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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of myelination
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Accession:GO:0031641 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.


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regulation of myelination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:24101522)		 Ensembl
RGD		 PMID:24101522 GO_REF:0000107 NCBI chr 6:137,534,810...137,555,131 JBrowse link
G Cdh2 cadherin 2 IMP RGD PMID:11414796 RGD:1626299 NCBI chr18:8,051,097...8,265,288 JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1858008 (PMID:19515974)		 Ensembl
RGD		 PMID:19515974 GO_REF:0000107 NCBI chr 8:129,517,576...129,544,661 JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 IMP RGD PMID:31371763 RGD:14981598 NCBI chr 1:115,842,754...115,935,163 JBrowse link
G Dicer1 dicer 1 ribonuclease III acts_upstream_of_or_within ISO (PMID:20223197) RGD PMID:20223197 NCBI chr 6:123,627,529...123,692,278 JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:20448149)		 Ensembl
RGD		 PMID:20448149 GO_REF:0000107 NCBI chr11:82,416,853...82,607,797 JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:2149674 (PMID:17006542)		 UniProt
RGD		 PMID:17006542 GO_REF:0000024 NCBI chr 5:170,804,511...170,807,988 JBrowse link
G Kif14 kinesin family member 14 involved_in ISO (PMID:23308235), (PMID:24931760) RGD PMID:23308235 PMID:24931760 NCBI chr13:50,478,646...50,542,256 JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 involved_in ISO (PMID:28318499)
(PMID:16341215)		 RGD PMID:16341215 PMID:28318499 NCBI chr 1:86,294,539...86,305,909 JBrowse link
G Mir219a1 microRNA 219a-1 acts_upstream_of_or_within ISO (PMID:20223197) RGD PMID:20223197 NCBI chr20:4,829,687...4,829,796 JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:24101522)		 Ensembl
RGD		 PMID:24101522 GO_REF:0000107 NCBI chr 5:164,167,985...164,277,438 JBrowse link
G Ncmap noncompact myelin associated protein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:147,608,042...147,623,266 JBrowse link
G Nkx6-2 NK6 homeobox 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:194,380,149...194,383,533 JBrowse link
G Nsun5 NOP2/Sun RNA methyltransferase 5 involved_in ISO (PMID:31174389) RGD PMID:31174389 NCBI chr12:21,293,637...21,299,319 JBrowse link
G Ptn pleiotrophin involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:27445335)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:27445335 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:66,260,764...66,342,614 JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:27445335)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:27445335 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:51,397,316...51,595,220 JBrowse link
G Rara retinoic acid receptor, alpha IDA RGD PMID:20648638 RGD:6771320 NCBI chr10:83,883,490...83,928,932 JBrowse link
G Rarb retinoic acid receptor, beta IDA RGD PMID:20648638 RGD:6771320 NCBI chr15:10,837,252...11,482,037 JBrowse link
G Rarg retinoic acid receptor, gamma IDA RGD PMID:20648638 RGD:6771320 NCBI chr 7:133,367,833...133,390,301 JBrowse link
G Rxra retinoid X receptor alpha IDA RGD PMID:20648638 RGD:6771320 NCBI chr 3:31,387,892...31,474,415 JBrowse link
G Rxrb retinoid X receptor beta IDA RGD PMID:20648638 RGD:6771320 NCBI chr20:4,816,813...4,823,267 JBrowse link
G Rxrg retinoid X receptor gamma IDA RGD PMID:20648638 RGD:6771320 NCBI chr13:82,276,330...82,318,097 JBrowse link
G Sirt2 sirtuin 2 involved_in IMP
ISO
IEA		 PMID:21949390
(PMID:21949390)
GO_REF:0000107		 RGD
Ensembl		 PMID:21949390 PMID:21949390 GO_REF:0000107, RGD:8655533 NCBI chr 1:93,181,472...93,204,499 JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (PMID:19503085) RGD PMID:19503085 NCBI chr 1:264,791,335...264,984,225 JBrowse link
