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ONTOLOGY REPORT - ANNOTATIONS


Term:Ndc80 complex
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Accession:GO:0031262 term browser browse the term
Definition:An outer kinetochore protein complex that is part of the KMN kinetochore network (also known as the NMS complex) providing the platform with which the plus ends of spindle microtubules directly interact to form stable kinetochore-microtubule attachments. A common subunit nomenclature is used from yeast to human: Ndc80, Nuf2, Spc24, and Spc25.
Synonyms:exact_synonym: Nuf2-Ndc80 complex


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Ndc80 complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ndc80 NDC80 kinetochore complex component ISO
IBA
(PMID:14699129)
PMID:21873635
RGD PMID:14699129, PMID:21873635 RGD:13792537 NCBI chr 9:119,837,857...119,871,435
Ensembl chr 9:119,839,016...119,871,382
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex ISO
IBA
ISS
(PMID:14699129)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:14699129, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr13:87,818,456...87,847,223
Ensembl chr13:87,818,391...87,847,263
JBrowse link
G Spc24 SPC24 component of NDC80 kinetochore complex ISO (PMID:14699129) RGD PMID:14699129 NCBI chr 8:22,780,639...22,785,908
Ensembl chr 8:22,780,725...22,785,671
JBrowse link
G Spc25 SPC25 component of NDC80 kinetochore complex ISO
IBA
ISS
(PMID:14699129)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:14699129, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 3:55,438,534...55,451,961
Ensembl chr 3:55,438,536...55,451,798
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6093
      Ndc80 complex 4
Path 2
Term Annotations click to browse term
  cellular_component 20609
    cellular anatomical entity 20358
      organelle 13258
        non-membrane-bounded organelle 5183
          intracellular non-membrane-bounded organelle 5172
            chromosome 1419
              chromosomal region 289
                chromosome, centromeric region 188
                  kinetochore 126
                    NMS complex 4
                      Ndc80 complex 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.