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ONTOLOGY REPORT - ANNOTATIONS

Term:stress-activated protein kinase signaling cascade
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Accession:GO:0031098 term browser browse the term
Definition:The series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays a signal.
Synonyms:exact_synonym: SAPK signaling pathway;   SAPK signalling pathway;   stress-activated protein kinase signaling pathway;   stress-activated protein kinase signalling pathway
 narrow_synonym: JNK signaling pathway;   JNK signalling pathway


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stress-activated protein kinase signaling cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B1 IMP RGD PMID:16669970 RGD:1626090 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Ccdc88c coiled-coil domain containing 88C involved_in ISO (PMID:25062847) RGD PMID:25062847 NCBI chr 6:120,169,752...120,289,459
Ensembl chr 6:120,169,738...120,289,555 		JBrowse link
G Gfral GDNF family receptor alpha like acts_upstream_of_or_within ISO (MGI:3610244|PMID:16086688) RGD PMID:16086688 MGI:3610244 NCBI chr 8:76,917,894...76,963,349
Ensembl chr 8:76,918,657...76,959,425 		JBrowse link
G Kat7 lysine acetyltransferase 7 involved_in ISO (PMID:21856198) RGD PMID:21856198 NCBI chr10:80,221,519...80,255,590
Ensembl chr10:80,221,524...80,255,567 		JBrowse link
G Rhoa ras homolog family member A IMP RGD PMID:17369826 RGD:1642964 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Usp25 ubiquitin specific peptidase 25 involved_in ISO MGI:4332130 (MGI:5441108|PMID:23042150) RGD PMID:23042150 MGI:5441108 NCBI chr11:15,603,654...15,711,356
Ensembl chr11:15,603,881...15,711,348 		JBrowse link
JNK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 involved_in ISO MGI:3720850 (MGI:3818095|PMID:18802055), (MGI:5007596|PMID:21533046) RGD PMID:18802055 PMID:21533046 MGI:3818095 MGI:5007596 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Card9 caspase recruitment domain family, member 9 acts_upstream_of ISO MGI:3698412 (MGI:3697751|PMID:17187069) RGD PMID:17187069 MGI:3697751 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Casr calcium-sensing receptor IMP RGD PMID:15084499 RGD:1358486 NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811 		JBrowse link
G Cdc42ep5 CDC42 effector protein 5 acts_upstream_of_or_within ISO (MGI:1929482|PMID:10490598) RGD PMID:10490598 MGI:1929482 NCBI chr 1:70,035,921...70,038,990 JBrowse link
G Daxx death-domain associated protein involved_in ISO (PMID:9215629) RGD PMID:9215629 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Dusp19 dual specificity phosphatase 19 acts_upstream_of_or_within ISO (MGI:2182169|PMID:11959862) RGD PMID:11959862 MGI:2182169 NCBI chr 3:65,538,424...65,554,465
Ensembl chr 3:65,538,420...65,553,534 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor acts_upstream_of_or_within ISO MGI:1932102 (MGI:3654809|PMID:16319174) RGD PMID:16319174 MGI:3654809 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Fgf12 fibroblast growth factor 12 acts_upstream_of_or_within ISO UniProtKB:Q9ERE9 (PMID:12815063) RGD PMID:12815063 NCBI chr11:71,997,049...72,564,965
Ensembl chr11:71,997,099...72,562,607 		JBrowse link
G Fgf14 fibroblast growth factor 14 acts_upstream_of_or_within ISO UniProtKB:Q9ERE9 (PMID:12815063) RGD PMID:12815063 NCBI chr15:101,045,038...101,679,888
Ensembl chr15:101,045,036...101,679,900 		JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 acts_upstream_of_or_within ISO (MGI:1859506|PMID:10747961) RGD PMID:10747961 MGI:1859506 NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507 		JBrowse link
G Il1b interleukin 1 beta acts_upstream_of ISO MGI:1346877 (MGI:3607973|PMID:16260493) RGD PMID:16260493 MGI:3607973 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il3 interleukin 3 acts_upstream_of ISO (MGI:3032484|PMID:14967141) RGD PMID:14967141 MGI:3032484 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 IMP RGD PMID:15890643 RGD:1579817 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 IMP RGD PMID:15890643 RGD:1579817 NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:19302196) RGD PMID:19302196 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Maged1 MAGE family member D1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:59,422,715...59,429,381
Ensembl chr  X:59,422,717...59,429,364 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 IDA RGD PMID:17064355 RGD:2298577 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in IDA
ISO		 (MGI:2182169|PMID:11959862) RGD PMID:11959862 PMID:10051439 PMID:17064355 PMID:15680699 PMID:11849756 MGI:2182169, RGD:2298561, RGD:2298577, RGD:2298567, RGD:2298565 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 acts_upstream_of_or_within ISO (MGI:3032484|PMID:14967141) RGD PMID:14967141 MGI:3032484 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 involved_in IDA
ISO		 (PMID:15258589) RGD PMID:15258589 PMID:15680699 PMID:17064355 RGD:2298567, RGD:2298577 NCBI chr 1:202,975,353...202,988,655
