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ONTOLOGY REPORT - ANNOTATIONS


Term:heterochromatin assembly
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Accession:GO:0031507 term browser browse the term
Definition:An epigenetic gene silencing mechanism that involves the assembly of chromatin into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation.
Synonyms:exact_synonym: chromatin silencing;   chromatin-mediated silencing;   establishment of heterochromatin architecture;   heterochromatin formation;   transcriptional gene silencing
 narrow_synonym: establishment of heterochromatin architecture involved in chromatin silencing at centromere outer repeat region;   establishment of heterochromatin architecture involved in chromatin silencing at pericentric region;   heterochromatin assembly involved in chromatin silencing at centromere outer repeat region;   heterochromatin assembly involved in chromatin silencing at pericentric region;   heterochromatin formation involved in chromatin silencing at centromere outer repeat region;   heterochromatin formation involved in chromatin silencing at pericentric region
 broad_synonym: TGS;   heterochromatin maintenance
 related_synonym: establishment of chromatin silencing;   establishment of heterochromatic silencing;   heterochromatic silencing;   heterochromatin assembly involved in chromatin silencing;   heterochromatin formation involved in chromatin silencing
 alt_id: GO:0006342;   GO:0006343;   GO:0016440;   GO:0070869;   GO:1904497



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heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAHD1 bromo adjacent homology domain containing 1 involved_in IMP (PMID:19666599) UniProt PMID:19666599 NCBI chr15:40,439,757...40,468,237
Ensembl chr15:40,439,721...40,468,236
JBrowse link
G BAZ2A bromodomain adjacent to zinc finger domain 2A acts_upstream_of_or_within ISO (MGI:3653583|PMID:16678107)
(MGI:4462332|PMID:20168299)
MGI PMID:16678107 PMID:20168299 MGI:3653583 MGI:4462332 NCBI chr12:56,595,596...56,636,816
Ensembl chr12:56,595,596...56,636,816
JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:22,321,099...22,331,484
Ensembl chr10:22,321,099...22,331,484
JBrowse link
G COMMD3-BMI1 COMMD3-BMI1 readthrough involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:22,316,388...22,331,484
Ensembl chr10:22,316,388...22,329,542
JBrowse link
G CTBP1 C-terminal binding protein 1 involved_in IMP (PMID:21102443) BHF-UCL PMID:21102443 NCBI chr 4:1,211,444...1,250,355
Ensembl chr 4:1,211,445...1,249,953
JBrowse link
G EED embryonic ectoderm development involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:86,244,753...86,285,420
Ensembl chr11:86,244,753...86,278,813
JBrowse link
G EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit involved_in ISS (PMID:19026781) ARUK-UCL PMID:19026781 NCBI chr17:42,700,275...42,745,078
Ensembl chr17:42,700,275...42,745,049
JBrowse link
G H1-9P H1.9 linker histone, pseudogene involved_in IDA (PMID:12920187) UniProt PMID:12920187 NCBI chr17:50,171,428...50,172,476
Ensembl chr17:50,171,428...50,181,178
JBrowse link
G H2AB1 H2A.B variant histone 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:154,884,972...154,885,558
Ensembl chr  X:154,884,972...154,885,558
JBrowse link
G H2AB2 H2A.B variant histone 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:155,380,709...155,381,299
Ensembl chr  X:155,380,709...155,381,299
JBrowse link
G H2AB3 H2A.B variant histone 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:155,459,415...155,460,005
Ensembl chr  X:155,459,415...155,460,005
JBrowse link
G H2AC1 H2A clustered histone 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:25,726,063...25,726,562
Ensembl chr 6:25,726,063...25,726,562
JBrowse link
G H2AC11 H2A clustered histone 11 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:27,133,043...27,133,535
Ensembl chr 6:27,133,042...27,135,291
JBrowse link
G H2AC12 H2A clustered histone 12 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:27,147,106...27,147,562
Ensembl chr 6:27,147,106...27,147,562
JBrowse link
G H2AC13 H2A clustered histone 13 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:27,808,173...27,808,667
