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ONTOLOGY REPORT - ANNOTATIONS


Term:synaptic vesicle fusion to presynaptic active zone membrane
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Accession:GO:0031629 term browser browse the term
Definition:Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft.
Synonyms:exact_synonym: synaptic vesicle fusion to pre-synaptic membrane;   synaptic vesicle fusion to presynaptic membrane
 broad_synonym: synaptic vesicle fusion


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synaptic vesicle fusion to presynaptic active zone membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRRT2 proline rich transmembrane protein 2 involved_in ISO (MGI:5792766|PMID:27052163) UniProt PMID:27052163 MGI:5792766 NCBI chr 6:17,872,670...17,877,502
Ensembl chr 6:17,873,521...17,903,184
JBrowse link
G SNAP23 synaptosome associated protein 23 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr30:9,453,931...9,493,506
Ensembl chr30:9,456,084...9,492,329
JBrowse link
G SNAP25 synaptosome associated protein 25 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr24:12,003,005...12,081,385
Ensembl chr24:12,004,117...12,081,329
JBrowse link
G SNAP29 synaptosome associated protein 29 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr26:30,606,195...30,630,441
Ensembl chr26:30,609,158...30,630,262
JBrowse link
G SNAP47 synaptosome associated protein 47 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:1,058,891...1,104,568
Ensembl chr14:1,056,802...1,104,574
JBrowse link
G SNAPIN SNAP associated protein involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4430710|PMID:19217378) Ensembl
MGI
PMID:19217378 GO_REF:0000107 MGI:4430710 NCBI chr 7:43,410,554...43,411,929
Ensembl chr 7:43,410,998...43,412,323
JBrowse link
G STX11 syntaxin 11 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:35,600,440...35,645,421
Ensembl chr 1:35,601,133...35,644,819
JBrowse link
G STX19 syntaxin 19 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr33:1,726,019...1,736,949
Ensembl chr33:1,726,695...1,727,579
JBrowse link
G STX1A syntaxin 1A involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:6,574,616...6,583,002
Ensembl chr 6:6,574,631...6,581,833
JBrowse link
G STX1B syntaxin 1B involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 6:17,209,972...17,219,903
Ensembl chr 6:17,210,433...17,241,363
JBrowse link
G STX2 syntaxin 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr26:1,459,110...1,494,801
Ensembl chr26:1,454,189...1,494,823
JBrowse link
G STX3 syntaxin 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr21:50,298,040...50,322,773
Ensembl chr21:50,298,158...50,318,663
JBrowse link
G STX4 syntaxin 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:17,184,044...17,189,481
Ensembl chr 6:17,184,399...17,189,370
JBrowse link
calcium-dependent activation of synaptic vesicle fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRRT2 proline rich transmembrane protein 2 involved_in ISO (MGI:5792766|PMID:27052163) SynGO PMID:27052163 MGI:5792766 NCBI chr 6:17,872,670...17,877,502
Ensembl chr 6:17,873,521...17,903,184
JBrowse link
G SYT1 synaptotagmin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:21,629,061...22,042,734
Ensembl chr15:21,834,763...22,042,732
JBrowse link
G SYT2 synaptotagmin 2 involved_in ISO (MGI:3695515|PMID:17192432) SynGO PMID:17192432 MGI:3695515 NCBI chr 7:497,387...509,338
Ensembl chr 7:497,394...502,952
JBrowse link
G SYT7 synaptotagmin 7 involved_in ISO (MGI:5554634|PMID:24267651) SynGO PMID:24267651 MGI:5554634 NCBI chr18:54,863,072...54,926,121
Ensembl chr18:54,861,754...54,921,367
JBrowse link
G SYT9 synaptotagmin 9 involved_in ISO (MGI:3714434|PMID:17521570) SynGO PMID:17521570 MGI:3714434 NCBI chr21:30,985,059...31,123,986
Ensembl chr21:30,986,521...31,162,414
JBrowse link
regulation of synaptic vesicle fusion to presynaptic active zone membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPLX1 complexin 1 involved_in ISO (MGI:2679622|PMID:11163241) SynGO PMID:11163241 MGI:2679622 NCBI chr 3:91,635,953...91,658,084
Ensembl chr 3:91,638,515...91,656,737
JBrowse link
G CPLX2 complexin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:37,203,003...37,275,938
Ensembl chr 4:37,206,082...37,275,954
JBrowse link
G CPLX3 complexin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:37,888,770...37,893,168
Ensembl chr30:37,888,076...37,893,182
JBrowse link
G GRIK5 glutamate ionotropic receptor kainate type subunit 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2449894|PMID:12533602) Ensembl
MGI
PMID:12533602 GO_REF:0000107 MGI:2449894 NCBI chr 1:112,270,157...112,321,672
Ensembl chr 1:112,270,424...112,321,672
JBrowse link
G RAB3A RAB3A, member RAS oncogene family involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(MGI:3762126|PMID:11359932)
(PMID:21873635)
Ensembl
MGI
GO_Central
PMID:11359932 PMID:21873635 GO_REF:0000107 MGI:3762126 NCBI chr20:44,796,740...44,802,224
Ensembl chr20:44,796,895...44,801,692
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16153
    cellular process 15480
      exocytic process 92
        vesicle fusion to plasma membrane 23
          synaptic vesicle fusion to presynaptic active zone membrane 22
            negative regulation of synaptic vesicle fusion to presynaptic active zone membrane 0
            positive regulation of synaptic vesicle fusion to presynaptic active zone membrane + 5
            regulation of synaptic vesicle fusion to presynaptic active zone membrane + 10
Path 2
Term Annotations click to browse term
  biological_process 16153
    cellular process 15480
      cell communication 6196
        cell-cell signaling 1634
          synaptic signaling 865
            trans-synaptic signaling 839
              anterograde trans-synaptic signaling 830
                chemical synaptic transmission 830
                  neurotransmitter secretion 191
                    synaptic vesicle exocytosis 145
                      synaptic vesicle fusion to presynaptic active zone membrane 22
                        negative regulation of synaptic vesicle fusion to presynaptic active zone membrane 0
                        positive regulation of synaptic vesicle fusion to presynaptic active zone membrane + 5
                        regulation of synaptic vesicle fusion to presynaptic active zone membrane + 10
paths to the root