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ONTOLOGY REPORT - ANNOTATIONS


Term:metallo-sulfur cluster assembly
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Accession:GO:0031163 term browser browse the term
Definition:The incorporation of a metal and exogenous sulfur into a metallo-sulfur cluster.
Synonyms:exact_synonym: metal-sulfur cluster assembly;   metallo-sulphur cluster assembly
 related_synonym: metallo-sulfur cluster biosynthesis



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[2Fe-2S] cluster assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BOLA2B bolA family member 2B involved_in ISO (PMID:27519415) UniProt PMID:27519415 NCBI chr 6:18,170,106...18,171,012 JBrowse link
G FDX2 ferredoxin 2 involved_in ISO (PMID:28001042) UniProt PMID:28001042 NCBI chr20:50,798,250...50,802,477 JBrowse link
G FXN frataxin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:88,288,566...88,311,228
Ensembl chr 1:88,288,566...88,311,228
JBrowse link
G GLRX3 glutaredoxin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:38,724,895...38,755,323
Ensembl chr28:38,724,941...38,755,316
JBrowse link
G GLRX5 glutaredoxin 5 involved_in ISO (PMID:23615440) UniProt PMID:23615440 NCBI chr 8:64,383,203...64,392,886
Ensembl chr 8:64,383,227...64,383,841
JBrowse link
G HSCB HscB mitochondrial iron-sulfur cluster cochaperone involved_in IBA
IEA
(PMID:21873635) GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr26:22,103,803...22,120,200
Ensembl chr26:22,103,845...22,120,198
JBrowse link
G ISCU iron-sulfur cluster assembly enzyme involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:18,300,800...18,307,668
Ensembl chr26:18,300,803...18,307,652
JBrowse link
G LYRM4 LYR motif containing 4 involved_in ISO (PMID:17331979), (PMID:31664822) UniProt PMID:17331979 PMID:31664822 NCBI chr35:5,229,851...5,373,965 JBrowse link
G NDUFAB1 NADH:ubiquinone oxidoreductase subunit AB1 involved_in ISO (PMID:31664822) UniProt PMID:31664822 NCBI chr 6:22,242,398...22,253,048 JBrowse link
G NFS1 NFS1 cysteine desulfurase involved_in IEA InterPro
Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chr24:24,593,348...24,614,938
Ensembl chr24:24,594,264...24,614,902
JBrowse link
[4Fe-4S] cluster assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FDX2 ferredoxin 2 acts_upstream_of ISO (PMID:28001042) UniProt PMID:28001042 NCBI chr20:50,798,250...50,802,477 JBrowse link
G FXN frataxin involved_in
acts_upstream_of
IEA
ISO
(PMID:29576242) Ensembl
UniProt
PMID:29576242 GO_REF:0000107 NCBI chr 1:88,288,566...88,311,228
Ensembl chr 1:88,288,566...88,311,228
JBrowse link
G ISCU iron-sulfur cluster assembly enzyme acts_upstream_of_positive_effect
involved_in
ISO
IEA
(PMID:29309586)
(PMID:16527810), (PMID:23940031), (PMID:29576242)
UniProt
Ensembl
PMID:16527810 PMID:23940031 PMID:29309586 PMID:29576242 GO_REF:0000107 NCBI chr26:18,300,800...18,307,668
Ensembl chr26:18,300,803...18,307,652
JBrowse link
G LYRM4 LYR motif containing 4 involved_in ISO (MGI:7327226|PMID:25597503) UniProt PMID:25597503 MGI:7327226 NCBI chr35:5,229,851...5,373,965 JBrowse link
G NFS1 NFS1 cysteine desulfurase acts_upstream_of
involved_in
ISO
IEA
(PMID:16527810) UniProt
Ensembl
PMID:16527810 GO_REF:0000107 NCBI chr24:24,593,348...24,614,938
Ensembl chr24:24,594,264...24,614,902
JBrowse link
iron incorporation into metallo-sulfur cluster term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FXN frataxin involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 1:88,288,566...88,311,228
Ensembl chr 1:88,288,566...88,311,228
JBrowse link
G NFS1 NFS1 cysteine desulfurase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr24:24,593,348...24,614,938
Ensembl chr24:24,594,264...24,614,902
JBrowse link
iron-sulfur cluster assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AAK1 AP2 associated kinase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr10:68,181,584...68,336,266
Ensembl chr10:68,134,902...68,335,988
JBrowse link
G ABCB7 ATP binding cassette subfamily B member 7 involved_in ISO (MGI:6695684|PMID:30765471) UniProt PMID:30765471 MGI:6695684 NCBI chr  X:58,305,804...58,470,827
Ensembl chr  X:58,306,776...58,471,417
JBrowse link
G BOLA2B bolA family member 2B involved_in ISO (PMID:27519415) ComplexPortal PMID:27519415 NCBI chr 6:18,170,106...18,171,012 JBrowse link
G CIAO1 cytosolic iron-sulfur assembly component 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
UniProt
InterPro
PMID:21873635 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr17:34,507,136...34,512,566
Ensembl chr17:34,508,662...34,512,486
JBrowse link
G CIAO2A cytosolic iron-sulfur assembly component 2A involved_in ISO (PMID:23891004) UniProt PMID:23891004 NCBI chr30:28,582,048...28,597,856
Ensembl chr30:28,582,902...28,597,748
JBrowse link
G CIAO2B cytosolic iron-sulfur assembly component 2B involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 5:82,384,719...82,386,655