Ensembl chr 6:27,808,199...27,808,701
JBrowse link
G H2AC14 H2A clustered histone 14 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:27,814,302...27,814,777
Ensembl chr 6:27,814,302...27,814,777
JBrowse link
G H2AC15 H2A clustered histone 15 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:27,837,880...27,838,375
Ensembl chr 6:27,837,880...27,838,375
JBrowse link
G H2AC16 H2A clustered histone 16 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:27,865,317...27,865,798
Ensembl chr 6:27,865,317...27,865,798
JBrowse link
G H2AC17 H2A clustered histone 17 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:27,892,699...27,893,185
Ensembl chr 6:27,892,699...27,893,185
JBrowse link
G H2AC18 H2A clustered histone 18 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:149,842,218...149,842,750
Ensembl chr 1:149,842,188...149,842,736
JBrowse link
G H2AC19 H2A clustered histone 19 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:149,851,061...149,851,594
Ensembl chr 1:149,851,061...149,851,624
JBrowse link
G H2AC20 H2A clustered histone 20 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:149,886,918...149,887,411
Ensembl chr 1:149,886,918...149,887,411
JBrowse link
G H2AC21 H2A clustered histone 21 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:149,887,469...149,887,965
Ensembl chr 1:149,887,469...149,887,965
JBrowse link
G H2AC4 H2A clustered histone 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:26,033,092...26,033,618
Ensembl chr 6:26,033,092...26,033,618
JBrowse link
G H2AC6 H2A clustered histone 6 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:26,124,172...26,124,690
Ensembl chr 6:26,124,145...26,139,116
JBrowse link
G H2AC7 H2A clustered histone 7 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:26,198,784...26,199,293
Ensembl chr 6:26,198,784...26,199,293
JBrowse link
G H2AC8 H2A clustered histone 8 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:26,216,921...26,217,483
Ensembl chr 6:26,216,975...26,217,483
JBrowse link
G H2AJ H2A.J histone involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:14,774,405...14,778,002
Ensembl chr12:14,774,383...14,778,002
JBrowse link
G H2AL3 H2A.L variant histone 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:37,994,252...37,994,918
Ensembl chr  X:37,994,252...37,994,918
JBrowse link
G H2AP H2A.P histone involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:37,990,779...37,991,314
Ensembl chr  X:37,990,779...37,991,314
JBrowse link
G H2AW H2A.W histone involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:228,457,364...228,457,873
Ensembl chr 1:228,456,979...228,457,873
JBrowse link
G H2AX H2A.X variant histone involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,854...119,095,467
JBrowse link
G H2AZ1 H2A.Z variant histone 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:99,948,088...99,950,275
Ensembl chr 4:99,948,086...99,950,355
JBrowse link
G H2AZ2 H2A.Z variant histone 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:44,826,889...44,848,126
Ensembl chr 7:44,826,791...44,848,087
JBrowse link
G HDAC5 histone deacetylase 5 involved_in TAS (PMID:10869435) PINC PMID:10869435 NCBI chr17:44,076,753...44,123,651
Ensembl chr17:44,076,746...44,123,702
JBrowse link
G HELLS helicase, lymphoid specific acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3510059|PMID:15448183) MGI
Ensembl
PMID:15448183 GO_REF:0000107 MGI:3510059 NCBI chr10:94,545,778...94,613,905
Ensembl chr10:94,501,434...94,613,905
JBrowse link
G HMGA2 high mobility group AT-hook 2 involved_in IDA (PMID:16901784) UniProt PMID:16901784 NCBI chr12:65,824,460...65,966,291
Ensembl chr12:65,824,460...65,966,291
JBrowse link
G HOTAIR HOX transcript antisense RNA acts_upstream_of_or_within ISO (MGI:5528742|PMID:24075995) MGI PMID:24075995 MGI:5528742 NCBI chr12:53,962,308...53,974,956
Ensembl chr12:53,962,308...53,974,956
JBrowse link
G KDM1A lysine demethylase 1A involved_in ISO (MGI:4461095|PMID:20123967) BHF-UCL PMID:20123967 MGI:4461095 NCBI chr 1:23,019,443...23,083,691
Ensembl chr 1:23,019,443...23,083,689
JBrowse link
