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ONTOLOGY REPORT - ANNOTATIONS


Term:metallo-sulfur cluster assembly
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Accession:GO:0031163 term browser browse the term
Definition:The incorporation of a metal and exogenous sulfur into a metallo-sulfur cluster.
Synonyms:exact_synonym: metal-sulfur cluster assembly;   metallo-sulphur cluster assembly
 related_synonym: metallo-sulfur cluster biosynthesis



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[2Fe-2S] cluster assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BOLA2B bolA family member 2B involved_in ISO (PMID:27519415) UniProt PMID:27519415
G FDX2 ferredoxin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:9,860,316...9,866,442
Ensembl chr19:10,526,287...10,532,152
JBrowse link
G FXN frataxin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:55,690,483...55,754,755
Ensembl chr 9:67,800,579...67,866,031
JBrowse link
G GLRX3 glutaredoxin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:126,730,314...126,775,918
Ensembl chr10:130,973,022...131,019,742
JBrowse link
G GLRX5 glutaredoxin 5 involved_in ISO (PMID:23615440) UniProt PMID:23615440 NCBI chr14:76,162,541...76,172,291 JBrowse link
G HSCB HscB mitochondrial iron-sulfur cluster cochaperone involved_in IEA InterPro GO_REF:0000002 NCBI chr22:9,811,294...9,826,245
Ensembl chr22:27,512,564...27,527,914
JBrowse link
G ISCU iron-sulfur cluster assembly enzyme involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:106,132,987...106,140,879
Ensembl chr12:109,529,162...109,537,053
JBrowse link
G LOC100989931 acyl carrier protein, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:170,136,429...170,137,102
Ensembl chr16:23,833,485...23,849,085
JBrowse link
G LYRM4 LYR motif containing 4 involved_in ISO (PMID:17331979), (PMID:31664822) UniProt PMID:17331979 PMID:31664822 NCBI chr 6:4,887,010...5,096,384
Ensembl chr 6:5,127,918...5,279,038
JBrowse link
G NDUFAB1 NADH:ubiquinone oxidoreductase subunit AB1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:14,513,734...14,529,087
Ensembl chr16:23,833,485...23,849,085
JBrowse link
G NFS1 NFS1 cysteine desulfurase involved_in IEA InterPro GO_REF:0000002 NCBI chr20:31,994,509...32,026,776 JBrowse link
[4Fe-4S] cluster assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FDX2 ferredoxin 2 involved_in
acts_upstream_of
IEA
ISO
(PMID:28001042) Ensembl
UniProt
PMID:28001042 GO_REF:0000107 NCBI chr19:9,860,316...9,866,442
Ensembl chr19:10,526,287...10,532,152
JBrowse link
G FXN frataxin involved_in
acts_upstream_of
IEA
ISO
(PMID:29576242) Ensembl
UniProt
PMID:29576242 GO_REF:0000107 NCBI chr 9:55,690,483...55,754,755
Ensembl chr 9:67,800,579...67,866,031
JBrowse link
G ISCU iron-sulfur cluster assembly enzyme acts_upstream_of_positive_effect
involved_in
ISO
IEA
(PMID:29309586)
(PMID:16527810), (PMID:23940031), (PMID:29576242)
UniProt
Ensembl
PMID:16527810 PMID:23940031 PMID:29309586 PMID:29576242 GO_REF:0000107 NCBI chr12:106,132,987...106,140,879
Ensembl chr12:109,529,162...109,537,053
JBrowse link
G LYRM4 LYR motif containing 4 involved_in ISO (MGI:7327226|PMID:25597503) UniProt PMID:25597503 MGI:7327226 NCBI chr 6:4,887,010...5,096,384
Ensembl chr 6:5,127,918...5,279,038
JBrowse link
G NFS1 NFS1 cysteine desulfurase involved_in
acts_upstream_of
IEA
ISO
(PMID:16527810) Ensembl
UniProt
PMID:16527810 GO_REF:0000107 NCBI chr20:31,994,509...32,026,776 JBrowse link
iron incorporation into metallo-sulfur cluster term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FXN frataxin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:55,690,483...55,754,755
Ensembl chr 9:67,800,579...67,866,031
JBrowse link
G NFS1 NFS1 cysteine desulfurase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:31,994,509...32,026,776 JBrowse link
iron-sulfur cluster assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB7 ATP binding cassette subfamily B member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:64,304,101...64,407,310
Ensembl chr  X:74,418,754...74,521,726
JBrowse link
G BOLA2B bolA family member 2B involved_in ISO (PMID:27519415) ComplexPortal PMID:27519415
G CIAO1 cytosolic iron-sulfur assembly component 1 involved_in IEA Ensembl
InterPro
UniProt
GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr2A:103,041,509...103,049,469
Ensembl chr2A:97,188,949...97,194,576
JBrowse link
