ONTOLOGY REPORT - ANNOTATIONS
Term: DNA integrity checkpoint signaling
Accession: GO:0031570
browse the term
Definition: A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes.
Synonyms: exact_synonym: DNA integrity checkpoint; signal transduction involved in DNA integrity checkpoint
alt_id: GO:0072401
G
Gcna
predicted gene, 52429
acts_upstream_of_or_within
IMP
(MGI:6390726|PMID:31839538)
MGI
PMID:31839538
MGI:6390726
NCBI chr X:100,739,442...100,749,805
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Atm
ataxia telangiectasia mutated
acts_upstream_of_or_within involved_in
IMP ISO IBA
(MGI:2679752|PMID:12937170) (MGI:6201960|PMID:21873635)
MGI GO_Central
PMID:12937170 PMID:21873635
GO_REF:0000096 MGI:2679752 MGI:4834177 MGI:6201960
NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040
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Atr
ataxia telangiectasia and Rad3 related
acts_upstream_of_or_within involved_in
IMP ISO IBA
(MGI:2679752|PMID:12937170) (MGI:6201960|PMID:21873635)
MGI GO_Central
PMID:12937170 PMID:21873635
GO_REF:0000096 MGI:2679752 MGI:4834177 MGI:6201960
NCBI chr 9:95,739,650...95,834,813
Ensembl chr 9:95,739,650...95,833,834
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Atrip
ATR interacting protein
involved_in
IEA
UniProt
GO_REF:0000002 MGI:2152098
NCBI chr 9:108,888,815...108,903,192
Ensembl chr 9:108,887,001...108,903,192
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Cdc5l
cell division cycle 5-like (S. pombe)
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr17:45,702,809...45,744,633
Ensembl chr17:45,702,810...45,744,663
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Chek1
checkpoint kinase 1
acts_upstream_of_or_within involved_in
IMP IDA ISO
(MGI:1860049|PMID:10859164) (MGI:2449744|PMID:12529385)
MGI
PMID:10859164 PMID:12529385
GO_REF:0000096 MGI:1860049 MGI:2449744 MGI:4834177
NCBI chr 9:36,619,778...36,637,954
Ensembl chr 9:36,619,778...36,638,361
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Chek2
checkpoint kinase 2
involved_in
ISO
RGD MGI
PMID:10435585
GO_REF:0000096 MGI:4417868 RGD:633752
NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011
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Clock
circadian locomotor output cycles kaput
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 5:76,357,715...76,452,675
Ensembl chr 5:76,357,715...76,452,639
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Clspn
claspin
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 4:126,450,738...126,488,326
Ensembl chr 4:126,450,728...126,487,696
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Donson
downstream neighbor of SON
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr16:91,463,744...91,485,702
Ensembl chr16:91,473,696...91,485,658
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Dot1l
DOT1-like, histone H3 methyltransferase (S. cerevisiae)
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr10:80,590,935...80,631,295
Ensembl chr10:80,591,040...80,631,295
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Dtx3l
deltex 3-like, E3 ubiquitin ligase
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr16:35,746,885...35,759,397
Ensembl chr16:35,746,881...35,759,521
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E2f1
E2F transcription factor 1
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812
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Eif2ak4
eukaryotic translation initiation factor 2 alpha kinase 4
involved_in
IEA
UniProt
GO_REF:0000002 MGI:2152098
NCBI chr 2:118,219,065...118,305,715
Ensembl chr 2:118,219,099...118,305,715
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Ercc6
excision repair cross-complementing rodent repair deficiency, complementation group 6
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr14:32,235,248...32,302,947
Ensembl chr14:32,235,478...32,302,947
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H2ax
H2A.X variant histone
involved_in NOT|acts_upstream_of_or_within
ISO IMP
(PMID:17974976) (MGI:2179182|PMID:11934988)
UniProt MGI
PMID:11934988 PMID:17974976
MGI:2179182
NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
