD PMID:24101522 MGI:5516374 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Cdh2 cadherin 2 IMP RGD PMID:11414796 RGD:1626299 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1858008 (MGI:3849618|PMID:19515974)
Ensembl
RGD
PMID:19515974 GO_REF:0000107 MGI:3849618 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 IMP RGD PMID:31371763 RGD:14981598 NCBI chr 1:114,258,773...114,347,138
Ensembl chr 1:114,258,719...114,347,137
JBrowse link
G Dicer1 dicer 1 ribonuclease III acts_upstream_of_or_within ISO (MGI:4439416|PMID:20223197) RGD PMID:20223197 MGI:4439416 NCBI chr 6:128,388,084...128,453,234
Ensembl chr 6:128,388,053...128,434,183
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4454957|PMID:20448149)
Ensembl
RGD
PMID:20448149 GO_REF:0000107 MGI:4454957 NCBI chr11:72,164,566...72,378,895
Ensembl chr11:72,163,749...72,378,895
JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:2149674 (MGI:3702785|PMID:17006542)
UniProt
RGD
PMID:17006542 GO_REF:0000024 MGI:3702785 NCBI chr 5:172,364,421...172,365,188
Ensembl chr 5:172,364,421...172,365,188
JBrowse link
G Kif14 kinesin family member 14 involved_in ISO (MGI:5485315|PMID:23308235), (MGI:5605219|PMID:24931760) RGD PMID:23308235 PMID:24931760 MGI:5485315 MGI:5605219 NCBI chr13:53,350,073...53,421,992
Ensembl chr13:53,351,717...53,420,111
JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 involved_in ISO (PMID:28318499)
(MGI:3614587|PMID:16341215)
RGD PMID:16341215 PMID:28318499 MGI:3614587 NCBI chr 1:89,491,588...89,502,939
Ensembl chr 1:89,491,654...89,502,974
JBrowse link
G Mir219a1 microRNA 219a-1 acts_upstream_of_or_within ISO (MGI:4439416|PMID:20223197) RGD PMID:20223197 MGI:4439416 NCBI chr20:3,816,158...3,816,267
Ensembl chr20:3,816,158...3,816,267
JBrowse link
G Mtor mechanistic target of rapamycin kinase acts_upstream_of_or_within ISO (MGI:5516374|PMID:24101522) RGD PMID:24101522 MGI:5516374 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Ncmap noncompact myelin associated protein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:153,729,250...153,737,161
Ensembl chr 5:153,729,250...153,737,161
JBrowse link
G Nkx6-2 NK6 homeobox 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3521547|PMID:15601927)
UniProt
RGD
PMID:15601927 GO_REF:0000024 MGI:3521547 NCBI chr 1:211,922,389...211,923,929
Ensembl chr 1:211,922,389...211,923,929
JBrowse link
G Nsun5 NOP2/Sun RNA methyltransferase 5 involved_in ISO (MGI:6359541|PMID:31174389) RGD PMID:31174389 MGI:6359541 NCBI chr12:24,341,940...24,346,900
Ensembl chr12:24,341,928...24,346,918
JBrowse link
G Ptn pleiotrophin involved_in ISS
ISO
GO_REF:0000024
(MGI:5805301|PMID:27445335)
UniProt
RGD
PMID:27445335 GO_REF:0000024 MGI:5805301 NCBI chr 4:64,239,156...64,330,996
Ensembl chr 4:64,239,158...64,330,996
JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5805301|PMID:27445335)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:27445335 GO_REF:0000024 GO_REF:0000107 MGI:5805301 NCBI chr 4:49,941,046...50,140,764
Ensembl chr 4:49,941,304...50,140,762
JBrowse link
G Rara retinoic acid receptor, alpha IDA RGD PMID:20648638 RGD:6771320 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rarb retinoic acid receptor, beta IDA RGD PMID:20648638 RGD:6771320 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
JBrowse link
G Rarg retinoic acid receptor, gamma IDA RGD PMID:20648638 RGD:6771320 NCBI chr 7:143,840,739...143,863,206
Ensembl chr 7:143,839,980...143,863,186
JBrowse link
G Rxra retinoid X receptor alpha IDA RGD PMID:20648638 RGD:6771320 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Rxrb retinoid X receptor beta IDA RGD PMID:20648638 RGD:6771320 NCBI chr20:3,822,673...3,829,138
Ensembl chr20:3,823,042...3,829,140
JBrowse link
G Rxrg retinoid X receptor gamma IDA RGD PMID:20648638 RGD:6771320 NCBI chr13:85,818,473...85,868,555
Ensembl chr13:85,818,427...85,868,552
JBrowse link
G Sirt2 sirtuin 2 involved_in IEA
ISO
IMP
GO_REF:0000107
(MGI:5295137|PMID:21949390)
Ensembl
RGD
PMID:21949390, PMID:21949390 GO_REF:0000107 MGI:5295137, RGD:8655533 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952
JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (MGI:4359141|PMID:19503085) RGD PMID:19503085 MGI:4359141 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
G Tenm4 teneurin transmembrane protein 4 involved_in ISO (PMID:26188006) RGD PMID:26188006 NCBI chr 1:161,183,858...161,885,094
