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ONTOLOGY REPORT - ANNOTATIONS


Term:replication fork processing
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Accession:GO:0031297 term browser browse the term
Definition:The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes.
Synonyms:exact_synonym: collapsed replication fork processing;   recovery from replication fork arrest;   recovery from replication fork stalling
 narrow_synonym: recovery from replication fork arrest at rDNA locus;   recovery from replication fork stalling at rDNA locus;   replication fork processing at rDNA locus;   replication fork processing at ribosomal DNA locus
 related_synonym: replication fork restart;   replication restart
 alt_id: GO:0034065



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replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APITD1 apoptosis-inducing, TAF9-like domain 1 involved_in IEA
IBA
Ensembl
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:70,700,802...70,711,719
Ensembl chr 6:70,701,694...70,711,717
JBrowse link
G ASF1A anti-silencing function 1A histone chaperone involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:43,200,339...43,215,019
Ensembl chr 1:43,200,415...43,214,913
JBrowse link
G ATR ATR serine/threonine kinase involved_in ISO (MGI:6467697|PMID:29125140) UniProt PMID:29125140 MGI:6467697 NCBI chr13:83,175,515...83,289,986
Ensembl chr13:83,174,824...83,289,989
JBrowse link
G ATRX ATRX chromatin remodeler involved_in IEA
IBA
Ensembl
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:61,584,028...61,872,341
Ensembl chr  X:61,584,848...61,872,287
JBrowse link
G BLM BLM RecQ like helicase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:53,317,515...53,412,649
Ensembl chr 7:53,317,540...53,412,645
JBrowse link
G BOD1 biorientation of chromosomes in cell division 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:50,734,510...50,743,417 JBrowse link
G BOD1L1 biorientation of chromosomes in cell division 1 like 1 involved_in IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr 8:9,197,064...9,254,422
Ensembl chr 8:9,197,043...9,254,485
JBrowse link
G BRCA2 BRCA2 DNA repair associated involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14681210) Ensembl
MGI
PMID:14681210 GO_REF:0000107 NCBI chr11:8,805,950...8,858,128
Ensembl chr11:8,805,953...8,858,418
JBrowse link
G CDK9 cyclin dependent kinase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:268,277,083...268,280,493
Ensembl chr 1:268,276,841...268,281,052
JBrowse link
G CENPX centromere protein X involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:991,618...994,849 JBrowse link
G DDX11 DEAD/H-box helicase 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:67,359,399...67,395,739
Ensembl chr 5:67,364,877...67,395,730
JBrowse link
G DONSON DNA replication fork stabilization factor DONSON involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:197,192,661...197,204,243
Ensembl chr13:197,193,658...197,203,932
JBrowse link
G EME1 essential meiotic structure-specific endonuclease 1 involved_in IEA
IBA
Ensembl
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr12:26,670,126...26,680,097
Ensembl chr12:26,670,176...26,680,601
JBrowse link
G EME2 essential meiotic structure-specific endonuclease subunit 2 involved_in IEA
IBA
Ensembl
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:40,190,545...40,193,994
Ensembl chr 3:40,186,846...40,193,957
JBrowse link
G ETAA1 ETAA1 activator of ATR kinase involved_in IEA
IBA
Ensembl
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:74,721,313...74,736,784
Ensembl chr 3:74,724,291...74,736,764
JBrowse link
G EXD2 exonuclease 3'-5' domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:92,847,958...92,909,044
Ensembl chr 7:92,848,032...92,913,771
JBrowse link
G FAM111A FAM111 trypsin like peptidase A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:12,250,529...12,263,497
Ensembl chr 2:12,250,538...12,260,985
JBrowse link
G FANCM FA complementation group M involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:175,333,965...175,402,065
Ensembl chr 1:175,334,141...175,400,685
JBrowse link
G FBH1 F-box DNA helicase 1 involved_in IEA
IBA
Ensembl
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr10:65,060,714...65,108,975
Ensembl chr10:65,060,312...65,108,379
JBrowse link
G GEN1 GEN1 Holliday junction 5' flap endonuclease involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:120,067,792...120,097,305
Ensembl chr 3:120,065,973...120,097,056
JBrowse link
G KHDC3L KH domain containing 3 like, subcortical maternal complex member involved_in ISO (MGI:6467697|PMID:29125140) UniProt PMID:29125140 MGI:6467697 NCBI chr 1:52,996,706...52,999,074 JBrowse link
G LOC100514009 histone-lysine N-methyltransferase SETMAR involved_in ISO (PMID:20457750), (PMID:22231448), (PMID:24573677) UniProt PMID:20457750 PMID:22231448 PMID:24573677 NCBI chr13:60,914,412...60,933,064 JBrowse link
G MMS22L MMS22 like, DNA repair protein involved_in IEA InterPro
TreeGrafter
Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:64,306,078...64,459,956
Ensembl chr 1:64,306,073...64,459,904
JBrowse link
G MUS81 MUS81 structure-specific endonuclease subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:6,462,825...6,470,780
Ensembl chr 2:6,463,413...6,469,112
JBrowse link
G NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:66,398,845...66,435,548
Ensembl chr 9:66,398,227...66,435,517
JBrowse link
G OOEP oocyte expressed protein involved_in ISO (MGI:6467697|PMID:29125140) UniProt PMID:29125140 MGI:6467697 NCBI chr 1:53,006,898...53,007,877
Ensembl chr 1:53,006,761...53,007,877
JBrowse link
G PCNA proliferating cell nuclear antigen involved_in ISO (MGI:5522574|PMID:24115439) BHF-UCL PMID:24115439 MGI:5522574 NCBI chr17:14,137,746...14,142,584
Ensembl chr17:14,136,886...14,142,744
JBrowse link
G POLQ DNA polymerase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:138,962,634...139,108,499
Ensembl chr13:138,978,609...139,108,500
JBrowse link
G PRIMPOL primase and DNA directed polymerase involved_in IEA
IBA
Ensembl
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr15:45,764,261...45,851,052