Ensembl chr 1:202,975,353...202,988,652 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 involved_in ISO
IEA		 (MGI:5810221|PMID:27511108)
GO_REF:0000002
GO_REF:0000107		 RGD
InterPro
Ensembl		 PMID:27511108 GO_REF:0000002 GO_REF:0000107 MGI:5810221 NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789 		JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 involved_in ISO
IBA		 (PMID:11726277), (PMID:9353328)
PMID:21873635
(MGI:5810221|PMID:27511108)		 RGD PMID:9353328 PMID:11726277 PMID:27511108 PMID:21873635 MGI:5810221, RGD:13792537 NCBI chr11:79,094,087...79,235,181
Ensembl chr11:79,097,247...79,235,181 		JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:11836244) RGD PMID:11836244 NCBI chr 3:57,128,561...57,289,943
Ensembl chr 3:57,130,551...57,289,626 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in ISO
IDA		 (PMID:11959862), (PMID:21771788)
(PMID:11959862), (PMID:21771788), (PMID:22095282)		 RGD PMID:11959862 PMID:21771788 PMID:22095282 PMID:12524169 RGD:2298708 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in
acts_upstream_of		 ISO
IBA
ISS		 (PMID:9079627)
MGI:104798|MGI:96536|MGI:96824 (MGI:3607973|PMID:16260493)
(MGI:6162308|PMID:29291351)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:9079627 PMID:16260493 PMID:29291351 PMID:21873635 GO_REF:0000024 MGI:3607973 MGI:6162308, RGD:13792537 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Map4k1 mitogen activated protein kinase kinase kinase kinase 1 involved_in ISO (PMID:8824585) RGD PMID:8824585 NCBI chr 1:84,270,951...84,292,496
Ensembl chr 1:84,271,069...84,292,493 		JBrowse link
G Mapk10 mitogen activated protein kinase 10 involved_in IDA
IBA
ISO
ISS		 PMID:21873635
(MGI:1098190|PMID:9349820)
GO_REF:0000024		 RGD
UniProt		 PMID:9349820 PMID:10051439 PMID:21873635 PMID:15680699 GO_REF:0000024 MGI:1098190, RGD:2298561, RGD:13792537, RGD:2298567 NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 involved_in
acts_upstream_of_or_within		 ISO
IBA
ISS		 (PMID:8654373)
(MGI:3573812|PMID:15579909)
PMID:21873635
(MGI:1855744|PMID:10811224)
GO_REF:0000024		 RGD
UniProt		 PMID:8654373 PMID:10811224 PMID:15579909 PMID:21873635 GO_REF:0000024 MGI:1855744 MGI:3573812, RGD:13792537 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 acts_upstream_of_or_within ISO (MGI:1888439|PMID:10827199) RGD PMID:10827199 MGI:1888439 NCBI chr 7:120,526,732...120,536,982
Ensembl chr 7:120,526,732...120,536,982 		JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 acts_upstream_of_or_within ISO (MGI:1352260|PMID:10629060) RGD PMID:10629060 MGI:1352260 NCBI chr10:13,918,417...13,958,335
Ensembl chr10:13,918,400...13,958,273 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 involved_in IDA
IBA
ISO		 PMID:21873635
(PMID:8654373)		 RGD PMID:8654373 PMID:10051439 PMID:21873635 RGD:2298561, RGD:13792537 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of IMP
ISO		 MGI:2385681 (MGI:2669022|PMID:12855817) RGD PMID:12855817 PMID:15890643 MGI:2669022, RGD:1579817 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in ISO (MGI:3818095|PMID:18802055) RGD PMID:18802055 MGI:3818095 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of ISO (MGI:3775161|PMID:18261938) RGD PMID:18261938 MGI:3775161 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of ISO (MGI:3775161|PMID:18261938) RGD PMID:18261938 MGI:3775161 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Nox1 NADPH oxidase 1 acts_upstream_of
involved_in		 ISO
IEA		 MGI:3616995 (MGI:4881403|PMID:19661248)
GO_REF:0000107		 RGD
Ensembl		 PMID:19661248 GO_REF:0000107 MGI:4881403 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:2155187|PMID:11562357)		 Ensembl
RGD		 PMID:11562357 GO_REF:0000107 MGI:2155187 NCBI chr 1:85,720,812...85,749,079
Ensembl chr 1:85,720,812...85,749,078 		JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 acts_upstream_of ISO MGI:1100089 (MGI:5308511|PMID:22073305) RGD PMID:22073305 MGI:5308511 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808 		JBrowse link
G Ptger4 prostaglandin E receptor 4 involved_in IDA PMID:19233324 UniProt PMID:19233324 RGD:8554254 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Ptk2 protein tyrosine kinase 2 IMP RGD PMID:12782622 RGD:2292618 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of ISO MGI:2446070|MGI:2660793 (MGI:2176422|PMID:11894098), (MGI:2176424|PMID:11894097), (MGI:3775161|PMID:18261938) RGD PMID:11894097 PMID:11894098 PMID:18261938 MGI:2176422 MGI:2176424 MGI:3775161 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 acts_upstream_of_or_within ISO (MGI:3042073|PMID:12839624) RGD PMID:12839624 MGI:3042073 NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152 		JBrowse link
G Sh3bp5 SH3-domain binding protein 5 NAS RGD PMID:12167088 RGD:737651 NCBI chr16:6,583,462...6,678,344
Ensembl chr16:6,583,465...6,698,975 		JBrowse link
G Smad3 SMAD family member 3 involved_in ISO (MGI:3818095|PMID:18802055) RGD PMID:18802055 MGI:3818095 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Spag9 sperm associated antigen 9 acts_upstream_of_or_within ISO (MGI:4835955|PMID:12391307) RGD PMID:12391307 MGI:4835955 NCBI chr10:78,943,439...79,077,797