G KMT2D lysine methyltransferase 2D involved_in ISS UniProt GO_REF:0000024 NCBI chr12:49,018,975...49,060,884
Ensembl chr12:49,018,978...49,060,794
JBrowse link
G MACROH2A1 macroH2A.1 histone involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:135,334,381...135,401,998
Ensembl chr 5:135,333,900...135,399,914
JBrowse link
G MACROH2A2 macroH2A.2 histone involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:70,052,846...70,112,282
Ensembl chr10:70,052,544...70,112,282
JBrowse link
G MECP2 methyl-CpG binding protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3530434|PMID:15608638) MGI
Ensembl
PMID:15608638 GO_REF:0000107 MGI:3530434 NCBI chr  X:154,021,573...154,097,717
Ensembl chr  X:154,021,573...154,137,103
JBrowse link
G MORF4L1 mortality factor 4 like 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:78,872,890...78,898,139
Ensembl chr15:78,810,487...78,898,139
JBrowse link
G MORF4L2 mortality factor 4 like 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:103,675,498...103,688,047
Ensembl chr  X:103,675,496...103,688,158
JBrowse link
G MSL3 MSL complex subunit 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:11,758,159...11,775,772
Ensembl chr  X:11,758,159...11,775,772
JBrowse link
G MSL3P1 MSL complex subunit 3 pseudogene 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:233,865,437...233,868,409
Ensembl chr 2:233,865,437...233,868,444
JBrowse link
G PCGF1 polycomb group ring finger 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:74,505,043...74,507,695
Ensembl chr 2:74,505,043...74,507,695
JBrowse link
G PCGF2 polycomb group ring finger 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:38,733,898...38,749,817
Ensembl chr17:38,733,898...38,749,817
JBrowse link
G POLE3 DNA polymerase epsilon 3, accessory subunit involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:113,407,235...113,410,749
Ensembl chr 9:113,407,235...113,410,675
JBrowse link
G PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D involved_in ISS UniProt GO_REF:0000024 NCBI chr17:60,600,187...60,666,280
Ensembl chr17:60,600,183...60,666,280
JBrowse link
G SIRT1 sirtuin 1 involved_in IDA (PMID:15469825) BHF-UCL PMID:15469825 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G SIRT2 sirtuin 2 involved_in NAS (PMID:12697818) UniProt PMID:12697818 NCBI chr19:38,878,555...38,899,733
Ensembl chr19:38,878,555...38,899,862
JBrowse link
G TNP1 transition protein 1 involved_in IEP (PMID:11315969) UniProt PMID:11315969 NCBI chr 2:216,859,458...216,860,064
Ensembl chr 2:216,859,458...216,860,064
JBrowse link
G UBR2 ubiquitin protein ligase E3 component n-recognin 2 involved_in IBA
ISS
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000024 NCBI chr 6:42,563,954...42,693,505
Ensembl chr 6:42,564,029...42,693,505
JBrowse link
G UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked acts_upstream_of_or_within ISO (MGI:5305502|PMID:22192413) MGI PMID:22192413 MGI:5305502 NCBI chr  Y:13,231,827...13,480,670
Ensembl chr  Y:13,234,577...13,480,673
JBrowse link
DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3A DNA methyltransferase 3 alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3611125|PMID:16322236)
(MGI:3768461|PMID:17938196)
Ensembl
MGI
PMID:16322236 PMID:17938196 GO_REF:0000107 MGI:3611125 MGI:3768461 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
JBrowse link
G DNMT3B DNA methyltransferase 3 beta acts_upstream_of_or_within ISO (MGI:3768461|PMID:17938196) MGI PMID:17938196 MGI:3768461 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,356
JBrowse link
G HDAC1 histone deacetylase 1 involved_in IGI (PMID:23770133) BHF-UCL PMID:23770133 NCBI chr 1:32,292,083...32,333,628
Ensembl chr 1:32,292,083...32,333,635
JBrowse link
G HELLS helicase, lymphoid specific involved_in IBA
ISS
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000024 NCBI chr10:94,545,778...94,613,905
Ensembl chr10:94,501,434...94,613,905
JBrowse link
G KMT2B lysine methyltransferase 2B acts_upstream_of_or_within ISO (MGI:4849597|PMID:20808952) MGI PMID:20808952 MGI:4849597 NCBI chr19:35,717,818...35,738,878
Ensembl chr19:35,717,973...35,738,878
JBrowse link
G MBD2 methyl-CpG binding domain protein 2 involved_in IGI (PMID:23770133) BHF-UCL PMID:23770133 NCBI chr18:54,151,606...54,224,669
