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ONTOLOGY REPORT - ANNOTATIONS

Term:Cul4A-RING E3 ubiquitin ligase complex
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Accession:GO:0031464 term browser browse the term
Definition:A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.
Synonyms:exact_synonym: CDL4 complex;   CRL4 complex;   DCX complex;   cullin-RING ligase 4A
 narrow_synonym: VDC complex
 related_synonym: SCF4 complex


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Cul4A-RING E3 ubiquitin ligase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 located_in ISO (PMID:24076655) RGD PMID:24076655 NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B part_of ISO (PMID:21628527) RGD PMID:21628527 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cop1 COP1, E3 ubiquitin ligase part_of ISO (PMID:14739464) RGD PMID:14739464 NCBI chr13:71,467,164...71,561,826
Ensembl chr13:71,429,961...71,538,890 		JBrowse link
G Crbn cereblon part_of ISS
ISO
IBA		 GO_REF:0000024
(PMID:20223979)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:20223979 GO_REF:0000024 GO_REF:0000033 NCBI chr 4:139,701,154...139,719,949
Ensembl chr 4:139,701,094...139,719,938 		JBrowse link
G Cul4a cullin 4A part_of
located_in		 ISO
IBA		 (PMID:12732143), (PMID:14739464), (PMID:17085480), (PMID:18794347), (PMID:20129063), (PMID:20223979)
(PMID:22118460)
GO_REF:0000033
(MGI:6867266|PMID:22118460)		 RGD
GO_Central		 PMID:12732143 PMID:14739464 PMID:17085480 PMID:18794347 PMID:20129063 More... GO_REF:0000033 MGI:6867266 NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330 		JBrowse link
G Cul4b cullin 4B located_in
part_of		 ISO (PMID:22118460)
(MGI:6867266|PMID:22118460)		 RGD PMID:22118460 MGI:6867266 NCBI chr  X:117,287,481...117,326,688
Ensembl chr  X:117,287,484...117,326,688 		JBrowse link
G Ddb1 damage-specific DNA binding protein 1 part_of
located_in		 ISS
ISO
IEA		 GO_REF:0000024
(PMID:12732143), (PMID:14739464), (PMID:18794347), (PMID:20129063), (PMID:20223979)
GO_REF:0000107
(PMID:22118460)
(MGI:6867266|PMID:22118460)		 UniProt
RGD
Ensembl		 PMID:12732143 PMID:14739464 PMID:18794347 PMID:20129063 PMID:20223979 More... GO_REF:0000024 GO_REF:0000107 MGI:6867266 NCBI chr 1:207,252,890...207,278,685
Ensembl chr 1:207,252,890...207,278,676 		JBrowse link
G Ddb2 damage specific DNA binding protein 2 located_in
part_of		 ISO (PMID:22118460)
(MGI:6867266|PMID:22118460)		 RGD PMID:22118460 MGI:6867266 NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631 		JBrowse link
G Det1 DET1 partner of COP1 E3 ubiquitin ligase part_of ISO (PMID:14739464) RGD PMID:14739464 NCBI chr 1:132,749,736...132,765,963
Ensembl chr 1:132,749,756...132,765,923 		JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog part_of ISO (PMID:17085480), (PMID:18794347), (PMID:20129063), (PMID:21628527) RGD PMID:17085480 PMID:18794347 PMID:20129063 PMID:21628527 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890 		JBrowse link
G Ercc8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit part_of ISO
IBA		 (PMID:12732143)
GO_REF:0000033		 RGD
GO_Central		 PMID:12732143 GO_REF:0000033 NCBI chr 2:39,647,393...39,686,229
Ensembl chr 2:39,647,452...39,684,859 		JBrowse link
G Glmn glomulin, FKBP associated protein part_of ISO UniProtKB:Q13619 (PMID:22405651) RGD PMID:22405651 NCBI chr14:2,187,144...2,231,295
Ensembl chr14:2,187,642...2,230,420 		JBrowse link
G Rbx1 ring-box 1 part_of
located_in		 ISO (PMID:12732143), (PMID:14739464), (PMID:17085480), (PMID:18794347), (PMID:20129063), (PMID:20223979)
(PMID:22118460)
(MGI:6867266|PMID:22118460)		 RGD PMID:12732143 PMID:14739464 PMID:17085480 PMID:18794347 PMID:20129063 More... MGI:6867266 NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051 		JBrowse link
G Trpc4ap transient receptor potential cation channel, subfamily C, member 4 associated protein part_of ISO
IBA		 (PMID:20551172)
GO_REF:0000033		 RGD
GO_Central		 PMID:20551172 GO_REF:0000033 NCBI chr 3:144,122,003...144,192,986
Ensembl chr 3:144,122,003...144,192,986 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21392
    protein-containing complex 6987
      intracellular protein-containing complex 987
        ubiquitin ligase complex 347
          cullin-RING ubiquitin ligase complex 196
            Cul4-RING E3 ubiquitin ligase complex 36
              Cul4A-RING E3 ubiquitin ligase complex 14
Path 2
Term Annotations click to browse term
  cellular_component 21392
    protein-containing complex 6987
      catalytic complex 1938
        transferase complex 905
          ubiquitin ligase complex 347
            cullin-RING ubiquitin ligase complex 196
              Cul4-RING E3 ubiquitin ligase complex 36
                Cul4A-RING E3 ubiquitin ligase complex 14
paths to the root