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Hinfp
histone H4 transcription factor
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 9:44,201,509...44,217,003
Ensembl chr 9:44,203,737...44,216,968
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Hus1
HUS1 checkpoint clamp component
acts_upstream_of_or_within involved_in
IMP ISO
(MGI:2449744|PMID:12529385)
MGI
PMID:12529385
GO_REF:0000096 MGI:2449744 MGI:4834177
NCBI chr11:8,943,137...8,961,240
Ensembl chr11:8,943,137...8,961,191
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Hus1b
HUS1 checkpoint clamp component B
involved_in
IEA
UniProt
GO_REF:0000002 MGI:2152098
NCBI chr13:31,130,559...31,131,744
Ensembl chr13:31,130,556...31,131,742
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Ints7
integrator complex subunit 7
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 1:191,307,652...191,355,802
Ensembl chr 1:191,307,748...191,355,800
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Map3k20
mitogen-activated protein kinase kinase kinase 20
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 2:72,115,970...72,272,954
Ensembl chr 2:72,115,981...72,272,954
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Mapk14
mitogen-activated protein kinase 14
acts_upstream_of_or_within
IMP
(MGI:2679752|PMID:12937170)
MGI
PMID:12937170
MGI:2679752
NCBI chr17:28,910,243...28,967,379
Ensembl chr17:28,910,303...28,967,380
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Nbn
nibrin
acts_upstream_of_or_within
ISO
(MGI:2449744|PMID:12529385)
MGI
PMID:12529385
MGI:2449744
NCBI chr 4:15,955,388...15,992,589
Ensembl chr 4:15,957,925...15,992,589
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Parp9
poly (ADP-ribose) polymerase family, member 9
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr16:35,758,840...35,792,991
Ensembl chr16:35,758,840...35,792,975
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Prpf19
pre-mRNA processing factor 19
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr19:10,872,595...10,886,923
Ensembl chr19:10,872,595...10,886,923
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Ptpn11
protein tyrosine phosphatase, non-receptor type 11
acts_upstream_of_or_within
IMP
(MGI:2679752|PMID:12937170)
MGI
PMID:12937170
MGI:2679752
NCBI chr 5:121,268,596...121,329,460
Ensembl chr 5:121,268,596...121,329,460
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Rad1
RAD1 checkpoint DNA exonuclease
involved_in
ISO IBA
(MGI:6201960|PMID:21873635)
MGI GO_Central
PMID:21873635
GO_REF:0000096 MGI:4834177 MGI:6201960
NCBI chr15:10,486,104...10,499,149
Ensembl chr15:10,486,104...10,499,149
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Rad17
RAD17 checkpoint clamp loader component
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr13:100,753,672...100,787,569
Ensembl chr13:100,753,672...100,787,559
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Rad9a
RAD9 checkpoint clamp component A
involved_in acts_upstream_of_or_within
ISO ISS
(MGI:1927035|PMID:11058134)
MGI
PMID:11058134
GO_REF:0000096 MGI:1927035 MGI:4834177
NCBI chr19:4,245,195...4,251,710
Ensembl chr19:4,245,195...4,251,661
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Rad9b
RAD9 checkpoint clamp component B
involved_in
IEA
UniProt
GO_REF:0000002 MGI:2152098
NCBI chr 5:122,461,286...122,492,297
Ensembl chr 5:122,461,286...122,492,296
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Rhno1
RAD9-HUS1-RAD1 interacting nuclear orphan 1
involved_in
IBA ISO
(MGI:6201960|PMID:21873635)
GO_Central MGI
PMID:21873635
GO_REF:0000096 MGI:4834177 MGI:6201960
NCBI chr 6:128,333,962...128,339,876
Ensembl chr 6:128,333,963...128,339,874
G
Tipin
timeless interacting protein
acts_upstream_of_or_within
IMP
(MGI:3706226|PMID:17141802)
MGI
PMID:17141802
MGI:3706226
NCBI chr 9:64,188,776...64,212,704
Ensembl chr 9:64,188,863...64,212,706
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Tiprl
TIP41, TOR signalling pathway regulator-like (S. cerevisiae)
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 1:165,039,855...165,110,228
Ensembl chr 1:165,039,855...165,064,565
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Trex1
three prime repair exonuclease 1
acts_upstream_of_or_within