Ensembl chr10:78,943,479...79,077,797 		JBrowse link
G Stk3 serine/threonine kinase 3 acts_upstream_of
involved_in		 ISO
IEA		 MGI:104798|MGI:1929004 (MGI:4420852|PMID:20080598)
GO_REF:0000107		 RGD
Ensembl		 PMID:20080598 GO_REF:0000107 MGI:4420852 NCBI chr 7:66,053,209...66,323,292
Ensembl chr 7:66,052,345...66,323,233 		JBrowse link
G Stradb STE20 related adaptor beta acts_upstream_of_or_within ISO (MGI:2656105|PMID:12574163) RGD PMID:12574163 MGI:2656105 NCBI chr 9:60,414,182...60,433,084
Ensembl chr 9:60,414,182...60,433,084 		JBrowse link
G Tlr3 toll-like receptor 3 involved_in
acts_upstream_of		 ISO (MGI:3818095|PMID:18802055)
(MGI:3607973|PMID:16260493)		 RGD PMID:16260493 PMID:18802055 MGI:3607973 MGI:3818095 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of
involved_in		 ISO
IEA		 MGI:1346877 (MGI:3607973|PMID:16260493), (MGI:3775161|PMID:18261938)
GO_REF:0000107		 RGD
Ensembl		 PMID:16260493 PMID:18261938 GO_REF:0000107 MGI:3607973 MGI:3775161 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr7 toll-like receptor 7 involved_in ISO (MGI:3818095|PMID:18802055) RGD PMID:18802055 MGI:3818095 NCBI chr  X:27,027,380...27,054,309
Ensembl chr  X:27,027,425...27,054,754 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO MGI:1341850 (MGI:3689241|PMID:17015619)
MGI:1346877 (MGI:3607973|PMID:16260493), (MGI:4420852|PMID:20080598)		 RGD PMID:16260493 PMID:17015619 PMID:20080598 MGI:3607973 MGI:3689241 MGI:4420852 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of
involved_in		 ISO
IEA		 MGI:109520 (MGI:5308511|PMID:22073305)
GO_REF:0000107		 RGD
Ensembl		 PMID:22073305 GO_REF:0000107 MGI:5308511 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Traf6 TNF receptor associated factor 6 IMP RGD PMID:15890643 RGD:1579817 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trib1 tribbles pseudokinase 1 involved_in ISO (PMID:17452330) RGD PMID:17452330 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO (MGI:3042073|PMID:12839624) RGD PMID:12839624 MGI:3042073 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
JUN phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapk10 mitogen activated protein kinase 10 IDA RGD PMID:10597270 RGD:7495842 NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 acts_upstream_of_or_within
involved_in		 ISO MGI:2384141 (MGI:3032484|PMID:14967141)
(PMID:14967141)
(PMID:21095239)		 RGD PMID:14967141 PMID:21095239 MGI:3032484 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 acts_upstream_of_or_within ISO (MGI:1306759|PMID:9235893) RGD PMID:9235893 MGI:1306759 NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IMP RGD PMID:16942465 RGD:2304233 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
negative regulation of JNK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aida axin interactor, dorsalization associated involved_in ISO UniProtKB:O35625 (MGI:3799599|PMID:17681137) RGD PMID:17681137 MGI:3799599 NCBI chr13:94,940,311...94,967,920
Ensembl chr13:94,939,741...94,967,920 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 IDA RGD PMID:17064355 RGD:2298577 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (MGI:3693042|PMID:17081782) RGD PMID:17081782 MGI:3693042 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase involved_in ISO
ISS		 (PMID:29291351)
(MGI:6162308|PMID:29291351)
GO_REF:0000024		 RGD
UniProt		 PMID:29291351 GO_REF:0000024 MGI:6162308 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 involved_in IBA
ISO		 PMID:21873635
(MGI:5437437|PMID:17197390)
(PMID:17197390)		 RGD PMID:17197390 PMID:21873635 MGI:5437437, RGD:13792537 NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906 		JBrowse link
G Dusp10 dual specificity phosphatase 10 involved_in
acts_upstream_of_or_within		 ISO (PMID:10391943)
MGI:3052343 (MGI:3051749|PMID:15306813)		 RGD PMID:10391943 PMID:15306813 MGI:3051749 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Dusp19 dual specificity phosphatase 19 involved_in ISO (MGI:2182169|PMID:11959862) RGD PMID:11959862 MGI:2182169 NCBI chr 3:65,538,424...65,554,465
Ensembl chr 3:65,538,420...65,553,534 		JBrowse link
G Dusp3 dual specificity phosphatase 3 involved_in IBA
ISO		 PMID:21873635
(PMID:11085983), (PMID:19010898)		 RGD PMID:11085983 PMID:19010898 PMID:21873635 RGD:13792537 NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:19781631) RGD PMID:19781631 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Fktn fukutin involved_in ISO (PMID:18808525) RGD PMID:18808525 NCBI chr 5:68,339,803...68,396,412
Ensembl chr 5:68,340,028...68,396,409 		JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (PMID:11931768)
(MGI:6148454|PMID:22424771)		 RGD PMID:11931768 PMID:22424771 MGI:6148454 NCBI chr10:54,637,360...54,640,542
Ensembl chr10:54,637,455...54,640,650 		JBrowse link
G Hdac3 histone deacetylase 3 involved_in ISO (PMID:11931768) RGD PMID:11931768 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856 		JBrowse link
