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ONTOLOGY REPORT - ANNOTATIONS


Term:replication fork processing
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Accession:GO:0031297 term browser browse the term
Definition:The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes.
Synonyms:exact_synonym: collapsed replication fork processing;   recovery from replication fork arrest;   recovery from replication fork stalling
 narrow_synonym: recovery from replication fork arrest at rDNA locus;   recovery from replication fork stalling at rDNA locus;   replication fork processing at rDNA locus;   replication fork processing at ribosomal DNA locus
 related_synonym: replication fork restart;   replication restart
 alt_id: GO:0034065


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replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alyref Aly/REF export factor involved_in ISO (PMID:22144908) UniProt PMID:22144908 NCBI chrNW_004955506:1,278,230...1,282,064
Ensembl chrNW_004955506:1,278,471...1,281,772
JBrowse link
G Atr ATR serine/threonine kinase involved_in ISO (MGI:6467697|PMID:29125140) UniProt PMID:29125140 MGI:6467697 NCBI chrNW_004955508:3,337,036...3,440,313
Ensembl chrNW_004955508:3,337,432...3,440,257
JBrowse link
G Atrx ATRX chromatin remodeler involved_in ISO (MGI:5568153|PMID:24651726) UniProt PMID:24651726 MGI:5568153 NCBI chrNW_004955557:947,368...1,252,701
Ensembl chrNW_004955557:947,167...1,252,724
JBrowse link
G Blm BLM RecQ like helicase involved_in ISO (PMID:17115688)
(MGI:6467697|PMID:29125140)
UniProt PMID:17115688 PMID:29125140 MGI:6467697 NCBI chrNW_004955416:14,814,753...14,899,865
Ensembl chrNW_004955416:14,842,033...14,899,687
JBrowse link
G Bod1l1 biorientation of chromosomes in cell division 1 like 1 involved_in ISO (PMID:26166705) UniProt PMID:26166705 NCBI chrNW_004955480:10,143,053...10,189,194
Ensembl chrNW_004955480:10,142,739...10,189,322
JBrowse link
G Cdk9 cyclin dependent kinase 9 involved_in ISO (PMID:20930849) UniProt PMID:20930849 NCBI chrNW_004955419:874,959...883,160
Ensembl chrNW_004955419:873,289...883,160
JBrowse link
G Cenps centromere protein S involved_in ISO (PMID:20347428) UniProt PMID:20347428 NCBI chrNW_004955486:3,157,535...3,167,424
Ensembl chrNW_004955486:3,157,535...3,167,397
JBrowse link
G Cenpx centromere protein X involved_in ISO (PMID:20347428) UniProt PMID:20347428 NCBI chrNW_004955506:1,149,566...1,151,919
Ensembl chrNW_004955506:1,149,566...1,151,919
JBrowse link
G Ddx11 DEAD/H-box helicase 11 involved_in ISO (PMID:26503245) UniProt PMID:26503245 NCBI chrNW_004955524:1,932,988...1,957,231
Ensembl chrNW_004955524:1,932,729...1,957,231
JBrowse link
G Etaa1 ETAA1 activator of ATR kinase involved_in ISO (PMID:27723717), (PMID:27723720) UniProt PMID:27723717 PMID:27723720 NCBI chrNW_004955424:17,271,690...17,321,276
Ensembl chrNW_004955424:17,307,963...17,320,007
JBrowse link
G Exd2 exonuclease 3'-5' domain containing 2 involved_in ISO (PMID:31255466) UniProt PMID:31255466 NCBI chrNW_004955466:1,114,299...1,169,124
Ensembl chrNW_004955466:1,110,395...1,169,242
JBrowse link
G Fam111a FAM111 trypsin like peptidase A involved_in ISO (PMID:32165630) UniProt PMID:32165630 NCBI chrNW_004955511:3,722,483...3,736,001
Ensembl chrNW_004955511:3,731,116...3,740,140
JBrowse link
G Fancm FA complementation group M involved_in ISO (PMID:20347428) UniProt PMID:20347428 NCBI chrNW_004955409:16,751,658...16,809,352 JBrowse link
G Fbh1 F-box DNA helicase 1 involved_in ISO (PMID:25585578)
(MGI:5566975|PMID:24108124)
UniProt PMID:24108124 PMID:25585578 MGI:5566975 NCBI chrNW_004955421:22,535,777...22,579,965
Ensembl chrNW_004955421:22,535,777...22,579,965
JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease involved_in ISO (PMID:26578604) UniProt PMID:26578604 NCBI chrNW_004955469:552,850...590,792
Ensembl chrNW_004955469:552,677...592,137
JBrowse link
G LOC102020128 histone-lysine N-methyltransferase SETMAR involved_in ISO (PMID:20457750), (PMID:22231448), (PMID:24573677) UniProt PMID:20457750 PMID:22231448 PMID:24573677 NCBI chrNW_004955421:9,066,906...9,080,352 JBrowse link
G Mms22l MMS22 like, DNA repair protein involved_in ISO (PMID:21055983), (PMID:21055984), (PMID:21055985) UniProt PMID:21055983 PMID:21055984 PMID:21055985 NCBI chrNW_004955411:23,125,203...23,245,941
Ensembl chrNW_004955411:23,125,121...23,245,950
JBrowse link
G Nucks1 nuclear casein kinase and cyclin dependent kinase substrate 1 involved_in ISO (PMID:26323318) ParkinsonsUK-UCL PMID:26323318 NCBI chrNW_004955406:41,412,855...41,448,551
Ensembl chrNW_004955406:41,417,983...41,449,177
JBrowse link
G Pcna proliferating cell nuclear antigen involved_in ISO (MGI:5522574|PMID:24115439) BHF-UCL PMID:24115439 MGI:5522574 NCBI chrNW_004955415:15,744,601...15,748,910
