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ONTOLOGY REPORT - ANNOTATIONS


Term:synaptic vesicle fusion to presynaptic active zone membrane
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Accession:GO:0031629 term browser browse the term
Definition:Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft.
Synonyms:exact_synonym: synaptic vesicle fusion to pre-synaptic membrane;   synaptic vesicle fusion to presynaptic membrane
 broad_synonym: synaptic vesicle fusion


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synaptic vesicle fusion to presynaptic active zone membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC009133.6 novel transcript involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:29,812,261...29,820,092 JBrowse link
G PRRT2 proline rich transmembrane protein 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr16:29,812,193...29,815,920
Ensembl chr16:29,811,382...29,815,892
JBrowse link
G SNAP23 synaptosome associated protein 23 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:42,491,244...42,533,058
Ensembl chr15:42,491,233...42,545,356
JBrowse link
G SNAP25 synaptosome associated protein 25 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:10,218,830...10,307,420
Ensembl chr20:10,218,830...10,307,418
JBrowse link
G SNAP29 synaptosome associated protein 29 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr22:20,859,007...20,891,214
Ensembl chr22:20,859,007...20,891,214
JBrowse link
G SNAP47 synaptosome associated protein 47 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:227,728,168...227,781,228
Ensembl chr 1:227,728,539...227,781,231
Ensembl chr 1:227,728,539...227,781,231
JBrowse link
G SNAPIN SNAP associated protein involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4430710|PMID:19217378) Ensembl
MGI
PMID:19217378 GO_REF:0000107 MGI:4430710 NCBI chr 1:153,658,654...153,661,852
Ensembl chr 1:153,658,703...153,661,852
JBrowse link
G STX11 syntaxin 11 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:144,140,044...144,191,939
Ensembl chr 6:144,150,517...144,191,939
JBrowse link
G STX19 syntaxin 19 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:94,014,365...94,029,281
Ensembl chr 3:94,014,365...94,028,597
JBrowse link
G STX1A syntaxin 1A involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:73,699,210...73,719,673
Ensembl chr 7:73,699,206...73,719,672
JBrowse link
G STX1B syntaxin 1B involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:30,989,256...31,010,638
Ensembl chr16:30,989,256...31,010,638
JBrowse link
G STX2 syntaxin 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:130,789,600...130,839,274
Ensembl chr12:130,789,600...130,839,266
JBrowse link
G STX3 syntaxin 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:59,755,374...59,805,879
Ensembl chr11:59,713,456...59,805,882
JBrowse link
G STX4 syntaxin 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:31,033,095...31,040,168
Ensembl chr16:31,032,889...31,042,975
JBrowse link
calcium-dependent activation of synaptic vesicle fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC009133.6 novel transcript involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:29,812,261...29,820,092 JBrowse link
G PRRT2 proline rich transmembrane protein 2 involved_in ISO (MGI:5792766|PMID:27052163) SynGO PMID:27052163 MGI:5792766 NCBI chr16:29,812,193...29,815,920
Ensembl chr16:29,811,382...29,815,892
JBrowse link
G SYT1 synaptotagmin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:78,863,982...79,452,008
Ensembl chr12:78,863,993...79,452,008
JBrowse link
G SYT2 synaptotagmin 2 involved_in ISO (MGI:3695515|PMID:17192432) SynGO PMID:17192432 MGI:3695515 NCBI chr 1:202,590,596...202,710,454
Ensembl chr 1:202,590,596...202,710,454
JBrowse link
G SYT7 synaptotagmin 7 involved_in ISO (MGI:5554634|PMID:24267651) SynGO PMID:24267651 MGI:5554634 NCBI chr11:61,513,714...61,588,404
Ensembl chr11:61,513,714...61,581,148
Ensembl chr11:61,513,714...61,581,148
JBrowse link
G SYT9 synaptotagmin 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:7,238,784...7,470,032
Ensembl chr11:7,238,778...7,469,043
JBrowse link
regulation of synaptic vesicle fusion to presynaptic active zone membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPLX1 complexin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:784,957...826,129
Ensembl chr 4:784,957...826,129
JBrowse link
G CPLX2 complexin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:175,796,533...175,884,021
Ensembl chr 5:175,796,310...175,884,021
JBrowse link
G CPLX3 complexin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:74,826,627...74,831,802
Ensembl chr15:74,826,627...74,831,802
JBrowse link
G GRIK5 glutamate ionotropic receptor kainate type subunit 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2449894|PMID:12533602) Ensembl
MGI
PMID:12533602 GO_REF:0000107 MGI:2449894 NCBI chr19:41,998,316...42,071,804
Ensembl chr19:41,998,321...42,069,498
JBrowse link
G RAB3A RAB3A, member RAS oncogene family involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
(MGI:3762126|PMID:11359932)
(PMID:21873635)
ParkinsonsUK-UCL
MGI
GO_Central
PMID:11359932 PMID:21873635 GO_REF:0000024 MGI:3762126 NCBI chr19:18,196,784...18,204,042
Ensembl chr19:18,196,784...18,204,042
JBrowse link
G STXBP1 syntaxin binding protein 1 involved_in TAS (PMID:15217342) ParkinsonsUK-UCL PMID:15217342 NCBI chr 9:127,611,912...127,696,029
Ensembl chr 9:127,579,370...127,696,027
JBrowse link
G VAMP1 vesicle associated membrane protein 1 involved_in ISO (MGI:5427815|PMID:21282288) SynGO PMID:21282288 MGI:5427815 NCBI chr12:6,462,237...6,470,677
Ensembl chr12:6,462,237...6,470,987
Ensembl chr12:6,462,237...6,470,987
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18680
    cellular process 17729
      exocytic process 97
        vesicle fusion to plasma membrane 26
          synaptic vesicle fusion to presynaptic active zone membrane 25
            negative regulation of synaptic vesicle fusion to presynaptic active zone membrane 0
            positive regulation of synaptic vesicle fusion to presynaptic active zone membrane + 6
            regulation of synaptic vesicle fusion to presynaptic active zone membrane + 13
Path 2
Term Annotations click to browse term
  biological_process 18680
    cellular process 17729
      cell communication 7385
        cell-cell signaling 2074
          synaptic signaling 1003
            trans-synaptic signaling 974
              anterograde trans-synaptic signaling 965
                chemical synaptic transmission 965
                  neurotransmitter secretion 210
                    synaptic vesicle exocytosis 154
                      synaptic vesicle fusion to presynaptic active zone membrane 25
                        negative regulation of synaptic vesicle fusion to presynaptic active zone membrane 0
                        positive regulation of synaptic vesicle fusion to presynaptic active zone membrane + 6
                        regulation of synaptic vesicle fusion to presynaptic active zone membrane + 13
paths to the root