ONTOLOGY REPORT - ANNOTATIONS
Term: Cul4A-RING E3 ubiquitin ligase complex
Accession: GO:0031464
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Definition: A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.
Synonyms: exact_synonym: CDL4 complex; CRL4 complex; DCX complex; cullin-RING ligase 4A
narrow_synonym: VDC complex
related_synonym: SCF4 complex
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ARIH1
ariadne RBR E3 ubiquitin protein ligase 1
part_of located_in
IEA ISO
(PMID:24076655)
Ensembl UniProt
PMID:24076655
GO_REF:0000107
NCBI chr 7:60,707,483...60,824,117
Ensembl chr 7:60,710,051...60,824,101
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CDKN1B
cyclin dependent kinase inhibitor 1B
part_of
IEA
Ensembl
GO_REF:0000107
NCBI chr 5:59,731,224...59,735,831
Ensembl chr 5:59,731,206...59,735,831
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COP1
COP1 E3 ubiquitin ligase
part_of
IEA
Ensembl
GO_REF:0000107
NCBI chr 9:117,913,504...118,114,268
Ensembl chr 9:117,915,443...118,114,259
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CRBN
cereblon
part_of
IEA IBA
Ensembl TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr13:59,733,503...59,757,776
Ensembl chr13:59,730,639...59,757,860
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CUL4A
cullin 4A
part_of located_in
IEA ISO IBA
(PMID:22118460) (MGI:6867266|PMID:22118460)
Ensembl ComplexPortal GO_Central TreeGrafter
PMID:22118460
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:6867266
NCBI chr11:78,557,030...78,588,964
Ensembl chr11:78,557,013...78,589,193
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CUL4B
cullin 4B
located_in
ISO
(PMID:22118460) (MGI:6867266|PMID:22118460)
ComplexPortal
PMID:22118460
MGI:6867266
NCBI chr X:98,668,945...98,730,582
Ensembl chr X:98,668,953...98,730,565
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DDB1
damage specific DNA binding protein 1
part_of located_in
IEA ISO
(PMID:22118460) (MGI:6867266|PMID:22118460)
Ensembl ComplexPortal
PMID:22118460
GO_REF:0000107 MGI:6867266
NCBI chr 2:10,171,554...10,201,602
Ensembl chr 2:10,171,502...10,201,598
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DDB2
damage specific DNA binding protein 2
located_in
ISO
(PMID:22118460) (MGI:6867266|PMID:22118460)
ComplexPortal
PMID:22118460
MGI:6867266
NCBI chr 2:15,342,614...15,370,623
Ensembl chr 2:15,337,743...15,383,120
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DET1
DET1 partner of COP1 E3 ubiquitin ligase
part_of
IEA
Ensembl
GO_REF:0000107
NCBI chr 1:191,263,449...191,284,973
Ensembl chr 1:191,263,448...191,284,967
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DTL
denticleless E3 ubiquitin protein ligase homolog
part_of
IEA
Ensembl
GO_REF:0000107
NCBI chr 9:131,225,840...131,275,426
Ensembl chr 9:131,227,705...131,275,451
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ERCC8
ERCC excision repair 8, CSA ubiquitin ligase complex subunit
part_of
IEA IBA
Ensembl GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr16:39,704,602...39,770,330
Ensembl chr16:39,701,702...39,770,315
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GLMN
glomulin, FKBP associated protein
part_of
IEA
Ensembl
GO_REF:0000107
NCBI chr 4:124,773,957...124,813,336
Ensembl chr 4:124,773,980...124,813,335
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RBX1
ring-box 1
located_in part_of
ISO IEA
(PMID:22118460) (MGI:6867266|PMID:22118460)
ComplexPortal Ensembl
PMID:22118460
GO_REF:0000107 MGI:6867266
NCBI chr 5:7,500,492...7,515,388
Ensembl chr 5:7,500,490...7,515,370
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TRPC4AP
transient receptor potential cation channel subfamily C member 4 associated protein
part_of
IEA IBA
InterPro Ensembl TreeGrafter GO_Central
GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr17:38,385,650...38,468,290
Ensembl chr17:38,385,653...38,468,295
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