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ONTOLOGY REPORT - ANNOTATIONS


Term:axon regeneration
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Accession:GO:0031103 term browser browse the term
Definition:The regrowth of axons following their loss or damage.



show annotations for term's descendants           Sort by:
axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 NOT|acts_upstream_of_or_within ISO (PMID:7798939) MGI PMID:7798939 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,392...44,218,713
JBrowse link
G APOE apolipoprotein E NOT|acts_upstream_of_or_within ISO (PMID:7798939) MGI PMID:7798939 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330
JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9009190) Ensembl
MGI
PMID:9009190 GO_REF:0000107 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G BEX1 brain expressed, X-linked 1 acts_upstream_of_or_within ISO (PMID:20731761) MGI PMID:20731761 NCBI chr  X:84,223,041...84,224,583
Ensembl chr  X:84,222,959...84,224,613
JBrowse link
G CHL1 cell adhesion molecule L1 like ISO RGD PMID:14707551 RGD:1303346 NCBI chr13:56,804,309...57,034,191
Ensembl chr13:56,804,555...57,034,181
JBrowse link
G CNTF ciliary neurotrophic factor involved_in ISO PMID:16699509 UniProt PMID:16699509 RGD:12793002 NCBI chr 2:12,492,777...12,495,401
Ensembl chr 2:12,493,169...12,496,159
JBrowse link
G CSPG5 chondroitin sulfate proteoglycan 5 ISO RGD PMID:11069908 RGD:1298825 NCBI chr13:30,387,225...30,404,181
Ensembl chr13:30,387,224...30,411,850
JBrowse link
G CTNNA1 catenin alpha 1 ISO RGD PMID:12387456 RGD:632464 NCBI chr 2:140,682,776...140,869,828
Ensembl chr 2:140,682,371...140,871,334
JBrowse link
G DAG1 dystroglycan 1 ISO RGD PMID:16228655 RGD:11537480 NCBI chr13:32,028,019...32,092,450
Ensembl chr13:32,029,522...32,092,450
JBrowse link
G DHFR dihydrofolate reductase involved_in ISO PMID:20424322 BHF-UCL PMID:20424322 RGD:10054082 NCBI chr 2:89,230,660...89,255,830 JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:21935678) MGI PMID:21935678 NCBI chr 1:31,724,290...31,796,594
Ensembl chr 1:31,722,721...31,796,595
JBrowse link
G FOLR1 folate receptor alpha involved_in ISO (MGI:4460071|PMID:20424322) BHF-UCL PMID:20424322 MGI:4460071 NCBI chr 9:6,753,513...6,760,433
Ensembl chr 9:6,757,040...6,760,402
JBrowse link
G GAP43 growth associated protein 43 involved_in IEA
IBA
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr13:144,364,314...144,458,136
Ensembl chr13:144,364,317...144,629,174
JBrowse link
G ISL1 ISL LIM homeobox 1 ISO RGD PMID:10363827 RGD:2311122 NCBI chr16:30,962,994...30,974,201
Ensembl chr16:30,963,000...30,973,907
JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:15716400 RGD:1641846 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,689...217,002,148
JBrowse link
G JAM3 junctional adhesion molecule 3 ISO RGD PMID:22950044 RGD:7488944 NCBI chr 9:60,629,245...60,738,979
Ensembl chr 9:60,613,400...60,738,924
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (PMID:15233917) MGI PMID:15233917 NCBI chr 6:153,686,425...153,687,635
Ensembl chr 6:153,685,682...153,687,636
JBrowse link
G MAG myelin associated glycoprotein involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20731761) Ensembl
MGI
PMID:20731761 GO_REF:0000107 NCBI chr 6:44,794,197...44,809,933
Ensembl chr 6:44,794,204...44,809,926
JBrowse link
G MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 involved_in ISO PMID:25944905 UniProt PMID:25944905 RGD:13673780 NCBI chr 3:40,196,873...40,241,453
Ensembl chr 3:40,196,875...40,241,291
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in ISO PMID:20424322 BHF-UCL PMID:20424322 RGD:10054082 NCBI chr14:54,546,978...54,652,780
