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ONTOLOGY REPORT - ANNOTATIONS


Term:synaptic vesicle fusion to presynaptic active zone membrane
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Accession:GO:0031629 term browser browse the term
Definition:Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft.
Synonyms:exact_synonym: synaptic vesicle fusion to pre-synaptic membrane;   synaptic vesicle fusion to presynaptic membrane
 broad_synonym: synaptic vesicle fusion


show annotations for term's descendants           Sort by:
 
synaptic vesicle fusion to presynaptic active zone membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRRT2 proline rich transmembrane protein 2 involved_in ISO (MGI:5792766|PMID:27052163) UniProt PMID:27052163 MGI:5792766 Ensembl chr16:30,183,352...30,187,862 JBrowse link
G SNAPIN SNAP associated protein acts_upstream_of_or_within ISO (MGI:4430710|PMID:19217378) MGI PMID:19217378 MGI:4430710 NCBI chr 1:129,014,668...129,018,428
Ensembl chr 1:132,644,320...132,647,095
JBrowse link
G STX1A syntaxin 1A involved_in ISO PMID:18703708 SynGO PMID:18703708 RGD:11535099 Ensembl chr 7:80,852,495...80,862,255 JBrowse link
G STX1B syntaxin 1B involved_in ISO (MGI:5603022|PMID:24587181)
(MGI:3803800|PMID:18703708), (MGI:5603022|PMID:24587181)
SynGO PMID:18703708 PMID:24587181 MGI:3803800 MGI:5603022 NCBI chr16:23,956,426...23,979,646
Ensembl chr16:31,356,907...31,378,870
JBrowse link
calcium-dependent activation of synaptic vesicle fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRRT2 proline rich transmembrane protein 2 involved_in ISO (MGI:5792766|PMID:27052163) SynGO PMID:27052163 MGI:5792766 Ensembl chr16:30,183,352...30,187,862 JBrowse link
G SYT1 synaptotagmin 1 involved_in ISO (MGI:69538|PMID:7954835) SynGO PMID:7954835 MGI:69538 NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923
JBrowse link
G SYT2 synaptotagmin 2 involved_in ISO (MGI:3695515|PMID:17192432) SynGO PMID:17192432 MGI:3695515 NCBI chr 1:178,187,872...178,308,522
Ensembl chr 1:182,490,401...182,538,123
JBrowse link
G SYT7 synaptotagmin 7 involved_in ISO (MGI:5554634|PMID:24267651) SynGO PMID:24267651 MGI:5554634 NCBI chr11:56,814,694...56,880,439
Ensembl chr11:60,175,403...60,242,375
JBrowse link
G SYT9 synaptotagmin 9 involved_in ISO (MGI:3714434|PMID:17521570) SynGO PMID:17521570 MGI:3714434 NCBI chr11:7,350,612...7,565,272
Ensembl chr11:7,032,803...7,247,187
JBrowse link
regulation of synaptic vesicle fusion to presynaptic active zone membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPLX1 complexin 1 involved_in ISO (MGI:2679622|PMID:11163241) SynGO PMID:11163241 MGI:2679622 NCBI chr 4:889,037...930,046
Ensembl chr 4:819,833...858,953
JBrowse link
G CPLX2 complexin 2 involved_in ISO (MGI:2679622|PMID:11163241) SynGO PMID:11163241 MGI:2679622 NCBI chr 5:171,144,671...171,233,028
Ensembl chr 5:178,115,947...178,128,595
JBrowse link
G CPLX3 complexin 3 involved_in ISO (MGI:5818105|PMID:27239031) SynGO PMID:27239031 MGI:5818105 NCBI chr15:53,769,138...53,774,330
Ensembl chr15:73,386,826...73,391,991
JBrowse link
G GRIK5 glutamate ionotropic receptor kainate type subunit 5 acts_upstream_of_or_within ISO (MGI:2449894|PMID:12533602) MGI PMID:12533602 MGI:2449894 NCBI chr19:38,886,108...38,956,938
Ensembl chr19:47,389,804...47,544,604
JBrowse link
G RAB3A RAB3A, member RAS oncogene family acts_upstream_of_or_within
involved_in
ISO (MGI:3762126|PMID:11359932)
(MGI:3653150|PMID:9194562)
MGI
SynGO
PMID:9194562 PMID:11359932 MGI:3653150 MGI:3762126 NCBI chr19:17,672,661...17,679,541
Ensembl chr19:18,649,166...18,656,768
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12629
    cellular process 11745
      exocytic process 66
        vesicle fusion to plasma membrane 14
          synaptic vesicle fusion to presynaptic active zone membrane 13
            negative regulation of synaptic vesicle fusion to presynaptic active zone membrane 0
            positive regulation of synaptic vesicle fusion to presynaptic active zone membrane + 5
            regulation of synaptic vesicle fusion to presynaptic active zone membrane + 10
Path 2
Term Annotations click to browse term
  biological_process 12629
    cellular process 11745
      cell communication 4475
        cell-cell signaling 1379
          synaptic signaling 666
            trans-synaptic signaling 645
              anterograde trans-synaptic signaling 637
                chemical synaptic transmission 637
                  neurotransmitter secretion 171
                    synaptic vesicle exocytosis 130
                      synaptic vesicle fusion to presynaptic active zone membrane 13
                        negative regulation of synaptic vesicle fusion to presynaptic active zone membrane 0
                        positive regulation of synaptic vesicle fusion to presynaptic active zone membrane + 5
                        regulation of synaptic vesicle fusion to presynaptic active zone membrane + 10
paths to the root