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ONTOLOGY REPORT - ANNOTATIONS

Term:receptor internalization
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Accession:GO:0031623 term browser browse the term
Definition:A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane.


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receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2179948 (MGI:3609472|PMID:14645660)		 Ensembl
RGD		 PMID:14645660 GO_REF:0000107 MGI:3609472 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Ackr3 atypical chemokine receptor 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:22300987), (PMID:22457824)		 UniProt
RGD		 PMID:22300987 PMID:22457824 GO_REF:0000024 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237 		JBrowse link
G Adm adrenomedullin involved_in ISO (PMID:10882736), (PMID:15613468), (PMID:20074556) RGD PMID:10882736 PMID:15613468 PMID:20074556 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 involved_in ISO (PMID:25898166) RGD PMID:25898166 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140 		JBrowse link
G Arrb2 arrestin, beta 2 involved_in ISO (PMID:12958365) RGD PMID:12958365 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Calca calcitonin-related polypeptide alpha involved_in ISO (PMID:10882736) RGD PMID:10882736 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Calcrl calcitonin receptor like receptor involved_in ISO (PMID:10882736), (PMID:20074556) RGD PMID:10882736 PMID:20074556 NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910 		JBrowse link
G Cav1 caveolin 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:25893292)		 UniProt
RGD		 PMID:25893292 GO_REF:0000024 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cd36 CD36 molecule involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5700288|PMID:23395392)		 UniProt
Ensembl
RGD		 PMID:23395392 GO_REF:0000024 GO_REF:0000107 MGI:5700288 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd36-ps1 CD36 molecule, pseudogene 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:17,487,837...17,514,900 JBrowse link
G Cd81 Cd81 molecule involved_in ISS
ISO		 GO_REF:0000024
(MGI:5700288|PMID:23395392)		 UniProt
RGD		 PMID:23395392 GO_REF:0000024 MGI:5700288 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Cd9 CD9 molecule involved_in ISS
ISO		 GO_REF:0000024
(MGI:5700288|PMID:23395392)		 UniProt
RGD		 PMID:23395392 GO_REF:0000024 MGI:5700288 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222 		JBrowse link
G Cltc clathrin heavy chain involved_in ISO
IEA		 (PMID:14985334)
GO_REF:0000107		 RGD
Ensembl		 PMID:14985334 GO_REF:0000107 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737 		JBrowse link
G Cntn2 contactin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3801368|PMID:18550718)		 Ensembl
RGD		 PMID:18550718 GO_REF:0000107 MGI:3801368 NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887 		JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 involved_in ISO (PMID:10734056) RGD PMID:10734056 NCBI chr 9:75,768,124...75,771,122
Ensembl chr 9:75,766,770...75,771,084 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 involved_in ISO (PMID:10734056) RGD PMID:10734056 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425 		JBrowse link
G Dnm1 dynamin 1 involved_in IMP
IBA		 PMID:11100149
PMID:21873635		 UniProt
GO_Central		 PMID:11100149 PMID:21873635 RGD:8554168, RGD:13792537 NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538 		JBrowse link
G Dnm2 dynamin 2 involved_in ISO
IBA		 (PMID:14985334)
PMID:21873635		 RGD PMID:14985334 PMID:21873635 RGD:13792537 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157 		JBrowse link
G Dnm3 dynamin 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:74,359,043...74,838,135
Ensembl chr13:74,359,213...74,838,108 		JBrowse link
G Entrep1 endosomal transmembrane epsin interactor 1 acts_upstream_of ISO (PMID:34927784) RGD PMID:34927784 NCBI chr 1:221,592,500...221,646,603
Ensembl chr 1:221,592,503...221,646,758 		JBrowse link
G Ezr ezrin acts_upstream_of_or_within ISO (MGI:3612236|PMID:16365167) RGD PMID:16365167 MGI:3612236 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G Fcer1g Fc epsilon receptor Ig involved_in ISS
ISO		 GO_REF:0000024
(MGI:5700288|PMID:23395392)		 UniProt
RGD		 PMID:23395392 GO_REF:0000024 MGI:5700288 NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Ghr growth hormone receptor involved_in
NOT|involved_in		 ISO (PMID:9360546) RGD PMID:9360546 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Grb2 growth factor receptor bound protein 2 involved_in ISO (PMID:14985334) RGD PMID:14985334 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 involved_in IEA
