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ONTOLOGY REPORT - ANNOTATIONS


Term:replication fork processing
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Accession:GO:0031297 term browser browse the term
Definition:The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes.
Synonyms:exact_synonym: collapsed replication fork processing;   recovery from replication fork arrest;   recovery from replication fork stalling
 narrow_synonym: recovery from replication fork arrest at rDNA locus;   recovery from replication fork stalling at rDNA locus;   replication fork processing at rDNA locus;   replication fork processing at ribosomal DNA locus
 related_synonym: replication fork restart;   replication restart
 alt_id: GO:0034065


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replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALYREF Aly/REF export factor involved_in ISO (PMID:22144908) UniProt PMID:22144908 NCBI chr 9:398,207...402,787
Ensembl chr 9:399,072...402,721
JBrowse link
G ATR ATR serine/threonine kinase involved_in ISO (MGI:6467697|PMID:29125140) UniProt PMID:29125140 MGI:6467697 NCBI chr23:38,131,956...38,223,888
Ensembl chr23:38,132,788...38,224,016
JBrowse link
G ATRX ATRX chromatin remodeler involved_in ISO (MGI:5568153|PMID:24651726) UniProt PMID:24651726 MGI:5568153 NCBI chr  X:59,772,067...60,107,016
Ensembl chr  X:59,774,585...60,106,980
JBrowse link
G BLM BLM RecQ like helicase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:53,408,120...53,506,728
Ensembl chr 3:53,408,217...53,473,146
JBrowse link
G BOD1L1 biorientation of chromosomes in cell division 1 like 1 involved_in ISO (PMID:26166705) UniProt PMID:26166705 NCBI chr 3:66,465,813...66,520,414
Ensembl chr 3:66,474,570...66,519,777
JBrowse link
G CDK9 cyclin dependent kinase 9 involved_in ISO (PMID:20930849) UniProt PMID:20930849 NCBI chr 9:55,615,271...55,619,493
Ensembl chr 9:55,615,827...55,620,236
JBrowse link
G CENPX centromere protein X involved_in ISO (PMID:20347428) UniProt PMID:20347428
G DDX11 DEAD/H-box helicase 11 involved_in ISO (PMID:26503245) UniProt PMID:26503245 NCBI chr27:42,067,845...42,102,699
Ensembl chr27:42,067,898...42,105,870
JBrowse link
G ETAA1 ETAA1 activator of ATR kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:66,631,411...66,644,753
Ensembl chr10:66,631,544...66,643,728
JBrowse link
G EXD2 exonuclease 3'-5' domain containing 2 involved_in ISO (PMID:31255466) UniProt PMID:31255466 NCBI chr 8:43,028,537...43,082,038
Ensembl chr 8:43,042,563...43,187,969
JBrowse link
G FAM111A FAM111 trypsin like peptidase A involved_in ISO (PMID:32165630) UniProt PMID:32165630 NCBI chr18:37,584,326...37,595,316 JBrowse link
G FANCM FA complementation group M involved_in ISO (PMID:20347428) UniProt PMID:20347428 NCBI chr 8:22,561,862...22,625,077
Ensembl chr 8:22,562,147...22,623,994
JBrowse link
G FBH1 F-box DNA helicase 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:30,047,994...30,095,761
Ensembl chr 2:30,048,567...30,095,696
JBrowse link
G GEN1 GEN1 Holliday junction 5' flap endonuclease involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:13,201,540...13,233,028
Ensembl chr17:13,201,777...13,232,120
JBrowse link
G KHDC3L KH domain containing 3 like, subcortical maternal complex member involved_in ISO (MGI:6467697|PMID:29125140) UniProt PMID:29125140 MGI:6467697 NCBI chr12:35,434,123...35,435,679
Ensembl chr12:35,434,123...35,468,943
JBrowse link
G MMS22L MMS22 like, DNA repair protein involved_in ISO (PMID:21055983), (PMID:21055984), (PMID:21055985) UniProt PMID:21055983 PMID:21055984 PMID:21055985 NCBI chr12:55,584,884...55,713,996
Ensembl chr12:55,588,888...55,713,341
JBrowse link
G NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 involved_in ISO (PMID:26323318) ParkinsonsUK-UCL PMID:26323318 NCBI chr38:2,157,109...2,188,543
Ensembl chr38:2,160,233...2,170,560
JBrowse link
G OOEP oocyte expressed protein involved_in ISS UniProt GO_REF:0000024 NCBI chr12:35,431,562...35,449,540
Ensembl chr12:35,448,015...35,449,511
JBrowse link
G PCNA proliferating cell nuclear antigen involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:16,478,774...16,485,992
Ensembl chr24:16,478,769...16,484,992
JBrowse link
G PEX14 peroxisomal biogenesis factor 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:85,379,378...85,389,175 JBrowse link
G PRIMPOL primase and DNA directed polymerase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:45,861,244...45,920,183
Ensembl chr16:45,856,042...45,918,761