G Tenm4 teneurin transmembrane protein 4 involved_in ISO (PMID:26188006) RGD PMID:26188006 NCBI chr 1:149,895,097...151,263,315 JBrowse link
G Tg thyroglobulin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856829 (PMID:1508304)		 Ensembl
RGD		 PMID:1508304 GO_REF:0000107 NCBI chr 7:98,418,293...98,603,210 JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO UniProtKB:Q9Z0D9 (PMID:28052249) RGD PMID:28052249 NCBI chr 5:157,070,642...157,104,216 JBrowse link
G Tymp thymidine phosphorylase involved_in ISO (PMID:9924029) RGD PMID:9924029 NCBI chr 7:122,318,396...122,323,716 JBrowse link
G Zpr1 ZPR1 zinc finger involved_in ISO (PMID:22422766) RGD PMID:22422766 NCBI chr 8:46,564,898...46,574,719 JBrowse link
negative regulation of myelination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsc cathepsin C acts_upstream_of_or_within ISO MGI:5910745 (PMID:28251676) RGD PMID:28251676 NCBI chr 1:142,028,386...142,059,841 JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:2177666 (PMID:15911877) RGD PMID:15911877 NCBI chr 4:104,363,838...104,425,271 JBrowse link
G Fig4 FIG4 phosphoinositide 5-phosphatase acts_upstream_of_or_within ISO MGI:1924366|MGI:3716838 (PMID:22028665) RGD PMID:22028665 NCBI chr20:44,600,603...44,724,047 JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:15911877) RGD PMID:15911877 NCBI chr 7:55,789,180...55,793,216 JBrowse link
G Jam2 junctional adhesion molecule 2 involved_in ISO (PMID:27499083) RGD PMID:27499083 NCBI chr11:37,316,287...37,366,517 JBrowse link
G Lpin1 lipin 1 IMP RGD PMID:21715287 RGD:38599010 NCBI chr 6:45,039,110...45,145,845 JBrowse link
G Mtmr2 myotubularin related protein 2 acts_upstream_of_or_within ISO MGI:2143585|MGI:3513454 (PMID:19587293), (PMID:22028665) RGD PMID:19587293 PMID:22028665 NCBI chr 8:10,617,993...10,670,724 JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO (PMID:20448149) RGD PMID:20448149 NCBI chr 1:240,043,707...240,110,330 JBrowse link
G Tmem98 transmembrane protein 98 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:30249802)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:30249802 GO_REF:0000024 GO_REF:0000107 NCBI chr10:65,796,173...65,807,082 JBrowse link
G Tnf tumor necrosis factor IMP RGD PMID:23982745 RGD:10450590 NCBI chr20:3,626,685...3,629,303 JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in ISO
IBA		 (PMID:21725297)
GO_REF:0000033		 RGD
GO_Central		 PMID:21725297 GO_REF:0000033 NCBI chr 9:17,879,156...17,954,085 JBrowse link
positive regulation of myelination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk18 cyclin-dependent kinase 18 involved_in IEA
ISO		 GO_REF:0000107
(PMID:31028571)		 Ensembl
RGD		 PMID:31028571 GO_REF:0000107 NCBI chr13:46,107,763...46,140,705 JBrowse link
G Cst7 cystatin F involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:5910746 (PMID:28251676)		 GO_Central
RGD		 PMID:28251676 GO_REF:0000033 NCBI chr 3:139,396,830...139,405,557 JBrowse link
G Dag1 dystroglycan 1 IMP RGD PMID:17395644 RGD:11541054 NCBI chr 8:117,769,517...117,834,347 JBrowse link
G Dicer1 dicer 1 ribonuclease III acts_upstream_of_or_within
involved_in		 ISO MGI:3589208 (PMID:20805985)
(PMID:20463238), (PMID:20805985)		 RGD PMID:20463238 PMID:20805985 NCBI chr 6:123,627,529...123,692,278 JBrowse link
G Egr2 early growth response 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:7935840)		 UniProt
RGD		 PMID:7935840 GO_REF:0000024 NCBI chr20:21,051,270...21,056,322 JBrowse link
G Hgf hepatocyte growth factor IDA RGD PMID:17549731 RGD:2317487 NCBI chr 4:19,628,902...19,700,467 JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K IMP RGD PMID:21357748 RGD:155269050 NCBI chr17:6,269,302...6,280,429 JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO (PMID:28963396) RGD PMID:28963396 NCBI chr 7:24,169,608...24,249,446 JBrowse link