ISO
IDA		 GO_REF:0000107
(MGI:2653003|PMID:12628184)
PMID:11100149		 Ensembl
RGD		 PMID:12628184 PMID:11100149 GO_REF:0000107 MGI:2653003, RGD:8554168 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 involved_in IDA PMID:11100149 UniProt PMID:11100149 RGD:8554168 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 involved_in ISO
IEA		 (PMID:20074556)
GO_REF:0000107		 RGD
Ensembl		 PMID:20074556 GO_REF:0000107 NCBI chr 1:201,581,480...201,601,580
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 involved_in ISO
IEA		 (PMID:20074556)
GO_REF:0000107		 RGD
Ensembl		 PMID:20074556 GO_REF:0000107 NCBI chr12:43,624,778...43,735,375
Ensembl chr12:43,624,897...43,731,262 		JBrowse link
G Grk4 G protein-coupled receptor kinase 4 involved_in ISO (PMID:20074556) RGD PMID:20074556 NCBI chr14:75,998,554...76,080,808
Ensembl chr14:76,006,218...76,080,693 		JBrowse link
G Hgs hepatocyte growth factor-regulated tyrosine kinase substrate involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:105,739,617...105,757,838
Ensembl chr10:105,739,296...105,757,835 		JBrowse link
G Ins1 insulin 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Ins2 insulin 2 acts_upstream_of_or_within ISO (MGI:7316520|PMID:17264162) RGD PMID:17264162 MGI:7316520 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Insr insulin receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:7316520|PMID:17264162)
GO_REF:0000107		 RGD
Ensembl		 PMID:17264162 GO_REF:0000107 MGI:7316520 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Itgb1 integrin subunit beta 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5700288|PMID:23395392)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:23395392 GO_REF:0000024 GO_REF:0000107 MGI:5700288 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Itgb2 integrin subunit beta 2 involved_in ISO (MGI:5700288|PMID:23395392) RGD PMID:23395392 MGI:5700288 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO (PMID:15166224) RGD PMID:15166224 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:9151699) RGD PMID:9151699 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (PMID:26005850)
GO_REF:0000114		 RGD
ComplexPortal		 PMID:26005850 GO_REF:0000114 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G LRRTM1 leucine rich repeat transmembrane neuronal 1 acts_upstream_of ISO MGI:2389174 (MGI:5515239|PMID:23931994) RGD PMID:23931994 MGI:5515239 NCBI chr 4:109,701,815...109,718,924
Ensembl chr 4:109,701,815...109,717,184 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase involved_in ISO
IBA		 (PMID:18544533)
PMID:21873635		 RGD PMID:18544533 PMID:21873635 RGD:13792537 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951 		JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in ISO
IEA		 (PMID:14985334), (PMID:25898166)
GO_REF:0000107		 RGD
Ensembl		 PMID:14985334 PMID:25898166 GO_REF:0000107 NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557 		JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:15937517 RGD:10043344 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Rab31 RAB31, member RAS oncogene family involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:19725050)		 Ensembl
UniProt
RGD		 PMID:19725050 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:105,246,712...105,382,973
Ensembl chr 9:105,246,709...105,381,253 		JBrowse link
G Rala RAS like proto-oncogene A involved_in ISO UniProtKB:P11234 (PMID:34096503) RGD PMID:34096503 NCBI chr17:47,092,139...47,145,192
Ensembl chr17:47,092,207...47,144,063 		JBrowse link
G Ralb RAS like proto-oncogene B involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P11233 (PMID:34096503)		 Ensembl
RGD		 PMID:34096503 GO_REF:0000107 NCBI chr13:30,588,036...30,624,199
Ensembl chr13:30,588,033...30,624,202 		JBrowse link
G Ramp1 receptor activity modifying protein 1 involved_in IBA
IDA
ISO		 PMID:21873635
PMID:15613468
(PMID:10882736), (PMID:15613468)		 RGD PMID:10882736 PMID:15613468 PMID:21873635 PMID:15613468 RGD:13792537, RGD:8554018 NCBI chr 9:91,765,481...91,816,152
Ensembl chr 9:91,781,285...91,816,151 		JBrowse link
G Ramp2 receptor activity modifying protein 2 involved_in ISO
IBA
IDA		 (PMID:10882736), (PMID:15613468), (PMID:20074556)
PMID:21873635		 RGD PMID:10882736 PMID:15613468 PMID:20074556 PMID:21873635 PMID:15613468 RGD:13792537, RGD:8554018 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
G Ramp3 receptor activity modifying protein 3 involved_in ISO
IBA		 (PMID:10882736), (PMID:15613468)
