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ONTOLOGY REPORT - ANNOTATIONS

Term:mRNA 3'-end processing
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Accession:GO:0031124 term browser browse the term
Definition:Any process involved in forming the mature 3' end of an mRNA molecule.
Synonyms:xref: Reactome:R-HSA-72187 "mRNA 3'-end processing";   Reactome:R-HSA-75067 "Processing of Capped Intronless Pre-mRNA"


show annotations for term's descendants           Sort by:
mRNA 3'-end processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc73 cell division cycle 73 involved_in ISS
ISO 		GO_REF:0000024
(PMID:21329879) 		UniProt
RGD		 PMID:21329879 GO_REF:0000024 NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656 		JBrowse link
G Clp1 cleavage factor polyribonucleotide kinase subunit 1 involved_in IEA GO_REF:0000104
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr 3:69,806,774...69,818,633
Ensembl chr 3:69,806,778...69,810,421 		JBrowse link
G Cpsf3 cleavage and polyadenylation specific factor 3 involved_in ISO
IEA 		(PMID:30507380)
GO_REF:0000107 		RGD
Ensembl		 PMID:30507380 GO_REF:0000107 NCBI chr 6:40,836,121...40,864,129
Ensembl chr 6:40,836,097...40,864,128 		JBrowse link
G Cpsf4 cleavage and polyadenylation specific factor 4 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr12:9,429,765...9,445,586
Ensembl chr12:9,429,523...9,445,586 		JBrowse link
G Cpsf4-ps1 cleavage and polyadenylation specific factor 4, pseudogene 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr  X:15,862,098...15,862,850
Ensembl chr  X:15,861,367...15,863,381 		JBrowse link
G Cpsf4l cleavage and polyadenylation specific factor 4-like involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr10:98,741,816...98,756,069
Ensembl chr10:98,743,649...98,751,590 		JBrowse link
G Cpsf4l2 cleavage and polyadenylation specific factor 4 like 2 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr12:10,211,744...10,213,512
Ensembl chr12:10,211,798...10,212,670 		JBrowse link
G Cpsf6 cleavage and polyadenylation specific factor 6 involved_in ISO
IEA 		(PMID:20695905)
GO_REF:0000107 		RGD
Ensembl		 PMID:20695905 GO_REF:0000107 NCBI chr 7:52,956,589...53,001,783
Ensembl chr 7:52,956,589...52,988,122 		JBrowse link
G Cpsf7 cleavage and polyadenylation specific factor 7 involved_in ISO
IEA 		(PMID:20695905)
GO_REF:0000107 		RGD
Ensembl		 PMID:20695905 GO_REF:0000107 NCBI chr 1:207,167,690...207,191,938
Ensembl chr 1:207,167,859...207,191,905 		JBrowse link
G Cstf1 cleavage stimulation factor subunit 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:161,144,522...161,156,294
Ensembl chr 3:161,144,548...161,156,300 		JBrowse link
G Cstf2 cleavage stimulation factor subunit 2 involved_in ISO
IEA 		(PMID:32816001)
GO_REF:0000107
GO_REF:0000002 		RGD
Ensembl
InterPro		 PMID:32816001 GO_REF:0000002 GO_REF:0000107 NCBI chr  X:97,253,559...97,279,476
Ensembl chr  X:97,253,586...97,279,476 		JBrowse link
G Cstf2t cleavage stimulation factor subunit 2, tau variant involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:228,952,617...228,956,183
Ensembl chr 1:228,952,504...228,955,873 		JBrowse link
G Cstf3 cleavage stimulation factor subunit 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:90,966,415...91,037,669
Ensembl chr 3:90,966,354...91,042,196 		JBrowse link
G Leo1 LEO1 homolog, Paf1/RNA polymerase II complex component involved_in ISS
ISO 		GO_REF:0000024
(PMID:21329879) 		UniProt
RGD		 PMID:21329879 GO_REF:0000024 NCBI chr 8:76,199,547...76,223,983
Ensembl chr 8:76,199,099...76,223,983 		JBrowse link
G Mblac1 metallo-beta-lactamase domain containing 1 involved_in ISO
IEA 		(PMID:30507380)
GO_REF:0000107 		RGD
Ensembl		 PMID:30507380 GO_REF:0000107 NCBI chr12:17,071,465...17,072,736
Ensembl chr12:17,071,465...17,072,735 		JBrowse link
G Nudt21 nudix hydrolase 21 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000002
(PMID:15937220), (PMID:20695905) 		UniProt
InterPro
RGD		 PMID:15937220 PMID:20695905 GO_REF:0000002 GO_REF:0000024 NCBI chr19:10,974,800...10,993,841
Ensembl chr19:10,974,241...10,991,682 		JBrowse link
