ONTOLOGY REPORT - ANNOTATIONS
Term: keratinization
Accession: GO:0031424
browse the term
Definition: The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns.
G
ABCA12
ATP binding cassette subfamily A member 12
acts_upstream_of_or_within involved_in
ISO IEA
(MGI:3807143|PMID:18632686) (MGI:3829841|PMID:18957418) (MGI:4460077|PMID:18802465)
MGI Ensembl
PMID:18632686 PMID:18802465 PMID:18957418
GO_REF:0000107 MGI:3807143 MGI:3829841 MGI:4460077
NCBI chr 2:214,931,542...215,138,626
Ensembl chr 2:214,931,542...215,138,626
G
CASP14
caspase 14
involved_in
TAS
(PMID:18309324)
UniProt
PMID:18309324
NCBI chr19:15,049,480...15,058,293
Ensembl chr19:15,049,480...15,058,293
G
CDH3
cadherin 3
involved_in
IMP
(PMID:22696062)
UniProt
PMID:22696062
NCBI chr16:68,645,310...68,733,771
Ensembl chr16:68,636,189...68,727,468
G
CNFN
cornifelin
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr19:42,387,019...42,390,297
Ensembl chr19:42,387,019...42,390,297
G
EVPL
envoplakin
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr17:76,006,845...76,027,306
Ensembl chr17:76,004,502...76,027,306
G
HRNR
hornerin
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,212,076...152,224,193
Ensembl chr 1:152,212,076...152,224,193
G
IL1A
interleukin 1 alpha
involved_in
ISO IEA
RGD Ensembl
PMID:20385541
GO_REF:0000107 RGD:4142790
NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
G
IVL
involucrin
involved_in
IEA
InterPro UniProt
GO_REF:0000002 GO_REF:0000043
NCBI chr 1:152,908,546...152,911,886
Ensembl chr 1:152,908,546...152,911,886
G
KAZN
kazrin, periplakin interacting protein
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:13,892,824...15,118,043
Ensembl chr 1:13,892,792...15,118,043
G
KRT1
keratin 1
involved_in
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,674,736...52,680,407
Ensembl chr12:52,674,736...52,680,407
G
KRT16
keratin 16
involved_in
ISS IEA
UniProt Ensembl
GO_REF:0000024 GO_REF:0000107
NCBI chr17:41,609,778...41,612,767
Ensembl chr17:41,609,778...41,615,899
G
KRT17
keratin 17
acts_upstream_of_or_within involved_in
ISO IEA
(MGI:3525934|PMID:15601842)
MGI Ensembl
PMID:15601842
GO_REF:0000107 MGI:3525934
NCBI chr17:41,619,442...41,624,575
Ensembl chr17:41,619,442...41,624,842
G
KRT2
keratin 2
involved_in
IDA IEA IBA
(PMID:12598329)
UniProt TreeGrafter GO_Central
PMID:12598329
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,644,558...52,652,211
Ensembl chr12:52,644,558...52,652,211
G
KRT3
keratin 3
involved_in
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,789,685...52,796,117
Ensembl chr12:52,789,685...52,796,117
G
KRT4
keratin 4
involved_in
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,806,549...52,814,116
Ensembl chr12:52,806,549...52,814,116
G
KRT5
keratin 5
involved_in
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,514,575...52,520,394
Ensembl chr12:52,514,575...52,520,530
G
KRT6A
keratin 6A
acts_upstream_of_or_within involved_in
ISO IBA IEA
(MGI:3525934|PMID:15601842)
MGI GO_Central TreeGrafter
PMID:15601842
GO_REF:0000033 GO_REF:0000118 MGI:3525934
NCBI chr12:52,487,176...52,493,257
Ensembl chr12:52,487,176...52,493,257
G
KRT6B
keratin 6B
acts_upstream_of_or_within involved_in
ISO IEA IBA
(MGI:3525934|PMID:15601842)
MGI TreeGrafter GO_Central
PMID:15601842
GO_REF:0000033 GO_REF:0000118 MGI:3525934
NCBI chr12:52,446,651...52,452,146
Ensembl chr12:52,446,651...52,452,146
G
KRT6C
keratin 6C
involved_in
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,468,516...52,473,805
Ensembl chr12:52,468,516...52,473,805
G
KRT7
keratin 7
involved_in
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,233,243...52,255,853
Ensembl chr12:52,232,520...52,252,186
G
KRT71
keratin 71
involved_in
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,543,909...52,553,145
Ensembl chr12:52,543,909...52,553,145
G
KRT72
keratin 72
involved_in
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,585,589...52,602,953
Ensembl chr12:52,585,589...52,601,538
G
KRT73
keratin 73
involved_in
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,607,570...52,630,761
Ensembl chr12:52,607,570...52,618,559
G
KRT74
keratin 74
involved_in
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,565,782...52,573,843
Ensembl chr12:52,565,782...52,573,843
G
KRT75
keratin 75
involved_in
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,424,070...52,434,371
Ensembl chr12:52,424,070...52,434,371
G
KRT76
keratin 76
involved_in
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,768,155...52,777,345
Ensembl chr12:52,768,155...52,777,345
G
KRT77
keratin 77
involved_in
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,689,626...52,703,524
Ensembl chr12:52,689,626...52,703,524
G
KRT78
keratin 78
involved_in
