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ONTOLOGY REPORT - ANNOTATIONS


Term:Cul4A-RING E3 ubiquitin ligase complex
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Accession:GO:0031464 term browser browse the term
Definition:A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.
Synonyms:exact_synonym: CDL4 complex;   CRL4 complex;   DCX complex;   cullin-RING ligase 4A
 narrow_synonym: VDC complex
 related_synonym: SCF4 complex



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Cul4A-RING E3 ubiquitin ligase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 part_of
located_in
IEA
ISO
(PMID:24076655) Ensembl
UniProt
PMID:24076655 GO_REF:0000107 NCBI chr 7:60,707,483...60,824,117
Ensembl chr 7:60,710,051...60,824,101
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B part_of IEA Ensembl GO_REF:0000107 NCBI chr 5:59,731,224...59,735,831
Ensembl chr 5:59,731,206...59,735,831
JBrowse link
G COP1 COP1 E3 ubiquitin ligase part_of IEA Ensembl GO_REF:0000107 NCBI chr 9:117,913,504...118,114,268
Ensembl chr 9:117,915,443...118,114,259
JBrowse link
G CRBN cereblon part_of IEA
IBA
Ensembl
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr13:59,733,503...59,757,776
Ensembl chr13:59,730,639...59,757,860
JBrowse link
G CUL4A cullin 4A part_of
located_in
IEA
ISO
IBA
(PMID:22118460)
(MGI:6867266|PMID:22118460)
Ensembl
ComplexPortal
GO_Central
TreeGrafter
PMID:22118460 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:6867266 NCBI chr11:78,557,030...78,588,964
Ensembl chr11:78,557,013...78,589,193
JBrowse link
G CUL4B cullin 4B located_in ISO (PMID:22118460)
(MGI:6867266|PMID:22118460)
ComplexPortal PMID:22118460 MGI:6867266 NCBI chr  X:98,668,945...98,730,582
Ensembl chr  X:98,668,953...98,730,565
JBrowse link
G DDB1 damage specific DNA binding protein 1 part_of
located_in
IEA
ISO
(PMID:22118460)
(MGI:6867266|PMID:22118460)
Ensembl
ComplexPortal
PMID:22118460 GO_REF:0000107 MGI:6867266 NCBI chr 2:10,171,554...10,201,602
Ensembl chr 2:10,171,502...10,201,598
JBrowse link
G DDB2 damage specific DNA binding protein 2 located_in ISO (PMID:22118460)
(MGI:6867266|PMID:22118460)
ComplexPortal PMID:22118460 MGI:6867266 NCBI chr 2:15,342,614...15,370,623
Ensembl chr 2:15,337,743...15,383,120
JBrowse link
G DET1 DET1 partner of COP1 E3 ubiquitin ligase part_of IEA Ensembl GO_REF:0000107 NCBI chr 1:191,263,449...191,284,973
Ensembl chr 1:191,263,448...191,284,967
JBrowse link
G DTL denticleless E3 ubiquitin protein ligase homolog part_of IEA Ensembl GO_REF:0000107 NCBI chr 9:131,225,840...131,275,426
Ensembl chr 9:131,227,705...131,275,451
JBrowse link
G ERCC8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit part_of IEA
IBA
Ensembl
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr16:39,704,602...39,770,330
Ensembl chr16:39,701,702...39,770,315
JBrowse link
G GLMN glomulin, FKBP associated protein part_of IEA Ensembl GO_REF:0000107 NCBI chr 4:124,773,957...124,813,336
Ensembl chr 4:124,773,980...124,813,335
JBrowse link
G RBX1 ring-box 1 located_in
part_of
ISO
IEA
(PMID:22118460)
(MGI:6867266|PMID:22118460)
ComplexPortal
Ensembl
PMID:22118460 GO_REF:0000107 MGI:6867266 NCBI chr 5:7,500,492...7,515,388
Ensembl chr 5:7,500,490...7,515,370
JBrowse link
G TRPC4AP transient receptor potential cation channel subfamily C member 4 associated protein part_of IEA
IBA
InterPro
Ensembl
TreeGrafter
GO_Central
GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr17:38,385,650...38,468,290
Ensembl chr17:38,385,653...38,468,295
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18662
    protein-containing complex 5998
      intracellular protein-containing complex 906
        ubiquitin ligase complex 319
          cullin-RING ubiquitin ligase complex 187
            Cul4-RING E3 ubiquitin ligase complex 36
              Cul4A-RING E3 ubiquitin ligase complex 14
Path 2
Term Annotations click to browse term
  cellular_component 18662
    protein-containing complex 5998
      catalytic complex 1707
        transferase complex 836
          ubiquitin ligase complex 319
            cullin-RING ubiquitin ligase complex 187
              Cul4-RING E3 ubiquitin ligase complex 36
                Cul4A-RING E3 ubiquitin ligase complex 14
paths to the root