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ONTOLOGY REPORT - ANNOTATIONS


Term:stress-activated protein kinase signaling cascade
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Accession:GO:0031098 term browser browse the term
Definition:The series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays a signal.
Synonyms:exact_synonym: SAPK signaling pathway;   SAPK signalling pathway;   stress-activated protein kinase signaling pathway;   stress-activated protein kinase signalling pathway
 narrow_synonym: JNK signaling pathway;   JNK signalling pathway



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stress-activated protein kinase signaling cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B1 IMP RGD PMID:16669970 RGD:1626090 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Gfral GDNF family receptor alpha like acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3610244|PMID:16086688)
GO_REF:0000107
RGD
Ensembl
PMID:16086688 GO_REF:0000107 MGI:3610244 NCBI chr 8:76,917,894...76,963,258
Ensembl chr 8:76,918,657...76,959,425
JBrowse link
G Kat7 lysine acetyltransferase 7 involved_in ISO (PMID:21856198) RGD PMID:21856198 NCBI chr10:80,221,519...80,255,590
Ensembl chr10:80,221,524...80,255,567
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 involved_in ISO (PMID:8622669) RGD PMID:8622669 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 involved_in ISO (PMID:35857590) RGD PMID:35857590 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:35857590) RGD PMID:35857590 NCBI chr 3:57,130,539...57,289,943
Ensembl chr 3:57,130,551...57,289,626
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 involved_in ISO (PMID:35857590) RGD PMID:35857590 NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395
JBrowse link
G Mapk14 mitogen activated protein kinase 14 involved_in ISO (PMID:35857590) RGD PMID:35857590 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Rhoa ras homolog family member A IMP RGD PMID:17369826 RGD:1642964 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Usp25 ubiquitin specific peptidase 25 involved_in ISO MGI:4332130 (MGI:5441108|PMID:23042150) RGD PMID:23042150 MGI:5441108 NCBI chr11:15,603,654...15,711,356
Ensembl chr11:15,603,881...15,711,348
JBrowse link
negative regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dusp10 dual specificity phosphatase 10 acts_upstream_of_or_within ISO MGI:3052343 (MGI:4366202|PMID:19696743) RGD PMID:19696743 MGI:4366202 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
JBrowse link
G Foxm1 forkhead box M1 involved_in ISO
IEA
(PMID:19696738)
GO_REF:0000107
RGD
Ensembl
PMID:19696738 GO_REF:0000107 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684
JBrowse link
G Foxo1 forkhead box O1 involved_in ISO (PMID:19696738) RGD PMID:19696738 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5009411|PMID:16023107)
BHF-UCL
RGD
PMID:16023107 GO_REF:0000024 MGI:5009411 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Igbp1 immunoglobulin binding protein 1 involved_in ISO (PMID:17438131) RGD PMID:17438131 NCBI chr  X:65,582,832...65,605,078
Ensembl chr  X:65,582,821...65,606,049
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:19545562) RGD PMID:19545562 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Pbk PDZ binding kinase acts_upstream_of_or_within ISO MGI:5293435 (MGI:5293269|PMID:21715333) RGD PMID:21715333 MGI:5293269 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISS
ISO
GO_REF:0000024
(PMID:26095851)
UniProt
RGD
PMID:26095851 GO_REF:0000024 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310
JBrowse link
G Qars1 glutaminyl-tRNA synthetase 1 involved_in ISO
IEA
(PMID:11096076)
GO_REF:0000107
RGD
Ensembl
PMID:11096076 GO_REF:0000107 NCBI chr 8:109,207,705...109,215,738
Ensembl chr 8:109,207,705...109,215,739
JBrowse link
negative regulation of stress-activated protein kinase signaling cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:35857590) RGD PMID:35857590 NCBI chr 3:57,130,539...57,289,943
Ensembl chr 3:57,130,551...57,289,626
JBrowse link
positive regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 involved_in IEA
ISO
GO_REF:0000107
(PMID:18387645)
Ensembl
RGD
PMID:18387645 GO_REF:0000107 NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608
JBrowse link
G Card9 caspase recruitment domain family, member 9 acts_upstream_of_or_within
involved_in
ISO
ISS
MGI:3698412 (MGI:3697751|PMID:17187069)
(MGI:6117948|PMID:29080677)
(PMID:17187069)
GO_REF:0000024
RGD
UniProt
PMID:17187069 PMID:29080677 GO_REF:0000024 MGI:3697751 MGI:6117948 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in ISO (MGI:5803730|PMID:27288407) RGD PMID:27288407 MGI:5803730 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:19211730 RGD:5130956 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5487533|PMID:20038207)
UniProt
RGD
PMID:20038207 GO_REF:0000024 MGI:5487533 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:17161379 RGD:5508698 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 involved_in ISO (PMID:24003225) RGD PMID:24003225 NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966
JBrowse link
G Il1a interleukin 1 alpha IDA RGD PMID:15671867 RGD:1358666 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta IMP