Ensembl chr14:54,546,978...54,652,763
JBrowse link
G NEFH neurofilament heavy chain ISO RGD PMID:10646539 RGD:9698439 NCBI chr14:46,559,698...46,568,686
Ensembl chr14:46,559,860...46,568,088
JBrowse link
G NEFM neurofilament medium chain ISO RGD PMID:15206821 RGD:9698447 NCBI chr14:8,955,346...8,967,211 JBrowse link
G NREP neuronal regeneration related protein involved_in ISO
IEA
IBA
RGD
TreeGrafter
GO_Central
PMID:15485502 GO_REF:0000033 GO_REF:0000118 RGD:1540387 NCBI chr 2:117,505,851...117,867,805
Ensembl chr 2:117,838,660...117,867,801
JBrowse link
G RXRA retinoid X receptor alpha ISO RGD PMID:16782282 RGD:1643108 NCBI chr 1:273,698,842...273,797,622
Ensembl chr 1:273,705,505...273,797,620
JBrowse link
G VCAN versican ISO RGD PMID:12526031 RGD:632591 NCBI chr 2:91,682,177...91,811,674
Ensembl chr 2:91,384,391...91,811,208
JBrowse link
axon extension involved in regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAMB2 laminin subunit beta 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9396756) Ensembl
MGI
PMID:9396756 GO_REF:0000107 NCBI chr13:31,738,282...31,750,623
Ensembl chr13:31,738,286...31,750,833
JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 acts_upstream_of ISO (PMID:16142215) MGI PMID:16142215 NCBI chr 1:191,535,262...191,941,675
Ensembl chr 1:191,535,301...191,925,327
JBrowse link
G TNR tenascin R involved_in
acts_upstream_of
IEA
ISO
(PMID:16870730) Ensembl
MGI
PMID:16870730 GO_REF:0000107 NCBI chr 9:117,365,930...117,790,332
Ensembl chr 9:117,373,545...117,771,224
JBrowse link
negative regulation of axon extension involved in regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIAA0319 KIAA0319 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:28334068) MGI
Ensembl
PMID:28334068 GO_REF:0000107 NCBI chr 7:19,383,189...19,487,669
Ensembl chr 7:19,383,196...19,486,265
JBrowse link
G TNR tenascin R involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16870730) Ensembl
MGI
PMID:16870730 GO_REF:0000107 NCBI chr 9:117,365,930...117,790,332
Ensembl chr 9:117,373,545...117,771,224
JBrowse link
negative regulation of axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CERS2 ceramide synthase 2 involved_in ISO PMID:22393241 BHF-UCL PMID:22393241 RGD:11041067 NCBI chr 4:98,250,773...98,260,504
Ensembl chr 4:98,250,964...98,260,427
JBrowse link
G EPHA4 EPH receptor A4 NOT
involved_in
ISO
IEA
RGD
Ensembl
PMID:17418490 PMID:17970742 GO_REF:0000107 RGD:5688750 RGD:5688782 NCBI chr15:123,350,867...123,501,872
Ensembl chr15:123,352,816...123,503,126
JBrowse link
G FIGNL2 fidgetin like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:17,178,239...17,209,297
Ensembl chr 5:17,180,773...17,182,743
JBrowse link
G INPP5F inositol polyphosphate-5-phosphatase F involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:129,577,594...129,671,541
Ensembl chr14:129,577,567...129,669,875
JBrowse link
G KREMEN1 kringle containing transmembrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:46,254,248...46,323,355
Ensembl chr14:46,254,326...46,323,354
JBrowse link
G LRIG2 leucine rich repeats and immunoglobulin like domains 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:26651291) Ensembl
MGI
PMID:26651291 GO_REF:0000107 NCBI chr 4:107,348,662...107,511,308
Ensembl chr 4:107,348,669...107,492,516
JBrowse link
G NEO1 neogenin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:26651291) Ensembl
MGI
PMID:26651291 GO_REF:0000107 NCBI chr 7:60,064,984...60,299,892
Ensembl chr 7:60,064,994...60,300,562
JBrowse link
