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ONTOLOGY REPORT - ANNOTATIONS


Term:replication fork processing
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Accession:GO:0031297 term browser browse the term
Definition:The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes.
Synonyms:exact_synonym: collapsed replication fork processing;   recovery from replication fork arrest;   recovery from replication fork stalling
 narrow_synonym: recovery from replication fork arrest at rDNA locus;   recovery from replication fork stalling at rDNA locus;   replication fork processing at rDNA locus;   replication fork processing at ribosomal DNA locus
 related_synonym: replication fork restart;   replication restart
 alt_id: GO:0034065


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replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALYREF Aly/REF export factor involved_in ISO (PMID:22144908) UniProt PMID:22144908 NCBI chr12:1,099,239...1,103,058
Ensembl chr12:1,091,976...1,103,054
JBrowse link
G APITD1 apoptosis-inducing, TAF9-like domain 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:70,700,802...70,711,719
Ensembl chr 6:70,701,694...70,711,717
JBrowse link
G ATR ATR serine/threonine kinase involved_in ISO (MGI:6467697|PMID:29125140) UniProt PMID:29125140 MGI:6467697 NCBI chr13:83,175,515...83,289,986
Ensembl chr13:83,174,824...83,289,923
JBrowse link
G ATRX ATRX chromatin remodeler involved_in ISO (MGI:5568153|PMID:24651726) UniProt PMID:24651726 MGI:5568153 NCBI chr  X:61,584,028...61,872,341
Ensembl chr  X:61,584,848...61,872,288
JBrowse link
G BLM BLM RecQ like helicase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:53,317,515...53,412,649
Ensembl chr 7:53,317,540...53,412,647
JBrowse link
G BOD1L1 biorientation of chromosomes in cell division 1 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:9,197,064...9,254,422
Ensembl chr 8:9,197,036...9,254,386
JBrowse link
G CDK9 cyclin dependent kinase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:268,277,083...268,280,493
Ensembl chr 1:268,275,891...268,281,057
JBrowse link
G CENPX centromere protein X involved_in ISO (PMID:20347428) UniProt PMID:20347428 NCBI chr12:991,618...994,849 JBrowse link
G DDX11 DEAD/H-box helicase 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:67,359,399...67,395,739
Ensembl chr 5:67,321,132...67,397,111
JBrowse link
G EME1 essential meiotic structure-specific endonuclease 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:26,670,126...26,680,097
Ensembl chr12:26,670,176...26,680,601
JBrowse link
G EME2 essential meiotic structure-specific endonuclease subunit 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:40,190,545...40,193,994
Ensembl chr 3:40,186,846...40,193,957
JBrowse link
G ETAA1 ETAA1 activator of ATR kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:74,721,313...74,736,784
Ensembl chr 3:74,721,069...74,736,764
JBrowse link
G EXD2 exonuclease 3'-5' domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:92,847,958...92,909,044
Ensembl chr 7:92,848,116...92,913,771
JBrowse link
G FAM111A FAM111 trypsin like peptidase A involved_in ISO (PMID:32165630) UniProt PMID:32165630 NCBI chr 2:12,250,529...12,263,497
Ensembl chr 2:12,250,155...12,260,985
JBrowse link
G FANCM FA complementation group M involved_in ISO (PMID:20347428) UniProt PMID:20347428 NCBI chr 1:175,333,965...175,402,065
Ensembl chr 1:175,334,047...175,445,650
JBrowse link
G FBH1 F-box DNA helicase 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr10:65,060,714...65,108,975
Ensembl chr10:64,955,189...65,108,380
JBrowse link
G GEN1 GEN1 Holliday junction 5' flap endonuclease involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:120,067,792...120,097,305
Ensembl chr 3:120,065,973...120,097,069
JBrowse link
G KHDC3L KH domain containing 3 like, subcortical maternal complex member involved_in ISO (MGI:6467697|PMID:29125140) UniProt PMID:29125140 MGI:6467697 NCBI chr 1:52,996,706...52,999,074 JBrowse link
G LOC100514009 histone-lysine N-methyltransferase SETMAR involved_in ISO (PMID:20457750), (PMID:22231448), (PMID:24573677) UniProt PMID:20457750 PMID:22231448 PMID:24573677 NCBI chr13:60,914,412...60,933,064 JBrowse link
G MMS22L MMS22 like, DNA repair protein involved_in IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr 1:64,306,078...64,459,956
Ensembl chr 1:64,303,604...64,459,933
JBrowse link
G NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:66,398,845...66,435,548
Ensembl chr 9:66,398,227...66,435,577
JBrowse link
G OOEP oocyte expressed protein involved_in ISO (MGI:6467697|PMID:29125140) UniProt PMID:29125140 MGI:6467697 NCBI chr 1:53,006,898...53,007,877
Ensembl chr 1:53,006,685...53,007,885
JBrowse link
G PCNA proliferating cell nuclear antigen involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,137,746...14,142,584