PMID:21873635		 RGD PMID:10882736 PMID:15613468 PMID:21873635 RGD:13792537 NCBI chr14:81,527,404...81,544,905
Ensembl chr14:81,527,385...81,544,902 		JBrowse link
G RGD1565355 similar to fatty acid translocase/CD36 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:17,424,749...17,465,808
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Snca synuclein alpha involved_in ISO (PMID:18980610) RGD PMID:18980610 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Snx1 sorting nexin 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20070609)		 UniProt
RGD		 PMID:20070609 GO_REF:0000024 NCBI chr 8:66,630,086...66,670,418
Ensembl chr 8:66,630,086...66,670,360 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5700288|PMID:23395392)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:23395392 GO_REF:0000024 GO_REF:0000107 MGI:5700288 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tfrc transferrin receptor involved_in ISO
IEA
ISS		 (PMID:26642240)
GO_REF:0000104
GO_REF:0000024		 RGD
UniProt		 PMID:26642240 GO_REF:0000024 GO_REF:0000104 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 acts_upstream_of_or_within ISO (MGI:3706258|PMID:17389358) RGD PMID:17389358 MGI:3706258 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966 		JBrowse link
G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin involved_in ISO (PMID:10882736) RGD PMID:10882736 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Arr3 arrestin 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:65,699,881...65,712,224
Ensembl chr  X:65,698,699...65,712,153 		JBrowse link
G Arrb1 arrestin, beta 1 involved_in IBA
ISO		 PMID:21873635
(PMID:10521508), (PMID:12582207)		 RGD PMID:10521508 PMID:12582207 PMID:21873635 RGD:13792537 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Arrb2 arrestin, beta 2 involved_in IBA
ISO		 PMID:21873635
(PMID:10644702), (PMID:12582207)		 RGD PMID:10644702 PMID:12582207 PMID:21873635 RGD:13792537 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Calca calcitonin-related polypeptide alpha involved_in ISO (PMID:10882736) RGD PMID:10882736 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Dnm1 dynamin 1 IMP RGD PMID:14709338 RGD:9685157 NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538 		JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:14709338 RGD:9685157 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157 		JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:14617818 RGD:1581465 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 involved_in IDA
ISO		 (PMID:18424554) RGD PMID:18424554 PMID:14617818 RGD:1581465 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Grk4 G protein-coupled receptor kinase 4 IMP RGD PMID:12519791 RGD:1304268 NCBI chr14:75,998,554...76,080,808
Ensembl chr14:76,006,218...76,080,693 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B involved_in ISO (MGI:4821070|PMID:17325130) RGD PMID:17325130 MGI:4821070 NCBI chr 8:82,513,572...82,534,892
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in IEA
ISO		 GO_REF:0000107
(MGI:4821070|PMID:17325130)		 Ensembl
RGD		 PMID:17325130 GO_REF:0000107 MGI:4821070 NCBI chr 9:86,735,793...86,756,640
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Pld2 phospholipase D2 acts_upstream_of_or_within ISO (MGI:3042801|PMID:14718562) RGD PMID:14718562 MGI:3042801 NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808 		JBrowse link
G Sag S-antigen visual arrestin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:88,467,797...88,508,821
Ensembl chr 9:88,469,376...88,508,820 		JBrowse link
insulin receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in ISO (MGI:6378123|PMID:27110488) RGD PMID:27110488 MGI:6378123 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in IDA PMID:9712832
PMID:7592607		 UniProt PMID:9712832 PMID:7592607 RGD:11059573, RGD:11059580 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Lmbrd1 LMBR1 domain containing 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:5559223 (MGI:5543853|PMID:24078630)		 UniProt
RGD		 PMID:24078630 GO_REF:0000024 MGI:5543853 NCBI chr 9:27,096,387...27,178,095
Ensembl chr 9:27,096,297...27,178,090 		JBrowse link
negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Necab2 N-terminal EF-hand calcium binding protein 2 involved_in ISO
IEA		 (PMID:17689978)
GO_REF:0000107		 RGD
Ensembl		 PMID:17689978 GO_REF:0000107 NCBI chr19:47,501,351...47,527,722
Ensembl chr19:47,501,302...47,527,684 		JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18199683) RGD PMID:18199683 NCBI chr  X:17,853,086...17,856,505
Ensembl chr  X:17,853,114...17,856,505 		JBrowse link