G Itch itchy E3 ubiquitin protein ligase involved_in ISO (MGI:3774677|PMID:18246070) RGD PMID:18246070 MGI:3774677 NCBI chr 3:143,642,348...143,733,745
Ensembl chr 3:143,645,637...143,733,543 		JBrowse link
G Klhl31 kelch-like family member 31 involved_in ISO
IBA		 (PMID:18719355)
PMID:21873635		 RGD PMID:18719355 PMID:21873635 RGD:13792537 NCBI chr 8:78,515,514...78,538,873
Ensembl chr 8:78,515,514...78,538,873 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 IMP RGD PMID:12064607 RGD:1299562 NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884 		JBrowse link
G Marveld3 MARVEL domain containing 3 acts_upstream_of_or_within ISO (PMID:24567356) RGD PMID:24567356 NCBI chr19:37,908,727...37,923,420
Ensembl chr19:37,905,638...37,923,420 		JBrowse link
G Mecom MDS1 and EVI1 complex locus involved_in ISO (PMID:10856240) RGD PMID:10856240 NCBI chr 2:112,909,353...113,464,583
Ensembl chr 2:112,909,321...113,464,590 		JBrowse link
G Men1 menin 1 involved_in ISO (PMID:12226747) RGD PMID:12226747 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871 		JBrowse link
G Ncor1 nuclear receptor co-repressor 1 involved_in ISO (PMID:11931768) RGD PMID:11931768 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032 		JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 acts_upstream_of_or_within ISO MGI:1100089 (MGI:5308511|PMID:22073305) RGD PMID:22073305 MGI:5308511 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808 		JBrowse link
G Per1 period circadian regulator 1 involved_in IMP PMID:24447840 UniProt PMID:24447840 RGD:8655527 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISS GO_REF:0000024 ParkinsonsUK-UCL GO_REF:0000024 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Prmt1 protein arginine methyltransferase 1 involved_in ISO
ISS		 (PMID:22095282)
GO_REF:0000024		 RGD
UniProt		 PMID:22095282 GO_REF:0000024 NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345 		JBrowse link
G Sfrp4 secreted frizzled-related protein 4 IDA RGD PMID:18567805 RGD:4107045 NCBI chr17:45,278,867...45,330,806
Ensembl chr17:45,234,097...45,330,736 		JBrowse link
G Sh3rf2 SH3 domain containing ring finger 2 involved_in IMP PMID:22128169 UniProt PMID:22128169 RGD:13673844 NCBI chr18:34,045,715...34,148,342
Ensembl chr18:34,046,879...34,146,856 		JBrowse link
G Sirpa signal-regulatory protein alpha involved_in ISO (MGI:3760575|PMID:17954568) RGD PMID:17954568 MGI:3760575 NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098 		JBrowse link
G Taok3 TAO kinase 3 involved_in ISO
IEA		 (PMID:10559204)
GO_REF:0000107		 RGD
Ensembl		 PMID:10559204 GO_REF:0000107 NCBI chr12:39,314,027...39,394,243
Ensembl chr12:39,314,027...39,461,244 		JBrowse link
G Zmynd11 zinc finger, MYND-type containing 11 involved_in ISO (PMID:20732415) RGD PMID:20732415 NCBI chr17:60,542,669...60,631,913
Ensembl chr17:60,543,077...60,631,902 		JBrowse link
negative regulation of JUN kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aida axin interactor, dorsalization associated acts_upstream_of_or_within ISO (MGI:3799599|PMID:17681137)
(PMID:17681137)		 RGD PMID:17681137 MGI:3799599 NCBI chr13:94,940,311...94,967,920
Ensembl chr13:94,939,741...94,967,920 		JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 involved_in ISO
ISS		 (PMID:24512202)
GO_REF:0000024		 RGD
UniProt		 PMID:24512202 GO_REF:0000024 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967 		JBrowse link
G Dusp10 dual specificity phosphatase 10 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:10391943)
MGI:3052343 (MGI:3051749|PMID:15306813)
PMID:21873635		 RGD PMID:10391943 PMID:15306813 PMID:21873635 MGI:3051749, RGD:13792537 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Dusp16 dual specificity phosphatase 16 involved_in ISO (PMID:11489891) RGD PMID:11489891 NCBI chr 4:167,546,780...167,629,949
Ensembl chr 4:167,548,155...167,629,980 		JBrowse link
G Dusp19 dual specificity phosphatase 19 involved_in ISO (MGI:2182169|PMID:11959862) RGD PMID:11959862 MGI:2182169 NCBI chr 3:65,538,424...65,554,465
Ensembl chr 3:65,538,420...65,553,534 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3721484|PMID:12646564), (MGI:5009198|PMID:10945608), (MGI:5009411|PMID:16023107)
(PMID:16636664)		 BHF-UCL
RGD		 PMID:10945608 PMID:12646564 PMID:16023107 PMID:16636664 GO_REF:0000024 MGI:3721484 MGI:5009198 MGI:5009411 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hipk3 homeodomain interacting protein kinase 3 involved_in ISO (MGI:1913166|PMID:11034606) RGD PMID:11034606 MGI:1913166 NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:90,800,296...90,867,759 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 involved_in IMP PMID:21076496 RGD
UniProt		 PMID:12064607 PMID:21076496 RGD:1299562, RGD:13673827 NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884 		JBrowse link
G Nppa natriuretic peptide A involved_in ISO (PMID:22399583) RGD PMID:22399583 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Pdcd4 programmed cell death 4 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23991106) RGD PMID:23991106 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Serpinb3 serpin family B member 3 involved_in ISO (PMID:21383048) RGD PMID:21383048 NCBI chr13:23,274,120...23,280,082
