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ONTOLOGY REPORT - ANNOTATIONS


Term:keratinization
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Accession:GO:0031424 term browser browse the term
Definition:The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns.



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keratinization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 2210017I01Rik RIKEN cDNA 2210017I01 gene involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 2:178,182,848...178,183,135 JBrowse link
G AABR07001416.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 7:132,758,366...132,762,047 JBrowse link
G AABR07033579.3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr11:28,294,843...28,295,058 JBrowse link
G Abca12 ATP binding cassette subfamily A member 12 acts_upstream_of_or_within ISO MGI:3528440|MGI:3809668|MGI:4461044 (MGI:3807143|PMID:18632686), (MGI:3829841|PMID:18957418), (MGI:4460077|PMID:18802465) RGD PMID:18632686 PMID:18802465 PMID:18957418 MGI:3807143 MGI:3829841 MGI:4460077 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049
JBrowse link
G Cdh3 cadherin 3 involved_in ISO (PMID:22696062) RGD PMID:22696062 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084
JBrowse link
G ENSRNOG00000063139 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 2:178,356,168...178,356,557 JBrowse link
G ENSRNOG00000066407 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 2:178,542,736...178,543,005 JBrowse link
G ENSRNOG00000071041 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr11:28,310,977...28,311,204 JBrowse link
G Il1a interleukin 1 alpha IDA RGD PMID:20385541 RGD:4142790 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Ivl involucrin involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
JBrowse link
G Kazn kazrin, periplakin interacting protein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:154,392,793...155,381,567
Ensembl chr 5:154,392,793...154,779,074
JBrowse link
G Krt1 keratin 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844
JBrowse link
G Krt16 keratin 16 involved_in ISO (MGI:5613485|PMID:11029038) RGD PMID:11029038 MGI:5613485 NCBI chr10:85,168,357...85,171,744
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt17 keratin 17 acts_upstream_of_or_within ISO MGI:1100845|MGI:1333768 (MGI:3525934|PMID:15601842) RGD PMID:15601842 MGI:3525934 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
JBrowse link
G Krt2 keratin 2 involved_in ISO
IBA
IEA
(PMID:12598329)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:12598329 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 7:132,941,275...132,947,963
Ensembl chr 7:132,940,862...132,947,963
JBrowse link
G Krt4 keratin 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:133,046,067...133,052,027
Ensembl chr 7:133,046,515...133,052,019
JBrowse link
G Krt5 keratin 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,846,355...132,851,986
Ensembl chr 7:132,846,136...132,851,850
JBrowse link
G Krt7 keratin 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,528,863...132,545,052
Ensembl chr 7:132,528,895...132,545,052
JBrowse link
G Krt71 keratin 71 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,873,532...132,898,975
Ensembl chr 7:132,873,540...132,882,325
JBrowse link
G Krt72 keratin 72 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,910,379...132,920,844
Ensembl chr 7:132,910,613...132,920,783
JBrowse link
G Krt73 keratin 73 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,927,812...132,936,323
Ensembl chr 7:132,928,256...132,936,280
JBrowse link
G Krt75 keratin 75 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,687,101...132,697,360
Ensembl chr 7:132,688,237...132,697,345
JBrowse link
G Krt76 keratin 76 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:133,016,990...133,025,414
Ensembl chr 7:133,016,992...133,025,496
JBrowse link
G Krt77 keratin 77 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,989,727...133,002,087
Ensembl chr 7:132,989,717...133,002,101
JBrowse link
G Krt78 keratin 78 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:133,074,193...133,081,536
Ensembl chr 7:133,074,215...133,082,021
JBrowse link
G Krt79 keratin 79 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:133,056,710...133,067,750
Ensembl chr 7:133,056,709...133,067,705
JBrowse link
G Krt8 keratin 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Krt80 keratin 80 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,464,807...132,485,026
Ensembl chr 7:132,463,218...132,485,508
JBrowse link
G Krt81 keratin 81 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,577,112...132,582,238
Ensembl chr 7:132,576,492...132,582,170
JBrowse link
G Krt82 keratin 82 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,665,506...132,675,362
Ensembl chr 7:132,665,292...132,675,489
JBrowse link
G Krt83 keratin 83 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,604,180...132,610,869
Ensembl chr 7:132,604,128...132,610,799
JBrowse link
G Krt84 keratin 84 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,649,064...132,656,885
Ensembl chr 7:132,649,061...132,656,874
JBrowse link
G Krt85 keratin 85 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,630,184...132,636,988
Ensembl chr 7:132,630,058...132,637,049
JBrowse link
G Krt86 keratin 86 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,591,489...132,598,142
Ensembl chr 7:132,591,545...132,598,021
JBrowse link
G Krt87 keratin 87 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,547,388...132,554,978
Ensembl chr 7:132,548,141...132,554,978
JBrowse link
G Krt88 keratin 88 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,566,087...132,571,946
Ensembl chr 7:132,561,724...132,571,944
JBrowse link
G Krt90 keratin 90 acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:1333768|MGI:96691 (MGI:3525934|PMID:15601842)