negative regulation of receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd13a ankyrin repeat domain 13a involved_in ISO (PMID:22298428) RGD PMID:22298428 NCBI chr12:41,798,196...41,828,327
Ensembl chr12:41,798,199...41,829,327 		JBrowse link
G Ankrd13b ankyrin repeat domain 13B involved_in ISO (PMID:22298428) RGD PMID:22298428 NCBI chr10:62,319,660...62,338,342
Ensembl chr10:62,319,647...62,340,253 		JBrowse link
G Ankrd13d ankyrin repeat domain 13D involved_in ISO (PMID:22298428) RGD PMID:22298428 NCBI chr 1:201,565,712...201,577,987
Ensembl chr 1:201,565,712...201,577,933 		JBrowse link
G Anxa2 annexin A2 involved_in ISO (PMID:18799458) RGD PMID:18799458 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Atxn2 ataxin 2 involved_in ISO (PMID:18602463) RGD PMID:18602463 NCBI chr12:34,754,132...34,851,175
Ensembl chr12:34,754,137...34,851,479 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 involved_in IDA PMID:11526121 UniProt PMID:11526121 RGD:8554437 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 IMP RGD PMID:17881561 RGD:12050150 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 involved_in ISO
IBA		 ComplexPortal:CPX-1134|UniProtKB:P04925 (PMID:23386614)
PMID:21873635		 RGD PMID:23386614 PMID:21873635 RGD:13792537 NCBI chr14:75,651,371...75,663,380
Ensembl chr14:75,651,376...75,665,414 		JBrowse link
G LRRTM1 leucine rich repeat transmembrane neuronal 1 acts_upstream_of_or_within ISO MGI:2389174 (MGI:5515239|PMID:23931994) RGD PMID:23931994 MGI:5515239 NCBI chr 4:109,701,815...109,718,924
Ensembl chr 4:109,701,815...109,717,184 		JBrowse link
G Lrrtm2 leucine rich repeat transmembrane neuronal 2 acts_upstream_of_or_within ISO MGI:2389173 (MGI:5515239|PMID:23931994) RGD PMID:23931994 MGI:5515239 NCBI chr18:26,817,816...26,822,864
Ensembl chr18:26,817,816...26,822,864 		JBrowse link
G Mir199a2 microRNA 199a-2 involved_in ISO (PMID:26163491) RGD PMID:26163491 NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063 		JBrowse link
G Mtmr2 myotubularin related protein 2 involved_in IMP PMID:20410104 BHF-UCL PMID:20410104 RGD:8553482 NCBI chr 8:10,617,993...10,670,724
Ensembl chr 8:10,617,993...10,668,172 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:18799458) RGD PMID:18799458 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688 		JBrowse link
G Rin3 Ras and Rab interactor 3 acts_upstream_of_or_within ISO (PMID:23185384) RGD PMID:23185384 NCBI chr 6:121,431,803...121,540,957
Ensembl chr 6:121,431,339...121,540,957 		JBrowse link
G Sdcbp syndecan binding protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:25893292)		 UniProt
RGD		 PMID:25893292 GO_REF:0000024 NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572 		JBrowse link
G Wdr54 WD repeat domain 54 involved_in ISO (PMID:30458214) RGD PMID:30458214 NCBI chr 4:115,654,968...115,677,979
Ensembl chr 4:115,654,968...115,661,562 		JBrowse link
neurotransmitter receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap2b1 adaptor related protein complex 2 subunit beta 1 involved_in ISO (MGI:5819335|PMID:24217640) RGD PMID:24217640 MGI:5819335 NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013 		JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 involved_in IBA
ISO		 PMID:21873635
(MGI:5819335|PMID:24217640)		 RGD PMID:24217640 PMID:21873635 MGI:5819335, RGD:13792537 NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227 		JBrowse link
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:177,201,990...177,296,473
Ensembl chr 1:177,201,288...177,297,024 		JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:92,686,100...92,745,601
Ensembl chr10:92,683,761...92,746,126 		JBrowse link
G Cacng5 calcium voltage-gated channel auxiliary subunit gamma 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:92,827,441...92,869,632
Ensembl chr10:92,829,196...92,869,614 		JBrowse link
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:65,800,820...65,831,165
Ensembl chr 1:65,800,355...65,831,006 		JBrowse link
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:65,755,334...65,775,567
Ensembl chr 1:65,755,334...65,779,089 		JBrowse link
G Snap25 synaptosome associated protein 25 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4411959|PMID:19679075)		 Ensembl
RGD		 PMID:19679075 GO_REF:0000107 MGI:4411959 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760 		JBrowse link
positive regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apela apelin receptor early endogenous ligand involved_in ISO (PMID:25639753) RGD PMID:25639753 NCBI chr16:24,694,231...24,703,466
Ensembl chr16:24,694,324...24,703,465 		JBrowse link