IMP
(MGI:3818783|PMID:18045533)
MGI
PMID:18045533
MGI:3818783
NCBI chr 9:108,887,000...108,888,791
Ensembl chr 9:108,887,001...108,888,802
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Trp53bp1
transformation related protein 53 binding protein 1
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr 2:121,025,316...121,126,830
Ensembl chr 2:121,023,762...121,101,888
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Ufl1
UFM1 specific ligase 1
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 4:25,247,149...25,281,821
Ensembl chr 4:25,248,600...25,281,821
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Usp28
ubiquitin specific peptidase 28
involved_in
IBA ISO
(MGI:6201960|PMID:21873635)
GO_Central MGI
PMID:21873635
GO_REF:0000096 MGI:4834177 MGI:6201960
NCBI chr 9:48,896,577...48,953,817
Ensembl chr 9:48,896,675...48,953,817
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Casp2
caspase 2
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 6:42,241,841...42,259,442
Ensembl chr 6:42,241,919...42,259,442
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Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
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Cradd
CASP2 and RIPK1 domain containing adaptor with death domain
involved_in
ISO IBA
(MGI:6201960|PMID:21873635)
MGI GO_Central
PMID:21873635
GO_REF:0000096 MGI:4834177 MGI:6201960
NCBI chr10:95,010,601...95,160,000
Ensembl chr10:95,010,608...95,159,995
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Mdm2
transformed mouse 3T3 cell double minute 2
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663
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Muc1
mucin 1, transmembrane
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688
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Pcbp4
poly(rC) binding protein 4
involved_in
ISO
(PMID:10891498)
UniProt
PMID:10891498
NCBI chr 9:106,330,181...106,341,211
Ensembl chr 9:106,330,490...106,341,211
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Pidd1
p53 induced death domain protein 1
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 7:141,018,026...141,027,477
Ensembl chr 7:141,018,026...141,023,938
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Pml
promyelocytic leukemia
involved_in
IMP
(MGI:3580934|PMID:15626733)
UniProt
PMID:15626733
MGI:3580934
NCBI chr 9:58,124,462...58,157,077
Ensembl chr 9:58,125,359...58,157,069
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Ppp2r5c
protein phosphatase 2, regulatory subunit B', gamma
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr12:110,413,532...110,549,509
Ensembl chr12:110,413,554...110,549,496
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Prap1
proline-rich acidic protein 1
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 7:139,673,309...139,677,116
Ensembl chr 7:139,673,308...139,677,113
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Ptprv
protein tyrosine phosphatase, receptor type, V
acts_upstream_of_or_within
IGI
(MGI:3589512|PMID:16107883)
MGI
PMID:16107883
MGI:3589512
NCBI chr 1:135,036,236...135,060,313
Ensembl chr 1:135,036,235...135,060,332
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Rbm38
RNA binding motif protein 38
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 2:172,863,680...172,876,527
Ensembl chr 2:172,862,291...172,876,527
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Rpl26
ribosomal protein L26
involved_in
IDA ISO
(MGI:5882892|PMID:16213212)
CAFA MGI
PMID:16213212
GO_REF:0000096 MGI:4834177 MGI:5882892
NCBI chr11:68,792,392...68,795,360
Ensembl chr11:68,792,409...68,797,815
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Trp53
transformation related protein 53
involved_in acts_upstream_of_or_within
ISO IGI
(MGI:3589512|PMID:16107883)
MGI
PMID:16107883
GO_REF:0000096 MGI:3589512 MGI:4834177
NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
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Cdt1
chromatin licensing and DNA replication factor 1
involved_in
IBA ISO IDA
(MGI:6201960|PMID:21873635) (MGI:2388867|PMID:12192004)
GO_Central MGI UniProt
PMID:12192004 PMID:21873635
GO_REF:0000096 MGI:2388867 MGI:4834177 MGI:6201960