G CIAO2A cytosolic iron-sulfur assembly component 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:43,025,577...43,047,013
Ensembl chr15:61,317,188...61,338,337
JBrowse link
G CIAO2B cytosolic iron-sulfur assembly component 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:47,247,278...47,249,617
Ensembl chr16:66,349,377...66,351,733
JBrowse link
G CIAO3 cytosolic iron-sulfur assembly component 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4946832|PMID:21367862) MGI
Ensembl
PMID:21367862 GO_REF:0000107 MGI:4946832 Ensembl chr16:742,818...754,087 JBrowse link
G CIAPIN1 cytokine induced apoptosis inhibitor 1 involved_in IEA UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 NCBI chr16:37,701,773...37,723,556
Ensembl chr16:56,835,024...56,856,502
JBrowse link
G FXN frataxin involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3770334|PMID:17597094)
(MGI:3611157|PMID:16278235)
InterPro
MGI
Ensembl
PMID:16278235 PMID:17597094 GO_REF:0000002 GO_REF:0000107 MGI:3611157 MGI:3770334 NCBI chr 9:55,690,483...55,754,755
Ensembl chr 9:67,800,579...67,866,031
JBrowse link
G GLRX3 glutaredoxin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:126,730,314...126,775,918
Ensembl chr10:130,973,022...131,019,742
JBrowse link
G HSCB HscB mitochondrial iron-sulfur cluster cochaperone involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:9,811,294...9,826,245
Ensembl chr22:27,512,564...27,527,914
JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:133,934,859...133,955,048
Ensembl chr 5:140,064,207...140,084,551
JBrowse link
G ISCA1 iron-sulfur cluster assembly 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:57,410,328...57,428,477
Ensembl chr 9:85,467,145...85,485,107
JBrowse link
G ISCA2 iron-sulfur cluster assembly 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr14:55,046,821...55,048,602
Ensembl chr14:73,894,694...73,896,444
JBrowse link
G ISCU iron-sulfur cluster assembly enzyme involved_in IEA InterPro
UniProt
GO_REF:0000002 GO_REF:0000104 NCBI chr12:106,132,987...106,140,879
Ensembl chr12:109,529,162...109,537,053
JBrowse link
G LOC117977511 iron-sulfur cluster assembly 2 homolog, mitochondrial-like involved_in IEA InterPro GO_REF:0000002 NCBI chr22:7,705,330...7,706,892 JBrowse link
G LYRM4 LYR motif containing 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr 6:4,887,010...5,096,384
Ensembl chr 6:5,127,918...5,279,038
JBrowse link
G MMS19 MMS19 homolog, cytosolic iron-sulfur assembly component involved_in IEA UniProt
Ensembl
GO_REF:0000104 GO_REF:0000107 NCBI chr10:94,080,690...94,120,811
Ensembl chr10:97,574,257...97,614,146
JBrowse link
G NDOR1 NADPH dependent diflavin oxidoreductase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr 9:108,265,305...108,278,923
Ensembl chr 9:137,233,940...137,247,716
JBrowse link
G NFS1 NFS1 cysteine desulfurase involved_in IEA UniProt GO_REF:0000117 NCBI chr20:31,994,509...32,026,776 JBrowse link
G NFU1 NFU1 iron-sulfur cluster scaffold involved_in IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chr2A:69,438,979...69,480,470
Ensembl chr2A:70,559,872...70,600,301
JBrowse link
G NUBP1 NUBP iron-sulfur cluster assembly factor 1, cytosolic involved_in IEA InterPro
Ensembl
UniProt
GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr16:9,681,800...9,708,673
Ensembl chr16:10,906,719...10,931,800
JBrowse link
G NUBP2 NUBP iron-sulfur cluster assembly factor 2, cytosolic involved_in IEA InterPro GO_REF:0000002 NCBI chr16:405,264...411,626 JBrowse link
G XDH xanthine dehydrogenase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3770334|PMID:17597094) MGI
Ensembl
PMID:17597094 GO_REF:0000107 MGI:3770334 NCBI chr2A:31,356,011...31,435,111
Ensembl chr2A:31,425,183...31,504,455
JBrowse link
positive regulation of iron-sulfur cluster assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB7 ATP binding cassette subfamily B member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:64,304,101...64,407,310
Ensembl chr  X:74,418,754...74,521,726
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15421
    cellular process 14244
      cellular component organization or biogenesis 5701
        cellular component biogenesis 2825
          cellular component assembly 2630
            metallo-sulfur cluster assembly 27
              iron-sulfur cluster assembly + 27
              metal incorporation into metallo-sulfur cluster + 2
              sulfur incorporation into metallo-sulfur cluster 0
paths to the root