G Paf1 PAF1 homolog, Paf1/RNA polymerase II complex component involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:21329879) 		UniProt
Ensembl
RGD		 PMID:21329879 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:83,683,654...83,689,233
Ensembl chr 1:83,668,813...83,689,237 		JBrowse link
G Papola poly (A) polymerase alpha involved_in ISO
IEA 		(PMID:7590244)
GO_REF:0000107 		RGD
Ensembl		 PMID:7590244 GO_REF:0000107 NCBI chr 6:124,682,015...124,734,706
Ensembl chr 6:124,682,105...124,734,468 		JBrowse link
G Pcf11 PCF11 cleavage and polyadenylation factor subunit involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:146,694,045...146,724,030
Ensembl chr 1:146,697,646...146,724,124 		JBrowse link
G Rprd1a regulation of nuclear pre-mRNA domain containing 1A involved_in IBA
IEA 		GO_REF:0000033
GO_REF:0000104 		GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000104 NCBI chr18:15,791,418...15,839,338
Ensembl chr18:15,791,418...15,839,338 		JBrowse link
G Rprd1b regulation of nuclear pre-mRNA domain containing 1B involved_in IBA
IEA 		GO_REF:0000033
GO_REF:0000104 		GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000104 NCBI chr 3:146,682,975...146,729,251
Ensembl chr 3:146,682,922...146,786,452 		JBrowse link
G Rprd2 regulation of nuclear pre-mRNA domain containing 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:183,311,132...183,367,959
Ensembl chr 2:183,293,114...183,367,407 		JBrowse link
G Tent2 terminal nucleotidyltransferase 2 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:15070731) 		UniProt
Ensembl
RGD		 PMID:15070731 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:24,380,135...24,432,099
Ensembl chr 2:24,380,225...24,432,099 		JBrowse link
G Tent4b terminal nucleotidyltransferase 4B involved_in ISO (PMID:28383716) RGD PMID:28383716 NCBI chr19:18,807,616...18,868,969
Ensembl chr19:18,807,525...18,869,537 		JBrowse link
G Tut1 terminal uridylyl transferase 1, U6 snRNA-specific involved_in ISO
IEA 		(PMID:18288197)
GO_REF:0000107 		RGD
Ensembl		 PMID:18288197 GO_REF:0000107 NCBI chr 1:205,848,691...205,859,767
Ensembl chr 1:205,848,772...205,859,764 		JBrowse link
G Wdr33 WD repeat domain 33 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:23,432,233...23,535,460
Ensembl chr18:23,432,191...23,468,597 		JBrowse link
G Zc3h3 zinc finger CCCH type containing 3 acts_upstream_of_or_within ISO
IEA 		(PMID:16115198)
GO_REF:0000107 		RGD
Ensembl		 PMID:16115198 GO_REF:0000107 NCBI chr 7:107,440,694...107,525,451
Ensembl chr 7:107,440,694...107,525,451 		JBrowse link
G Zcchc8 zinc finger CCHC-type containing 8 involved_in ISO
IEA 		(PMID:31488579)
GO_REF:0000107 		RGD
Ensembl		 PMID:31488579 GO_REF:0000107 NCBI chr12:32,869,170...32,892,707
Ensembl chr12:32,869,310...32,891,325 		JBrowse link
co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpsf3 cleavage and polyadenylation specific factor 3 involved_in ISO
IEA 		(PMID:8929409)
GO_REF:0000107 		RGD
Ensembl		 PMID:8929409 GO_REF:0000107 NCBI chr 6:40,836,121...40,864,129
Ensembl chr 6:40,836,097...40,864,128 		JBrowse link
G Cpsf6 cleavage and polyadenylation specific factor 6 involved_in ISO
IEA 		(PMID:29276085)
GO_REF:0000107 		RGD
Ensembl		 PMID:29276085 GO_REF:0000107 NCBI chr 7:52,956,589...53,001,783
Ensembl chr 7:52,956,589...52,988,122 		JBrowse link
G Cpsf7 cleavage and polyadenylation specific factor 7 involved_in ISO
ISS
IEA 		(PMID:29276085)
GO_REF:0000024
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:29276085 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:207,167,690...207,191,938
Ensembl chr 1:207,167,859...207,191,905 		JBrowse link
G Cstf3 cleavage stimulation factor subunit 3 involved_in ISO
IEA 		(PMID:7984242)
GO_REF:0000107 		RGD
Ensembl		 PMID:7984242 GO_REF:0000107 NCBI chr 3:90,966,415...91,037,669
Ensembl chr 3:90,966,354...91,042,196 		JBrowse link
G Nudt21 nudix hydrolase 21 involved_in ISO
ISS 		(PMID:29276085)
GO_REF:0000024 		RGD
UniProt		 PMID:29276085 GO_REF:0000024 NCBI chr19:10,974,800...10,993,841
Ensembl chr19:10,974,241...10,991,682 		JBrowse link