NCBI chr 8:123,294,754...123,299,869
Ensembl chr 8:123,294,754...123,300,293
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Clspn
claspin
acts_upstream_of_or_within
ISO
(PMID:16123041)
MGI UniProt
PMID:16123041
GO_REF:0000008 MGI:2154458
NCBI chr 4:126,450,738...126,488,326
Ensembl chr 4:126,450,728...126,487,696
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Dna2
DNA replication helicase/nuclease 2
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr10:62,782,762...62,809,967
Ensembl chr10:62,782,805...62,809,964
G
Rad9a
RAD9 checkpoint clamp component A
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr19:4,245,195...4,251,710
Ensembl chr19:4,245,195...4,251,661
G
Rad9b
RAD9 checkpoint clamp component B
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr 5:122,461,286...122,492,297
Ensembl chr 5:122,461,286...122,492,296
G
Timeless
timeless circadian clock 1
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr10:128,067,932...128,088,810
Ensembl chr10:128,067,934...128,088,810
G
Tipin
timeless interacting protein
involved_in
IBA ISO
(MGI:6201960|PMID:21873635)
GO_Central MGI
PMID:21873635
GO_REF:0000096 MGI:4834177 MGI:6201960
NCBI chr 9:64,188,776...64,212,704
Ensembl chr 9:64,188,863...64,212,706
G
Hus1
HUS1 checkpoint clamp component
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr11:8,943,137...8,961,240
Ensembl chr11:8,943,137...8,961,191
G
Hus1b
HUS1 checkpoint clamp component B
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr13:31,130,559...31,131,744
Ensembl chr13:31,130,556...31,131,742
G
Chek2
checkpoint kinase 2
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011
G
Stk33
serine/threonine kinase 33
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr 7:108,878,270...109,038,375
Ensembl chr 7:108,878,430...109,038,288
G
Zfp830
zinc finger protein 830
involved_in acts_upstream_of_or_within
IBA IMP
(MGI:6201960|PMID:21873635) (MGI:5428139|PMID:23213458)
GO_Central MGI
PMID:21873635 PMID:23213458
MGI:5428139 MGI:6201960
NCBI chr11:82,655,171...82,658,448
Ensembl chr11:82,655,171...82,656,761
G
Setmar
SET domain without mariner transposase fusion
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 6:108,042,006...108,054,088
Ensembl chr 6:108,042,006...108,054,083
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Cdc6
cell division cycle 6
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr11:98,798,627...98,814,768
Ensembl chr11:98,798,627...98,814,766
G
Clspn
claspin
involved_in
ISO IBA
(MGI:6201960|PMID:21873635)
MGI GO_Central
PMID:21873635
GO_REF:0000096 MGI:4834177 MGI:6201960
NCBI chr 4:126,450,738...126,488,326
Ensembl chr 4:126,450,728...126,487,696
G
Hus1
HUS1 checkpoint clamp component
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr11:8,943,137...8,961,240
Ensembl chr11:8,943,137...8,961,191
G
Hus1b
HUS1 checkpoint clamp component B
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr13:31,130,559...31,131,744
Ensembl chr13:31,130,556...31,131,742
G
Nae1
NEDD8 activating enzyme E1 subunit 1
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 8:105,237,660...105,261,269
Ensembl chr 8:105,237,660...105,261,269
G
Orc1
origin recognition complex, subunit 1
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr 4:108,436,651...108,472,030
Ensembl chr 4:108,436,620...108,472,030
G
Rad17
RAD17 checkpoint clamp loader component
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr13:100,753,672...100,787,569
Ensembl chr13:100,753,672...100,787,559
G
Ticrr
TOPBP1-interacting checkpoint and replication regulator
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr 7:79,309,944...79,347,896
Ensembl chr 7:79,309,944...79,347,896
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Topbp1
topoisomerase (DNA) II binding protein 1
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr 9:103,182,351...103,227,627
Ensembl chr 9:103,182,414...103,227,627
G
Zfp830
zinc finger protein 830
involved_in
IMP IBA
(MGI:4950701|PMID:21191184) (MGI:6201960|PMID:21873635)
UniProt GO_Central
PMID:21191184 PMID:21873635
MGI:4950701 MGI:6201960
NCBI chr11:82,655,171...82,658,448
Ensembl chr11:82,655,171...82,656,761
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Ccnd1
