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ONTOLOGY REPORT - ANNOTATIONS

Term:keratinization
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Accession:GO:0031424 term browser browse the term
Definition:The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns.


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keratinization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07001416.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 7:132,758,366...132,762,047 JBrowse link
G AABR07033579.3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr11:28,294,843...28,295,058 JBrowse link
G Abca12 ATP binding cassette subfamily A member 12 acts_upstream_of_or_within ISO MGI:3528440|MGI:3809668|MGI:4461044 (PMID:18632686), (PMID:18802465), (PMID:18957418) RGD PMID:18632686 PMID:18802465 PMID:18957418 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049 		JBrowse link
G Cdh3 cadherin 3 involved_in ISO (PMID:22696062) RGD PMID:22696062 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084 		JBrowse link
G Il1a interleukin 1 alpha IDA RGD PMID:20385541 RGD:4142790 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Ivl involucrin involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100 		JBrowse link
G Kazn kazrin, periplakin interacting protein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:154,392,793...155,381,567
Ensembl chr 5:154,392,793...154,779,074 		JBrowse link
G Krt1 keratin 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844 		JBrowse link
G Krt16 keratin 16 involved_in ISO (PMID:11029038) RGD PMID:11029038 NCBI chr10:85,168,357...85,171,816
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt17 keratin 17 acts_upstream_of_or_within ISO MGI:1100845|MGI:1333768 (PMID:15601842) RGD PMID:15601842 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392 		JBrowse link
G Krt2 keratin 2 involved_in ISO
IBA
IEA		 (PMID:12598329)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:12598329 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:132,940,879...132,948,031
Ensembl chr 7:132,940,862...132,947,963 		JBrowse link
G Krt4 keratin 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:133,046,067...133,052,027
Ensembl chr 7:133,046,515...133,052,019 		JBrowse link
G Krt5 keratin 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:132,846,132...132,851,861
Ensembl chr 7:132,846,136...132,851,850 		JBrowse link
G Krt6c keratin 6c involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:132,799,608...132,804,045
Ensembl chr 7:132,799,616...132,804,045 		JBrowse link
G Krt7 keratin 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052 		JBrowse link
G Krt71 keratin 71 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:132,873,532...132,898,975
Ensembl chr 7:132,873,540...132,882,325 		JBrowse link
G Krt72 keratin 72 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:132,910,379...132,920,844
Ensembl chr 7:132,910,613...132,920,783 		JBrowse link
G Krt73 keratin 73 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:132,927,812...132,936,323
Ensembl chr 7:132,928,256...132,936,280 		JBrowse link
G Krt75 keratin 75 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:132,687,101...132,697,360
Ensembl chr 7:132,688,237...132,697,345 		JBrowse link
G Krt76 keratin 76 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:133,016,990...133,025,475
Ensembl chr 7:133,016,992...133,025,496 		JBrowse link
G Krt77 keratin 77 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:132,989,727...133,002,087
Ensembl chr 7:132,989,717...133,002,101 		JBrowse link
G Krt78 keratin 78 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:133,074,193...133,081,536
Ensembl chr 7:133,074,215...133,082,021 		JBrowse link
G Krt79 keratin 79 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:133,056,710...133,067,750
Ensembl chr 7:133,056,709...133,067,705 		JBrowse link
G Krt80 keratin 80 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:132,463,216...132,485,134
Ensembl chr 7:132,463,218...132,485,508 		JBrowse link
G Krt81 keratin 81 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:132,577,112...132,582,238
Ensembl chr 7:132,576,492...132,582,170 		JBrowse link
G Krt82 keratin 82 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:132,665,506...132,675,362
Ensembl chr 7:132,665,292...132,675,489 		JBrowse link
G Krt83 keratin 83 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:132,604,180...132,610,869
Ensembl chr 7:132,604,128...132,610,799 		JBrowse link
G Krt84 keratin 84 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:132,649,064...132,656,885
Ensembl chr 7:132,649,061...132,656,874 		JBrowse link
G Krt85 keratin 85 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:132,630,184...132,637,061
Ensembl chr 7:132,630,058...132,637,049 		JBrowse link
G Krt86 keratin 86 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:132,591,489...132,598,142
Ensembl chr 7:132,591,545...132,598,021 		JBrowse link
G Krt87 keratin 87 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:132,547,388...132,555,005
Ensembl chr 7:132,548,141...132,554,978 		JBrowse link
G Krt90 keratin 90 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:132,677,994...132,686,634
Ensembl chr 7:132,677,751...132,686,759 		JBrowse link
G Krtap6-5 keratin associated protein 6-5 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr11:28,310,977...28,311,204 JBrowse link
G Lce1b late cornified envelope 1B involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,255,351...178,257,533
Ensembl chr 2:178,256,213...178,257,985 		JBrowse link
G Lce1e late cornified envelope 1E involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,462,100...178,463,433
Ensembl chr 2:178,462,100...178,463,433 		JBrowse link
