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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of cyclase activity
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Accession:GO:0031281 term browser browse the term
Definition:Any process that activates or increases the activity of a cyclase.
Synonyms:exact_synonym: up regulation of cyclase activity;   upregulation of cyclase activity
 narrow_synonym: activation of cyclase activity;   stimulation of cyclase activity



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positive regulation of cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAPK14 mitogen-activated protein kinase 14 involved_in IMP (PMID:22027397) CACAO PMID:22027397 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,752...36,122,511
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in IMP (PMID:22027397) CACAO PMID:22027397 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 involved_in IMP (PMID:22027397) CACAO PMID:22027397 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
activation of adenylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACR acrosin involved_in IDA (PMID:3880736) UniProt PMID:3880736 NCBI chr22:50,738,204...50,745,339
Ensembl chr22:50,738,196...50,745,339
JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 involved_in TAS (PMID:1730060) PINC PMID:1730060 NCBI chr18:904,411...912,172
Ensembl chr18:904,871...912,172
JBrowse link
G ADORA2B adenosine A2b receptor involved_in TAS (PMID:8022409) PINC PMID:8022409 NCBI chr17:15,850,362...15,975,746
Ensembl chr17:15,945,130...15,975,746
JBrowse link
G ADORA3 adenosine A3 receptor involved_in TAS (PMID:9380026) PINC PMID:9380026 NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633
JBrowse link
G AVPR2 arginine vasopressin receptor 2 involved_in TAS (PMID:9224808) PINC PMID:9224808 NCBI chr  X:153,902,625...153,907,166
Ensembl chr  X:153,902,531...153,907,166
JBrowse link
G CALCA calcitonin related polypeptide alpha involved_in
acts_upstream_of_or_within
IDA
ISO
(PMID:10822112), (PMID:16014619)
(PMID:8582325)
UniProt
MGI
PMID:8582325 PMID:10822112 PMID:16014619 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354
JBrowse link
G CAP1 cyclase associated actin cytoskeleton regulatory protein 1 involved_in TAS (PMID:7962207) PINC PMID:7962207 NCBI chr 1:40,040,240...40,072,648
Ensembl chr 1:40,040,233...40,072,649
JBrowse link
G CAP2 cyclase associated actin cytoskeleton regulatory protein 2 involved_in TAS (PMID:7962207) PINC PMID:7962207 NCBI chr 6:17,393,595...17,557,780
Ensembl chr 6:17,393,595...17,557,780
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 involved_in TAS (PMID:10598591) PINC PMID:10598591 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,277...45,835,828
JBrowse link
G DRD1 dopamine receptor D1 involved_in
acts_upstream_of_or_within
IDA
ISO
(PMID:2168520)
(PMID:12488442)
BHF-UCL
MGI
PMID:2168520 PMID:12488442 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
JBrowse link
G DRD5 dopamine receptor D5 involved_in TAS (PMID:9457173) BHF-UCL PMID:9457173 NCBI chr 4:9,781,634...9,784,009
Ensembl chr 4:9,781,634...9,784,009
JBrowse link
G EDNRA endothelin receptor type A involved_in TAS (PMID:8702836) PINC PMID:8702836 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954
JBrowse link
G GHRHR growth hormone releasing hormone receptor ISO RGD PMID:9845677 RGD:1601338 NCBI chr 7:30,963,953...30,979,528
Ensembl chr 7:30,938,669...30,993,254
JBrowse link
G GIPR gastric inhibitory polypeptide receptor involved_in TAS (PMID:7589426) PINC PMID:7589426 NCBI chr19:45,668,221...45,683,722
Ensembl chr19:45,668,221...45,683,722
JBrowse link
G GLP1R glucagon like peptide 1 receptor involved_in TAS (PMID:8405712) PINC PMID:8405712 NCBI chr 6:39,048,781...39,091,303
Ensembl chr 6:39,048,781...39,091,303
JBrowse link
G GNAL G protein subunit alpha L acts_upstream_of_or_within ISO (PMID:12488442) MGI PMID:12488442 NCBI chr18:11,689,264...11,885,685
Ensembl chr18:11,689,264...11,885,685
JBrowse link
G GNAS GNAS complex locus involved_in TAS (PMID:9159128) UniProt PMID:9159128 NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192
JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor involved_in ISO
ISS
RGD
BHF-UCL
PMID:8440169 GO_REF:0000024 RGD:2292602 NCBI chr 2:48,686,774...48,755,724
Ensembl chr 2:48,686,774...48,755,730
JBrowse link
G LINC02210-CRHR1 LINC02210-CRHR1 readthrough involved_in TAS (PMID:10598591) PINC PMID:10598591 NCBI chr17:45,620,346...45,835,828
Ensembl chr17:45,620,344...45,835,826
Ensembl chr17:45,620,344...45,835,826
JBrowse link
G P2RY11 purinergic receptor P2Y11 involved_in TAS (PMID:9405388) PINC PMID:9405388 NCBI chr19:10,111,693...10,115,372
Ensembl chr19:10,111,693...10,115,372
JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase involved_in IDA (PMID:15385642) BHF-UCL PMID:15385642 NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201
JBrowse link
G TMIGD3 transmembrane and immunoglobulin domain containing 3 involved_in TAS (PMID:9380026) PINC PMID:9380026 NCBI chr 1:111,483,348...111,563,962
Ensembl chr 1:111,483,348...111,563,962
JBrowse link
G VIPR2 vasoactive intestinal peptide receptor 2 ISO RGD PMID:8224221 RGD:70054 NCBI chr 7:159,028,175...159,144,867
Ensembl chr 7:159,028,175...159,144,867
JBrowse link
positive regulation of adenylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:21143600 RGD:8693686 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904
JBrowse link
G AKAP5 A-kinase anchoring protein 5 ISO RGD PMID:20410303 RGD:7242424 NCBI chr14:64,465,499...64,474,503
Ensembl chr14:64,465,499...64,474,503
JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in ISS UniProt GO_REF:0000024 NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950
JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:53,494,611...53,813,733
Ensembl chr 3:53,328,963...53,813,733
JBrowse link
G DRD5 dopamine receptor D5 involved_in NAS (PMID:7727453) UniProt PMID:7727453 NCBI chr 4:9,781,634...9,784,009
Ensembl chr 4:9,781,634...9,784,009
JBrowse link
G GCG glucagon ISO RGD PMID:2235678 RGD:11556254 (All species) (All species) NCBI chr 2:162,142,882...162,152,247
Ensembl chr 2:162,142,882...162,152,404
JBrowse link
G HPCA hippocalcin ISO RGD PMID:15336960 RGD:9686438 NCBI chr 1:32,885,996...32,894,646
Ensembl chr 1:32,885,994...32,898,441
JBrowse link
G NF1 neurofibromin 1 acts_upstream_of_or_within ISO (PMID:11788835) MGI PMID:11788835 NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116
JBrowse link
G ORAI1 ORAI calcium release-activated calcium modulator 1 involved_in IDA (PMID:19171672) UniProt PMID:19171672 NCBI chr12:121,626,530...121,643,109
Ensembl chr12:121,626,509...121,643,218
JBrowse link
G STIM1 stromal interaction molecule 1 involved_in IDA (PMID:19171672) UniProt PMID:19171672 NCBI chr11:3,854,604...4,093,210
Ensembl chr11:3,854,527...4,093,210
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 ISO RGD PMID:15901773 RGD:1598578 NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387
JBrowse link
positive regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor acts_upstream_of_or_within ISO (PMID:18340377) MGI PMID:18340377 NCBI chr17:15,850,362...15,975,746
Ensembl chr17:15,945,130...15,975,746
JBrowse link
G GUCA1A guanylate cyclase activator 1A involved_in ISO
ISS
RGD
UniProt
PMID:12545196 GO_REF:0000024 RGD:1599357 NCBI chr 6:42,173,364...42,180,056
Ensembl chr 6:42,173,364...42,181,338
JBrowse link
G GUCA1ANB-GUCA1A GUCA1ANB-GUCA1A readthrough involved_in ISS UniProt GO_REF:0000024 NCBI chr 6:42,155,406...42,180,056
Ensembl chr 6:42,155,406...42,180,056
JBrowse link
G NOS3 nitric oxide synthase 3 involved_in IMP
ISS
(PMID:17502619) BHF-UCL PMID:17502619 GO_REF:0000024 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link

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Term Annotations click to browse term
  biological_process 19688
    biological regulation 13544
      regulation of molecular function 1921
        regulation of catalytic activity 1295
          regulation of cyclase activity 59
            positive regulation of cyclase activity 39
              positive regulation of adenylate cyclase activity + 33
              positive regulation of guanylate cyclase activity 4
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