cyclin D1
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
G
Dgkz
diacylglycerol kinase zeta
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 2:91,763,167...91,806,788
Ensembl chr 2:91,763,169...91,806,209
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Fbxo31
F-box protein 31
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 8:122,276,182...122,305,607
Ensembl chr 8:122,276,179...122,305,545
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Gigyf2
GRB10 interacting GYF protein 2
acts_upstream_of_or_within
IMP
(MGI:4366664|PMID:19744960)
MGI
PMID:19744960
MGI:4366664
NCBI chr 1:87,254,653...87,378,532
Ensembl chr 1:87,254,720...87,378,518
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Prkdc
protein kinase, DNA activated, catalytic polypeptide
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099
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Ptprv
protein tyrosine phosphatase, receptor type, V
acts_upstream_of_or_within
IMP
(MGI:3589512|PMID:16107883)
MGI
PMID:16107883
MGI:3589512
NCBI chr 1:135,036,236...135,060,313
Ensembl chr 1:135,036,235...135,060,332
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Rfwd3
ring finger and WD repeat domain 3
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 8:111,997,576...112,026,854
Ensembl chr 8:111,997,576...112,026,854
G
Rpa2
replication protein A2
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 4:132,495,671...132,506,057
Ensembl chr 4:132,495,643...132,506,063
G
Rps27l
ribosomal protein S27-like
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 9:66,851,906...66,856,804
Ensembl chr 9:66,853,368...66,856,798
G
Sde2
SDE2 telomere maintenance homolog (S. pombe)
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 1:180,678,716...180,695,678
Ensembl chr 1:180,678,692...180,695,678
G
Trex1
three prime repair exonuclease 1
acts_upstream_of_or_within
IMP
(MGI:3818783|PMID:18045533) (MGI:5562498|PMID:23993650)
MGI
PMID:18045533 PMID:23993650
MGI:3818783 MGI:5562498
NCBI chr 9:108,887,000...108,888,791
Ensembl chr 9:108,887,001...108,888,802
G
Trp53
transformation related protein 53
acts_upstream_of_or_within involved_in
IMP ISO
(MGI:3589512|PMID:16107883)
MGI
PMID:16107883
GO_REF:0000096 MGI:3589512 MGI:4834177
NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
G
Wac
WW domain containing adaptor with coiled-coil
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr18:7,868,614...7,929,028
Ensembl chr18:7,868,832...7,929,028
G
Abraxas1
BRCA1 A complex subunit
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 5:100,952,668...100,993,430
Ensembl chr 5:100,953,058...100,968,831
G
Atm
ataxia telangiectasia mutated
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040
G
Babam1
BRISC and BRCA1 A complex member 1
involved_in
ISO IBA
(MGI:6201960|PMID:21873635)
MGI GO_Central
PMID:21873635
GO_REF:0000096 MGI:4834177 MGI:6201960
NCBI chr 8:71,848,809...71,857,416
Ensembl chr 8:71,849,505...71,857,263
G
Babam2
BRISC and BRCA1 A complex member 2
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 5:31,855,394...32,242,083
Ensembl chr 5:31,855,028...32,242,306
G
Blm
Bloom syndrome, RecQ like helicase
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 7:80,104,741...80,184,896
Ensembl chr 7:80,104,481...80,184,867
G
Brca1
breast cancer 1, early onset
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781
G
Brcc3
BRCA1/BRCA2-containing complex, subunit 3
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr X:74,460,234...74,499,307
Ensembl chr X:74,460,234...74,497,607
G
Brcc3dc
BRCA1/BRCA2-containing complex, subunit 3, domain containing
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr10:108,534,905...108,536,021
Ensembl chr10:108,534,625...108,536,021
G
Brsk1
BR serine/threonine kinase 1
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 7:4,693,635...4,718,996
Ensembl chr 7:4,693,603...4,718,996
G
Ccng1
cyclin G1
involved_in
ISO
RGD MGI
PMID:9464250
GO_REF:0000096 MGI:4417868 RGD:2316029
NCBI chr11:40,639,379...40,646,155
Ensembl chr11:40,639,379...40,646,138
G
Cdc14b
CDC14 cell division cycle 14B
involved_in
ISO
(PMID:18662541)
UniProt
PMID:18662541
NCBI chr13:64,337,085...64,423,670