Ensembl chr 1:161,401,527...161,880,923
JBrowse link
G Tg thyroglobulin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856829 (MGI:51594|PMID:1508304)
Ensembl
RGD
PMID:1508304 GO_REF:0000107 MGI:51594 NCBI chr 7:107,467,260...107,652,897
Ensembl chr 7:107,467,260...107,652,899
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO UniProtKB:Q9Z0D9 (MGI:5888814|PMID:28052249) RGD PMID:28052249 MGI:5888814 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Tymp thymidine phosphorylase involved_in ISO (PMID:9924029) RGD PMID:9924029 NCBI chr 7:130,342,481...130,347,845
Ensembl chr 7:130,342,483...130,347,587
JBrowse link
G Zpr1 ZPR1 zinc finger involved_in ISO (MGI:5424069|PMID:22422766) RGD PMID:22422766 MGI:5424069 NCBI chr 8:50,563,047...50,572,621
Ensembl chr 8:50,563,047...50,572,621
JBrowse link
negative regulation of myelination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsc cathepsin C acts_upstream_of_or_within ISO MGI:5910745 (MGI:5904382|PMID:28251676) RGD PMID:28251676 MGI:5904382 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:2177666 (MGI:3583403|PMID:15911877) RGD PMID:15911877 MGI:3583403 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Fig4 FIG4 phosphoinositide 5-phosphatase acts_upstream_of_or_within ISO MGI:1924366|MGI:3716838 (MGI:5296993|PMID:22028665) RGD PMID:22028665 MGI:5296993 NCBI chr20:45,922,806...46,044,754
Ensembl chr20:45,922,806...46,044,738
JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (MGI:3583403|PMID:15911877) RGD PMID:15911877 MGI:3583403 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Jam2 junctional adhesion molecule 2 involved_in ISO (MGI:5883159|PMID:27499083) RGD PMID:27499083 MGI:5883159 NCBI chr11:24,235,310...24,285,279
Ensembl chr11:24,266,345...24,285,275
JBrowse link
G Klk8 kallikrein related-peptidase 8 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3766680|PMID:17629414)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:17629414 GO_REF:0000024 GO_REF:0000107 MGI:3766680 NCBI chr 1:99,735,168...99,742,011
Ensembl chr 1:99,734,993...99,742,009
JBrowse link
G Lpin1 lipin 1 IDA RGD PMID:21715287 RGD:38599010 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G Mtmr2 myotubularin related protein 2 acts_upstream_of_or_within ISO MGI:2143585|MGI:3513454 (MGI:4352761|PMID:19587293), (MGI:5296993|PMID:22028665) RGD PMID:19587293 PMID:22028665 MGI:4352761 MGI:5296993 NCBI chr 8:12,283,471...12,334,014
Ensembl chr 8:12,284,528...12,333,316
JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO (MGI:4454957|PMID:20448149) RGD PMID:20448149 MGI:4454957 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Tmem98 transmembrane protein 98 involved_in ISS
ISO
GO_REF:0000024
(MGI:6258499|PMID:30249802)
UniProt
RGD
PMID:30249802 GO_REF:0000024 MGI:6258499 NCBI chr10:68,173,380...68,184,289
Ensembl chr10:68,173,369...68,184,320
JBrowse link
G Tnf tumor necrosis factor IMP RGD PMID:23982745 RGD:10450590 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in IBA
ISO
PMID:21873635
(PMID:21725297)
RGD PMID:21725297, PMID:21873635 RGD:13792537 NCBI chr 9:20,546,159...20,621,051
Ensembl chr 9:20,546,159...20,621,051
JBrowse link
positive regulation of myelination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst7 cystatin F involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5910746 (MGI:5904382|PMID:28251676)
RGD PMID:28251676, PMID:21873635 MGI:5904382, RGD:13792537 NCBI chr 3:146,363,913...146,373,365
Ensembl chr 3:146,365,092...146,373,365
JBrowse link
G Dag1 dystroglycan 1 IMP RGD PMID:17395644 RGD:11541054 NCBI chr 8:116,980,501...116,993,182
Ensembl chr 8:116,980,497...116,993,193
JBrowse link
G Dicer1 dicer 1 ribonuclease III involved_in
acts_upstream_of_or_within
ISO (MGI:4454581|PMID:20463238)
MGI:3589208 (MGI:4830414|PMID:20805985)
RGD PMID:20463238 PMID:20805985 MGI:4454581 MGI:4830414 NCBI chr 6:128,388,084...128,453,234
Ensembl chr 6:128,388,053...128,434,183
JBrowse link
G Egr2 early growth response 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:69122|PMID:7935840)
UniProt
RGD
PMID:7935840 GO_REF:0000024 MGI:69122 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Hgf hepatocyte growth factor IDA RGD PMID:17549731 RGD:2317487 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO (MGI:6094573|PMID:28963396) RGD PMID:28963396 MGI:6094573 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Itgax integrin subunit alpha X involved_in ISO (MGI:6094573|PMID:28963396) RGD PMID:28963396 MGI:6094573 NCBI chr 1:199,555,560...199,576,948
