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ONTOLOGY REPORT - ANNOTATIONS

Term:synaptic vesicle fusion to presynaptic active zone membrane
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Accession:GO:0031629 term browser browse the term
Definition:Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft.
Synonyms:exact_synonym: synaptic vesicle fusion to pre-synaptic membrane;   synaptic vesicle fusion to presynaptic membrane
 broad_synonym: synaptic vesicle fusion

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synaptic vesicle fusion to presynaptic active zone membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRRT2 proline rich transmembrane protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:18,048,614...18,052,481 JBrowse link
G PRSS38 serine protease 38 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:50,972,132...51,008,027
Ensembl chr 2:50,831,116...51,006,694 		JBrowse link
G SNAP23 synaptosome associated protein 23 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:128,849,465...128,888,972
Ensembl chr 1:128,847,931...128,888,947 		JBrowse link
G SNAP29 synaptosome associated protein 29 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:50,492,187...50,511,475
Ensembl chr14:50,492,154...50,511,456 		JBrowse link
G SNAPIN SNAP associated protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:4430710|PMID:19217378) Ensembl
MGI		 PMID:19217378 GO_REF:0000107 MGI:4430710 NCBI chr 4:95,987,524...95,989,527
Ensembl chr 4:95,984,358...95,989,474 		JBrowse link
G STX11 syntaxin 11 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:21,127,871...21,170,321
Ensembl chr 1:21,127,559...21,159,691 		JBrowse link
G STX1A syntaxin 1A involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:10,974,127...10,991,846
Ensembl chr 3:10,974,126...10,991,874 		JBrowse link
G STX1B syntaxin 1B involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:17,439,563...17,459,517
Ensembl chr 3:17,439,581...17,459,516 		JBrowse link
G STX2 syntaxin 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:24,341,473...24,380,536
Ensembl chr14:24,341,333...24,380,630 		JBrowse link
G STX3 syntaxin 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:11,694,788...11,739,858
Ensembl chr 2:11,694,859...11,740,744 		JBrowse link
G STX4 syntaxin 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:17,422,266...17,431,377
Ensembl chr 3:17,416,842...17,431,053 		JBrowse link
calcium-dependent activation of synaptic vesicle fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRRT2 proline rich transmembrane protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:18,048,614...18,052,481 JBrowse link
G SYT1 synaptotagmin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:101,871,313...102,394,310
Ensembl chr 5:101,871,312...102,020,847 		JBrowse link
G SYT2 synaptotagmin 2 involved_in ISO (MGI:3695515|PMID:17192432) SynGO PMID:17192432 MGI:3695515 NCBI chr10:24,638,645...24,727,198
Ensembl chr10:24,638,704...24,669,846 		JBrowse link
G SYT7 synaptotagmin 7 involved_in ISO (MGI:5554634|PMID:24267651) SynGO PMID:24267651 MGI:5554634 NCBI chr 2:9,947,962...10,012,713
Ensembl chr 2:9,947,925...10,012,521 		JBrowse link
G SYT9 synaptotagmin 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:2,191,757...2,395,157
Ensembl chr 9:2,191,751...2,394,103 		JBrowse link
regulation of synaptic vesicle fusion to presynaptic active zone membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPLX1 complexin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:197,876...231,721
Ensembl chr 8:197,881...232,038 		JBrowse link
G CPLX2 complexin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:81,732,527...81,813,189
Ensembl chr 2:81,732,528...81,813,271 		JBrowse link
G CPLX3 complexin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:58,712,743...58,717,028
Ensembl chr 7:58,712,744...58,716,997 		JBrowse link
G GRIK5 glutamate ionotropic receptor kainate type subunit 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2449894|PMID:12533602) Ensembl
MGI		 PMID:12533602 GO_REF:0000107 MGI:2449894 NCBI chr 6:49,840,671...49,901,656
Ensembl chr 6:49,844,879...49,901,186 		JBrowse link
G RAB3A RAB3A, member RAS oncogene family involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3762126|PMID:11359932) Ensembl
MGI		 PMID:11359932 GO_REF:0000107 MGI:3762126 NCBI chr 2:59,603,090...59,609,773
Ensembl chr 2:59,603,117...59,609,767 		JBrowse link
G VAMP1 vesicle associated membrane protein 1 involved_in ISO (MGI:5427815|PMID:21282288) SynGO PMID:21282288 MGI:5427815 NCBI chr 5:64,181,496...64,188,275 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16518
    cellular process 15787
      exocytic process 87
        vesicle fusion to plasma membrane 22
          synaptic vesicle fusion to presynaptic active zone membrane 21
            negative regulation of synaptic vesicle fusion to presynaptic active zone membrane 0
            positive regulation of synaptic vesicle fusion to presynaptic active zone membrane + 5
            regulation of synaptic vesicle fusion to presynaptic active zone membrane + 11
Path 2
Term Annotations click to browse term
  biological_process 16518
    cellular process 15787
      cell communication 6614
        cell-cell signaling 1617
          synaptic signaling 854
            trans-synaptic signaling 825
              anterograde trans-synaptic signaling 817
                chemical synaptic transmission 817
                  neurotransmitter secretion 186
                    synaptic vesicle exocytosis 143
                      synaptic vesicle fusion to presynaptic active zone membrane 21
                        negative regulation of synaptic vesicle fusion to presynaptic active zone membrane 0
                        positive regulation of synaptic vesicle fusion to presynaptic active zone membrane + 5
                        regulation of synaptic vesicle fusion to presynaptic active zone membrane + 11
paths to the root