JBrowse link
G RAD51 RAD51 recombinase involved_in
acts_upstream_of_or_within
ISO (PMID:25585578)
(MGI:5442243|PMID:22778135)
(PMID:22778135)
UniProt
MGI
BHF-UCL
PMID:22778135 PMID:25585578 MGI:5442243 NCBI chr30:7,842,540...7,877,128
Ensembl chr30:7,842,540...7,877,606
JBrowse link
G RFWD3 ring finger and WD repeat domain 3 involved_in ISO (PMID:26474068) UniProt PMID:26474068 NCBI chr 5:75,960,909...76,001,088
Ensembl chr 5:75,960,955...76,000,467
JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5522574|PMID:24115439) BHF-UCL PMID:24115439 MGI:5522574 NCBI chr24:47,219,977...47,248,791 JBrowse link
G SETMAR SET domain without mariner transposase fusion involved_in ISO (PMID:20457750), (PMID:22231448), (PMID:24573677) UniProt PMID:20457750 PMID:22231448 PMID:24573677 NCBI chr20:13,214,241...13,224,020
Ensembl chr20:13,214,241...13,224,020
JBrowse link
G SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr37:23,364,941...23,425,206
Ensembl chr37:23,367,220...23,419,248
JBrowse link
G THOC1 THO complex 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:67,082,100...67,136,592
Ensembl chr 7:67,082,231...67,136,525
JBrowse link
G TONSL tonsoku like, DNA repair protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:37,846,010...37,857,633
Ensembl chr13:37,846,149...37,857,668
JBrowse link
G TRAIP TRAF interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:39,430,109...39,454,437
Ensembl chr20:39,430,489...39,453,933
JBrowse link
G WRN WRN RecQ like helicase involved_in ISO (PMID:12882351)
(PMID:17115688)
UniProt PMID:12882351 PMID:17115688 NCBI chr16:33,164,662...33,304,466
Ensembl chr16:33,167,364...33,304,625
JBrowse link
G ZRANB3 zinc finger RANBP2-type containing 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:38,003,273...38,302,598
Ensembl chr19:37,957,421...38,301,888
JBrowse link
DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MRE11 MRE11 homolog, double strand break repair nuclease involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:6,448,909...6,528,185
Ensembl chr21:6,449,822...6,527,119
JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:25,623,997...25,676,336
Ensembl chr24:25,626,134...25,680,902
JBrowse link
mitotic recombination-dependent replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCA2 BRCA2 DNA repair associated involved_in ISO (PMID:21076401) BHF-UCL PMID:21076401 NCBI chr25:7,734,450...7,797,851
Ensembl chr25:7,734,453...7,797,815
JBrowse link
G RAD51 RAD51 recombinase involved_in IEA InterPro GO_REF:0000002 NCBI chr30:7,842,540...7,877,128
Ensembl chr30:7,842,540...7,877,606
JBrowse link
regulation of DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZNF365 zinc finger protein 365 involved_in ISO (PMID:23966166) UniProt PMID:23966166 NCBI chr 4:14,297,652...14,429,634
Ensembl chr 4:14,311,302...14,331,568
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13863
    metabolic process 8968
      cellular metabolic process 8160
        cellular macromolecule metabolic process 6246
          DNA metabolic process 737
            DNA-dependent DNA replication maintenance of fidelity 40
              replication fork processing 35
                DNA strand resection involved in replication fork processing + 3
                mitotic recombination-dependent replication fork processing + 2
                negative regulation of mitotic recombination involved in replication fork processing 0
                replication fork reversal 0
                stalled replication fork localization to nuclear periphery 0
Path 2
Term Annotations click to browse term
  biological_process 13863
    metabolic process 8968
      organic substance metabolic process 8616
        organic substance biosynthetic process 4455
          macromolecule biosynthetic process 3696
            cellular macromolecule biosynthetic process 3657
              DNA replication 212
                DNA-dependent DNA replication 126
                  DNA-dependent DNA replication maintenance of fidelity 40
                    replication fork processing 35
                      DNA strand resection involved in replication fork processing + 3
                      mitotic recombination-dependent replication fork processing + 2
                      negative regulation of mitotic recombination involved in replication fork processing 0
                      replication fork reversal 0
                      stalled replication fork localization to nuclear periphery 0
paths to the root