Ensembl chr 1:199,555,722...199,576,932
JBrowse link
G Mag myelin-associated glycoprotein involved_in ISO (MGI:1352580|PMID:10625334) RGD PMID:10625334 MGI:1352580 NCBI chr 1:89,345,325...89,360,905
Ensembl chr 1:89,345,429...89,360,733
JBrowse link
G Mir23a microRNA 23a acts_upstream_of_or_within ISO (MGI:5516374|PMID:24101522) RGD PMID:24101522 MGI:5516374 NCBI chr19:25,318,582...25,318,656
Ensembl chr19:25,318,582...25,318,656
JBrowse link
G Myrf myelin regulatory factor involved_in ISO (MGI:3850982|PMID:19596243), (MGI:6258499|PMID:30249802) RGD PMID:19596243 PMID:30249802 MGI:3850982 MGI:6258499 NCBI chr 1:226,260,558...226,292,650
Ensembl chr 1:226,260,558...226,292,480
JBrowse link
G Ncmap noncompact myelin associated protein involved_in IDA PMID:18650334 UniProt PMID:18650334 RGD:8554263 NCBI chr 5:153,729,250...153,737,161
Ensembl chr 5:153,729,250...153,737,161
JBrowse link
G Ngfr nerve growth factor receptor IMP RGD PMID:12424382 RGD:5508778 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nrg1 neuregulin 1 acts_upstream_of_or_within
NOT|acts_upstream_of_or_within
ISO MGI:1928489 (MGI:3042336|PMID:15044753)
MGI:1928831 (MGI:3590355|PMID:16129398), (MGI:4420197|PMID:18080294)
RGD PMID:15044753 PMID:16129398 PMID:18080294 MGI:3042336 MGI:3590355 MGI:4420197 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Pard3 par-3 family cell polarity regulator involved_in ISS
ISO
GO_REF:0000024
(MGI:5295137|PMID:21949390)
UniProt
RGD
PMID:21949390 GO_REF:0000024 MGI:5295137 NCBI chr19:60,017,746...60,580,628
Ensembl chr19:60,017,746...60,580,651
JBrowse link
G Rnf10 ring finger protein 10 involved_in IMP
IBA
PMID:18941509
PMID:21873635
UniProt
GO_Central
PMID:18941509, PMID:21873635 RGD:8553607, RGD:13792537 NCBI chr12:47,103,313...47,137,096
Ensembl chr12:47,103,314...47,138,128
JBrowse link
G S100b S100 calcium binding protein B IMP RGD PMID:25536222 RGD:12879826 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G Slc25a12 solute carrier family 25 member 12 IMP RGD PMID:20015484 RGD:13628737 NCBI chr 3:57,881,951...57,998,214
Ensembl chr 3:57,882,370...57,957,346
JBrowse link
G Sox10 SRY-box transcription factor 10 IMP RGD PMID:25536222 RGD:12879826 NCBI chr 7:120,393,238...120,403,523
Ensembl chr 7:120,393,254...120,403,523
JBrowse link
G Tenm4 teneurin transmembrane protein 4 involved_in ISO (MGI:5437806|PMID:22915103) RGD PMID:22915103 MGI:5437806 NCBI chr 1:161,183,858...161,885,094
Ensembl chr 1:161,401,527...161,880,923
JBrowse link
G Tf transferrin IDA RGD PMID:16480980 RGD:1601540 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in IBA
ISO
PMID:21873635
(MGI:5775216|PMID:27147664)
RGD PMID:27147664, PMID:21873635 MGI:5775216, RGD:13792537 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Tppp tubulin polymerization promoting protein involved_in IMP
ISO
PMID:19606501
(MGI:6368053|PMID:31522887)
RGD PMID:31522887, PMID:19606501 MGI:6368053, RGD:14995315 NCBI chr 1:31,866,755...31,890,778
Ensembl chr 1:31,870,899...31,890,778
JBrowse link
G Wasf3 WASP family member 3 acts_upstream_of_or_within ISO MGI:2663235 (MGI:3625634|PMID:16723544) RGD PMID:16723544 MGI:3625634 NCBI chr12:10,297,896...10,391,014
Ensembl chr12:10,298,555...10,391,270
JBrowse link
G Zfp488 zinc finger protein 488 involved_in ISO (MGI:6189284|PMID:22355521) RGD PMID:22355521 MGI:6189284 NCBI chr16:10,292,964...10,304,794
Ensembl chr16:10,294,931...10,296,341
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19638
    regulation of biological process 12829
      regulation of cellular process 12327
        regulation of myelination 61
          negative regulation of myelination 12
          positive regulation of myelination 24
Path 2
Term Annotations click to browse term
  biological_process 19638
    developmental process 6777
      anatomical structure development 6250
        multicellular organism development 5734
          system development 5280
            nervous system development 2717
              ensheathment of neurons 175
                axon ensheathment 175
                  myelination 173
                    regulation of myelination 61
                      negative regulation of myelination 12
                      positive regulation of myelination 24
paths to the root