Ensembl chr13:23,274,484...23,313,682 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:108078|MGI:1860298 (MGI:3839161|PMID:19300477)		 Ensembl
RGD		 PMID:19300477 GO_REF:0000107 MGI:3839161 NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within ISO MGI:1860298|MGI:892014 (MGI:3839161|PMID:19300477) RGD PMID:19300477 MGI:3839161 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Sfrp5 secreted frizzled-related protein 5 acts_upstream_of_or_within ISO MGI:108078|MGI:892014 (MGI:3839161|PMID:19300477) RGD PMID:19300477 MGI:3839161 NCBI chr 1:241,006,762...241,011,224
Ensembl chr 1:241,006,762...241,011,224 		JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO (MGI:3574697|PMID:15483136) RGD PMID:15483136 MGI:3574697 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
negative regulation of p38MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyld CYLD lysine 63 deubiquitinase involved_in ISS
ISO		 GO_REF:0000024
(PMID:29291351)
(MGI:6162308|PMID:29291351)		 UniProt
RGD		 PMID:29291351 GO_REF:0000024 MGI:6162308 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in ISO
IEA		 (PMID:20551903)
GO_REF:0000107		 RGD
Ensembl		 PMID:20551903 GO_REF:0000107 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689 		JBrowse link
G Dusp1 dual specificity phosphatase 1 involved_in ISO
IBA		 (PMID:22991462)
PMID:21873635		 RGD PMID:22991462 PMID:21873635 RGD:13792537 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp10 dual specificity phosphatase 10 involved_in ISO (PMID:10391943) RGD PMID:10391943 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Ezr ezrin involved_in ISO (PMID:20551903) RGD PMID:20551903 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 acts_upstream_of_or_within ISO MGI:1346865 (MGI:3822965|PMID:18681888) RGD PMID:18681888 MGI:3822965 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224 		JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:22696064) RGD PMID:22696064 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO
IBA		 (PMID:23991106)
PMID:21873635
(MGI:5640942|PMID:23991106)		 RGD PMID:23991106 PMID:21873635 MGI:5640942, RGD:13792537 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6695687|PMID:31900229) RGD PMID:31900229 MGI:6695687 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
negative regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dusp10 dual specificity phosphatase 10 acts_upstream_of_or_within ISO MGI:3052343 (MGI:4366202|PMID:19696743) RGD PMID:19696743 MGI:4366202 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Foxm1 forkhead box M1 involved_in ISO
IEA		 (PMID:19696738)
GO_REF:0000107		 RGD
Ensembl		 PMID:19696738 GO_REF:0000107 NCBI chr 4:161,639,561...161,652,012
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Foxo1 forkhead box O1 involved_in ISO (PMID:19696738) RGD PMID:19696738 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5009411|PMID:16023107)		 BHF-UCL
RGD		 PMID:16023107 GO_REF:0000024 MGI:5009411 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Igbp1 immunoglobulin binding protein 1 involved_in ISO (PMID:17438131) RGD PMID:17438131 NCBI chr  X:65,582,832...65,605,078
Ensembl chr  X:65,582,821...65,606,049 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:19545562) RGD PMID:19545562 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Pbk PDZ binding kinase acts_upstream_of_or_within ISO MGI:5293435 (MGI:5293269|PMID:21715333) RGD PMID:21715333 MGI:5293269 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014 		JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISS
ISO		 GO_REF:0000024
(PMID:26095851)		 UniProt
RGD		 PMID:26095851 GO_REF:0000024 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310 		JBrowse link
G Qars1 glutaminyl-tRNA synthetase 1 involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr 8:109,207,705...109,215,738
Ensembl chr 8:109,207,705...109,215,739 		JBrowse link
p38MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 involved_in ISO MGI:2443472|MGI:3720850|MGI:3842320 (MGI:3719954|PMID:17699753), (MGI:4420477|PMID:19948881), (MGI:5007596|PMID:21533046) RGD PMID:17699753 PMID:19948881 PMID:21533046 MGI:3719954 MGI:4420477 MGI:5007596 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Atf7 activating transcription factor 7 involved_in ISO MGI:109349 (MGI:3719954|PMID:17699753) RGD PMID:17699753 MGI:3719954 NCBI chr 7:133,660,491...133,750,902
Ensembl chr 7:133,663,294...133,750,848 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:2135670 (MGI:4437389|PMID:20053668) RGD PMID:20053668 MGI:4437389 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:16116184) RGD PMID:16116184 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 involved_in ISO (PMID:22696064) RGD PMID:22696064 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492 		JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:11836244) RGD PMID:11836244 NCBI chr 3:57,128,561...57,289,943
