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ONTOLOGY REPORT - ANNOTATIONS


Term:replication fork processing
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Accession:GO:0031297 term browser browse the term
Definition:The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes.
Synonyms:exact_synonym: collapsed replication fork processing;   recovery from replication fork arrest;   recovery from replication fork stalling
 narrow_synonym: recovery from replication fork arrest at rDNA locus;   recovery from replication fork stalling at rDNA locus;   replication fork processing at rDNA locus;   replication fork processing at ribosomal DNA locus
 related_synonym: replication fork restart;   replication restart
 alt_id: GO:0034065


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replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALYREF Aly/REF export factor involved_in IMP (PMID:22144908) UniProt PMID:22144908 NCBI chr17:81,887,835...81,891,587
Ensembl chr17:81,887,835...81,891,586
JBrowse link
G ATR ATR serine/threonine kinase involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:142,449,235...142,578,793
Ensembl chr 3:142,449,007...142,578,733
JBrowse link
G ATRX ATRX chromatin remodeler involved_in ISS UniProt GO_REF:0000024 NCBI chr  X:77,504,880...77,786,235
Ensembl chr  X:77,504,880...77,786,233
JBrowse link
G BLM BLM RecQ like helicase involved_in IDA (PMID:17115688) UniProt PMID:17115688 NCBI chr15:90,717,346...90,816,166
Ensembl chr15:90,717,346...90,816,166
JBrowse link
G BOD1L1 biorientation of chromosomes in cell division 1 like 1 involved_in IDA (PMID:26166705) UniProt PMID:26166705 NCBI chr 4:13,568,738...13,627,725
Ensembl chr 4:13,568,738...13,627,725
JBrowse link
G CDK9 cyclin dependent kinase 9 involved_in IDA (PMID:20930849) UniProt PMID:20930849 NCBI chr 9:127,786,034...127,790,792
Ensembl chr 9:127,785,679...127,790,792
JBrowse link
G CENPS centromere protein S involved_in IMP
IBA
(PMID:20347428)
(PMID:21873635)
UniProt
GO_Central
PMID:20347428 PMID:21873635 NCBI chr 1:10,430,433...10,442,808
Ensembl chr 1:10,430,433...10,442,808
JBrowse link
G CENPS-CORT CENPS-CORT readthrough involved_in IBA
IMP
(PMID:21873635)
(PMID:20347428)
GO_Central
UniProt
PMID:20347428 PMID:21873635 NCBI chr 1:10,430,433...10,452,153
Ensembl chr 1:10,430,102...10,452,153
JBrowse link
G CENPX centromere protein X involved_in IBA
IMP
(PMID:21873635)
(PMID:20347428)
GO_Central
UniProt
PMID:20347428 PMID:21873635 NCBI chr17:82,018,703...82,022,930
Ensembl chr17:82,018,702...82,024,107
JBrowse link
G CORT cortistatin involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:10,450,031...10,451,998
Ensembl chr 1:10,450,031...10,451,998
JBrowse link
G DDX11 DEAD/H-box helicase 11 involved_in IMP (PMID:26503245) UniProt PMID:26503245 NCBI chr12:31,073,860...31,104,799
Ensembl chr12:31,073,860...31,104,799
JBrowse link
G EME1 essential meiotic structure-specific endonuclease 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:50,373,224...50,381,483
Ensembl chr17:50,373,220...50,381,483
JBrowse link
G EME2 essential meiotic structure-specific endonuclease subunit 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:1,772,810...1,781,702
Ensembl chr16:1,772,810...1,781,708
JBrowse link
G ETAA1 ETAA1 activator of ATR kinase involved_in IBA
IDA
(PMID:21873635)
(PMID:27723717), (PMID:27723720)
GO_Central
UniProt
PMID:21873635 PMID:27723717 PMID:27723720 NCBI chr 2:67,397,317...67,412,089
Ensembl chr 2:67,397,322...67,412,089
JBrowse link
G EXD2 exonuclease 3'-5' domain containing 2 involved_in IMP (PMID:31255466) UniProt PMID:31255466 NCBI chr14:69,191,498...69,244,018
Ensembl chr14:69,191,511...69,244,020
JBrowse link
G FAM111A FAM111 trypsin like peptidase A involved_in IDA (PMID:32165630) UniProt PMID:32165630 NCBI chr11:59,142,856...59,155,039
