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ONTOLOGY REPORT - ANNOTATIONS


Term:SCAR complex
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Accession:GO:0031209 term browser browse the term
Definition:A pentameric complex that includes orthologues of human PIR121, Nap1, Abi, SCAR, and HSPC300 and regulates actin polymerization and/or depolymerization through small GTPase mediated signal transduction.
Synonyms:exact_synonym: WAVE complex;   WAVE regulatory complex
 broad_synonym: WRC


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SCAR complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi1 abl-interactor 1 part_of ISO
IEA
(PMID:21107423), (PMID:26428302)
GO_REF:0000107
(MGI:2664008|PMID:12672821), (MGI:6508508|PMID:26428302)
RGD
Ensembl
PMID:12672821 PMID:21107423 PMID:26428302 GO_REF:0000107 MGI:2664008 MGI:6508508 NCBI chr17:85,098,837...85,179,829
Ensembl chr17:85,098,550...85,179,792
JBrowse link
G Abi2 abl-interactor 2 part_of ISO (PMID:21107423) RGD PMID:21107423 NCBI chr 9:61,856,379...61,904,029
Ensembl chr 9:61,827,139...61,905,699
JBrowse link
G Abi3 ABI family, member 3 part_of ISO (PMID:17101133), (PMID:26428302)
(MGI:6508508|PMID:26428302)
RGD PMID:17101133 PMID:26428302 MGI:6508508 NCBI chr10:80,769,819...80,780,816
Ensembl chr10:80,769,822...80,780,816
JBrowse link
G Brk1 BRICK1 subunit of SCAR/WAVE actin nucleating complex part_of ISO
IBA
(PMID:18560548), (PMID:21107423)
PMID:21873635
RGD PMID:18560548 PMID:21107423 PMID:21873635 RGD:13792537 NCBI chr 4:146,750,821...146,766,050
Ensembl chr 4:146,750,821...146,768,856
JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 part_of ISO
IBA
(PMID:21107423)
PMID:21873635
RGD PMID:21107423 PMID:21873635 RGD:13792537 NCBI chr 1:106,710,924...106,799,393
Ensembl chr 1:106,711,016...106,799,386
JBrowse link
G Cyfip2 cytoplasmic FMR1 interacting protein 2 NOT|part_of IBA
ISO
PMID:21873635
(MGI:6508508|PMID:26428302)
(PMID:17101133), (PMID:26428302)
RGD PMID:17101133 PMID:26428302 PMID:21873635 MGI:6508508, RGD:13792537 NCBI chr10:30,621,318...30,741,113
Ensembl chr10:30,621,318...30,741,113
JBrowse link
G Nckap1 NCK-associated protein 1 part_of ISO
IEA
IBA
(PMID:21107423)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:21107423 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 3:65,417,450...65,491,769
Ensembl chr 3:65,417,453...65,492,217
JBrowse link
G Nckap1l NCK associated protein 1 like part_of IBA
ISO
ISS
PMID:21873635
(MGI:3818191|PMID:19015308)
GO_REF:0000024
(PMID:16417406)
RGD
UniProt
PMID:16417406 PMID:19015308 PMID:21873635 GO_REF:0000024 MGI:3818191, RGD:13792537 NCBI chr 7:134,577,443...134,622,934
Ensembl chr 7:134,577,482...134,622,934
JBrowse link
G RGD1561552 similar to WASP family 1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:73,040,984...73,043,716
Ensembl chr  X:73,040,902...73,043,716
JBrowse link
G Sra1 steroid receptor RNA activator 1 part_of ISO
IEA
(PMID:18560548)
GO_REF:0000107
RGD
Ensembl
PMID:18560548 GO_REF:0000107 NCBI chr18:28,269,192...28,273,023
Ensembl chr18:28,269,311...28,272,538
JBrowse link
G Wasf1 WASP family member 1 part_of ISO
IBA
(PMID:21107423)
PMID:21873635
RGD PMID:21107423 PMID:21873635 RGD:13792537 NCBI chr20:44,325,815...44,372,999
Ensembl chr20:44,325,795...44,372,996
JBrowse link
G Wasf2 WASP family member 2 part_of ISO
IBA
(PMID:17101133), (PMID:18560548), (PMID:21107423), (PMID:26428302)
PMID:21873635
(MGI:6508508|PMID:26428302)
RGD PMID:17101133 PMID:18560548 PMID:21107423 PMID:26428302 PMID:21873635 MGI:6508508, RGD:13792537 NCBI chr 5:145,336,816...145,402,041
Ensembl chr 5:145,336,842...145,399,242
JBrowse link
G Wasf3 WASP family member 3 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:8,563,805...8,660,799
Ensembl chr12:8,562,062...8,660,751
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20010
    protein-containing complex 6011
      SCAR complex 13
Path 2
Term Annotations click to browse term
  cellular_component 20010
    cellular anatomical entity 19714
      intracellular anatomical structure 14388
        cytoplasm 11359
          SCAR complex 13
paths to the root