G Itgax integrin subunit alpha X involved_in ISO (PMID:28963396) RGD PMID:28963396 NCBI chr 1:182,709,653...182,740,709 JBrowse link
G Mag myelin-associated glycoprotein involved_in ISO (PMID:10625334) RGD PMID:10625334 NCBI chr 1:86,148,227...86,163,726 JBrowse link
G Mir23a microRNA 23a acts_upstream_of_or_within ISO (PMID:24101522) RGD PMID:24101522 NCBI chr19:23,954,997...23,955,071 JBrowse link
G Myrf myelin regulatory factor involved_in ISO (PMID:19596243), (PMID:30249802) RGD PMID:19596243 PMID:30249802 NCBI chr 1:206,854,175...206,886,276 JBrowse link
G Ncmap noncompact myelin associated protein involved_in IDA PMID:18650334 UniProt PMID:18650334 RGD:8554263 NCBI chr 5:147,608,042...147,623,266 JBrowse link
G Ngfr nerve growth factor receptor IMP RGD PMID:12424382 RGD:5508778 NCBI chr10:81,012,077...81,030,305 JBrowse link
G Nrdc nardilysin convertase involved_in ISS
ISO		 GO_REF:0000024
(PMID:19935654)		 UniProt
RGD		 PMID:19935654 GO_REF:0000024 NCBI chr 5:123,755,807...123,818,910 JBrowse link
G Pard3 par-3 family cell polarity regulator involved_in ISS
ISO		 GO_REF:0000024
(PMID:21949390)		 UniProt
RGD		 PMID:21949390 GO_REF:0000024 NCBI chr19:55,080,282...55,630,111 JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in ISO (PMID:33942715) RGD PMID:33942715 NCBI chr 1:50,387,716...50,501,568 JBrowse link
G Rnf10 ring finger protein 10 involved_in IMP
IBA		 PMID:18941509
GO_REF:0000033		 GO_Central PMID:18941509 GO_REF:0000033, RGD:8553607 NCBI chr12:41,341,708...41,375,505 JBrowse link
G S100b S100 calcium binding protein B IMP RGD PMID:25536222 RGD:12879826 NCBI chr20:12,372,345...12,381,159 JBrowse link
G Slc25a12 solute carrier family 25 member 12 IMP RGD PMID:20015484 RGD:13628737 NCBI chr 3:56,097,166...56,191,841 JBrowse link
G Sox10 SRY-box transcription factor 10 IMP RGD PMID:25536222 RGD:12879826 NCBI chr 7:110,725,274...110,734,651 JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in ISO (PMID:33942715) RGD PMID:33942715 NCBI chr 7:115,542,774...115,600,945 JBrowse link
G Tenm4 teneurin transmembrane protein 4 involved_in ISO (PMID:22915103) RGD PMID:22915103 NCBI chr 1:149,895,097...151,263,315 JBrowse link
G Tf transferrin IDA RGD PMID:16480980 RGD:1601540 NCBI chr 8:103,789,780...103,816,487 JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in IBA
ISO		 GO_REF:0000033
(PMID:27147664)		 GO_Central
RGD		 PMID:27147664 GO_REF:0000033 NCBI chr 5:157,070,642...157,104,216 JBrowse link
G Tppp tubulin polymerization promoting protein involved_in IMP
IEA
ISO		 PMID:19606501
GO_REF:0000107
(PMID:31522887)		 Ensembl
RGD		 PMID:31522887 PMID:19606501 GO_REF:0000107, RGD:14995315 NCBI chr 1:29,257,111...29,281,134 JBrowse link
G Wasf3 WASP family member 3 acts_upstream_of_or_within ISO MGI:2663235 (PMID:16723544) RGD PMID:16723544 NCBI chr12:8,563,805...8,660,799 JBrowse link
G Zfp488 zinc finger protein 488 involved_in ISO (PMID:22355521) RGD PMID:22355521 NCBI chr16:9,289,286...9,299,928 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    regulation of biological process 13375
      regulation of cellular process 13013
        regulation of myelination 64
          negative regulation of myelination 11
          positive regulation of myelination 28
Path 2
Term Annotations click to browse term
  biological_process 20534
    developmental process 7107
      anatomical structure development 6609
        multicellular organism development 5329
          system development 4611
            nervous system development 2862
              ensheathment of neurons 199
                axon ensheathment 199
                  myelination 197
                    regulation of myelination 64
                      negative regulation of myelination 11
                      positive regulation of myelination 28
paths to the root