G PTEN phosphatase and tensin homolog involved_in ISO (MGI:5694525|PMID:26203138) ParkinsonsUK-UCL PMID:26203138 MGI:5694525 NCBI chr14:99,929,590...100,021,619 JBrowse link
G PTPRS protein tyrosine phosphatase receptor type S involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:73,607,815...73,680,685
Ensembl chr 2:73,574,854...73,680,686
JBrowse link
G RGMA repulsive guidance molecule BMP co-receptor a ISO RGD PMID:16585268 RGD:9850138 NCBI chr 7:85,921,524...85,968,887
Ensembl chr 7:85,921,594...85,968,888
JBrowse link
G RTN4R reticulon 4 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:51,579,043...51,603,180
Ensembl chr14:51,579,046...51,602,968
JBrowse link
G RTN4RL1 reticulon 4 receptor like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:48,074,375...48,146,309
Ensembl chr12:48,071,370...48,146,314
JBrowse link
G XYLT1 xylosyltransferase 1 ISO RGD PMID:18765417 RGD:2313145 NCBI chr 3:27,158,438...27,492,629
Ensembl chr 3:27,158,878...27,492,762
JBrowse link
negative regulation of collateral sprouting of intact axon in response to injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPP1 secreted phosphoprotein 1 ISO RGD PMID:15625076 RGD:1581125 NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340
JBrowse link
negative regulation of optical nerve axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RTCA RNA 3'-terminal phosphate cyclase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:117,852,776...117,875,630
Ensembl chr 4:117,852,766...117,875,684
JBrowse link
negative regulation of Schwann cell proliferation involved in axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CERS2 ceramide synthase 2 involved_in ISO PMID:22393241 BHF-UCL PMID:22393241 RGD:11041067 NCBI chr 4:98,250,773...98,260,504
Ensembl chr 4:98,250,964...98,260,427
JBrowse link
peripheral nervous system axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 ISO RGD PMID:2120218 RGD:2311210 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,392...44,218,713
JBrowse link
G APOA4 apolipoprotein A4 ISO RGD PMID:2120218 RGD:2311210 NCBI chr 9:44,201,587...44,204,072
Ensembl chr 9:44,201,508...44,204,206
JBrowse link
G APOD apolipoprotein D involved_in ISO
ISS
RGD
UniProt
PMID:2120218 GO_REF:0000024 RGD:2311210 NCBI chr13:132,514,546...132,562,594
Ensembl chr13:132,514,949...132,562,599
JBrowse link
G APOE apolipoprotein E ISO RGD PMID:2120218 RGD:2311210 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330
JBrowse link
G CALU calumenin ISO sciatic nerve RGD PMID:15509515 RGD:2316214 NCBI chr18:19,841,718...19,875,804
Ensembl chr18:19,841,719...19,875,786
JBrowse link
G CHST3 carbohydrate sulfotransferase 3 ISO RGD PMID:16495484 RGD:1600854 NCBI chr14:74,850,931...74,891,527
Ensembl chr14:74,850,931...74,891,520
JBrowse link
G MAP1B microtubule associated protein 1B ISO RGD PMID:10924960 RGD:2304028 NCBI chr16:48,403,338...48,501,453
Ensembl chr16:48,403,568...48,498,885
JBrowse link
G MMP2 matrix metallopeptidase 2 ISO RGD PMID:15026117 RGD:1582605 NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,595...30,086,982
JBrowse link
G NCAM1 neural cell adhesion molecule 1 ISO RGD PMID:15679872 RGD:2326091 NCBI chr 9:40,628,602...40,960,605
Ensembl chr 9:40,628,631...40,960,591
JBrowse link
G NEFL neurofilament light chain involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9398473) Ensembl
MGI
PMID:9398473 GO_REF:0000107 NCBI chr14:8,991,321...8,996,900
Ensembl chr14:8,991,331...8,997,112
JBrowse link
G TNC tenascin C involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16262655) Ensembl
MGI
PMID:16262655 GO_REF:0000107 NCBI chr 1:255,533,235...255,630,381
Ensembl chr 1:255,533,238...255,630,376
JBrowse link
