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ONTOLOGY REPORT - ANNOTATIONS

Term:SCAR complex
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Accession:GO:0031209 term browser browse the term
Definition:A pentameric complex that includes orthologues of human PIR121, Nap1, Abi, SCAR, and HSPC300 and regulates actin polymerization and/or depolymerization through small GTPase mediated signal transduction.
Synonyms:exact_synonym: WAVE complex;   WAVE regulatory complex
 broad_synonym: WRC


show annotations for term's descendants           Sort by:
SCAR complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi1 abl-interactor 1 part_of ISO
IEA
IBA		 (PMID:21107423), (PMID:26428302)
GO_REF:0000107
GO_REF:0000033
(PMID:12672821), (PMID:26428302)		 RGD
Ensembl
GO_Central		 PMID:12672821 PMID:21107423 PMID:26428302 GO_REF:0000033 GO_REF:0000107 NCBI chr17:90,006,917...90,088,002
Ensembl chr17:85,098,550...85,179,792 		JBrowse link
G Abi2 abl-interactor 2 part_of ISO
IBA		 (PMID:21107423)
GO_REF:0000033		 RGD
GO_Central		 PMID:21107423 GO_REF:0000033 NCBI chr 9:69,321,072...69,490,630
Ensembl chr 9:61,827,139...61,905,699 		JBrowse link
G Abi3 ABI family, member 3 part_of ISO
IBA
IEA		 (PMID:17101133), (PMID:26428302)
GO_REF:0000033
(PMID:26428302)
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:17101133 PMID:26428302 GO_REF:0000033 GO_REF:0000107 NCBI chr10:81,266,571...81,277,561
Ensembl chr10:80,769,822...80,780,816 		JBrowse link
G Brk1 BRICK1 subunit of SCAR/WAVE actin nucleating complex part_of ISO
IBA
IEA		 (PMID:18560548), (PMID:21107423)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002		 RGD
GO_Central
Ensembl
InterPro		 PMID:18560548 PMID:21107423 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:148,306,436...148,321,668
Ensembl chr 4:146,750,821...146,768,856 		JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 part_of IBA
ISO		 GO_REF:0000033
(PMID:18560548), (PMID:21107423)		 GO_Central
RGD		 PMID:18560548 PMID:21107423 GO_REF:0000033 NCBI chr 1:115,842,754...115,935,163
Ensembl chr 1:106,711,016...106,799,386 		JBrowse link
G Cyfip2 cytoplasmic FMR1 interacting protein 2 part_of
NOT|part_of		 ISO
IBA		 (PMID:17101133), (PMID:26428302)
GO_REF:0000033
(PMID:26428302)		 RGD
GO_Central		 PMID:17101133 PMID:26428302 GO_REF:0000033 NCBI chr10:31,122,653...31,242,440
Ensembl chr10:30,621,318...30,741,113 		JBrowse link
G Nckap1 NCK-associated protein 1 part_of ISO
IEA
IBA		 (PMID:21107423)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:21107423 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:85,824,333...85,898,748
Ensembl chr 3:65,417,453...65,492,217 		JBrowse link
G Nckap1l NCK associated protein 1 like part_of ISO
ISS
IBA		 (PMID:16417406)
GO_REF:0000024
GO_REF:0000033
(PMID:19015308)		 RGD
UniProt
GO_Central		 PMID:16417406 PMID:19015308 GO_REF:0000024 GO_REF:0000033 NCBI chr 7:136,455,900...136,501,384
Ensembl chr 7:134,577,482...134,622,934 		JBrowse link
G Wasf1 WASP family member 1 part_of ISO
IEA
IBA		 (PMID:21107423)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:21107423 GO_REF:0000033 GO_REF:0000107 NCBI chr20:45,908,458...45,956,118
Ensembl chr20:44,325,795...44,372,996 		JBrowse link
G Wasf2 WASP family member 2 part_of ISO
IBA
IEA		 (PMID:17101133), (PMID:18560548), (PMID:21107423), (PMID:26428302)
GO_REF:0000033
(PMID:26428302)
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:17101133 PMID:18560548 PMID:21107423 PMID:26428302 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:150,620,733...150,685,943
Ensembl chr 5:145,336,842...145,399,242 		JBrowse link
G Wasf3 WASP family member 3 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:13,675,642...13,774,648
Ensembl chr12:8,562,062...8,660,751 		JBrowse link
G Wasfl WASP family member 1 like part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:73,040,984...73,043,716
Ensembl chr  X:73,040,902...73,043,716 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21364
    protein-containing complex 6830
      SCAR complex 12
Path 2
Term Annotations click to browse term
  cellular_component 21364
    cellular anatomical structure 21069
      intracellular anatomical structure 15590
        cytoplasm 12298
          SCAR complex 12
paths to the root