Ensembl chr 3:57,130,551...57,289,626 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 acts_upstream_of_or_within ISO (PMID:22337877) RGD PMID:22337877 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000002
(MGI:5526919|PMID:22847234)
GO_REF:0000107		 UniProt
InterPro
RGD
Ensembl		 PMID:22847234 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 MGI:5526919 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 acts_upstream_of_or_within ISO (MGI:5532755|PMID:24020373) RGD PMID:24020373 MGI:5532755 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457 		JBrowse link
G Nr2c2 nuclear receptor subfamily 2, group C, member 2 acts_upstream_of_or_within ISO (PMID:22337877) RGD PMID:22337877 NCBI chr 4:124,610,216...124,666,813
Ensembl chr 4:124,608,960...124,661,902 		JBrowse link
G Pbk PDZ binding kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014 		JBrowse link
G Zfp36 zinc finger protein 36 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5784995|PMID:11533235)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:11533235 GO_REF:0000024 GO_REF:0000107 MGI:5784995 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564 		JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5784987|PMID:17889962)		 UniProt
RGD		 PMID:17889962 GO_REF:0000024 MGI:5784987 NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748 		JBrowse link
positive regulation of JNK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in ISO ComplexPortal:CPX-1134|UniProtKB:P10749 (PMID:20739563) RGD PMID:20739563 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Ankrd6 ankyrin repeat domain 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:47,197,981...47,343,183
Ensembl chr 5:47,202,873...47,343,090 		JBrowse link
G App amyloid beta precursor protein involved_in ISO ComplexPortal:CPX-1134 (PMID:23921129) RGD PMID:23921129 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Axin1 axin 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(MGI:3799599|PMID:17681137)
MGI:1856035 (MGI:3797993|PMID:18316368)		 UniProt
RGD		 PMID:17681137 PMID:18316368 GO_REF:0000024 MGI:3797993 MGI:3799599 NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 involved_in ISO (PMID:11865055) RGD PMID:11865055 NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606 		JBrowse link
G Card9 caspase recruitment domain family, member 9 acts_upstream_of_or_within ISO MGI:3698412 (MGI:3697751|PMID:17187069)
(PMID:17187069)		 RGD PMID:17187069 MGI:3697751 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (PMID:15778365) RGD PMID:15778365 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccl21 C-C motif chemokine ligand 21 involved_in ISO (PMID:15778365) RGD PMID:15778365 NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686 		JBrowse link
G Ccn2 cellular communication network factor 2 involved_in ISO (PMID:20008146) RGD PMID:20008146 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Cd27 CD27 molecule involved_in ISO (MGI:3687722|PMID:9692890) RGD PMID:9692890 MGI:3687722 NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592 		JBrowse link
G Cdc42 cell division cycle 42 IDA RGD PMID:17161586 RGD:2298583 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (MGI:2667426|PMID:12832451) RGD PMID:12832451 MGI:2667426 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Cracr2a calcium release activated channel regulator 2A involved_in ISO
IBA		 (PMID:27016526)
PMID:21873635
(MGI:6141997|PMID:27016526)		 RGD PMID:27016526 PMID:21873635 MGI:6141997, RGD:13792537 NCBI chr 4:160,428,987...160,517,427
Ensembl chr 4:160,408,077...160,518,107 		JBrowse link
G Crk CRK proto-oncogene, adaptor protein IMP RGD PMID:12198159 RGD:1298803 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406 		JBrowse link
G Dab2 DAB adaptor protein 2 involved_in ISO (MGI:5442512|PMID:15894542) RGD PMID:15894542 MGI:5442512 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:17389591), (PMID:19903888)		 UniProt
RGD		 PMID:17389591 PMID:19903888 GO_REF:0000024 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Dixdc1 DIX domain containing 1 IMP RGD PMID:19339625 RGD:2308917 NCBI chr 8:51,007,835...51,081,191
Ensembl chr 8:51,007,838...51,081,090 		JBrowse link
G Dusp19 dual specificity phosphatase 19 involved_in ISO (MGI:2182169|PMID:11959862) RGD PMID:11959862 MGI:2182169 NCBI chr 3:65,538,424...65,554,465
Ensembl chr 3:65,538,420...65,553,534 		JBrowse link
G Dusp22 dual specificity phosphatase 22 acts_upstream_of_or_within ISO (MGI:2387732|PMID:12138158) RGD PMID:12138158 MGI:2387732 NCBI chr17:33,780,980...33,831,540
Ensembl chr17:33,780,981...33,831,321 		JBrowse link
G Eda2r ectodysplasin A2 receptor involved_in IBA
ISO		 PMID:21873635
(PMID:12270937)		 RGD PMID:12270937 PMID:21873635 RGD:13792537 NCBI chr  X:62,224,763...62,269,344
Ensembl chr  X:62,228,229...62,269,268 		JBrowse link
G Edar ectodysplasin-A receptor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:26,587,836...26,666,543
