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ONTOLOGY REPORT - ANNOTATIONS


Term:replication fork processing
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Accession:GO:0031297 term browser browse the term
Definition:The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes.
Synonyms:exact_synonym: collapsed replication fork processing;   recovery from replication fork arrest;   recovery from replication fork stalling
 narrow_synonym: recovery from replication fork arrest at rDNA locus;   recovery from replication fork stalling at rDNA locus;   replication fork processing at rDNA locus;   replication fork processing at ribosomal DNA locus
 related_synonym: replication fork restart;   replication restart
 alt_id: GO:0034065


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replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alyref Aly/REF export factor involved_in ISO (PMID:22144908) UniProt PMID:22144908 NCBI chrNW_004936594:5,398,973...5,402,846 JBrowse link
G Atr ATR serine/threonine kinase involved_in ISO (MGI:6467697|PMID:29125140) UniProt PMID:29125140 MGI:6467697 NCBI chrNW_004936540:4,074,543...4,178,859 JBrowse link
G Atrx ATRX chromatin remodeler involved_in ISO (MGI:5568153|PMID:24651726) UniProt PMID:24651726 MGI:5568153 NCBI chrNW_004936683:2,496,307...2,718,539 JBrowse link
G Blm BLM RecQ like helicase involved_in ISO (PMID:17115688)
(MGI:6467697|PMID:29125140)
UniProt PMID:17115688 PMID:29125140 MGI:6467697 NCBI chrNW_004936483:16,194,092...16,295,803 JBrowse link
G Bod1l1 biorientation of chromosomes in cell division 1 like 1 involved_in ISO (PMID:26166705) UniProt PMID:26166705 NCBI chrNW_004936477:13,927,605...13,975,722 JBrowse link
G Cdk9 cyclin dependent kinase 9 involved_in ISO (PMID:20930849) UniProt PMID:20930849 NCBI chrNW_004936487:15,446,864...15,450,750 JBrowse link
G Cenpx centromere protein X involved_in ISO (PMID:20347428) UniProt PMID:20347428 NCBI chrNW_004936594:5,517,665...5,520,606 JBrowse link
G Ddx11 DEAD/H-box helicase 11 involved_in ISO (PMID:26503245) UniProt PMID:26503245 NCBI chrNW_004936606:181,457...209,286 JBrowse link
G Etaa1 ETAA1 activator of ATR kinase involved_in ISO (PMID:27723717), (PMID:27723720) UniProt PMID:27723717 PMID:27723720 NCBI chrNW_004936491:11,962,161...11,975,164 JBrowse link
G Exd2 exonuclease 3'-5' domain containing 2 involved_in ISO (PMID:31255466) UniProt PMID:31255466 NCBI chrNW_004936495:12,432,752...12,479,807 JBrowse link
G Fam111a FAM111 trypsin like peptidase A involved_in ISO (PMID:32165630) UniProt PMID:32165630 NCBI chrNW_004936581:3,482,649...3,488,331 JBrowse link
G Fancm FA complementation group M involved_in ISO (PMID:20347428) UniProt PMID:20347428 NCBI chrNW_004936583:4,085,802...4,145,621 JBrowse link
G Fbh1 F-box DNA helicase 1 involved_in ISO (PMID:25585578)
(MGI:5566975|PMID:24108124)
UniProt PMID:24108124 PMID:25585578 MGI:5566975 NCBI chrNW_004936484:8,635,752...8,689,949 JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease involved_in ISO (PMID:26578604) UniProt PMID:26578604 NCBI chrNW_004936493:13,157,114...13,182,797 JBrowse link
G LOC101956664 TRAF interacting protein involved_in ISO (PMID:27462463)
(PMID:26711499)
UniProt PMID:26711499 PMID:27462463 NCBI chrNW_004936529:1,434,629...1,466,382 JBrowse link
G LOC101962206 histone-lysine N-methyltransferase SETMAR involved_in ISO (PMID:20457750), (PMID:22231448), (PMID:24573677) UniProt PMID:20457750 PMID:22231448 PMID:24573677 NCBI chrNW_004936577:3,761,078...3,771,864 JBrowse link
G LOC101968899 oocyte expressed protein involved_in ISO (MGI:6467697|PMID:29125140) UniProt PMID:29125140 MGI:6467697 NCBI chrNW_004937318:2,623...3,622 JBrowse link
G Mms22l MMS22 like, DNA repair protein involved_in ISO (PMID:21055983), (PMID:21055984), (PMID:21055985) UniProt PMID:21055983 PMID:21055984 PMID:21055985 NCBI chrNW_004936699:486,510...608,532 JBrowse link
G Nucks1 nuclear casein kinase and cyclin dependent kinase substrate 1 involved_in ISO (PMID:26323318) ParkinsonsUK-UCL PMID:26323318 NCBI chrNW_004936557:6,713,065...6,728,011 JBrowse link
G Pcna proliferating cell nuclear antigen involved_in ISO (MGI:5522574|PMID:24115439) BHF-UCL PMID:24115439 MGI:5522574 NCBI chrNW_004936485:13,766,221...13,771,215 JBrowse link