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,837,804...52,848,994
Ensembl chr12:52,837,804...52,849,092
G
KRT79
keratin 79
involved_in
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,821,408...52,834,311
Ensembl chr12:52,821,408...52,834,311
G
KRT8
keratin 8
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chr12:52,897,191...52,949,860
Ensembl chr12:52,897,187...52,949,954
G
KRT80
keratin 80
involved_in
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,168,996...52,192,014
Ensembl chr12:52,168,996...52,192,014
G
KRT81
keratin 81
involved_in
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,285,913...52,308,624
Ensembl chr12:52,285,913...52,291,534
G
KRT82
keratin 82
involved_in
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,393,931...52,406,335
Ensembl chr12:52,393,931...52,406,335
G
KRT83
keratin 83
involved_in
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,314,301...52,321,398
Ensembl chr12:52,314,301...52,321,398
G
KRT84
keratin 84
involved_in
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,377,812...52,386,977
Ensembl chr12:52,377,812...52,385,652
G
KRT85
keratin 85
involved_in
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,360,006...52,367,481
Ensembl chr12:52,360,006...52,367,481
G
KRT86
keratin 86
involved_in
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr12:52,274,645...52,309,163
Ensembl chr12:52,249,300...52,309,163
G
KRT87P
keratin 87, pseudogene
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chr12:52,250,544...52,258,508
Ensembl chr12:52,250,466...52,258,553
G
KRTAP6-1
keratin associated protein 6-1
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr21:30,613,431...30,613,930
Ensembl chr21:30,613,431...30,613,930
G
KRTAP6-2
keratin associated protein 6-2
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr21:30,598,590...30,598,902
Ensembl chr21:30,598,590...30,598,902
G
KRTAP6-3
keratin associated protein 6-3
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr21:30,592,440...30,593,075
Ensembl chr21:30,592,440...30,593,075
G
LCE1A
late cornified envelope 1A
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,827,473...152,828,097
Ensembl chr 1:152,827,473...152,828,097
G
LCE1B
late cornified envelope 1B
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,811,971...152,813,108
Ensembl chr 1:152,811,971...152,813,108
G
LCE1C
late cornified envelope 1C
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,804,832...152,806,651
Ensembl chr 1:152,804,832...152,806,651
G
LCE1D
late cornified envelope 1D
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,796,721...152,798,181
Ensembl chr 1:152,796,721...152,798,181
G
LCE1E
late cornified envelope 1E
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,786,257...152,788,426
Ensembl chr 1:152,786,214...152,788,426
G
LCE1F
late cornified envelope 1F
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,775,140...152,777,024
Ensembl chr 1:152,775,140...152,777,024
G
LCE2A
late cornified envelope 2A
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,698,345...152,699,442
Ensembl chr 1:152,698,345...152,699,442
G
LCE2B
late cornified envelope 2B
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,686,123...152,687,397
Ensembl chr 1:152,686,123...152,687,397
G
LCE2C
late cornified envelope 2C
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,675,279...152,676,569
Ensembl chr 1:152,675,279...152,676,569
G
LCE2D
late cornified envelope 2D
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,663,380...152,664,659
Ensembl chr 1:152,663,380...152,664,659
G
LCE3A
late cornified envelope 3A
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,622,834...152,623,103
Ensembl chr 1:152,622,834...152,623,103
G
LCE3B
late cornified envelope 3B
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,613,811...152,614,098
Ensembl chr 1:152,613,811...152,614,098
G
LCE3C
late cornified envelope 3C
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,600,234...152,601,086
Ensembl chr 1:152,600,234...152,601,086
G
LCE3D
late cornified envelope 3D
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,579,381...152,580,516
Ensembl chr 1:152,579,381...152,580,516
G
LCE3E
late cornified envelope 3E
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,565,654...152,566,780
Ensembl chr 1:152,565,654...152,566,780
G
LCE4A
late cornified envelope 4A
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,708,160...152,709,434
Ensembl chr 1:152,708,160...152,709,434
G
LCE5A
late cornified envelope 5A
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,510,803...152,512,177
Ensembl chr 1:152,510,803...152,512,177
G
LCE6A
late cornified envelope 6A
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,842,856...152,843,983
Ensembl chr 1:152,842,856...152,843,983