G Papola poly (A) polymerase alpha involved_in ISO
IEA 		(PMID:19224921)
GO_REF:0000107 		RGD
Ensembl		 PMID:19224921 GO_REF:0000107 NCBI chr 6:124,682,015...124,734,706
Ensembl chr 6:124,682,105...124,734,468 		JBrowse link
G Ssu72 SSU72 homolog, RNA polymerase II CTD phosphatase involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:20861839)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:20861839 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:166,312,267...166,343,432
Ensembl chr 5:166,313,650...166,343,429 		JBrowse link
G Tut1 terminal uridylyl transferase 1, U6 snRNA-specific involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:21102410)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:21102410 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:205,848,691...205,859,767
Ensembl chr 1:205,848,772...205,859,764 		JBrowse link
mitochondrial mRNA 3'-end processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angel2 angel homolog 2 involved_in ISO
IEA 		(PMID:36180430)
GO_REF:0000107 		RGD
Ensembl		 PMID:36180430 GO_REF:0000107 NCBI chr13:102,509,111...102,529,501
Ensembl chr13:102,510,589...102,529,493 		JBrowse link
mRNA 3'-end processing by stem-loop binding and cleavage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpsf2 cleavage and polyadenylation specific factor 2 involved_in ISO
IEA
IBA 		(PMID:18688255)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000033 		RGD
Ensembl
InterPro
GO_Central		 PMID:18688255 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:121,123,941...121,152,756
Ensembl chr 6:121,120,569...121,151,921 		JBrowse link
G Cpsf3 cleavage and polyadenylation specific factor 3 involved_in ISO
IEA
IBA 		(PMID:18688255)
GO_REF:0000107
(PMID:18955505)
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:18688255 PMID:18955505 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:40,836,121...40,864,129
Ensembl chr 6:40,836,097...40,864,128 		JBrowse link
G ENSRNOG00000070414 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 3:10,051,827...10,052,818 JBrowse link
G Lsm10 LSM10, U7 small nuclear RNA associated involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:138,365,983...138,375,856
Ensembl chr 5:138,373,119...138,377,505 		JBrowse link
G Lsm11 LSM11, U7 small nuclear RNA associated involved_in ISO
IEA 		(PMID:33230297)
GO_REF:0000107
(PMID:12975319) 		RGD
Ensembl		 PMID:12975319 PMID:33230297 GO_REF:0000107 NCBI chr10:30,367,841...30,385,956
Ensembl chr10:30,370,727...30,385,944 		JBrowse link
G Slbp stem-loop histone mRNA binding protein involved_in IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:19470752) 		GO_Central
Ensembl
RGD		 PMID:19470752 GO_REF:0000033 GO_REF:0000107 NCBI chr14:77,071,441...77,081,911
Ensembl chr14:77,071,632...77,081,906 		JBrowse link
G Slbpl stem-loop binding protein like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:26,356,478...26,363,577
Ensembl chr18:26,356,474...26,363,577 		JBrowse link
G Zfp473 zinc finger protein 473 involved_in ISO (PMID:16714279) RGD PMID:16714279 NCBI chr 1:95,222,683...95,243,328
Ensembl chr 1:95,223,433...95,243,325 		JBrowse link
mRNA alternative polyadenylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpsf6 cleavage and polyadenylation specific factor 6 involved_in ISO
IEA
IBA 		(PMID:20695905), (PMID:23187700), (PMID:29276085)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:20695905 PMID:23187700 PMID:29276085 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:52,956,589...53,001,783
Ensembl chr 7:52,956,589...52,988,122 		JBrowse link
G Cpsf7 cleavage and polyadenylation specific factor 7 involved_in ISS
IBA
ISO
IEA 		GO_REF:0000024
GO_REF:0000033
(PMID:20695905), (PMID:29276085)
GO_REF:0000107 		UniProt
GO_Central
RGD
Ensembl		 PMID:20695905 PMID:29276085 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:207,167,690...207,191,938
Ensembl chr 1:207,167,859...207,191,905 		JBrowse link
G Nudt21 nudix hydrolase 21 involved_in ISS
ISO 		GO_REF:0000024
(PMID:17098938), (PMID:20695905), (PMID:23187700), (PMID:29276085) 		UniProt