G TSPO translocator protein ISO RGD PMID:8977149 RGD:2317177 NCBI chr 5:5,723,190...5,735,097
Ensembl chr 5:5,723,190...5,735,131
JBrowse link
positive regulation of axon extension involved in regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRP1 LDL receptor related protein 1 ISO RGD PMID:23867460 RGD:13800520 NCBI chr 5:22,435,636...22,519,276 JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 acts_upstream_of_or_within ISO (PMID:16142215) MGI PMID:16142215 NCBI chr 1:191,535,262...191,941,675
Ensembl chr 1:191,535,301...191,925,327
JBrowse link
positive regulation of axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRAF B-Raf proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24733831) Ensembl
MGI
PMID:24733831 GO_REF:0000107 NCBI chr18:8,957,963...9,132,558
Ensembl chr18:8,957,991...9,132,553
JBrowse link
G CNTF ciliary neurotrophic factor involved_in ISO
IEA
IBA
RGD
TreeGrafter
GO_Central
PMID:15574731 GO_REF:0000033 GO_REF:0000118 RGD:1626128 NCBI chr 2:12,492,777...12,495,401
Ensembl chr 2:12,493,169...12,496,159
JBrowse link
G FKBP1B FKBP prolyl isomerase 1B ISO RGD PMID:9512405 RGD:7205517 NCBI chr 3:114,623,529...114,636,200
Ensembl chr 3:114,623,532...114,634,628
JBrowse link
G FLNA filamin A involved_in ISO (MGI:6378072|PMID:26157139) CACAO PMID:26157139 MGI:6378072 NCBI chr  X:124,889,934...124,915,000
Ensembl chr  X:124,890,162...124,914,992
JBrowse link
G GRN granulin precursor involved_in ISO (MGI:5907533|PMID:28453791) UniProt PMID:28453791 MGI:5907533 NCBI chr12:18,893,772...18,900,444
Ensembl chr12:18,893,770...18,900,446
JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO RGD PMID:23349896 RGD:10046026 NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,825...137,691,058
JBrowse link
G MIF macrophage migration inhibitory factor ISO RGD PMID:12456989 RGD:1642004 NCBI chr14:49,840,303...49,841,063
Ensembl chr14:49,840,305...49,841,068
JBrowse link
G NDEL1 nudE neurodevelopment protein 1 like 1 ISO RGD PMID:18431495 RGD:2306515 NCBI chr12:53,553,897...53,640,470
Ensembl chr12:53,557,175...53,640,457
JBrowse link
G NRG1 neuregulin 1 ISO RGD PMID:20957456 RGD:10449012 NCBI chr15:52,625,550...53,688,003
Ensembl chr15:52,630,679...52,839,505
JBrowse link
G PTN pleiotrophin involved_in ISS UniProt GO_REF:0000024 NCBI chr18:12,219,708...12,309,045
Ensembl chr18:12,219,787...12,309,044
JBrowse link
G SCARF1 scavenger receptor class F member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:47,844,732...47,860,443
Ensembl chr12:47,845,555...47,856,401
JBrowse link
G STK24 serine/threonine kinase 24 ISO RGD PMID:19855390 RGD:2317003 NCBI chr11:67,458,350...67,565,642
Ensembl chr11:67,458,351...67,634,349
JBrowse link
G ZFP91 ZFP91 zinc finger protein, atypical E3 ubiquitin ligase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:12,495,548...12,532,281
Ensembl chr 2:12,495,558...12,531,633
JBrowse link
positive regulation of collateral sprouting of injured axon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRP1 LDL receptor related protein 1 ISO RGD PMID:23867460 RGD:13800520 NCBI chr 5:22,435,636...22,519,276 JBrowse link
positive regulation of sprouting of injured axon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PUM2 pumilio RNA binding family member 2 ISO RGD PMID:31606248 RGD:242905203 NCBI chr 3:117,857,930...117,965,564
Ensembl chr 3:117,883,673...117,965,293
JBrowse link
regulation of axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 acts_upstream_of_or_within ISO (PMID:26651291) MGI PMID:26651291 NCBI chr 3:126,795,513...126,853,995
Ensembl chr 3:126,795,426...126,853,995
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24733831) Ensembl