Ensembl chr13:64,337,082...64,423,104
G
Cdk1
cyclin-dependent kinase 1
involved_in acts_upstream_of_or_within
IBA IDA
(MGI:6201960|PMID:21873635) (MGI:2679752|PMID:12937170)
GO_Central MGI
PMID:12937170 PMID:21873635
MGI:2679752 MGI:6201960
NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768
G
Cdk5rap3
CDK5 regulatory subunit associated protein 3
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr11:96,798,251...96,807,359
Ensembl chr11:96,798,252...96,807,322
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
G
Chek1
checkpoint kinase 1
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 9:36,619,778...36,637,954
Ensembl chr 9:36,619,778...36,638,361
G
Clspn
claspin
involved_in
ISO IBA
(MGI:6201960|PMID:21873635)
MGI GO_Central
PMID:21873635
GO_REF:0000096 MGI:4834177 MGI:6201960
NCBI chr 4:126,450,738...126,488,326
Ensembl chr 4:126,450,728...126,487,696
G
D7Ertd443e
DNA segment, Chr 7, ERATO Doi 443, expressed
involved_in
IDA
(MGI:4455105|PMID:20154723)
UniProt
PMID:20154723
MGI:4455105
NCBI chr 7:133,867,509...134,121,888
Ensembl chr 7:133,867,508...134,102,889
G
Donson
downstream neighbor of SON
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr16:91,463,744...91,485,702
Ensembl chr16:91,473,696...91,485,658
G
Dtl
denticleless E3 ubiquitin protein ligase
involved_in
ISO IBA
(MGI:6201960|PMID:21873635)
MGI GO_Central
PMID:21873635
GO_REF:0000096 MGI:4834177 MGI:6201960
NCBI chr 1:191,269,468...191,307,656
Ensembl chr 1:191,269,468...191,307,656
G
Foxn3
forkhead box N3
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr12:99,156,340...99,529,926
Ensembl chr12:99,156,337...99,529,841
G
Foxo4
forkhead box O4
acts_upstream_of_or_within
IDA
(MGI:2183145|PMID:12048180)
MGI
PMID:12048180
MGI:2183145
NCBI chr X:100,297,855...100,304,479
Ensembl chr X:100,298,134...100,304,479
G
Fzr1
fizzy and cell division cycle 20 related 1
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr10:81,202,713...81,214,204
Ensembl chr10:81,202,056...81,214,350
G
Hmga2
high mobility group AT-hook 2
involved_in
ISO
(PMID:16061642)
UniProt
PMID:16061642
NCBI chr10:120,197,173...120,312,374
Ensembl chr10:120,197,180...120,312,374
G
Ier3
immediate early response 3
acts_upstream_of_or_within
IMP
(MGI:5432078|PMID:20467439)
MGI
PMID:20467439
MGI:5432078
NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815
G
Mbd4
methyl-CpG binding domain protein 4
acts_upstream_of_or_within
IMP
(MGI:2682526|PMID:14614141)
MGI
PMID:14614141
MGI:2682526
NCBI chr 6:115,817,658...115,830,361
Ensembl chr 6:115,817,658...115,830,332
G
Mre11a
MRE11A homolog A, double strand break repair nuclease
involved_in acts_upstream_of_or_within
IBA IMP
(MGI:6201960|PMID:21873635) (MGI:2683367|PMID:14690604)
GO_Central MGI
PMID:14690604 PMID:21873635
MGI:2683367 MGI:6201960
NCBI chr 9:14,695,939...14,753,639
Ensembl chr 9:14,695,950...14,748,419
G
Mrnip
MRN complex interacting protein
involved_in
ISO IBA
(MGI:6201960|PMID:21873635)
MGI GO_Central
PMID:21873635
GO_REF:0000096 MGI:4834177 MGI:6201960
NCBI chr11:50,065,678...50,090,943
Ensembl chr11:50,065,271...50,090,942
G
Nbn
nibrin
involved_in acts_upstream_of_or_within
ISO IMP IBA
(MGI:3805397|PMID:18614044) (MGI:6201960|PMID:21873635)
MGI GO_Central
PMID:18614044 PMID:21873635
GO_REF:0000096 MGI:3805397 MGI:4834177 MGI:6201960
NCBI chr 4:15,955,388...15,992,589
Ensembl chr 4:15,957,925...15,992,589
G
Nop53
NOP53 ribosome biogenesis factor
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 7:15,671,760...15,680,033
Ensembl chr 7:15,670,108...15,679,999
G
Plk1
polo like kinase 1
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 7:121,758,658...121,769,107
Ensembl chr 7:121,758,662...121,769,096
G
Rint1
RAD50 interactor 1
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 5:23,992,700...24,028,582
Ensembl chr 5:23,992,709...24,025,367
G
Syf2
SYF2 homolog, RNA splicing factor (S. cerevisiae)
acts_upstream_of_or_within
IMP
(MGI:5435138|PMID:22448250)
MGI
PMID:22448250
MGI:5435138
NCBI chr 4:134,658,291...134,664,848
Ensembl chr 4:134,658,209...134,664,859
G
Taok1
TAO kinase 1
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr11:77,419,988...77,516,185
