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ONTOLOGY REPORT - ANNOTATIONS


Term:SCAR complex
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Accession:GO:0031209 term browser browse the term
Definition:A pentameric complex that includes orthologues of human PIR121, Nap1, Abi, SCAR, and HSPC300 and regulates actin polymerization and/or depolymerization through small GTPase mediated signal transduction.
Synonyms:exact_synonym: WAVE complex;   WAVE regulatory complex
 broad_synonym: WRC


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SCAR complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi1 abl-interactor 1 IEA
ISO
GO_REF:0000107
(PMID:21107423)
Ensembl
RGD
PMID:21107423 GO_REF:0000107 NCBI chr17:89,951,662...90,033,334
Ensembl chr17:89,951,752...90,033,328
JBrowse link
G Abi2 abl-interactor 2 ISO (PMID:21107423) RGD PMID:21107423 NCBI chr 9:67,234,612...67,284,504
Ensembl chr 9:67,234,303...67,282,600
JBrowse link
G Brk1 BRICK1 subunit of SCAR/WAVE actin nucleating complex IBA
ISO
PMID:21873635
(PMID:18560548), (PMID:21107423)
RGD PMID:18560548, PMID:21107423, PMID:21873635 RGD:13792537 NCBI chr 4:145,559,206...145,574,438
Ensembl chr 4:145,559,206...145,574,438
JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 ISO
IBA
(PMID:21107423)
PMID:21873635
RGD PMID:21107423, PMID:21873635 RGD:13792537 NCBI chr 1:114,258,773...114,347,138
Ensembl chr 1:114,258,719...114,347,137
JBrowse link
G Cyfip2 cytoplasmic FMR1 interacting protein 2 NOT IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:31,278,746...31,419,235
Ensembl chr10:31,278,746...31,419,235
JBrowse link
G Nckap1 NCK-associated protein 1 IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:21107423)
Ensembl
RGD
PMID:21107423, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 3:67,725,180...67,804,680
Ensembl chr 3:67,725,947...67,787,990
JBrowse link
G Nckap1l NCK associated protein 1 like ISO
IBA
ISS
(PMID:16417406)
PMID:21873635
GO_REF:0000024
(MGI:MGI:3818191|PMID:19015308)
RGD
UniProt
PMID:16417406, PMID:19015308, PMID:21873635 GO_REF:0000024, MGI:MGI:3818191, RGD:13792537 NCBI chr 7:145,068,239...145,113,507
Ensembl chr 7:145,068,286...145,113,507
JBrowse link
G RGD1561552 similar to WASP family 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:79,064,200...79,066,932
Ensembl chr  X:79,064,204...79,066,932
JBrowse link
G Sra1 steroid receptor RNA activator 1 ISO
IEA
(PMID:18560548)
GO_REF:0000107
RGD
Ensembl
PMID:18560548 GO_REF:0000107 NCBI chr18:29,494,004...29,497,232
Ensembl chr18:29,494,014...29,497,410
JBrowse link
G Wasf1 WASP family member 1 ISO
IBA
(PMID:21107423)
PMID:21873635
RGD PMID:21107423, PMID:21873635 RGD:13792537 NCBI chr20:48,456,191...48,503,768
Ensembl chr20:48,455,705...48,503,898
JBrowse link
G Wasf2 WASP family member 2 ISO
IBA
(PMID:18560548), (PMID:21107423)
PMID:21873635
RGD PMID:18560548, PMID:21107423, PMID:21873635 RGD:13792537 NCBI chr 5:151,319,382...151,385,051
Ensembl chr 5:151,343,493...151,381,238
JBrowse link
G Wasf3 WASP family member 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:10,297,896...10,391,014
Ensembl chr12:10,298,555...10,391,270
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6093
      SCAR complex 12
Path 2
Term Annotations click to browse term
  cellular_component 20609
    cellular anatomical entity 20358
      intracellular anatomical structure 14706
        cytoplasm 11456
          SCAR complex 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.