Ensembl chr20:26,587,839...26,666,494 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:11413129) RGD PMID:11413129 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Fcgr2b Fc gamma receptor 2B involved_in ISO (MGI:5514474|PMID:23921129) RGD PMID:23921129 MGI:5514474 NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Fgd4 FYVE, RhoGEF and PH domain containing 4 IMP RGD PMID:9668039 RGD:1299389 NCBI chr11:84,399,885...84,551,013
Ensembl chr11:84,399,816...84,546,972 		JBrowse link
G Fgf19 fibroblast growth factor 19 involved_in ISO (PMID:12815072) RGD PMID:12815072 NCBI chr 1:200,056,656...200,059,944
Ensembl chr 1:200,056,644...200,060,287 		JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 involved_in ISO
IEA		 (PMID:16076871)
GO_REF:0000107		 RGD
Ensembl		 PMID:16076871 GO_REF:0000107 NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha involved_in ISO
IEA		 (PMID:9827804)
GO_REF:0000107		 RGD
Ensembl		 PMID:9827804 GO_REF:0000107 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta involved_in ISO (PMID:9827804) RGD PMID:9827804 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma involved_in ISO (PMID:9827804) RGD PMID:9827804 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:14678985) RGD PMID:14678985 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:12765338) RGD PMID:12765338 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565 		JBrowse link
G Hras HRas proto-oncogene, GTPase involved_in ISO (PMID:22065586) RGD PMID:22065586 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Il1a interleukin 1 alpha IDA RGD PMID:15671867 RGD:1358666 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta acts_upstream_of_or_within
involved_in		 IDA
ISO		 MGI:1346877 (MGI:3607973|PMID:16260493)
ComplexPortal:CPX-1134|UniProtKB:Q15109 (MGI:5902681|PMID:20739563)		 RGD PMID:16260493 PMID:20739563 PMID:15671867 MGI:3607973 MGI:5902681, RGD:1358666 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO (MGI:3032484|PMID:14967141) RGD PMID:14967141 MGI:3032484 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Ltbr lymphotoxin beta receptor involved_in ISO (PMID:20732415) RGD PMID:20732415 NCBI chr 4:158,108,884...158,115,339
Ensembl chr 4:158,108,886...158,121,539 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 IDA RGD PMID:17064355 RGD:2298577 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in IDA
ISO		 (MGI:1101248|PMID:9405446) RGD PMID:9405446 PMID:10051439 PMID:17064355 PMID:11849756 MGI:1101248, RGD:2298561, RGD:2298577, RGD:2298565 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IDA RGD PMID:9110999 RGD:2293488 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Map3k10 mitogen activated protein kinase kinase kinase 10 involved_in ISO (PMID:17584736) RGD PMID:17584736 NCBI chr 1:82,955,783...82,974,084
Ensembl chr 1:82,955,207...82,974,084 		JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 involved_in IDA
ISO		 (PMID:17584736) RGD PMID:17584736 PMID:17064355 RGD:2298577 NCBI chr 1:202,975,353...202,988,655
Ensembl chr 1:202,975,353...202,988,652 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in ISO (MGI:5616327|PMID:12050113) RGD PMID:12050113 MGI:5616327 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO MGI:104798|MGI:96536|MGI:96824 (MGI:3607973|PMID:16260493) RGD PMID:16260493 MGI:3607973 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Map4k2 mitogen activated protein kinase kinase kinase kinase 2 involved_in ISO (PMID:17584736) RGD PMID:17584736 NCBI chr 1:203,645,098...203,660,515
Ensembl chr 1:203,645,153...203,660,331 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 involved_in ISO (MGI:86683|PMID:9135144) RGD PMID:9135144 MGI:86683 NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5546548|PMID:23963642)		 UniProt
RGD		 PMID:23963642 GO_REF:0000024 MGI:5546548 NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884 		JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 involved_in IMP PMID:21076496 UniProt PMID:21076496 RGD:13673827 NCBI chr10:13,918,417...13,958,335
Ensembl chr10:13,918,400...13,958,273 		JBrowse link
G Mapkbp1 mitogen activated protein kinase binding protein 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:1344829|PMID:10471813)
PMID:21873635		 RGD PMID:10471813 PMID:21873635 MGI:1344829, RGD:13792537 NCBI chr 3:106,947,342...106,998,368
Ensembl chr 3:106,947,827...106,996,199 		JBrowse link
G Mbip MAP3K12 binding inhibitory protein 1 involved_in ISO (PMID:10801814), (PMID:32963352) RGD PMID:10801814 PMID:32963352 NCBI chr 6:73,808,133...73,825,394
Ensembl chr 6:73,808,133...73,825,374 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:28471450) RGD PMID:28471450 NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743 		JBrowse link
G Mink1 misshapen-like kinase 1 involved_in ISO
IEA		 (PMID:15469942)
(MGI:1354211|PMID:10708748)
GO_REF:0000107		 RGD
Ensembl		 PMID:10708748 PMID:15469942 GO_REF:0000107 MGI:1354211 NCBI chr10:55,278,293...55,330,782
Ensembl chr10:55,278,391...55,330,782 		JBrowse link
G Mmp8 matrix metallopeptidase 8 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6201889|PMID:25049354)		 Ensembl
RGD		 PMID:25049354 GO_REF:0000107 MGI:6201889 NCBI chr 8:4,724,009...4,732,956