Ensembl chr11:77,419,988...77,498,641
G
Taok2
TAO kinase 2
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 7:126,464,848...126,485,468
Ensembl chr 7:126,464,850...126,483,875
G
Taok3
TAO kinase 3
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 5:117,258,180...117,413,283
Ensembl chr 5:117,258,194...117,413,284
G
Ticrr
TOPBP1-interacting checkpoint and replication regulator
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr 7:79,309,944...79,347,896
Ensembl chr 7:79,309,944...79,347,896
G
Topbp1
topoisomerase (DNA) II binding protein 1
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr 9:103,182,351...103,227,627
Ensembl chr 9:103,182,414...103,227,627
G
Trim39
tripartite motif-containing 39
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr17:36,569,764...36,582,896
Ensembl chr17:36,569,765...36,583,139
G
Uimc1
ubiquitin interaction motif containing 1
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr13:55,175,693...55,248,176
Ensembl chr13:55,175,693...55,248,113
G
Atf2
activating transcription factor 2
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 2:73,646,853...73,723,094
Ensembl chr 2:73,646,853...73,722,983
G
Chek2
checkpoint kinase 2
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011
G
Eme1
essential meiotic structure-specific endonuclease 1
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr11:94,535,798...94,544,611
Ensembl chr11:94,535,822...94,544,790
G
Eme2
essential meiotic structure-specific endonuclease subunit 2
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr17:25,111,126...25,114,061
Ensembl chr17:25,107,460...25,114,061
G
Fancd2
Fanconi anemia, complementation group D2
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr 6:113,508,622...113,573,981
Ensembl chr 6:113,508,643...113,573,978
G
Hus1
HUS1 checkpoint clamp component
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr11:8,943,137...8,961,240
Ensembl chr11:8,943,137...8,961,191
G
Hus1b
HUS1 checkpoint clamp component B
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr13:31,130,559...31,131,744
Ensembl chr13:31,130,556...31,131,742
G
Mre11a
MRE11A homolog A, double strand break repair nuclease
involved_in acts_upstream_of_or_within
IBA IMP
(MGI:6201960|PMID:21873635) (MGI:2683367|PMID:14690604), (MGI:3805397|PMID:18614044)
GO_Central MGI
PMID:14690604 PMID:18614044 PMID:21873635
MGI:2683367 MGI:3805397 MGI:6201960
NCBI chr 9:14,695,939...14,753,639
Ensembl chr 9:14,695,950...14,748,419
G
Msh2
mutS homolog 2
acts_upstream_of_or_within
IGI
(MGI:3512823|PMID:15533840)
MGI
PMID:15533840
MGI:3512823
NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141
G
Mus81
MUS81 structure-specific endonuclease subunit
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr19:5,532,589...5,538,461
Ensembl chr19:5,532,373...5,538,430
G
Nek11
NIMA (never in mitosis gene a)-related expressed kinase 11
involved_in
ISO IBA
(MGI:6201960|PMID:21873635)
MGI GO_Central
PMID:21873635
GO_REF:0000096 MGI:4834177 MGI:6201960
NCBI chr 9:105,039,355...105,272,723
Ensembl chr 9:105,039,355...105,272,723
G
Rad17
RAD17 checkpoint clamp loader component
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr13:100,753,672...100,787,569
Ensembl chr13:100,753,672...100,787,559
G
Rad9a
RAD9 checkpoint clamp component A
acts_upstream_of_or_within involved_in
IGI IBA
(MGI:1289930|PMID:9766521) (MGI:6201960|PMID:21873635)
MGI GO_Central
PMID:9766521 PMID:21873635
MGI:1289930 MGI:6201960
NCBI chr19:4,245,195...4,251,710
Ensembl chr19:4,245,195...4,251,661
G
Rad9b
RAD9 checkpoint clamp component B
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr 5:122,461,286...122,492,297
Ensembl chr 5:122,461,286...122,492,296
G
Tipin
timeless interacting protein
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 9:64,188,776...64,212,704
Ensembl chr 9:64,188,863...64,212,706
G
Xpc
xeroderma pigmentosum, complementation group C
acts_upstream_of_or_within
IGI
(MGI:3512823|PMID:15533840)
MGI
PMID:15533840
MGI:3512823
NCBI chr 6:91,466,287...91,492,870
Ensembl chr 6:91,466,287...91,492,870
G
Brd4
bromodomain containing 4
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr17:32,415,246...32,503,717
Ensembl chr17:32,415,248...32,503,696