Ensembl chr17:14,125,814...14,185,276
JBrowse link
G PRIMPOL primase and DNA directed polymerase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:45,764,261...45,851,052
Ensembl chr15:45,709,710...45,851,421
JBrowse link
G RAD51 RAD51 recombinase involved_in
acts_upstream_of_or_within
ISO (PMID:22778135)
(MGI:5442243|PMID:22778135)
(PMID:25585578)
BHF-UCL
MGI
UniProt
PMID:22778135 PMID:25585578 MGI:5442243 NCBI chr 1:130,592,414...130,640,326
Ensembl chr 1:130,586,647...130,640,136
JBrowse link
G RFWD3 ring finger and WD repeat domain 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:12,952,243...12,994,053
Ensembl chr 6:12,952,350...12,994,050
JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5522574|PMID:24115439) BHF-UCL PMID:24115439 MGI:5522574 NCBI chr17:62,611,844...62,636,628 JBrowse link
G SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:118,627,734...118,688,005
Ensembl chr15:118,629,238...118,687,940
JBrowse link
G THOC1 THO complex 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:106,039,262...106,088,125
Ensembl chr 6:106,040,042...106,088,026
JBrowse link
G TONSL tonsoku like, DNA repair protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:349,992...361,749
Ensembl chr 4:348,652...362,200
JBrowse link
G TRAIP TRAF interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:32,332,336...32,380,988
Ensembl chr13:32,332,339...32,379,766
JBrowse link
G WRN WRN RecQ like helicase involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:53,966,968...54,094,855
Ensembl chr15:53,966,972...54,094,587
JBrowse link
G ZRANB3 zinc finger RANBP2-type containing 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:16,414,291...16,727,659
Ensembl chr15:16,414,757...16,727,842
JBrowse link
DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MRE11 MRE11 homolog, double strand break repair nuclease involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,572,352...26,634,596
Ensembl chr 9:26,572,360...26,634,568
JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:40,117,348...40,171,935
Ensembl chr17:40,112,978...40,171,895
JBrowse link
mitotic recombination-dependent replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCA2 BRCA2 DNA repair associated involved_in ISO (PMID:21076401) BHF-UCL PMID:21076401 NCBI chr11:8,805,950...8,858,128 JBrowse link
G RAD51 RAD51 recombinase involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:130,592,414...130,640,326
Ensembl chr 1:130,586,647...130,640,136
JBrowse link
regulation of DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZNF365 zinc finger protein 365 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:65,861,398...65,888,341
Ensembl chr14:65,861,563...65,888,337
JBrowse link
replication fork reversal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNA2 DNA replication helicase/nuclease 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:71,550,405...71,607,067
Ensembl chr14:71,549,815...71,651,089
JBrowse link
G FANCM FA complementation group M involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:175,333,965...175,402,065
Ensembl chr 1:175,334,047...175,445,650
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16579
    metabolic process 10421
      cellular metabolic process 9468
        cellular macromolecule metabolic process 7274
          DNA metabolic process 814
            DNA-dependent DNA replication maintenance of fidelity 46
              replication fork processing 38
                DNA strand resection involved in replication fork processing + 3
                mitotic recombination-dependent replication fork processing + 2
                negative regulation of mitotic recombination involved in replication fork processing 0
                replication fork reversal 2
                stalled replication fork localization to nuclear periphery 0
Path 2
Term Annotations click to browse term
  biological_process 16579
    metabolic process 10421
      organic substance metabolic process 9986
        organic substance biosynthetic process 5191
          macromolecule biosynthetic process 4337
            cellular macromolecule biosynthetic process 4295
              DNA replication 236
                DNA-dependent DNA replication 140
                  DNA-dependent DNA replication maintenance of fidelity 46
                    replication fork processing 38
                      DNA strand resection involved in replication fork processing + 3
                      mitotic recombination-dependent replication fork processing + 2
                      negative regulation of mitotic recombination involved in replication fork processing 0
                      replication fork reversal 2
                      stalled replication fork localization to nuclear periphery 0
paths to the root