RGD		 PMID:17098938 PMID:20695905 PMID:23187700 PMID:29276085 GO_REF:0000024 NCBI chr19:10,974,800...10,993,841
Ensembl chr19:10,974,241...10,991,682 		JBrowse link
G Rbfox2 RNA binding fox-1 homolog 2 IMP RGD PMID:34731606 RGD:329845875 NCBI chr 7:108,810,627...109,054,420
Ensembl chr 7:108,810,628...109,054,691 		JBrowse link
G Ythdc1 YTH N6-methyladenosine RNA binding protein C1 acts_upstream_of_or_within ISO
IEA 		(PMID:29799838)
GO_REF:0000107 		RGD
Ensembl		 PMID:29799838 GO_REF:0000107 NCBI chr14:21,185,438...21,215,934
Ensembl chr14:21,185,440...21,216,028 		JBrowse link
positive regulation of mRNA 3'-end processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnb1 cyclin B1 IMP c-mos polyadenylation RGD PMID:15291744 RGD:1578405 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Cdc73 cell division cycle 73 involved_in ISO
ISS 		(PMID:19136632)
GO_REF:0000024 		RGD
UniProt		 PMID:19136632 GO_REF:0000024 NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656 		JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO
IEA
ISS 		(PMID:27940037)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:27940037 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572 		JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:9342333) 		UniProt
Ensembl
RGD		 PMID:9342333 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:60,416,023...60,449,004
Ensembl chr 5:60,415,982...60,449,089 		JBrowse link
G Ncbp2 nuclear cap binding protein subunit 2 involved_in ISO
IEA 		(PMID:9342333)
GO_REF:0000107 		RGD
Ensembl		 PMID:9342333 GO_REF:0000107 NCBI chr11:68,821,026...68,829,863
Ensembl chr11:68,817,740...68,851,885 		JBrowse link
regulation of mRNA 3'-end processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahcyl1 adenosylhomocysteinase-like 1 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:19224921)
GO_REF:0000107 		RGD
Ensembl		 PMID:19224921 GO_REF:0000107 NCBI chr 2:195,294,149...195,328,586
Ensembl chr 2:195,294,153...195,345,815 		JBrowse link
G Cdk9 cyclin-dependent kinase 9 involved_in ISO
IEA 		(PMID:19575011)
GO_REF:0000107 		RGD
Ensembl		 PMID:19575011 GO_REF:0000107 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410 		JBrowse link
G Cpeb1 cytoplasmic polyadenylation element binding protein 1 involved_in ISO (PMID:28383716) RGD PMID:28383716 NCBI chr 1:135,300,048...135,407,688
Ensembl chr 1:135,300,461...135,409,760 		JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 involved_in ISO (PMID:21832157) RGD PMID:21832157 NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        primary metabolic process 10727
          RNA processing 1002
            RNA 3'-end processing 99
              mRNA 3'-end processing 47
                co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway 8
                mRNA 3'-end processing by stem-loop binding and cleavage 8
                mRNA alternative polyadenylation + 5
                mitochondrial mRNA 3'-end processing 1
                negative regulation of mRNA 3'-end processing 0
                positive regulation of mRNA 3'-end processing + 5
                regulation of mRNA 3'-end processing + 9
Path 2
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        primary metabolic process 10727
          nucleobase-containing compound metabolic process 5900
            nucleic acid metabolic process 5283
              RNA metabolic process 4695
                RNA biosynthetic process 4407
                  RNA processing 1002
                    RNA 3'-end processing 99
                      mRNA 3'-end processing 47
                        co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway 8
                        mRNA 3'-end processing by stem-loop binding and cleavage 8
                        mRNA alternative polyadenylation + 5
                        mitochondrial mRNA 3'-end processing 1
                        negative regulation of mRNA 3'-end processing 0
                        positive regulation of mRNA 3'-end processing + 5
                        regulation of mRNA 3'-end processing + 9
paths to the root