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ONTOLOGY REPORT - ANNOTATIONS


Term:synaptic vesicle fusion to presynaptic active zone membrane
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Accession:GO:0031629 term browser browse the term
Definition:Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft.
Synonyms:exact_synonym: synaptic vesicle fusion to pre-synaptic membrane;   synaptic vesicle fusion to presynaptic membrane
 broad_synonym: synaptic vesicle fusion


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synaptic vesicle fusion to presynaptic active zone membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prrt2 proline rich transmembrane protein 2 involved_in ISO (MGI:5792766|PMID:27052163) UniProt PMID:27052163 MGI:5792766 NCBI chrNW_004936501:12,660,181...12,663,788 JBrowse link
G Snapin SNAP associated protein acts_upstream_of_or_within ISO (MGI:4430710|PMID:19217378) MGI PMID:19217378 MGI:4430710 NCBI chrNW_004936580:3,449,585...3,464,709 JBrowse link
G Stx1a syntaxin 1A involved_in ISO PMID:18703708 SynGO PMID:18703708 RGD:11535099 NCBI chrNW_004936543:2,909,560...2,918,175 JBrowse link
G Stx1b syntaxin 1B involved_in ISO (MGI:5603022|PMID:24587181)
(MGI:3803800|PMID:18703708), (MGI:5603022|PMID:24587181)
SynGO PMID:18703708 PMID:24587181 MGI:3803800 MGI:5603022 NCBI chrNW_004936501:13,370,678...13,378,933 JBrowse link
calcium-dependent activation of synaptic vesicle fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prrt2 proline rich transmembrane protein 2 involved_in ISO (MGI:5792766|PMID:27052163) SynGO PMID:27052163 MGI:5792766 NCBI chrNW_004936501:12,660,181...12,663,788 JBrowse link
G Syt1 synaptotagmin 1 involved_in ISO (MGI:69538|PMID:7954835) SynGO PMID:7954835 MGI:69538 NCBI chrNW_004936698:65,210...575,538 JBrowse link
G Syt2 synaptotagmin 2 involved_in ISO (MGI:3695515|PMID:17192432) SynGO PMID:17192432 MGI:3695515 NCBI chrNW_004936567:1,941,651...1,984,422 JBrowse link
G Syt7 synaptotagmin 7 involved_in ISO (MGI:5554634|PMID:24267651) SynGO PMID:24267651 MGI:5554634 NCBI chrNW_004936581:1,516,199...1,557,992 JBrowse link
G Syt9 synaptotagmin 9 involved_in ISO (MGI:3714434|PMID:17521570) SynGO PMID:17521570 MGI:3714434 NCBI chrNW_004936841:542,211...706,272 JBrowse link
regulation of synaptic vesicle fusion to presynaptic active zone membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cplx1 complexin 1 involved_in ISO (MGI:2679622|PMID:11163241) SynGO PMID:11163241 MGI:2679622 NCBI chrNW_004936477:22,315,827...22,338,488 JBrowse link
G Cplx2 complexin 2 involved_in ISO (MGI:2679622|PMID:11163241) SynGO PMID:11163241 MGI:2679622 NCBI chrNW_004936597:276,540...356,822 JBrowse link
G Cplx3 complexin 3 involved_in ISO (MGI:5818105|PMID:27239031) SynGO PMID:27239031 MGI:5818105 NCBI chrNW_004936471:33,798,523...33,803,045 JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 acts_upstream_of_or_within ISO (MGI:2449894|PMID:12533602) MGI PMID:12533602 MGI:2449894 NCBI chrNW_004936706:410,806...469,000 JBrowse link
G Rab3a RAB3A, member RAS oncogene family involved_in
acts_upstream_of_or_within
ISO (MGI:3653150|PMID:9194562)
(MGI:3762126|PMID:11359932)
SynGO
MGI
PMID:9194562 PMID:11359932 MGI:3653150 MGI:3762126 NCBI chrNW_004936596:2,990,367...2,995,935 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12142
    cellular process 11321
      exocytic process 66
        vesicle fusion to plasma membrane 14
          synaptic vesicle fusion to presynaptic active zone membrane 13
            negative regulation of synaptic vesicle fusion to presynaptic active zone membrane 0
            positive regulation of synaptic vesicle fusion to presynaptic active zone membrane + 5
            regulation of synaptic vesicle fusion to presynaptic active zone membrane + 10
Path 2
Term Annotations click to browse term
  biological_process 12142
    cellular process 11321
      cell communication 4369
        cell-cell signaling 1361
          synaptic signaling 660
            trans-synaptic signaling 639
              anterograde trans-synaptic signaling 631
                chemical synaptic transmission 631
                  neurotransmitter secretion 172
                    synaptic vesicle exocytosis 131
                      synaptic vesicle fusion to presynaptic active zone membrane 13
                        negative regulation of synaptic vesicle fusion to presynaptic active zone membrane 0
                        positive regulation of synaptic vesicle fusion to presynaptic active zone membrane + 5
                        regulation of synaptic vesicle fusion to presynaptic active zone membrane + 10
paths to the root