Ensembl chr18:54,151,606...54,224,669
JBrowse link
G MBD3 methyl-CpG binding domain protein 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3611125|PMID:16322236) Ensembl
MGI
PMID:16322236 GO_REF:0000107 MGI:3611125 NCBI chr19:1,573,596...1,592,865
Ensembl chr19:1,573,596...1,592,865
JBrowse link
G SIRT1 sirtuin 1 involved_in TAS (PMID:21947282) UniProt PMID:21947282 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 acts_upstream_of_or_within ISO (MGI:3611125|PMID:16322236) MGI PMID:16322236 MGI:3611125 NCBI chr19:10,960,999...11,062,277
Ensembl chr19:10,960,932...11,079,426
JBrowse link
gene silencing by RNA-directed DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 acts_upstream_of_or_within ISO (MGI:4830046|PMID:20573698)
(MGI:3054495|PMID:15340049)
MGI PMID:15340049 PMID:20573698 MGI:3054495 MGI:4830046 NCBI chr11:2,608,328...2,699,998
Ensembl chr11:2,608,328...2,699,994
JBrowse link
heterochromatin assembly by small RNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAM172A family with sequence similarity 172 member A involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:93,615,130...94,111,699
Ensembl chr 5:93,617,725...94,111,699
JBrowse link
G FAM172BP family with sequence similarity 172 member B, pseudogene involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:101,518,867...101,523,887
Ensembl chr 3:101,521,891...101,522,979
JBrowse link
G NRDE2 NRDE-2, necessary for RNA interference, domain containing involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:90,267,860...90,331,969
Ensembl chr14:90,267,860...90,331,969
JBrowse link
G ZNFX1 zinc finger NFX1-type containing 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:49,245,900...49,278,057
Ensembl chr20:49,237,946...49,278,426
JBrowse link
inactivation of X chromosome by heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr18:2,655,726...2,805,017
Ensembl chr18:2,655,726...2,805,017
JBrowse link
negative regulation of DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AICDA activation induced cytidine deaminase involved_in IDA (PMID:21496894) UniProt PMID:21496894 NCBI chr12:8,602,170...8,612,970
Ensembl chr12:8,602,170...8,612,867
JBrowse link
G APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr12:7,649,400...7,670,599
Ensembl chr12:7,649,400...7,665,908
JBrowse link
G TET1 tet methylcytosine dioxygenase 1 involved_in IMP (PMID:21496894) UniProt PMID:21496894 NCBI chr10:68,560,337...68,700,794
Ensembl chr10:68,560,337...68,694,487
JBrowse link
negative regulation of ribosomal DNA heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PHF2 PHD finger protein 2 involved_in IMP (PMID:20129925) UniProt PMID:20129925 NCBI chr 9:93,576,584...93,679,587
Ensembl chr 9:93,576,584...93,679,587
JBrowse link
G PHF8 PHD finger protein 8 involved_in IDA (PMID:20208542) UniProt PMID:20208542 NCBI chr  X:53,936,680...54,048,935
Ensembl chr  X:53,936,676...54,048,958
JBrowse link
positive regulation of DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF7IP activating transcription factor 7 interacting protein involved_in IMP (PMID:27732843) UniProt PMID:27732843 NCBI chr12:14,365,640...14,502,935
Ensembl chr12:14,365,676...14,502,931
JBrowse link
G DNMT1 DNA methyltransferase 1 involved_in IMP (PMID:24623306) UniProt PMID:24623306 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
JBrowse link
G MORC2 MORC family CW-type zinc finger 2 involved_in IDA (PMID:28581500), (PMID:29211708) UniProt PMID:28581500 PMID:29211708 NCBI chr22:30,925,130...30,968,774
Ensembl chr22:30,925,130...30,968,774
JBrowse link
G MPHOSPH8 M-phase phosphoprotein 8 involved_in IDA (PMID:28581500), (PMID:29211708) UniProt PMID:28581500 PMID:29211708 NCBI chr13:19,633,648...19,673,441
Ensembl chr13:19,633,659...19,673,441
JBrowse link
G PPHLN1 periphilin 1 involved_in IDA (PMID:28581500) UniProt PMID:28581500 NCBI chr12:42,326,126...42,448,621
Ensembl chr12:42,238,447...42,459,715
JBrowse link
G RESF1 retroelement silencing factor 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr12:31,959,415...31,993,107
Ensembl chr12:31,959,370...31,993,107
JBrowse link