Ensembl chr15:45,709,710...45,819,919
JBrowse link
G RAD51 RAD51 recombinase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22778135) Ensembl
MGI
PMID:22778135 GO_REF:0000107 NCBI chr 1:130,592,414...130,640,326
Ensembl chr 1:130,586,665...130,640,136
JBrowse link
G RECQL RecQ like helicase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:51,953,460...51,995,619
Ensembl chr 5:51,953,451...52,003,740
JBrowse link
G RFWD3 ring finger and WD repeat domain 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:12,952,243...12,994,053
Ensembl chr 6:12,952,253...12,994,052
JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:62,611,844...62,636,628
Ensembl chr17:62,611,909...62,634,690
JBrowse link
G SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 involved_in IEA
IBA
Ensembl
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr15:118,627,734...118,688,005
Ensembl chr15:118,627,467...118,688,397
JBrowse link
G TIPIN TIMELESS interacting protein involved_in IEA InterPro
UniProt
GO_REF:0000002 GO_REF:0000104 NCBI chr 1:164,349,196...164,369,297
Ensembl chr 1:164,350,705...164,369,223
JBrowse link
G TONSL tonsoku like, DNA repair protein involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 4:349,992...361,749
Ensembl chr 4:350,060...362,167
JBrowse link
G TRAIP TRAF interacting protein involved_in IEA
IBA
Ensembl
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr13:32,332,336...32,380,988
Ensembl chr13:32,345,599...32,379,766
JBrowse link
G WRN WRN RecQ like helicase involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:53,966,968...54,094,855
Ensembl chr15:53,966,986...54,094,587
JBrowse link
G ZRANB3 zinc finger RANBP2-type containing 3 involved_in IEA
IBA
Ensembl
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr15:16,414,291...16,727,659
Ensembl chr15:16,414,757...16,727,841
JBrowse link
DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EXO1 exonuclease 1 involved_in ISO (PMID:26240375) UniProt PMID:26240375 NCBI chr10:15,317,555...15,360,593
Ensembl chr10:15,317,581...15,359,839
JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,572,352...26,634,596
Ensembl chr 9:26,572,361...26,634,567
JBrowse link
G NBN nibrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:46,787,664...46,854,331
Ensembl chr 4:46,787,691...46,874,603
JBrowse link
G RAD50 RAD50 double strand break repair protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:134,844,460...134,939,188
Ensembl chr 2:134,700,817...134,939,189
JBrowse link
G RBBP8 RB binding protein 8, endonuclease involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:107,923,921...108,020,067
Ensembl chr 6:107,924,002...108,022,669
JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:40,117,348...40,171,935
Ensembl chr17:40,107,462...40,171,878
JBrowse link
mitotic recombination-dependent replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCA2 BRCA2 DNA repair associated involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:8,805,950...8,858,128
Ensembl chr11:8,805,953...8,858,418
JBrowse link
G RAD51 RAD51 recombinase involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:130,592,414...130,640,326
Ensembl chr 1:130,586,665...130,640,136
JBrowse link
negative regulation of DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DYNLL1 dynein light chain LC8-type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:40,455,954...40,458,352
Ensembl chr14:40,455,985...40,459,104
JBrowse link
regulation of DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZNF365 zinc finger protein 365 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr14:65,861,398...65,888,341
Ensembl chr14:65,861,564...65,888,335
JBrowse link
replication fork reversal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARM1 coactivator associated arginine methyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:69,602,121...69,644,862
Ensembl chr 2:69,602,136...69,644,854
JBrowse link
G DNA2 DNA replication helicase/nuclease 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:71,550,405...71,607,067
Ensembl chr14:71,552,121...71,610,740
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:14,203,157...14,241,164
Ensembl chr10:14,203,160...14,241,196
JBrowse link
G SLC25A16 solute carrier family 25 member 16 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:71,612,273...71,651,341
Ensembl chr14:71,610,475...71,651,102
JBrowse link
G ZRANB3 zinc finger RANBP2-type containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:16,414,291...16,727,659
Ensembl chr15:16,414,757...16,727,841
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17799
    metabolic process 10358
      primary metabolic process 9009
        nucleobase-containing compound metabolic process 5148
          nucleic acid metabolic process 4652
            DNA metabolic process 926
              DNA-templated DNA replication maintenance of fidelity 57
                replication fork processing 51
                  DNA strand resection involved in replication fork processing + 8
                  mitotic recombination-dependent replication fork processing + 2
                  replication fork reversal 5
                  stalled replication fork localization to nuclear periphery 0
Path 2
Term Annotations click to browse term
  biological_process 17799
    metabolic process 10358
      organic substance metabolic process 9930
        organic cyclic compound metabolic process 5601
          nucleobase-containing compound metabolic process 5148
            nucleic acid metabolic process 4652
              DNA metabolic process 926
                DNA replication 263
                  DNA-templated DNA replication 154
                    DNA-templated DNA replication maintenance of fidelity 57
                      replication fork processing 51
                        DNA strand resection involved in replication fork processing + 8
                        mitotic recombination-dependent replication fork processing + 2
                        replication fork reversal 5
                        stalled replication fork localization to nuclear periphery 0
paths to the root