G Lce1f late cornified envelope 1F involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,305,786...178,307,372
Ensembl chr 2:178,305,786...178,307,372 		JBrowse link
G Lce1fl1 late cornified envelope 1F like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,344,421...178,345,204
Ensembl chr 2:178,344,834...178,345,193
Ensembl chr 2:178,344,834...178,345,193 		JBrowse link
G Lce1g late cornified envelope 1G involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 2:178,293,244...178,293,645 JBrowse link
G Lce1m late cornified envelope 1M involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,637,495...178,638,697
Ensembl chr 2:178,637,495...178,638,697 		JBrowse link
G Lce3b late cornified envelope 3B involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,550,333...178,551,454
Ensembl chr 2:178,550,956...178,551,252 		JBrowse link
G Lce3d late cornified envelope 3D involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,589,785...178,590,877
Ensembl chr 2:178,590,377...178,590,673
Ensembl chr 2:178,590,377...178,590,673 		JBrowse link
G Lce3e late cornified envelope 3E involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,578,488...178,579,661
Ensembl chr 2:178,579,162...178,579,458 		JBrowse link
G Lce3el1 late cornified envelope 3E like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,561,990...178,562,532
Ensembl chr 2:178,561,990...178,562,286 		JBrowse link
G Lce3el2 late cornified envelope 3E like 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,597,362...178,598,559
Ensembl chr 2:178,598,016...178,598,312
Ensembl chr 2:178,598,016...178,598,312 		JBrowse link
G Lce3fl1 late cornified envelope 3F-like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,615,562...178,616,788
Ensembl chr 2:178,616,227...178,616,523 		JBrowse link
G Lce7a late cornified envelope 7A involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 2:178,182,848...178,183,135 JBrowse link
G LOC100364321 hypothetical protein LOC100364321 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G LOC102549828 late cornified envelope protein 1E-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,367,227...178,367,774
Ensembl chr 2:178,367,382...178,367,774
Ensembl chr 2:178,367,382...178,367,774 		JBrowse link
G LOC102551936 late cornified envelope protein 1C-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,381,135...178,382,712
Ensembl chr 2:178,381,234...178,381,623
Ensembl chr 2:178,381,234...178,381,623 		JBrowse link
G LOC102552128 late cornified envelope protein 1C-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,322,769...178,323,158
Ensembl chr 2:178,322,769...178,323,158
Ensembl chr 2:178,322,769...178,323,158 		JBrowse link
G LOC103695131 late cornified envelope protein 1C-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,238,080...178,238,853
Ensembl chr 2:178,238,258...178,238,671 		JBrowse link
G LOC108351864 late cornified envelope protein 1C-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G LOC120100586 late cornified envelope protein 1C-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,232,537...178,234,343
Ensembl chr 2:178,232,733...178,233,155 		JBrowse link
G LOC134485747 late cornified envelope protein 3B-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 2:178,542,736...178,543,005 JBrowse link
G LOC134485934 late cornified envelope protein 1A-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 2:178,275,020...178,275,469 JBrowse link
G Sfn stratifin acts_upstream_of_or_within ISO MGI:1861121 (PMID:6174530) RGD PMID:6174530 NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314 		JBrowse link
G Sharpin SHANK-associated RH domain interactor acts_upstream_of_or_within ISO MGI:1856699 (PMID:7792947) RGD PMID:7792947 NCBI chr 7:108,070,681...108,075,012
Ensembl chr 7:108,070,687...108,074,955 		JBrowse link
G Sprr1a small proline-rich protein 1A involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,055,096...178,057,012
Ensembl chr 2:178,055,096...178,057,063 		JBrowse link
G Tgm1 transglutaminase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:29,191,039...29,206,000
Ensembl chr15:29,191,041...29,204,523 		JBrowse link
G Tgm3 transglutaminase 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:117,228,661...117,264,078
Ensembl chr 3:117,228,661...117,264,075 		JBrowse link
cornification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cers3 ceramide synthase 3 involved_in ISO (PMID:22038835) RGD PMID:22038835 NCBI chr 1:120,316,930...120,422,926
Ensembl chr 1:120,318,212...120,422,902 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 acts_upstream_of_or_within ISO MGI:3039046 (PMID:22366455) RGD PMID:22366455 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628 		JBrowse link
G Tmem79 transmembrane protein 79 acts_upstream_of_or_within ISO MGI:1856947 (PMID:24084074) RGD PMID:24084074 NCBI chr 2:173,798,267...173,803,151
Ensembl chr 2:173,798,267...173,803,046 		JBrowse link
negative regulation of cornification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdsn corneodesmosin involved_in ISO (PMID:26014679) RGD PMID:26014679 NCBI chr20:3,179,432...3,184,252
Ensembl chr20:3,179,438...3,184,250 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    multicellular organismal process 8906
      keratinization 64
        cornification + 4
Path 2
Term Annotations click to browse term
  biological_process 20076
    developmental process 7070
      anatomical structure development 6573
        tissue development 2303
          epithelium development 1440
            epithelial cell differentiation 851
              epidermal cell differentiation 256
                keratinocyte differentiation 163
                  keratinization 64
                    cornification + 4
paths to the root