G SETDB1 SET domain bifurcated histone lysine methyltransferase 1 involved_in IBA
ISS
IMP
(PMID:21873635)
(PMID:24623306), (PMID:27732843)
GO_Central
UniProt
PMID:21873635 PMID:24623306 PMID:27732843 GO_REF:0000024 NCBI chr 1:150,926,263...150,964,737
Ensembl chr 1:150,926,263...150,964,744
JBrowse link
G SETDB2 SET domain bifurcated histone lysine methyltransferase 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:49,444,274...49,495,003
Ensembl chr13:49,444,374...49,495,003
JBrowse link
G TASOR transcription activation suppressor involved_in IDA
IBA
(PMID:28581500), (PMID:29211708)
(PMID:21873635)
UniProt
GO_Central
PMID:21873635 PMID:28581500 PMID:29211708 NCBI chr 3:56,620,132...56,683,265
Ensembl chr 3:56,620,132...56,683,265
JBrowse link
G TRIM28 tripartite motif containing 28 involved_in IMP
ISS
(PMID:24623306) UniProt PMID:24623306 GO_REF:0000024 NCBI chr19:58,544,064...58,550,722
Ensembl chr19:58,544,064...58,550,722
JBrowse link
G ZNF304 zinc finger protein 304 involved_in IMP (PMID:24623306) UniProt PMID:24623306 NCBI chr19:57,351,253...57,359,898
Ensembl chr19:57,351,271...57,359,898
JBrowse link
positive regulation of heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TPR translocated promoter region, nuclear basket protein involved_in IMP (PMID:20407419) UniProt PMID:20407419 NCBI chr 1:186,311,652...186,375,253
Ensembl chr 1:186,311,652...186,375,693
JBrowse link
rDNA heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAZ2A bromodomain adjacent to zinc finger domain 2A involved_in
acts_upstream_of_or_within
ISS
ISO
(MGI:4462332|PMID:20168299)
(MGI:3653583|PMID:16678107)
UniProt
MGI
PMID:16678107 PMID:20168299 GO_REF:0000024 MGI:3653583 MGI:4462332 NCBI chr12:56,595,596...56,636,816
Ensembl chr12:56,595,596...56,636,816
JBrowse link
G BEND3 BEN domain containing 3 involved_in IMP
IBA
(PMID:26100909)
(PMID:21873635)
UniProt
GO_Central
PMID:21873635 PMID:26100909 NCBI chr 6:107,065,182...107,115,515
Ensembl chr 6:107,065,182...107,115,515
JBrowse link
G RRP8 ribosomal RNA processing 8 involved_in IBA
IDA
(PMID:21873635)
(PMID:18485871)
GO_Central
UniProt
PMID:18485871 PMID:21873635 NCBI chr11:6,514,830...6,603,678
Ensembl chr11:6,595,072...6,603,616
JBrowse link
G SIRT1 sirtuin 1 involved_in TAS
IDA
(PMID:18485871) Reactome
UniProt
PMID:18485871 Reactome:R-HSA-427359 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G SIRT2 sirtuin 2 involved_in NAS (PMID:11427894) UniProt PMID:11427894 NCBI chr19:38,878,555...38,899,733
Ensembl chr19:38,878,555...38,899,862
JBrowse link
G SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:143,513,501...143,557,486
Ensembl chr 4:143,513,702...143,557,486
JBrowse link
G SUV39H1 SUV39H1 histone lysine methyltransferase involved_in IDA
TAS
(PMID:18485871) UniProt
Reactome
PMID:18485871 Reactome:R-HSA-427359 NCBI chr  X:48,695,554...48,709,016
Ensembl chr  X:48,695,554...48,709,016
JBrowse link
G UBTF upstream binding transcription factor acts_upstream_of_or_within ISO (MGI:3836497|PMID:19103806) MGI PMID:19103806 MGI:3836497 NCBI chr17:44,205,036...44,221,304
Ensembl chr17:44,205,033...44,221,626
JBrowse link
regulation of DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU5F1 POU class 5 homeobox 1 involved_in IDA (PMID:19736317) BHF-UCL PMID:19736317 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731
JBrowse link
regulation of ribosomal DNA heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MACROH2A1 macroH2A.1 histone NOT|involved_in IMP (PMID:24071584) UniProt PMID:24071584 NCBI chr 5:135,334,381...135,401,998
Ensembl chr 5:135,333,900...135,399,914
JBrowse link
subtelomeric heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DOT1L DOT1 like histone lysine methyltransferase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:2,163,933...2,232,578
Ensembl chr19:2,163,933...2,232,578
JBrowse link
G DPY30 dpy-30 histone methyltransferase complex regulatory subunit involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:32,011,649...32,039,840
Ensembl chr 2:31,867,809...32,039,805
JBrowse link
G DYDC1 DPY30 domain containing 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:80,336,013...80,356,787
Ensembl chr10:80,336,105...80,356,755