G
LCE7A
late cornified envelope 7A
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,859,996...152,861,252
Ensembl chr 1:152,859,996...152,861,252 Ensembl chr 1:152,859,996...152,861,252
G
LORICRIN
loricrin cornified envelope precursor protein
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:153,259,687...153,262,124
Ensembl chr 1:153,259,687...153,262,124
G
PPHLN1
periphilin 1
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr12:42,326,167...42,448,621
Ensembl chr12:42,238,447...42,459,715
G
PPL
periplakin
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr16:4,882,507...4,937,148
Ensembl chr16:4,882,507...4,960,741
G
SFN
stratifin
acts_upstream_of_or_within involved_in
ISO IEA
(MGI:55181|PMID:6174530)
MGI Ensembl
PMID:6174530
GO_REF:0000107 MGI:55181
NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456
G
SHARPIN
SHANK associated RH domain interactor
acts_upstream_of_or_within involved_in
ISO IEA
(MGI:75289|PMID:7792947)
MGI Ensembl
PMID:7792947
GO_REF:0000107 MGI:75289
NCBI chr 8:144,098,637...144,103,773
Ensembl chr 8:144,098,633...144,108,124
G
SPRR1A
small proline rich protein 1A
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,984,081...152,985,814
Ensembl chr 1:152,984,081...152,985,814
G
SPRR1B
small proline rich protein 1B
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:153,031,203...153,032,900
Ensembl chr 1:153,031,203...153,032,900
G
SPRR2B
small proline rich protein 2B
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:153,070,226...153,087,799
Ensembl chr 1:153,070,226...153,071,611
G
SPRR2D
small proline rich protein 2D
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:153,039,732...153,041,120
Ensembl chr 1:153,039,732...153,041,931
G
SPRR2E
small proline rich protein 2E
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:153,093,135...153,094,526
Ensembl chr 1:153,093,135...153,106,184
G
SPRR2F
small proline rich protein 2F
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:153,112,121...153,119,468
Ensembl chr 1:153,112,121...153,113,516
G
SPRR2G
small proline rich protein 2G
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:153,149,582...153,203,278
Ensembl chr 1:153,149,582...153,150,890
G
SPRR3
small proline rich protein 3
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:153,001,749...153,003,856
Ensembl chr 1:153,001,747...153,003,856
G
SPRR4
small proline rich protein 4
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,968,750...152,972,574
Ensembl chr 1:152,970,648...152,972,574
G
TCHH
trichohyalin
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr 1:152,106,317...152,115,444
Ensembl chr 1:152,106,317...152,115,444
G
TGM1
transglutaminase 1
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr14:24,249,114...24,263,177
Ensembl chr14:24,249,114...24,264,432
G
TGM3
transglutaminase 3
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chr20:2,296,001...2,341,079
Ensembl chr20:2,296,001...2,341,079
G
TTBK2
tau tubulin kinase 2
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chr15:42,738,730...42,921,000
Ensembl chr15:42,738,730...42,920,809
G
CASP14
caspase 14
involved_in
TAS
(PMID:18309324)
UniProt
PMID:18309324
NCBI chr19:15,049,480...15,058,293
Ensembl chr19:15,049,480...15,058,293
G
CERS3
ceramide synthase 3
involved_in
ISS IEA
UniProt Ensembl
GO_REF:0000024 GO_REF:0000107
NCBI chr15:100,400,395...100,544,683
Ensembl chr15:100,400,395...100,544,995
G
CYP26B1
cytochrome P450 family 26 subfamily B member 1
acts_upstream_of_or_within involved_in
ISO IEA
(MGI:5466369|PMID:22366455)
MGI Ensembl
PMID:22366455
GO_REF:0000107 MGI:5466369
NCBI chr 2:72,129,238...72,147,862
Ensembl chr 2:72,129,238...72,147,862
G
KLK5
kallikrein related peptidase 5
involved_in
TAS
Reactome
Reactome:R-HSA-6809371
NCBI chr19:50,943,303...50,953,038
Ensembl chr19:50,943,303...50,953,093
G
LIPK
lipase family member K
involved_in
TAS
Reactome
Reactome:R-HSA-6809371
NCBI chr10:88,706,249...88,752,776
Ensembl chr10:88,706,249...88,752,776
G
LIPM
lipase family member M
involved_in
TAS
Reactome
Reactome:R-HSA-6809371
NCBI chr10:88,802,730...88,820,546
Ensembl chr10:88,802,730...88,820,546
G
LIPN
lipase family member N
involved_in
TAS
Reactome
Reactome:R-HSA-6809371
NCBI chr10:88,757,226...88,779,626
Ensembl chr10:88,759,982...88,779,626
G
TMEM79
transmembrane protein 79
acts_upstream_of_or_within involved_in
ISO IEA
(MGI:5519142|PMID:24084074)
MGI Ensembl
PMID:24084074
GO_REF:0000107 MGI:5519142
NCBI chr 1:156,282,932...156,292,443
Ensembl chr 1:156,282,935...156,293,185
G
CDSN
corneodesmosin
involved_in
IMP
(PMID:26014679)
CAFA
PMID:26014679
NCBI chr 6:31,115,087...31,120,446
Ensembl chr 6:31,115,087...31,120,446
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all