G Apln apelin involved_in ISO
IDA		 (PMID:11359874)
(MGI:5902690|PMID:11359874)		 RGD PMID:11359874 PMID:11359874 MGI:5902690, RGD:12907555 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G App amyloid beta precursor protein involved_in ISO (PMID:18723082) RGD PMID:18723082 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
positive regulation of receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahi1 Abelson helper integration site 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4840150|PMID:20956301)		 UniProt
RGD		 PMID:20956301 GO_REF:0000024 MGI:4840150 NCBI chr 1:15,768,047...15,886,744
Ensembl chr 1:15,762,462...15,891,041 		JBrowse link
G Angpt1 angiopoietin 1 involved_in ISO
IEA		 (PMID:19424712)
GO_REF:0000107		 RGD
Ensembl		 PMID:19424712 GO_REF:0000107 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 IMP RGD PMID:12105201 RGD:13461854 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140 		JBrowse link
G Arrb1 arrestin, beta 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:22457824)		 UniProt
RGD		 PMID:22457824 GO_REF:0000024 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Arrb2 arrestin, beta 2 involved_in IMP
ISO		 Oprm1
(PMID:22457824)		 RGD PMID:22457824 PMID:16120787 RGD:5510008 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Atad1 ATPase family, AAA domain containing 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5050342|PMID:21496646)		 UniProt
RGD		 PMID:21496646 GO_REF:0000024 MGI:5050342 NCBI chr 1:230,544,227...230,610,524
Ensembl chr 1:230,544,047...230,596,548 		JBrowse link
G Cd63 Cd63 molecule involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23632027)		 UniProt
Ensembl
RGD		 PMID:23632027 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178 		JBrowse link
G Dab2 DAB adaptor protein 2 involved_in ISO (MGI:5476876|PMID:23354168) RGD PMID:23354168 MGI:5476876 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Drd2 dopamine receptor D2 IMP RGD PMID:18809670 RGD:2311559 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 IMP RGD PMID:17989303 RGD:8553895 NCBI chr17:19,685,218...19,776,668
Ensembl chr17:19,685,215...19,776,661 		JBrowse link
G Egf epidermal growth factor involved_in ISO
IEA		 (PMID:22732145)
GO_REF:0000107		 RGD
Ensembl		 PMID:22732145 GO_REF:0000107 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:25561520)		 UniProt
RGD		 PMID:25561520 GO_REF:0000024 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Gh1 growth hormone 1 NOT|involved_in ISO (PMID:9360546) RGD PMID:9360546 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (MGI:4845816|PMID:20660291) RGD PMID:20660291 MGI:4845816 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in ISO (PMID:15514116) RGD PMID:15514116 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Insr insulin receptor involved_in ISO (PMID:25401701) RGD PMID:25401701 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 involved_in ISO
ISS		 (PMID:11526121)
GO_REF:0000024		 RGD
UniProt		 PMID:11526121 GO_REF:0000024 NCBI chr 4:14,388,322...15,870,036
Ensembl chr 4:14,386,399...15,870,240 		JBrowse link
G Ntf3 neurotrophin 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:23027130)		 Ensembl
RGD		 PMID:23027130 GO_REF:0000107 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596 		JBrowse link
G Pard3 par-3 family cell polarity regulator involved_in ISO (MGI:5476876|PMID:23354168) RGD PMID:23354168 MGI:5476876 NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:17328821) RGD PMID:17328821 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688 		JBrowse link
G Pick1 protein interacting with PRKCA 1 involved_in IBA
IDA		 PMID:21873635
PMID:18297063		 GO_Central
UniProt		 PMID:21873635 PMID:18297063 RGD:13792537, RGD:8554748 NCBI chr 7:110,796,623...110,816,850
Ensembl chr 7:110,797,117...110,816,848 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5300392|PMID:22078883)		 Ensembl
RGD		 PMID:22078883 GO_REF:0000107 MGI:5300392 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Plk2 polo-like kinase 2 IMP RGD PMID:20802490 RGD:152995511 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947 		JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 IMP RGD PMID:19625523 RGD:9835004 NCBI chr 1:97,620,638...97,681,186
Ensembl chr 1:97,620,642...97,679,882 		JBrowse link
G Scyl2 SCY1 like pseudokinase 2 involved_in ISO (PMID:19643732) RGD PMID:19643732 NCBI chr 7:24,064,404...24,117,338
Ensembl chr 7:24,064,404...24,117,305 		JBrowse link
G Sele selectin E involved_in ISO (PMID:9312078) RGD PMID:9312078 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741 		JBrowse link