PMID:21873635
RGD PMID:15601842 PMID:21873635 MGI:3525934, RGD:13792537 NCBI chr 7:132,677,994...132,686,634
Ensembl chr 7:132,677,751...132,686,759
JBrowse link
G Lce1f late cornified envelope 1F involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,305,786...178,307,372
Ensembl chr 2:178,305,786...178,307,372
JBrowse link
G Lce1g late cornified envelope 1G involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 2:178,293,244...178,293,645 JBrowse link
G Lce1l late cornified envelope 1L involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,462,100...178,463,433
Ensembl chr 2:178,462,100...178,463,433
JBrowse link
G Lce1m late cornified envelope 1M involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,637,495...178,638,697
Ensembl chr 2:178,637,495...178,638,697
JBrowse link
G Lce3d late cornified envelope 3D involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,550,187...178,551,541
Ensembl chr 2:178,550,956...178,551,252
JBrowse link
G Lce3e late cornified envelope 3E involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,579,162...178,579,458
Ensembl chr 2:178,579,162...178,579,458
JBrowse link
G Lce3fl1 late cornified envelope 3F-like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,616,227...178,616,735
Ensembl chr 2:178,616,227...178,616,523
JBrowse link
G LOC100911982 late cornified envelope protein 3C-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,590,377...178,590,673
Ensembl chr 2:178,590,377...178,590,673
JBrowse link
G LOC102549828 late cornified envelope protein 1E-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,367,227...178,367,774
Ensembl chr 2:178,367,382...178,367,774
JBrowse link
G LOC102551936 late cornified envelope protein 1C-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,381,135...178,382,712
Ensembl chr 2:178,381,234...178,381,623
JBrowse link
G LOC102552128 late cornified envelope protein 1C-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,322,769...178,323,158
Ensembl chr 2:178,322,769...178,323,158
JBrowse link
G LOC102552326 late cornified envelope protein 5A-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 2:178,275,020...178,275,469 JBrowse link
G LOC103691629 uncharacterized LOC103691629 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,344,421...178,345,204
Ensembl chr 2:178,344,834...178,345,193
JBrowse link
G LOC120100586 late cornified envelope protein 1C-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,232,537...178,234,343
Ensembl chr 2:178,232,733...178,233,155
JBrowse link
G LOC120100587 late cornified envelope protein 1B-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,255,351...178,257,533
Ensembl chr 2:178,256,213...178,257,985
JBrowse link
G LOC120100588 late cornified envelope protein 3D-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,561,990...178,562,532
Ensembl chr 2:178,561,990...178,562,286
JBrowse link
G LOC120100589 late cornified envelope protein 3D-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,598,016...178,598,428
Ensembl chr 2:178,598,016...178,598,312
JBrowse link
G LOC683313 similar to keratin complex 2, basic, gene 6a involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,799,608...132,804,045
Ensembl chr 7:132,799,616...132,804,045
JBrowse link
G Sfn stratifin acts_upstream_of_or_within ISO MGI:1861121 (MGI:55181|PMID:6174530) RGD PMID:6174530 MGI:55181 Ensembl chr 5:145,826,201...145,831,314 JBrowse link
G Sharpin SHANK-associated RH domain interactor acts_upstream_of_or_within ISO MGI:1856699 (MGI:75289|PMID:7792947) RGD PMID:7792947 MGI:75289 NCBI chr 7:108,070,681...108,075,012
Ensembl chr 7:108,070,687...108,074,955
JBrowse link
G Sprr1a small proline-rich protein 1A involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,055,096...178,057,012
Ensembl chr 2:178,055,096...178,057,063
JBrowse link
G Tgm1 transglutaminase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:29,191,039...29,206,000
Ensembl chr15:29,191,041...29,204,523
JBrowse link
G Tgm3 transglutaminase 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:117,228,661...117,264,078
Ensembl chr 3:117,228,661...117,264,075
JBrowse link
cornification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp14 caspase 14 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:10,929,759...10,932,591
Ensembl chr 7:10,926,725...10,933,405
JBrowse link
G Cers3 ceramide synthase 3 involved_in ISO (MGI:5303015|PMID:22038835) RGD PMID:22038835 MGI:5303015 NCBI chr 1:120,316,930...120,422,926
Ensembl chr 1:120,318,212...120,422,902
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 acts_upstream_of_or_within ISO MGI:3039046 (MGI:5466369|PMID:22366455) RGD PMID:22366455 MGI:5466369 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Tmem79 transmembrane protein 79 acts_upstream_of_or_within ISO MGI:1856947 (MGI:5519142|PMID:24084074) RGD PMID:24084074 MGI:5519142 NCBI chr 2:173,798,267...173,803,151
Ensembl chr 2:173,798,267...173,803,046
JBrowse link
negative regulation of cornification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdsn corneodesmosin involved_in ISO (PMID:26014679) RGD PMID:26014679 NCBI chr20:3,179,432...3,185,854
Ensembl chr20:3,179,438...3,184,250
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20026
    multicellular organismal process 9021
      keratinization 65
        cornification + 5
Path 2
Term Annotations click to browse term
  biological_process 20026
    developmental process 7035
      anatomical structure development 6470
        tissue development 2224
          epithelium development 1390
            epithelial cell differentiation 815
              epidermal cell differentiation 245
                keratinocyte differentiation 157
                  keratinization 65
                    cornification + 5
paths to the root