IDA
RGD PMID:12629164 PMID:15671867 RGD:1626685, RGD:1358666 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) RGD PMID:28436939 NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729
JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor NOT IMP RGD PMID:16222076 RGD:1599289 NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612
JBrowse link
G Klhdc10 kelch domain containing 10 involved_in IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr 4:59,021,300...59,079,118
Ensembl chr 4:59,021,310...59,074,941
JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 IMP RGD PMID:12024021 RGD:2302280 NCBI chr 7:120,526,732...120,536,982
Ensembl chr 7:120,526,732...120,536,982
JBrowse link
G Mid1 midline 1 involved_in ISO (PMID:17438131) RGD PMID:17438131 NCBI chr  X:24,116,674...24,491,205
Ensembl chr  X:24,120,293...24,248,353
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (MGI:3775161|PMID:18261938) RGD PMID:18261938 MGI:3775161 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (MGI:3775161|PMID:18261938)
(PMID:17187069)
RGD PMID:17187069 PMID:18261938 MGI:3775161 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Pdcd10 programmed cell death 10 involved_in ISO
IEA
(PMID:22652780)
GO_REF:0000107
RGD
Ensembl
PMID:22652780 GO_REF:0000107 NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2446070|MGI:2660793 (MGI:2176422|PMID:11894098), (MGI:2176424|PMID:11894097), (MGI:3775161|PMID:18261938) RGD PMID:11894097 PMID:11894098 PMID:18261938 MGI:2176422 MGI:2176424 MGI:3775161 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (MGI:5803730|PMID:27288407) RGD PMID:27288407 MGI:5803730 NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171
JBrowse link
G Sema4c semaphorin 4C involved_in ISO (PMID:17498836) RGD PMID:17498836 NCBI chr 9:38,791,668...38,802,171
Ensembl chr 9:38,791,670...38,802,128
JBrowse link
G Stk25 serine/threonine kinase 25 involved_in ISO (PMID:22652780) RGD PMID:22652780 NCBI chr 9:94,161,834...94,174,095
Ensembl chr 9:94,161,836...94,174,244
JBrowse link
G Taok1 TAO kinase 1 involved_in ISO
ISS
(PMID:17396146)
GO_REF:0000024
RGD
UniProt
PMID:17396146 GO_REF:0000024 NCBI chr10:62,373,072...62,465,295
Ensembl chr10:62,381,404...62,465,766
JBrowse link
G Taok2 TAO kinase 2 involved_in ISO
IEA
ISS
(PMID:17396146)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:17396146 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:181,475,708...181,494,738
Ensembl chr 1:181,475,711...181,494,613
JBrowse link
G Taok3 TAO kinase 3 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:17396146)
UniProt
Ensembl
RGD
PMID:17396146 GO_REF:0000024 GO_REF:0000107 NCBI chr12:39,312,354...39,473,656
Ensembl chr12:39,314,027...39,461,244
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:17192487)
AgBase
RGD
PMID:17192487 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3775161|PMID:18261938)
GO_REF:0000107
RGD
Ensembl
PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000067941 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr11:42,352,734...42,354,134 JBrowse link
G Fas Fas cell surface death receptor involved_in ISO
IBA
IEA
(PMID:11096076)
GO_REF:0000033
GO_REF:0000118
RGD
GO_Central
TreeGrafter
PMID:11096076 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist NOT|involved_in ISO (MGI:5318033|PMID:12135612) RGD PMID:12135612 MGI:5318033 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5009198|PMID:10945608)
BHF-UCL
RGD
PMID:10945608 GO_REF:0000024 MGI:5009198 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in TAS
IEA
PMID:19565474
GO_REF:0000117
UniProt PMID:19565474 GO_REF:0000117, RGD:8553538 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 involved_in TAS
IEA
PMID:19565474
GO_REF:0000117
UniProt PMID:19565474 GO_REF:0000117, RGD:8553538 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in TAS
IEA
PMID:19565474
GO_REF:0000117
UniProt PMID:19565474 GO_REF:0000117, RGD:8553538 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in TAS
IEA
PMID:19565474
GO_REF:0000117
UniProt PMID:19565474 GO_REF:0000117, RGD:8553538 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nbr1 NBR1, autophagy cargo receptor involved_in IEA
ISO
GO_REF:0000107
(MGI:4818844|PMID:20616007)
Ensembl
RGD
PMID:20616007 GO_REF:0000107 MGI:4818844 NCBI chr10:86,477,775...86,506,418
Ensembl chr10:86,478,290...86,506,412
JBrowse link
G Prdx1 peroxiredoxin 1 acts_upstream_of_or_within ISO (MGI:3695235|PMID:16880205) RGD PMID:16880205 MGI:3695235 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Tirap TIR domain containing adaptor protein involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432
JBrowse link
G Tnfrsf22 tumor necrosis factor receptor superfamily, member 22 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 1:198,840,452...198,860,713
Ensembl chr 1:198,840,453...198,856,309
JBrowse link
G Tnfrsf26 tumor necrosis factor receptor superfamily, member 26 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 1:198,802,968...198,823,032
Ensembl chr 1:198,802,971...198,823,418
JBrowse link
regulation of stress-activated protein kinase signaling cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033 (MGI:3789238|PMID:16079796) RGD PMID:16079796 MGI:3789238 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110