G Sfrp4 secreted frizzled-related protein 4 involved_in ISO
IEA		 (PMID:16151791)
GO_REF:0000107		 RGD
Ensembl		 PMID:16151791 GO_REF:0000107 NCBI chr17:45,278,867...45,330,806
Ensembl chr17:45,234,097...45,330,736 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in IEA
ISO		 GO_REF:0000107
(MGI:5300392|PMID:22078883), (MGI:5619729|PMID:23962979)		 Ensembl
RGD		 PMID:22078883 PMID:23962979 GO_REF:0000107 MGI:5300392 MGI:5619729 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Synj2bp synaptojanin 2 binding protein involved_in ISO (MGI:3623710|PMID:16648306) RGD PMID:16648306 MGI:3623710 NCBI chr 6:101,189,714...101,227,400
Ensembl chr 6:101,189,714...101,227,406 		JBrowse link
G Tbc1d5 TBC1 domain family, member 5 involved_in ISO (PMID:22354992) RGD PMID:22354992 NCBI chr 9:3,503,328...4,017,131
Ensembl chr 9:3,513,623...4,016,913 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO
IEA		 (PMID:20660291)
GO_REF:0000107		 RGD
Ensembl		 PMID:20660291 GO_REF:0000107 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Wnt3a Wnt family member 3A involved_in ISO (PMID:16890161) RGD PMID:16890161 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
postsynaptic neurotransmitter receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap2b1 adaptor related protein complex 2 subunit beta 1 involved_in ISO
EXP
IDA
NAS
IMP		 (MGI:5819335|PMID:24217640)
PMID:17289840		 RGD PMID:24217640 PMID:17289840 PMID:17289840 PMID:17289840 PMID:17289840 MGI:5819335, RGD:13432317, RGD:13432317, RGD:13432317, RGD:13432317 NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013 		JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 involved_in IMP
IDA
ISO
EXP		 PMID:17289840
(MGI:5819335|PMID:24217640)		 RGD PMID:24217640 PMID:17289840 PMID:17289840 PMID:17289840 MGI:5819335, RGD:13432317, RGD:13432317, RGD:13432317 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140 		JBrowse link
G Ap2s1 adaptor related protein complex 2 subunit sigma 1 involved_in IMP
NAS
IDA
EXP		 PMID:17289840 SynGO PMID:17289840 PMID:17289840 PMID:17289840 PMID:17289840 RGD:13432317, RGD:13432317, RGD:13432317, RGD:13432317 NCBI chr 1:77,417,496...77,428,903
Ensembl chr 1:77,417,477...77,428,905 		JBrowse link
G Caly calcyon neuron-specific vesicular protein involved_in ISO (MGI:3836481|PMID:19120439) RGD PMID:19120439 MGI:3836481 NCBI chr 1:194,862,671...194,873,861
Ensembl chr 1:194,862,672...194,873,551 		JBrowse link
G Dnm3 dynamin 3 involved_in IMP PMID:17880892 SynGO PMID:17880892 RGD:8553820 NCBI chr13:74,359,043...74,838,135
Ensembl chr13:74,359,213...74,838,108 		JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 involved_in IDA
IEP
IMP		 PMID:25023288 SynGO PMID:25023288 PMID:25023288 PMID:25023288 RGD:13702241, RGD:13702241, RGD:13702241 NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221 		JBrowse link
G Myo6 myosin VI involved_in ISO (MGI:3527915|PMID:15657400) RGD PMID:15657400 MGI:3527915 NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family involved_in IMP
IDA		 PMID:15629704 SynGO PMID:15629704 PMID:15629704 RGD:155230721, RGD:155230721 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873 		JBrowse link
G Rab5al1 Rab5a, member RAS oncogene family-like 1 involved_in IMP
IDA		 PMID:15629704 SynGO PMID:15629704 PMID:15629704 RGD:155230721, RGD:155230721 NCBI chr14:68,332,360...68,334,470
Ensembl chr14:68,332,558...68,333,205 		JBrowse link
G Sh3glb2 SH3 domain-containing GRB2-like endophilin B2 involved_in IDA
IEP
IMP		 PMID:26776730 SynGO PMID:26776730 PMID:26776730 PMID:26776730 RGD:11564596, RGD:11564596, RGD:11564596 NCBI chr 3:13,616,936...13,631,785
Ensembl chr 3:13,616,938...13,631,757 		JBrowse link
G Synj1 synaptojanin 1 involved_in ISO (MGI:5819348|PMID:18987319) RGD PMID:18987319 MGI:5819348 NCBI chr11:30,192,629...30,269,277
Ensembl chr11:30,192,629...30,269,220 		JBrowse link
prostaglandin receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:15937517 RGD:10043344 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
receptor internalization involved in canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in ISO (PMID:16890161) RGD PMID:16890161 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family involved_in ISO (PMID:16890161) RGD PMID:16890161 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873 		JBrowse link
G Scyl2 SCY1 like pseudokinase 2 involved_in ISO (PMID:19643732) RGD PMID:19643732 NCBI chr 7:24,064,404...24,117,338
Ensembl chr 7:24,064,404...24,117,305 		JBrowse link
regulation of postsynaptic neurotransmitter receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap5 A-kinase anchoring protein 5 involved_in IMP