Ensembl chr11:59,142,748...59,155,039
JBrowse link
G FANCM FA complementation group M involved_in IMP (PMID:20347428) UniProt PMID:20347428 NCBI chr14:45,135,930...45,200,890
Ensembl chr14:45,135,930...45,200,890
JBrowse link
G FBH1 F-box DNA helicase 1 involved_in IBA
IDA
(PMID:21873635)
(PMID:25585578)
GO_Central
UniProt
PMID:21873635 PMID:25585578 NCBI chr10:5,889,572...5,937,593
Ensembl chr10:5,890,203...5,937,594
JBrowse link
G GEN1 GEN1 Holliday junction 5' flap endonuclease involved_in IDA (PMID:26578604) UniProt PMID:26578604 NCBI chr 2:17,753,687...17,788,946
Ensembl chr 2:17,753,858...17,788,946
JBrowse link
G KHDC3L KH domain containing 3 like, subcortical maternal complex member involved_in ISS UniProt GO_REF:0000024 NCBI chr 6:73,362,658...73,364,171
Ensembl chr 6:73,362,658...73,364,171
JBrowse link
G MMS22L MMS22 like, DNA repair protein involved_in IBA
IEA
IMP
(PMID:21873635)
(PMID:21055983), (PMID:21055984), (PMID:21055985)
GO_Central
InterPro
UniProt
PMID:21055983 PMID:21055984 PMID:21055985 PMID:21873635 GO_REF:0000002 NCBI chr 6:97,142,161...97,283,437
Ensembl chr 6:97,142,161...97,283,217
JBrowse link
G NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 involved_in IDA (PMID:26323318) ParkinsonsUK-UCL PMID:26323318 NCBI chr 1:205,712,822...205,750,220
Ensembl chr 1:205,712,822...205,750,182
JBrowse link
G OOEP oocyte expressed protein involved_in ISS UniProt GO_REF:0000024 NCBI chr 6:73,368,555...73,369,897
Ensembl chr 6:73,368,555...73,395,133
JBrowse link
G PCNA proliferating cell nuclear antigen involved_in ISS (PMID:24115439) BHF-UCL PMID:24115439 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PRIMPOL primase and DNA directed polymerase involved_in IBA
IMP
IDA
(PMID:21873635)
(PMID:24240614), (PMID:24267451)
(PMID:28534480)
GO_Central
UniProt
PMID:21873635 PMID:24240614 PMID:24267451 PMID:28534480 NCBI chr 4:184,649,672...184,694,952
Ensembl chr 4:184,649,667...184,694,963
JBrowse link
G RAD51 RAD51 recombinase involved_in
acts_upstream_of_or_within
IMP
ISO
IDA
(PMID:22778135)
(MGI:5442243|PMID:22778135)
(PMID:25585578)
BHF-UCL
MGI
UniProt
PMID:22778135 PMID:25585578 MGI:5442243 NCBI chr15:40,694,774...40,732,340
Ensembl chr15:40,694,774...40,732,340
JBrowse link
G RFWD3 ring finger and WD repeat domain 3 involved_in IDA (PMID:26474068) UniProt PMID:26474068 NCBI chr16:74,621,396...74,666,892
Ensembl chr16:74,621,399...74,666,877
JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 involved_in ISS (PMID:24115439) BHF-UCL PMID:24115439 NCBI chr20:63,657,810...63,696,253
Ensembl chr20:63,657,810...63,696,253
JBrowse link
G SETMAR SET domain and mariner transposase fusion gene involved_in IMP (PMID:20457750), (PMID:22231448), (PMID:24573677) UniProt PMID:20457750 PMID:22231448 PMID:24573677 NCBI chr 3:4,303,369...4,320,649
Ensembl chr 3:4,303,304...4,317,567
JBrowse link
G SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 involved_in IBA
IEA
TAS
IMP
(PMID:21873635)
(PMID:27918544)
(PMID:19793862)
GO_Central
InterPro
BHF-UCL
UniProt
PMID:19793862 PMID:21873635 PMID:27918544 GO_REF:0000002 NCBI chr 2:216,412,484...216,483,053
Ensembl chr 2:216,412,414...216,483,053
JBrowse link
G THOC1 THO complex 1 involved_in IMP (PMID:22144908) UniProt PMID:22144908 NCBI chr18:214,348...268,047
Ensembl chr18:214,520...268,050
JBrowse link
G TONSL tonsoku like, DNA repair protein involved_in IMP (PMID:21055983), (PMID:21055984), (PMID:21055985) UniProt PMID:21055983 PMID:21055984 PMID:21055985 NCBI chr 8:144,428,775...144,444,488
Ensembl chr 8:144,428,775...144,444,440
JBrowse link
G TRAIP TRAF interacting protein involved_in IDA
IMP
(PMID:26711499)
(PMID:27462463)
UniProt PMID:26711499 PMID:27462463 NCBI chr 3:49,828,595...49,856,584
Ensembl chr 3:49,828,601...49,856,574
JBrowse link
G WRN WRN RecQ like helicase involved_in IDA
