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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:brain-derived neurotrophic factor receptor signaling pathway
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Accession:GO:0031547 term browser browse the term
Definition:The series of molecular signals generated as a consequence of a brain-derived neurotrophic factor receptor binding to one of its physiological ligands.
Synonyms:exact_synonym: BDNF receptor signaling pathway;   BDNF signalling pathway;   brain-derived neurotrophic factor receptor signalling pathway
 never_in_taxon: NCBITaxon:4751 ! Fungi


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brain-derived neurotrophic factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 acts_upstream_of_or_within ISO MGI:4356167 (PMID:24342563) RGD PMID:24342563 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918 		JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 involved_in ISO (MGI:5426290|PMID:22586092) RGD PMID:22586092 MGI:5426290 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 involved_in IMP
ISO
IDA
IEA		 (MGI:5306304|PMID:16801538)
PMID:1645620
GO_REF:0000107
PMID:8627351
(PMID:15494731)		 RGD
Ensembl		 PMID:15494731 PMID:16801538 PMID:15654844 PMID:1645620 PMID:8627351 GO_REF:0000107 MGI:5306304, RGD:1626132, RGD:8554777, RGD:8554094 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in IMP PMID:17724123 UniProt PMID:17724123 RGD:8554481 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247 		JBrowse link
G Slc9a6 solute carrier family 9 member A6 acts_upstream_of_or_within ISO MGI:3604561 (PMID:24035762) RGD PMID:24035762 NCBI chr  X:134,430,677...134,486,747
Ensembl chr  X:134,420,756...134,485,375 		JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 involved_in ISO (MGI:5306304|PMID:16801538) RGD PMID:16801538 MGI:5306304 NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901 		JBrowse link
G Vps13a vacuolar protein sorting 13 homolog A acts_upstream_of_or_within ISO (PMID:37714309) RGD PMID:37714309 NCBI chr 1:213,901,999...214,128,638
Ensembl chr 1:213,901,999...214,128,555 		JBrowse link
negative regulation of brain-derived neurotrophic factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fstl4 follistatin-like 4 acts_upstream_of_or_within ISO (PMID:24573299) RGD PMID:24573299 NCBI chr10:36,911,422...37,344,545
Ensembl chr10:36,911,420...37,338,588 		JBrowse link
positive regulation of brain-derived neurotrophic factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc2a4 solute carrier family 2 member 4 acts_upstream_of_or_within IMP PMID:27881773 ARUK-UCL PMID:27881773 RGD:25671385 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    cellular process 18769
      signal transduction 7163
        cell surface receptor signaling pathway 2879
          enzyme-linked receptor protein signaling pathway 1052
            cell surface receptor protein tyrosine kinase signaling pathway 664
              brain-derived neurotrophic factor receptor signaling pathway 9
                negative regulation of brain-derived neurotrophic factor receptor signaling pathway + 1
                positive regulation of brain-derived neurotrophic factor receptor signaling pathway + 1
                regulation of brain-derived neurotrophic factor receptor signaling pathway + 2
Path 2
Term Annotations click to browse term
  biological_process 20292
    biological regulation 13633
      regulation of biological process 13220
        signaling 7729
          signal transduction 7163
            cell surface receptor signaling pathway 2879
              enzyme-linked receptor protein signaling pathway 1052
                cell surface receptor protein tyrosine kinase signaling pathway 664
                  brain-derived neurotrophic factor receptor signaling pathway 9
                    negative regulation of brain-derived neurotrophic factor receptor signaling pathway + 1
                    positive regulation of brain-derived neurotrophic factor receptor signaling pathway + 1
                    regulation of brain-derived neurotrophic factor receptor signaling pathway + 2
paths to the root