Ensembl chr 5:82,384,756...82,386,540
JBrowse link
G CIAO3 cytosolic iron-sulfur assembly component 3 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:4946832|PMID:21367862)
GO_Central
MGI
PMID:21367862 PMID:21873635 MGI:4946832 NCBI chr 6:39,846,782...39,853,952
Ensembl chr 6:39,846,856...39,853,956
JBrowse link
G CIAPIN1 cytokine induced apoptosis inhibitor 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
InterPro
UniProt
InterPro
PMID:21873635 GO_REF:0000002 GO_REF:0000104 NCBI chr 2:58,977,592...58,992,785
Ensembl chr 2:58,977,676...58,992,581
JBrowse link
G FXN frataxin involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3611157|PMID:16278235)
(MGI:3770334|PMID:17597094)
InterPro
MGI
Ensembl
PMID:16278235 PMID:17597094 GO_REF:0000002 GO_REF:0000107 MGI:3611157 MGI:3770334 NCBI chr 1:88,288,566...88,311,228
Ensembl chr 1:88,288,566...88,311,228
JBrowse link
G GLRX3 glutaredoxin 3 involved_in ISO (PMID:27519415) ComplexPortal PMID:27519415 NCBI chr28:38,724,895...38,755,323
Ensembl chr28:38,724,941...38,755,316
JBrowse link
G HSCB HscB mitochondrial iron-sulfur cluster cochaperone involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:22,103,803...22,120,200
Ensembl chr26:22,103,845...22,120,198
JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr11:26,122,917...26,142,458
Ensembl chr11:26,121,499...26,142,434
JBrowse link
G IBA57 iron-sulfur cluster assembly factor IBA57 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:799,540...804,191
Ensembl chr14:800,294...801,811
JBrowse link
G ISCA1 iron-sulfur cluster assembly 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:73,468,850...73,527,123
Ensembl chr 1:73,487,403...73,525,830
JBrowse link
G ISCA2 iron-sulfur cluster assembly 2 involved_in IEA InterPro
InterPro
GO_REF:0000002 NCBI chr 8:47,650,864...47,657,896
Ensembl chr 8:47,650,938...47,652,292
JBrowse link
G ISCU iron-sulfur cluster assembly enzyme involved_in IEA UniProt
UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 NCBI chr26:18,300,800...18,307,668
Ensembl chr26:18,300,803...18,307,652
JBrowse link
G LYRM4 LYR motif containing 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr35:5,229,851...5,373,965 JBrowse link
G LYRM4 LYR motif containing 4 involved_in IEA InterPro GO_REF:0000002
G MMS19 MMS19 homolog, cytosolic iron-sulfur assembly component involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
UniProt
PMID:21873635 GO_REF:0000104 NCBI chr28:10,749,327...10,783,846
Ensembl chr28:10,749,325...10,783,805
JBrowse link
G NDOR1 NADPH dependent diflavin oxidoreductase 1 involved_in IEA UniProt
UniProt
GO_REF:0000104 NCBI chr 9:48,456,256...48,464,930
Ensembl chr 9:48,455,260...48,464,970
JBrowse link
G NFS1 NFS1 cysteine desulfurase involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000117 NCBI chr24:24,593,348...24,614,938
Ensembl chr24:24,594,264...24,614,902
JBrowse link
G NFU1 NFU1 iron-sulfur cluster scaffold involved_in IEA InterPro
InterPro
GO_REF:0000002 NCBI chr10:68,134,865...68,161,841
Ensembl chr10:68,134,902...68,335,988
JBrowse link
G NUBP1 NUBP iron-sulfur cluster assembly factor 1, cytosolic involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
UniProt
InterPro
UniProt
PMID:21873635 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr 6:31,900,540...31,922,087
Ensembl chr 6:31,896,596...31,921,989
JBrowse link
G NUBP2 NUBP iron-sulfur cluster assembly factor 2, cytosolic involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
InterPro
PMID:21873635 GO_REF:0000002 GO_REF:0000104 NCBI chr 6:39,119,332...39,121,869
Ensembl chr 6:39,119,337...39,122,370
JBrowse link
G NUBPL NUBP iron-sulfur cluster assembly factor, mitochondrial involved_in IEA
IBA
(PMID:21873635) InterPro
InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr 8:10,796,462...11,026,804
Ensembl chr 8:10,796,459...11,090,920
JBrowse link
G XDH xanthine dehydrogenase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3770334|PMID:17597094) Ensembl
Ensembl
MGI
PMID:17597094 GO_REF:0000107 MGI:3770334 NCBI chr17:24,900,708...24,960,748
Ensembl chr17:24,901,447...24,971,935
JBrowse link
positive regulation of iron-sulfur cluster assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB7 ATP binding cassette subfamily B member 7 involved_in ISO (PMID:17192393)
(MGI:3619656|PMID:16467350)
UniProt PMID:16467350 PMID:17192393 MGI:3619656 NCBI chr  X:58,305,804...58,470,827
Ensembl chr  X:58,306,776...58,471,417
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17341
    cellular process 16317
      cellular component organization or biogenesis 6441
        cellular component biogenesis 3223
          cellular component assembly 2966
            metallo-sulfur cluster assembly 29
              iron-sulfur cluster assembly + 29
              metal incorporation into metallo-sulfur cluster + 2
              sulfur incorporation into metallo-sulfur cluster 0
paths to the root