MGI
PMID:24733831 GO_REF:0000107 NCBI chr18:8,957,963...9,132,558
Ensembl chr18:8,957,991...9,132,553
JBrowse link
G KLF4 KLF transcription factor 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24129709) Ensembl
MGI
PMID:24129709 GO_REF:0000107 NCBI chr 1:248,604,817...248,609,574
Ensembl chr 1:248,604,820...248,609,035
JBrowse link
G LRIG2 leucine rich repeats and immunoglobulin like domains 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:26651291) Ensembl
MGI
PMID:26651291 GO_REF:0000107 NCBI chr 4:107,348,662...107,511,308
Ensembl chr 4:107,348,669...107,492,516
JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24733831) Ensembl
MGI
PMID:24733831 GO_REF:0000107 NCBI chr 1:164,381,892...164,469,313
Ensembl chr 1:164,381,845...164,471,226
JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 acts_upstream_of_or_within ISO (PMID:24733831) MGI PMID:24733831 NCBI chr 2:74,626,739...74,651,352
Ensembl chr 2:74,626,783...74,651,348
JBrowse link
G NEO1 neogenin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:26651291) Ensembl
MGI
PMID:26651291 GO_REF:0000107 NCBI chr 7:60,064,984...60,299,892
Ensembl chr 7:60,064,994...60,300,562
JBrowse link
G PTEN phosphatase and tensin homolog acts_upstream_of_or_within ISO (PMID:24733831) MGI PMID:24733831 NCBI chr14:99,929,590...100,021,619 JBrowse link
G PTPRF protein tyrosine phosphatase receptor type F involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21976490) Ensembl
MGI
PMID:21976490 GO_REF:0000107 NCBI chr 6:167,656,674...167,743,750
Ensembl chr 6:167,657,680...167,743,721
JBrowse link
G STK24 serine/threonine kinase 24 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:67,458,350...67,565,642
Ensembl chr11:67,458,351...67,634,349
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17799
    developmental process 6719
      anatomical structure development 6314
        regeneration 333
          neuron projection regeneration 88
            axon regeneration 73
              axon regeneration at neuromuscular junction 0
              collateral sprouting of intact axon in response to injury + 1
              negative regulation of axon regeneration + 17
              optical nerve axon regeneration + 1
              peripheral nervous system axon regeneration + 13
              positive regulation of axon regeneration + 16
              regulation of axon regeneration + 38
              sprouting of injured axon + 6
Path 2
Term Annotations click to browse term
  biological_process 17799
    developmental process 6719
      anatomical structure development 6314
        multicellular organism development 5105
          system development 4453
            nervous system development 2767
              neurogenesis 2066
                generation of neurons 1784
                  neuron differentiation 1703
                    neuron development 1401
                      neuron projection development 1232
                        neuron projection regeneration 88
                          axon regeneration 73
                            axon regeneration at neuromuscular junction 0
                            collateral sprouting of intact axon in response to injury + 1
                            negative regulation of axon regeneration + 17
                            optical nerve axon regeneration + 1
                            peripheral nervous system axon regeneration + 13
                            positive regulation of axon regeneration + 16
                            regulation of axon regeneration + 38
                            sprouting of injured axon + 6
paths to the root