JBrowse link
stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen IDA RGD PMID:21367774 RGD:5129174 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Card9 caspase recruitment domain family, member 9 acts_upstream_of ISO MGI:3698412 (MGI:3697751|PMID:17187069) RGD PMID:17187069 MGI:3697751 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
JBrowse link
G Cd2ap CD2-associated protein acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:2664945 (MGI:3053500|PMID:15213232)
GO_REF:0000107
RGD
Ensembl
PMID:15213232 GO_REF:0000107 MGI:3053500 NCBI chr 9:18,086,744...18,182,744
Ensembl chr 9:18,086,984...18,182,199
JBrowse link
G Cryab crystallin, alpha B IMP RGD PMID:18420382 RGD:2303631 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Dusp10 dual specificity phosphatase 10 acts_upstream_of ISO MGI:3052343 (MGI:4366202|PMID:19696743) RGD PMID:19696743 MGI:4366202 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 involved_in ISO (PMID:8663524), (PMID:9218798) RGD PMID:8663524 PMID:9218798 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in IDA
IEA
IBA
ISO
PMID:10051439
GO_REF:0000117
GO_REF:0000033
(PMID:9535930)
UniProt
GO_Central
RGD
PMID:9535930 PMID:10051439 GO_REF:0000033 GO_REF:0000117, RGD:2298561 NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222
JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 involved_in ISO (PMID:11726277) RGD PMID:11726277 NCBI chr11:79,094,087...79,235,181
Ensembl chr11:79,097,247...79,235,181
JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISS
ISO
GO_REF:0000024
(PMID:11836244), (PMID:20559024), (PMID:32289254), (PMID:32610081)
(MGI:6468889|PMID:32289254)
UniProt
RGD
PMID:11836244 PMID:20559024 PMID:32289254 PMID:32610081 GO_REF:0000024 MGI:6468889 NCBI chr 3:57,130,539...57,289,943
Ensembl chr 3:57,130,551...57,289,626
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO (PMID:9079627) RGD PMID:9079627 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in ISO
IEA
(PMID:11096076)
GO_REF:0000107
RGD
Ensembl
PMID:11096076 GO_REF:0000107 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 involved_in ISO (PMID:35857590), (PMID:8663524) RGD PMID:8663524 PMID:35857590 NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395
JBrowse link
G Mapk13 mitogen activated protein kinase 13 involved_in ISO
ISS
IEA
(PMID:9218798)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:9218798 GO_REF:0000024 GO_REF:0000107 NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222
JBrowse link
G Mapk14 mitogen activated protein kinase 14 involved_in IDA
ISO
IEA
(PMID:35857590)
GO_REF:0000107
RGD
Ensembl
PMID:35857590 PMID:16407200 GO_REF:0000107, RGD:1580544 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 involved_in ISO
IEA
(PMID:11096076)
GO_REF:0000107
RGD
Ensembl
PMID:11096076 GO_REF:0000107 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of ISO (MGI:3775161|PMID:18261938) RGD PMID:18261938 MGI:3775161 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of ISO (MGI:3775161|PMID:18261938) RGD PMID:18261938 MGI:3775161 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Pbk PDZ binding kinase acts_upstream_of ISO MGI:5293435 (MGI:5293269|PMID:21715333) RGD PMID:21715333 MGI:5293269 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of ISO MGI:2446070|MGI:2660793 (MGI:2176422|PMID:11894098), (MGI:2176424|PMID:11894097), (MGI:3775161|PMID:18261938) RGD PMID:11894097 PMID:11894098 PMID:18261938 MGI:2176422 MGI:2176424 MGI:3775161 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
JBrowse link
G Taok2 TAO kinase 2 involved_in ISO
IEA
ISS
(PMID:11279118)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:11279118 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:181,475,708...181,494,738
Ensembl chr 1:181,475,711...181,494,613
JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of
involved_in
ISO
IEA
(MGI:3775161|PMID:18261938)
GO_REF:0000107
RGD
Ensembl
PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20328
    cellular process 18788
      cellular response to stimulus 9037
        cellular response to stress 2047
          stress-activated protein kinase signaling cascade 68
            negative regulation of stress-activated protein kinase signaling cascade + 11
            positive regulation of stress-activated protein kinase signaling cascade + 26
            regulation of stress-activated protein kinase signaling cascade + 50
            stress-activated MAPK cascade + 61
Path 2
Term Annotations click to browse term
  biological_process 20328
    biological regulation 13627
      regulation of biological process 13221
        regulation of cellular process 12679
          signal transduction 7176
            intracellular signal transduction 2823
              stress-activated protein kinase signaling cascade 68
                negative regulation of stress-activated protein kinase signaling cascade + 11
                positive regulation of stress-activated protein kinase signaling cascade + 26
                regulation of stress-activated protein kinase signaling cascade + 50
                stress-activated MAPK cascade + 61
paths to the root