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ONTOLOGY REPORT - ANNOTATIONS


Term:keratinization
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Accession:GO:0031424 term browser browse the term
Definition:The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns.



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keratinization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07012291.1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G AABR07012291.2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G AABR07012299.1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G AABR07012302.1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G AABR07012314.1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G AABR07012317.1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 2:178,344,834...178,345,193 JBrowse link
G AABR07012317.2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G AABR07012318.1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G AABR07012323.1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G AABR07033579.3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr11:28,294,843...28,295,058 JBrowse link
G AABR07033580.1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002
G Abca12 ATP binding cassette subfamily A member 12 acts_upstream_of_or_within ISO MGI:3528440|MGI:3809668|MGI:4461044 (MGI:3807143|PMID:18632686), (MGI:3829841|PMID:18957418), (MGI:4460077|PMID:18802465) RGD PMID:18632686 PMID:18802465 PMID:18957418 MGI:3807143 MGI:3829841 MGI:4460077 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049
JBrowse link
G Cdh3 cadherin 3 involved_in ISO (PMID:22696062) RGD PMID:22696062 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084
JBrowse link
G Il1a interleukin 1 alpha IDA RGD PMID:20385541 RGD:4142790 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Ivl involucrin involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
JBrowse link
G Kazn kazrin, periplakin interacting protein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:154,392,793...155,381,567
Ensembl chr 5:154,392,793...154,779,074
JBrowse link
G Kb15 type II keratin Kb15 acts_upstream_of_or_within ISO MGI:1333768|MGI:96691 (MGI:3525934|PMID:15601842) RGD PMID:15601842 MGI:3525934 NCBI chr 7:132,677,994...132,686,634
Ensembl chr 7:132,677,751...132,686,759
JBrowse link
G Krt16 keratin 16 involved_in ISO (MGI:5613485|PMID:11029038) RGD PMID:11029038 MGI:5613485 NCBI chr10:85,168,357...85,171,744 JBrowse link
G Krt17 keratin 17 acts_upstream_of_or_within ISO MGI:1100845|MGI:1333768 (MGI:3525934|PMID:15601842) RGD PMID:15601842 MGI:3525934 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
JBrowse link
G Krt2 keratin 2 involved_in ISO
IEA
(PMID:12598329)
GO_REF:0000107
RGD
Ensembl
PMID:12598329 GO_REF:0000107 NCBI chr 7:132,941,275...132,947,963
Ensembl chr 7:132,940,862...132,947,963
JBrowse link
G Krtap11-1 keratin associated protein 11-1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr11:28,808,644...28,814,273
Ensembl chr11:28,810,341...28,810,892
JBrowse link
G Krtap13-1 keratin associated protein 13-1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr11:28,043,194...28,044,666
Ensembl chr11:28,044,028...28,044,534
JBrowse link
G Krtap24-1 keratin associated protein 24-1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr11:27,932,015...27,936,047
Ensembl chr11:27,932,785...27,933,531
JBrowse link
G Krtap26-1 keratin associated protein 26-1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr11:27,965,033...27,965,728
Ensembl chr11:27,965,087...27,965,728
JBrowse link
G Lce1f late cornified envelope 1F involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,305,786...178,307,372
Ensembl chr 2:178,305,786...178,307,372
JBrowse link
G Lce1l late cornified envelope 1L involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,462,100...178,463,433
Ensembl chr 2:178,462,100...178,463,433
JBrowse link
G Lce1m late cornified envelope 1M involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,637,495...178,638,697
Ensembl chr 2:178,637,495...178,638,697
JBrowse link
G Lce3e late cornified envelope 3E involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,579,162...178,579,458 JBrowse link
G LOC100363136 hypothetical protein LOC100363136 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr11:28,023,548...28,024,726
Ensembl chr11:28,023,949...28,024,476
JBrowse link
G LOC102552128 late cornified envelope protein 1C-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,322,769...178,323,158
Ensembl chr 2:178,322,769...178,323,158
JBrowse link
G LOC102552326 late cornified envelope protein 5A-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 2:178,275,020...178,275,469 JBrowse link
G LOC108350059 small proline-rich protein 2B involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:177,719,576...177,719,845
Ensembl chr 2:177,719,576...177,719,845
JBrowse link
G Sfn stratifin acts_upstream_of_or_within ISO MGI:1861121 (MGI:55181|PMID:6174530) RGD PMID:6174530 MGI:55181 Ensembl chr 5:145,826,201...145,831,314 JBrowse link
G Sharpin SHANK-associated RH domain interactor acts_upstream_of_or_within ISO MGI:1856699 (MGI:75289|PMID:7792947) RGD PMID:7792947 MGI:75289 NCBI chr 7:108,070,681...108,075,012
Ensembl chr 7:108,070,687...108,074,955
JBrowse link
G Sprr1a small proline-rich protein 1A involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,055,096...178,057,012
Ensembl chr 2:178,055,096...178,057,063
JBrowse link
G Sprr2b small proline rich protein 2B involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:177,852,824...177,853,096
Ensembl chr 2:177,852,824...177,853,096
JBrowse link
G Sprr2d small proline-rich protein 2D involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:177,870,082...177,870,679
Ensembl chr 2:177,870,434...177,870,679
JBrowse link
G Sprr2g small proline rich protein 2G involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G Tgm1 transglutaminase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:29,191,039...29,206,000
Ensembl chr15:29,191,041...29,204,523
JBrowse link
G Tgm3 transglutaminase 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:117,228,661...117,264,078
Ensembl chr 3:117,228,661...117,264,075
JBrowse link
cornification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp14 caspase 14 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:10,929,759...10,932,591
Ensembl chr 7:10,926,725...10,933,405
JBrowse link
G Cers3 ceramide synthase 3 involved_in ISO (MGI:5303015|PMID:22038835) RGD PMID:22038835 MGI:5303015 NCBI chr 1:120,316,930...120,422,926
Ensembl chr 1:120,318,212...120,422,902
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 acts_upstream_of_or_within ISO MGI:3039046 (MGI:5466369|PMID:22366455) RGD PMID:22366455 MGI:5466369 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Tmem79 transmembrane protein 79 acts_upstream_of_or_within ISO MGI:1856947 (MGI:5519142|PMID:24084074) RGD PMID:24084074 MGI:5519142 NCBI chr 2:173,798,267...173,803,151
Ensembl chr 2:173,798,267...173,803,046
JBrowse link
negative regulation of cornification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdsn corneodesmosin involved_in ISO (PMID:26014679) RGD PMID:26014679 NCBI chr20:3,179,432...3,185,854
Ensembl chr20:3,179,438...3,184,250
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    multicellular organismal process 8976
      keratinization 45
        cornification + 5
Path 2
Term Annotations click to browse term
  biological_process 19497
    developmental process 6889
      anatomical structure development 6306
        multicellular organism development 5727
          system development 5373
            animal organ development 4130
              skin development 297
                keratinocyte differentiation 130
                  keratinization 45
                    cornification + 5
paths to the root