Ensembl chrNW_004955415:15,744,601...15,749,673
JBrowse link
G Primpol primase and DNA directed polymerase involved_in ISO (PMID:28534480)
(PMID:24240614), (PMID:24267451)
UniProt PMID:24240614 PMID:24267451 PMID:28534480 NCBI chrNW_004955403:24,278,727...24,307,312
Ensembl chrNW_004955403:24,279,122...24,303,682
JBrowse link
G Rad51 RAD51 recombinase involved_in
acts_upstream_of_or_within
ISO (PMID:22778135)
(MGI:5442243|PMID:22778135)
(PMID:25585578)
BHF-UCL
MGI
UniProt
PMID:22778135 PMID:25585578 MGI:5442243 NCBI chrNW_004955416:7,566,715...7,590,628
Ensembl chrNW_004955416:7,566,686...7,590,628
JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO (PMID:26474068) UniProt PMID:26474068 NCBI chrNW_004955484:2,824,057...2,857,321
Ensembl chrNW_004955484:2,824,422...2,858,283
JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5522574|PMID:24115439) BHF-UCL PMID:24115439 MGI:5522574 NCBI chrNW_004955528:531,680...578,003 JBrowse link
G Smarcal1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 involved_in ISO (PMID:19793862) UniProt PMID:19793862 NCBI chrNW_004955453:16,724,286...16,784,129
Ensembl chrNW_004955453:16,719,931...16,784,709
JBrowse link
G Thoc1 THO complex 1 involved_in ISO (PMID:22144908) UniProt PMID:22144908 NCBI chrNW_004955402:9,675,211...9,708,045
Ensembl chrNW_004955402:9,675,204...9,708,045
JBrowse link
G Tonsl tonsoku like, DNA repair protein involved_in ISO (PMID:21055983), (PMID:21055984), (PMID:21055985) UniProt PMID:21055983 PMID:21055984 PMID:21055985 NCBI chrNW_004955454:3,054,727...3,067,785
Ensembl chrNW_004955454:3,054,400...3,068,028
JBrowse link
G Traip TRAF interacting protein involved_in ISO (PMID:26711499)
(PMID:27462463)
UniProt PMID:26711499 PMID:27462463 NCBI chrNW_004955532:1,725,608...1,746,690
Ensembl chrNW_004955532:1,726,061...1,746,591
JBrowse link
G Wrn WRN RecQ like helicase involved_in ISO (PMID:17115688)
(PMID:12882351)
UniProt PMID:12882351 PMID:17115688 NCBI chrNW_004955463:7,495,243...7,633,532
Ensembl chrNW_004955463:7,525,100...7,633,596
JBrowse link
G Zranb3 zinc finger RANBP2-type containing 3 involved_in ISO (PMID:22704558), (PMID:22705370) UniProt PMID:22704558 PMID:22705370 NCBI chrNW_004955440:2,683,041...2,907,859
Ensembl chrNW_004955440:2,680,787...2,888,345
JBrowse link
DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO (PMID:28834754), (PMID:29670289) UniProt PMID:28834754 PMID:29670289 NCBI chrNW_004955422:24,714,103...24,780,672
Ensembl chrNW_004955422:24,735,161...24,778,830
JBrowse link
mitotic recombination-dependent replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2 DNA repair associated involved_in ISO (PMID:21076401) BHF-UCL PMID:21076401 NCBI chrNW_004955431:13,449,287...13,526,878
Ensembl chrNW_004955431:13,449,543...13,527,432
JBrowse link
regulation of DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Znf365 zinc finger protein 365 involved_in ISO (PMID:23966166) UniProt PMID:23966166 NCBI chrNW_004955425:15,652,373...15,675,255
Ensembl chrNW_004955425:15,652,373...15,675,336
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11978
    metabolic process 7562
      cellular metabolic process 6947
        cellular macromolecule metabolic process 5370
          DNA metabolic process 662
            DNA-dependent DNA replication maintenance of fidelity 37
              replication fork processing 32
                DNA strand resection involved in replication fork processing + 2
                mitotic recombination-dependent replication fork processing + 1
                negative regulation of mitotic recombination involved in replication fork processing 0
                replication fork reversal 0
                stalled replication fork localization to nuclear periphery 0
Path 2
Term Annotations click to browse term
  biological_process 11978
    metabolic process 7562
      organic substance metabolic process 7291
        organic substance biosynthetic process 3826
          macromolecule biosynthetic process 3164
            cellular macromolecule biosynthetic process 3124
              DNA replication 189
                DNA-dependent DNA replication 107
                  DNA-dependent DNA replication maintenance of fidelity 37
                    replication fork processing 32
                      DNA strand resection involved in replication fork processing + 2
                      mitotic recombination-dependent replication fork processing + 1
                      negative regulation of mitotic recombination involved in replication fork processing 0
                      replication fork reversal 0
                      stalled replication fork localization to nuclear periphery 0
paths to the root