G
Chek2
checkpoint kinase 2
involved_in
ISO
RGD MGI
PMID:20637979
GO_REF:0000096 MGI:4417868 RGD:10401658
NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011
G
Ddx39b
DEAD box helicase 39b
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr17:35,460,722...35,472,683
Ensembl chr17:35,460,722...35,472,683
G
Thoc1
THO complex 1
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr18:9,958,180...9,995,484
Ensembl chr18:9,957,906...9,995,489
G
Thoc5
THO complex 5
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr11:4,845,283...4,878,867
Ensembl chr11:4,845,320...4,878,867
G
Ppp1r10
protein phosphatase 1, regulatory subunit 10
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr17:36,227,404...36,243,175
Ensembl chr17:36,227,326...36,243,175
G
Ccar2
cell cycle activator and apoptosis regulator 2
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr14:70,375,617...70,391,272
Ensembl chr14:70,375,613...70,391,260
G
Map3k20
mitogen-activated protein kinase kinase kinase 20
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 2:72,115,970...72,272,954
Ensembl chr 2:72,115,981...72,272,954
G
Babam2
BRISC and BRCA1 A complex member 2
involved_in
NAS
(MGI:6867316|PMID:14636569)
ComplexPortal
PMID:14636569
MGI:6867316
NCBI chr 5:31,855,394...32,242,083
Ensembl chr 5:31,855,028...32,242,306
G
Bard1
BRCA1 associated RING domain 1
involved_in
NAS
(MGI:6867316|PMID:14636569)
ComplexPortal
PMID:14636569
MGI:6867316
NCBI chr 1:71,066,690...71,142,300
Ensembl chr 1:71,066,657...71,142,305
G
Brca1
breast cancer 1, early onset
involved_in
NAS
(MGI:6867316|PMID:14636569)
ComplexPortal
PMID:14636569
MGI:6867316
NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781
G
Brca2
breast cancer 2, early onset
involved_in
NAS
(MGI:6867316|PMID:14636569)
ComplexPortal
PMID:14636569
MGI:6867316
NCBI chr 5:150,445,759...150,493,612
Ensembl chr 5:150,446,095...150,493,794
G
Brcc3
BRCA1/BRCA2-containing complex, subunit 3
involved_in
NAS
(MGI:6867316|PMID:14636569)
ComplexPortal
PMID:14636569
MGI:6867316
NCBI chr X:74,460,234...74,499,307
Ensembl chr X:74,460,234...74,497,607
G
Cry1
cryptochrome 1 (photolyase-like)
involved_in
IDA
(MGI:5567851|PMID:24489120)
UniProt
PMID:24489120
MGI:5567851
NCBI chr10:84,967,564...85,020,918
Ensembl chr10:84,967,564...85,020,928
G
Cul4a
cullin 4A
acts_upstream_of_or_within
IMP
(MGI:3850765|PMID:19481525)
MGI
PMID:19481525
MGI:3850765
NCBI chr 8:13,155,623...13,197,940
Ensembl chr 8:13,155,621...13,197,940
G
Etaa1
Ewing tumor-associated antigen 1
involved_in
ISO IBA
(MGI:6201960|PMID:21873635)
MGI GO_Central
PMID:21873635
GO_REF:0000096 MGI:4834177 MGI:6201960
NCBI chr11:17,888,753...17,903,875
Ensembl chr11:17,888,756...17,903,875
G
Fbxo4
F-box protein 4
acts_upstream_of_or_within
IMP
(MGI:5299398|PMID:21911473)
MGI
PMID:21911473
MGI:5299398
NCBI chr15:3,993,046...4,009,055
Ensembl chr15:3,994,927...4,009,055
G
Fem1b
fem 1 homolog b
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 9:62,699,106...62,718,930
Ensembl chr 9:62,699,103...62,719,216
G
Nek1
NIMA (never in mitosis gene a)-related expressed kinase 1
involved_in
IMP
(MGI:5619475|PMID:18843199)
CACAO
PMID:18843199
MGI:5619475
NCBI chr 8:61,446,184...61,584,383
Ensembl chr 8:61,446,229...61,584,380
G
Rad51
RAD51 recombinase
involved_in
NAS
(MGI:6867316|PMID:14636569)
ComplexPortal
PMID:14636569
MGI:6867316
NCBI chr 2:118,943,295...118,966,554
Ensembl chr 2:118,943,274...118,977,926
G
Rfwd3
ring finger and WD repeat domain 3
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 8:111,997,576...112,026,854
Ensembl chr 8:111,997,576...112,026,854
G
Rnaseh2b
ribonuclease H2, subunit B
acts_upstream_of_or_within
IMP
(MGI:5435090|PMID:22802351)
MGI
PMID:22802351
MGI:5435090
NCBI chr14:62,569,517...62,610,445
Ensembl chr14:62,530,038...62,610,441
G
Rpa2
replication protein A2
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 4:132,495,671...132,506,057
Ensembl chr 4:132,495,643...132,506,063
G
Wdr76
WD repeat domain 76
involved_in
IBA
(MGI:6201960|PMID:21873635)
GO_Central
PMID:21873635
MGI:6201960
NCBI chr 2:121,337,204...121,375,341
Ensembl chr 2:121,337,204...121,375,341
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all