JBrowse link
G DYDC2 DPY30 domain containing 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:80,344,745...80,368,073
Ensembl chr10:80,344,745...80,368,073
JBrowse link
G EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit involved_in ISS (PMID:9214638) ARUK-UCL PMID:9214638 NCBI chr17:42,700,275...42,745,078
Ensembl chr17:42,700,275...42,745,049
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in IGI (PMID:9214638) ARUK-UCL PMID:9214638 NCBI chr 7:148,807,374...148,884,344
Ensembl chr 7:148,807,257...148,884,321
JBrowse link
G H3-3A H3.3 histone A acts_upstream_of_or_within ISO (MGI:5694896|PMID:26159997) MGI PMID:26159997 MGI:5694896 NCBI chr 1:226,061,831...226,072,019
Ensembl chr 1:226,061,851...226,072,019
JBrowse link
G H3-3B H3.3 histone B acts_upstream_of_or_within ISO (MGI:5694896|PMID:26159997) MGI PMID:26159997 MGI:5694896 NCBI chr17:75,776,434...75,779,779
Ensembl chr17:75,776,434...75,785,893
JBrowse link
G H3-5 H3.5 histone involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:31,791,185...31,792,298
Ensembl chr12:31,791,185...31,792,298
JBrowse link
G HAT1 histone acetyltransferase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 2:171,922,425...171,983,686
Ensembl chr 2:171,922,448...171,983,686
JBrowse link
G RIF1 replication timing regulatory factor 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 2:151,409,902...151,534,200
Ensembl chr 2:151,409,883...151,508,013
JBrowse link
G SIRT2 sirtuin 2 involved_in NAS (PMID:11427894) UniProt PMID:11427894 NCBI chr19:38,878,555...38,899,733
Ensembl chr19:38,878,555...38,899,862
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18539
    metabolic process 11870
      negative regulation of metabolic process 3368
        negative regulation of macromolecule metabolic process 3122
          negative regulation of gene expression 1206
            negative regulation of gene expression, epigenetic 108
              heterochromatin assembly 102
                DNA methylation-dependent heterochromatin assembly + 25
                heterochromatin assembly by small RNA + 4
                heterochromatin boundary formation 0
                heterochromatin domain assembly + 0
                heterochromatin island assembly + 0
                inactivation of X chromosome by heterochromatin assembly 1
                negative regulation of heterochromatin assembly + 5
                positive regulation of heterochromatin assembly + 12
                pre-transcriptional gene silencing by RNA + 1
                rDNA heterochromatin assembly + 11
                regulation of heterochromatin assembly + 19
                silent mating-type cassette heterochromatin assembly + 0
                subtelomeric heterochromatin assembly 12
Path 2
Term Annotations click to browse term
  biological_process 18539
    cellular process 17460
      cellular component organization or biogenesis 6721
        cellular component organization 6526
          organelle organization 3985
            chromosome organization 1016
              chromatin organization 549
                regulation of gene expression, epigenetic 175
                  negative regulation of gene expression, epigenetic 108
                    heterochromatin assembly 102
                      DNA methylation-dependent heterochromatin assembly + 25
                      heterochromatin assembly by small RNA + 4
                      heterochromatin boundary formation 0
                      heterochromatin domain assembly + 0
                      heterochromatin island assembly + 0
                      inactivation of X chromosome by heterochromatin assembly 1
                      negative regulation of heterochromatin assembly + 5
                      positive regulation of heterochromatin assembly + 12
                      pre-transcriptional gene silencing by RNA + 1
                      rDNA heterochromatin assembly + 11
                      regulation of heterochromatin assembly + 19
                      silent mating-type cassette heterochromatin assembly + 0
                      subtelomeric heterochromatin assembly 12
paths to the root