G Primpol primase and DNA directed polymerase involved_in ISO (PMID:28534480)
(PMID:24240614), (PMID:24267451)
UniProt PMID:24240614 PMID:24267451 PMID:28534480 NCBI chrNW_004936554:4,536,246...4,571,000 JBrowse link
G Rad51 RAD51 recombinase involved_in
acts_upstream_of_or_within
ISO (PMID:25585578)
(MGI:5442243|PMID:22778135)
(PMID:22778135)
UniProt
MGI
BHF-UCL
PMID:22778135 PMID:25585578 MGI:5442243 NCBI chrNW_004936471:4,119,020...4,136,811 JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO (PMID:26474068) UniProt PMID:26474068 NCBI chrNW_004936475:23,544,974...23,586,716 JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5522574|PMID:24115439) BHF-UCL PMID:24115439 MGI:5522574 NCBI chrNW_004936514:10,920,979...10,954,483 JBrowse link
G Smarcal1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 involved_in ISO (PMID:19793862) UniProt PMID:19793862 NCBI chrNW_004936586:828,661...887,988 JBrowse link
G Thoc1 THO complex 1 involved_in ISO (PMID:22144908) UniProt PMID:22144908 NCBI chrNW_004936550:590,119...638,152 JBrowse link
G Tonsl tonsoku like, DNA repair protein involved_in ISO (PMID:21055983), (PMID:21055984), (PMID:21055985) UniProt PMID:21055983 PMID:21055984 PMID:21055985 NCBI chrNW_004936470:7,817,444...7,829,124 JBrowse link
G Wrn WRN RecQ like helicase involved_in ISO (PMID:12882351)
(PMID:17115688)
UniProt PMID:12882351 PMID:17115688 NCBI chrNW_004936792:862,659...1,005,065 JBrowse link
G Zranb3 zinc finger RANBP2-type containing 3 involved_in ISO (PMID:22704558), (PMID:22705370) UniProt PMID:22704558 PMID:22705370 NCBI chrNW_004936469:40,328,850...40,558,797 JBrowse link
DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mre11 MRE11 homolog, double strand break repair nuclease involved_in ISO (PMID:29670289) UniProt PMID:29670289 NCBI chrNW_004936674:466,495...528,072 JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO (PMID:28834754), (PMID:29670289) UniProt PMID:28834754 PMID:29670289 NCBI chrNW_004936561:4,180,607...4,238,623 JBrowse link
mitotic recombination-dependent replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2 DNA repair associated involved_in ISO (PMID:21076401) BHF-UCL PMID:21076401 NCBI chrNW_004936472:26,945,659...27,017,693 JBrowse link
regulation of DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Znf365 zinc finger protein 365 involved_in ISO (PMID:23966166) UniProt PMID:23966166 NCBI chrNW_004936614:833,665...853,547 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12170
    metabolic process 7645
      cellular metabolic process 7015
        cellular macromolecule metabolic process 5419
          DNA metabolic process 669
            DNA-dependent DNA replication maintenance of fidelity 37
              replication fork processing 33
                DNA strand resection involved in replication fork processing + 3
                mitotic recombination-dependent replication fork processing + 1
                negative regulation of mitotic recombination involved in replication fork processing 0
                replication fork reversal 0
                stalled replication fork localization to nuclear periphery 0
Path 2
Term Annotations click to browse term
  biological_process 12170
    metabolic process 7645
      organic substance metabolic process 7370
        organic substance biosynthetic process 3864
          macromolecule biosynthetic process 3190
            cellular macromolecule biosynthetic process 3151
              DNA replication 188
                DNA-dependent DNA replication 108
                  DNA-dependent DNA replication maintenance of fidelity 37
                    replication fork processing 33
                      DNA strand resection involved in replication fork processing + 3
                      mitotic recombination-dependent replication fork processing + 1
                      negative regulation of mitotic recombination involved in replication fork processing 0
                      replication fork reversal 0
                      stalled replication fork localization to nuclear periphery 0
paths to the root