IDA		 PMID:19169250 SynGO PMID:19169250 PMID:19169250 RGD:2313185, RGD:2313185 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein involved_in ISO (MGI:6189470|PMID:17088211) RGD PMID:17088211 MGI:6189470 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Atad1 ATPase family, AAA domain containing 1 involved_in ISO (MGI:5050342|PMID:21496646) RGD PMID:21496646 MGI:5050342 NCBI chr 1:230,544,227...230,610,524
Ensembl chr 1:230,544,047...230,596,548 		JBrowse link
G Drd3 dopamine receptor D3 involved_in EXP
IEP
IDA		 PMID:16510729 SynGO PMID:16510729 PMID:16510729 PMID:16510729 RGD:13702467, RGD:13702467, RGD:13702467 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Drd4 dopamine receptor D4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3826939|PMID:18832154)		 Ensembl
RGD		 PMID:18832154 GO_REF:0000107 MGI:3826939 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Efnb2 ephrin B2 involved_in ISO (MGI:3814755|PMID:19160501) RGD PMID:19160501 MGI:3814755 NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391 		JBrowse link
G Gsg1l GSG1-like involved_in ISO (MGI:6189390|PMID:26932439) RGD PMID:26932439 MGI:6189390 NCBI chr 1:180,440,403...180,654,430
Ensembl chr 1:180,442,630...180,654,134 		JBrowse link
G Hap1 huntingtin-associated protein 1 involved_in IDA
IEP
IMP		 PMID:15310851 SynGO PMID:15310851 PMID:15310851 PMID:15310851 RGD:13702182, RGD:13702182, RGD:13702182 NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126 		JBrowse link
G Hip1 huntingtin interacting protein 1 involved_in ISO (MGI:2667266|PMID:12839988) RGD PMID:12839988 MGI:2667266 NCBI chr12:21,133,319...21,267,796
Ensembl chr12:21,133,406...21,267,725 		JBrowse link
G Hpca hippocalcin involved_in IMP
IDA		 PMID:20852624 SynGO PMID:20852624 PMID:20852624 RGD:13702412, RGD:13702412 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841 		JBrowse link
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 involved_in ISO (MGI:4821212|PMID:20547133) RGD PMID:20547133 MGI:4821212 NCBI chr 4:123,168,719...123,488,300
Ensembl chr 4:123,168,719...123,488,172 		JBrowse link
G Itgb3 integrin subunit beta 3 involved_in ISO
IEA		 (PMID:18549786)
GO_REF:0000107		 RGD
Ensembl		 PMID:18549786 GO_REF:0000107 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 involved_in IMP
IEP
EXP
IDA		 PMID:25996636 SynGO PMID:25996636 PMID:25996636 PMID:25996636 PMID:25996636 RGD:155230734, RGD:155230734, RGD:155230734, RGD:155230734 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase involved_in IDA
IEP
IMP		 PMID:21148011 SynGO PMID:21148011 PMID:21148011 PMID:21148011 RGD:13702142, RGD:13702142, RGD:13702142 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951 		JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (PMID:16221846) RGD PMID:16221846 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Numb NUMB, endocytic adaptor protein involved_in ISO
IEA		 (MGI:5705662|PMID:26621723)
GO_REF:0000107		 RGD
Ensembl		 PMID:26621723 GO_REF:0000107 MGI:5705662 NCBI chr 6:103,431,400...103,553,422
Ensembl chr 6:103,431,400...103,553,354 		JBrowse link
G Ophn1 oligophrenin 1 involved_in ISO (PMID:24966368) RGD PMID:24966368 NCBI chr  X:63,599,746...63,976,678
Ensembl chr  X:63,603,042...63,976,633 		JBrowse link
G Pacsin1 protein kinase C and casein kinase substrate in neurons 1 involved_in IDA
IMP		 PMID:16617342
PMID:23918399		 SynGO PMID:16617342 PMID:23918399 PMID:16617342 PMID:23918399 RGD:13702454, RGD:13702399, RGD:13702454, RGD:13702399 NCBI chr20:5,718,134...5,768,064
Ensembl chr20:5,719,857...5,765,313 		JBrowse link
G Pick1 protein interacting with PRKCA 1 involved_in IMP
IEP
IDA		 PMID:28855251 SynGO PMID:28855251 PMID:28855251 PMID:28855251 RGD:13702248, RGD:13702248, RGD:13702248 NCBI chr 7:110,796,623...110,816,850
Ensembl chr 7:110,797,117...110,816,848 		JBrowse link
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase type 1 gamma involved_in ISO (MGI:6189392|PMID:22243752) RGD PMID:22243752 MGI:6189392 NCBI chr 7:8,397,406...8,426,030
Ensembl chr 7:8,397,406...8,425,988 		JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha involved_in ISO (MGI:2154682|PMID:11733061) RGD PMID:11733061 MGI:2154682 NCBI chr14:91,556,743...91,606,230
Ensembl chr14:91,604,121...91,606,907 		JBrowse link
G Rala RAS like proto-oncogene A involved_in EXP
IMP
IDA		 PMID:19823667 SynGO PMID:19823667 PMID:19823667 PMID:19823667 RGD:2324918, RGD:2324918, RGD:2324918 NCBI chr17:47,092,139...47,145,192
Ensembl chr17:47,092,207...47,144,063 		JBrowse link
G Rnf216 ring finger protein 216 involved_in IMP