IMP
(PMID:17115688)
(PMID:12882351)
UniProt PMID:12882351 PMID:17115688 NCBI chr 8:31,033,749...31,176,138
Ensembl chr 8:31,033,788...31,176,138
JBrowse link
G ZRANB3 zinc finger RANBP2-type containing 3 involved_in IDA
IBA
(PMID:22704558), (PMID:22705370)
(PMID:21873635)
UniProt
GO_Central
PMID:21873635 PMID:22704558 PMID:22705370 NCBI chr 2:135,196,969...135,531,218
Ensembl chr 2:135,136,916...135,531,218
JBrowse link
DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MRE11 MRE11 homolog, double strand break repair nuclease involved_in IDA (PMID:29670289) UniProt PMID:29670289 NCBI chr11:94,415,570...94,512,701
Ensembl chr11:94,415,570...94,493,885
JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in IDA (PMID:28834754), (PMID:29670289) UniProt PMID:28834754 PMID:29670289 NCBI chr20:36,889,773...36,951,708
Ensembl chr20:36,890,229...36,951,893
JBrowse link
mitotic recombination-dependent replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCA2 BRCA2 DNA repair associated involved_in IMP (PMID:21076401) BHF-UCL PMID:21076401 NCBI chr13:32,315,508...32,400,268
Ensembl chr13:32,315,086...32,400,268
JBrowse link
G RAD51 RAD51 recombinase involved_in IEA InterPro GO_REF:0000002 NCBI chr15:40,694,774...40,732,340
Ensembl chr15:40,694,774...40,732,340
JBrowse link
regulation of DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZNF365 zinc finger protein 365 involved_in IMP
IBA
(PMID:23966166)
(PMID:21873635)
UniProt
GO_Central
PMID:21873635 PMID:23966166 NCBI chr10:62,374,369...62,544,262
Ensembl chr10:62,374,192...62,480,288
JBrowse link
replication fork reversal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNA2 DNA replication helicase/nuclease 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:68,414,064...68,472,521
Ensembl chr10:68,414,064...68,472,121
JBrowse link
G FANCM FA complementation group M involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:45,135,930...45,200,890
Ensembl chr14:45,135,930...45,200,890
JBrowse link
G ZGRF1 zinc finger GRF-type containing 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:112,539,339...112,636,995
Ensembl chr 4:112,539,333...112,636,995
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18537
    metabolic process 11867
      cellular metabolic process 10809
        cellular macromolecule metabolic process 8265
          DNA metabolic process 964
            DNA-dependent DNA replication maintenance of fidelity 49
              replication fork processing 41
                DNA strand resection involved in replication fork processing + 3
                mitotic recombination-dependent replication fork processing + 2
                negative regulation of mitotic recombination involved in replication fork processing 0
                replication fork reversal 3
                stalled replication fork localization to nuclear periphery 0
Path 2
Term Annotations click to browse term
  biological_process 18537
    metabolic process 11867
      organic substance metabolic process 11374
        organic substance biosynthetic process 6083
          macromolecule biosynthetic process 5045
            cellular macromolecule biosynthetic process 4998
              DNA replication 284
                DNA-dependent DNA replication 163
                  DNA-dependent DNA replication maintenance of fidelity 49
                    replication fork processing 41
                      DNA strand resection involved in replication fork processing + 3
                      mitotic recombination-dependent replication fork processing + 2
                      negative regulation of mitotic recombination involved in replication fork processing 0
                      replication fork reversal 3
                      stalled replication fork localization to nuclear periphery 0
paths to the root