IDA		 PMID:24945773 SynGO PMID:24945773 PMID:24945773 RGD:11553202, RGD:11553202 NCBI chr12:11,454,752...11,576,305
Ensembl chr12:11,454,797...11,576,304 		JBrowse link
G Scrib scribble planar cell polarity protein involved_in IDA
IMP		 PMID:25310985 SynGO PMID:25310985 PMID:25310985 RGD:12050130, RGD:12050130 NCBI chr 7:107,759,343...107,782,364
Ensembl chr 7:107,759,343...107,782,331 		JBrowse link
G Sirt2 sirtuin 2 involved_in IDA
IEP
IMP
EXP		 PMID:28793258 SynGO PMID:28793258 PMID:28793258 PMID:28793258 PMID:28793258 RGD:13702139, RGD:13702139, RGD:13702139, RGD:13702139 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Syne1 spectrin repeat containing nuclear envelope protein 1 IMP RGD PMID:24191017 RGD:13209020 NCBI chr 1:41,512,146...41,983,382
Ensembl chr 1:41,512,030...41,983,322 		JBrowse link
G Synj1 synaptojanin 1 involved_in ISO (MGI:5819348|PMID:18987319) RGD PMID:18987319 MGI:5819348 NCBI chr11:30,192,629...30,269,277
Ensembl chr11:30,192,629...30,269,220 		JBrowse link
G Tspan7 tetraspanin 7 involved_in IDA
IMP		 PMID:22445342 SynGO PMID:22445342 PMID:22445342 RGD:11068824, RGD:11068824 NCBI chr  X:12,208,783...12,306,160
Ensembl chr  X:12,208,783...12,306,131 		JBrowse link
G Usp46 ubiquitin specific peptidase 46 involved_in IMP
IEP
IDA		 PMID:26077708 SynGO PMID:26077708 PMID:26077708 PMID:26077708 RGD:11056935, RGD:11056935, RGD:11056935 NCBI chr14:34,150,055...34,219,227
Ensembl chr14:34,150,004...34,219,227 		JBrowse link
G Vac14 VAC14 component of PIKFYVE complex involved_in ISO (MGI:5441640|PMID:22842785) RGD PMID:22842785 MGI:5441640 NCBI chr19:38,590,569...38,691,911
Ensembl chr19:38,590,569...38,691,909 		JBrowse link
regulation of receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf1 ADP-ribosylation factor 1 involved_in IDA PMID:23889934 UniProt PMID:23889934 RGD:8553918 NCBI chr10:43,997,983...44,014,543
Ensembl chr10:43,997,986...44,014,434 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:17804805) RGD PMID:17804805 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Flot1 flotillin 1 involved_in ISO
IBA		 (PMID:21399631)
(MGI:5634885|PMID:21399631)
PMID:21873635		 RGD PMID:21399631 PMID:21873635 MGI:5634885, RGD:13792537 NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978 		JBrowse link
G Mkln1 muskelin 1 involved_in IMP PMID:25579817 UniProt PMID:25579817 RGD:13702173 NCBI chr 4:59,815,912...60,124,047
Ensembl chr 4:60,002,464...60,123,993 		JBrowse link
G Napb NSF attachment protein beta involved_in IDA PMID:11931741 UniProt PMID:11931741 RGD:633462 NCBI chr 3:136,132,248...136,179,225
Ensembl chr 3:136,133,428...136,179,345 		JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase involved_in IDA PMID:11931741 UniProt PMID:11931741 RGD:633462 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386 		JBrowse link
G Rspo1 R-spondin 1 involved_in ISO (PMID:17804805) RGD PMID:17804805 NCBI chr 5:137,251,629...137,273,273
Ensembl chr 5:137,251,659...137,272,933 		JBrowse link
G Sh3gl2 SH3 domain containing GRB2 like 2, endophilin A1 acts_upstream_of_or_within ISO (MGI:3624069|PMID:16164598) RGD PMID:16164598 MGI:3624069 NCBI chr 5:99,653,189...99,827,500
Ensembl chr 5:99,653,152...100,113,843 		JBrowse link
G Synj2bp synaptojanin 2 binding protein NOT|involved_in ISO (MGI:3623710|PMID:16648306) RGD PMID:16648306 MGI:3623710 NCBI chr 6:101,189,714...101,227,400
Ensembl chr 6:101,189,714...101,227,406 		JBrowse link
regulation of signal transduction by receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 acts_upstream_of_or_within ISO (PMID:20472890) RGD PMID:20472890 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19903
    localization 5654
      establishment of localization 4989
        transport 4824
          vesicle-mediated transport 1661
            endocytosis 649
              receptor-mediated endocytosis 279
                receptor internalization 157
                  B cell receptor internalization + 0
                  G protein-coupled receptor internalization + 20
                  Wnt receptor internalization + 0
                  insulin receptor internalization + 3
                  negative regulation of receptor internalization + 18
                  neurotransmitter receptor internalization + 47
                  positive regulation of receptor internalization + 35
                  receptor internalization involved in canonical Wnt signaling pathway 3
                  regulation of receptor internalization + 87
                  regulation of signal transduction by receptor internalization + 1
paths to the root