Ensembl chr 8:4,724,029...4,733,520 		JBrowse link
G Mturn maturin, neural progenitor differentiation regulator homolog involved_in ISO (PMID:24681962) RGD PMID:24681962 NCBI chr 4:83,807,528...83,828,494
Ensembl chr 4:83,807,579...83,824,950 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within ISO MGI:2385681 (MGI:2669022|PMID:12855817) RGD PMID:12855817 MGI:2669022 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 involved_in ISO (PMID:11865055) RGD PMID:11865055 NCBI chr 2:31,507,423...31,559,098
Ensembl chr 2:31,507,424...31,570,542 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 involved_in ISO (PMID:26514923) RGD PMID:26514923 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (MGI:3775161|PMID:18261938) RGD PMID:18261938 MGI:3775161 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (MGI:3775161|PMID:18261938)
(PMID:17187069)		 RGD PMID:17187069 PMID:18261938 MGI:3775161 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Nox1 NADPH oxidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3616995 (MGI:4881403|PMID:19661248)		 Ensembl
RGD		 PMID:19661248 GO_REF:0000107 MGI:4881403 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nrk Nik related kinase acts_upstream_of_or_within ISO (MGI:1860727|PMID:10801798) RGD PMID:10801798 MGI:1860727 NCBI chr  X:102,365,747...102,462,957
Ensembl chr  X:102,365,765...102,459,657 		JBrowse link
G Pja2 praja ring finger ubiquitin ligase 2 involved_in ISO
ISS		 (PMID:28471450)
GO_REF:0000024		 RGD
UniProt		 PMID:28471450 GO_REF:0000024 NCBI chr 9:103,956,678...104,006,763
Ensembl chr 9:103,956,678...104,006,783 		JBrowse link
G Plcb1 phospholipase C beta 1 involved_in ISO
IEA		 (PMID:9500449)
GO_REF:0000107		 RGD
Ensembl		 PMID:9500449 GO_REF:0000107 NCBI chr 3:122,059,968...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISS
ISO		 GO_REF:0000024
(PMID:8670418)		 UniProt
RGD		 PMID:8670418 GO_REF:0000024 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:21487011) RGD PMID:21487011 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in ISO (PMID:19933860) RGD PMID:19933860 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056 		JBrowse link
G Rassf2 Ras association domain family member 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:19962960)		 RGD PMID:19962960 PMID:21873635 RGD:13792537 NCBI chr 3:119,244,288...119,280,462
Ensembl chr 3:119,245,821...119,280,431 		JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 acts_upstream_of_or_within ISO MGI:104798 (MGI:3689241|PMID:17015619) RGD PMID:17015619 MGI:3689241 NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (PMID:17389591)
(MGI:5306563|PMID:20125124)		 RGD PMID:17389591 PMID:20125124 MGI:5306563 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2446070|MGI:2660793 (MGI:2176422|PMID:11894098), (MGI:2176424|PMID:11894097), (MGI:3775161|PMID:18261938) RGD PMID:11894097 PMID:11894098 PMID:18261938 MGI:2176422 MGI:2176424 MGI:3775161 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Serpinf2 serpin family F member 2 involved_in ISO (PMID:20008146) RGD PMID:20008146 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243 		JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(MGI:5546548|PMID:23963642), (MGI:6158776|PMID:27084103)		 UniProt
RGD		 PMID:23963642 PMID:27084103 PMID:21873635 GO_REF:0000024 MGI:5546548 MGI:6158776, RGD:13792537 NCBI chr16:28,735,522...28,901,690
Ensembl chr16:28,735,440...28,901,644 		JBrowse link
G Sh3rf2 SH3 domain containing ring finger 2 involved_in ISO
IBA
ISS		 (PMID:24130170)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:24130170 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr18:34,045,715...34,148,342
Ensembl chr18:34,046,879...34,146,856 		JBrowse link
G Sh3rf3 SH3 domain containing ring finger 3 involved_in ISO
IBA		 (PMID:20696164)
PMID:21873635		 RGD PMID:20696164 PMID:21873635 RGD:13792537 NCBI chr20:26,765,278...27,099,261
Ensembl chr20:26,765,015...27,099,257 		JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (PMID:20231852) RGD PMID:20231852 NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497 		JBrowse link
G Stk3 serine/threonine kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:104798|MGI:1929004 (MGI:4420852|PMID:20080598)		 Ensembl
RGD		 PMID:20080598 GO_REF:0000107 MGI:4420852 NCBI chr 7:66,053,209...66,323,292
Ensembl chr 7:66,052,345...66,323,233 		JBrowse link
G Taok1 TAO kinase 1 involved_in ISO
IEA
ISS		 (PMID:16407310)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:16407310 GO_REF:0000024 GO_REF:0000107 NCBI chr10:62,373,076...62,465,295
Ensembl chr10:62,381,404...62,465,766 		JBrowse link
G Taok2 TAO kinase 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5462161|PMID:22683681)
(PMID:10660600)		 Ensembl
RGD		 PMID:10660600 PMID:22683681 GO_REF:0000107 MGI:5462161 NCBI chr 1:181,475,708...181,494,738
Ensembl chr 1:181,475,711...181,494,613 		JBrowse link
G Taok3 TAO kinase 3 involved_in ISO
IEA		 (PMID:10924369)
GO_REF:0000107		 RGD
Ensembl		 PMID:10924369 GO_REF:0000107 NCBI chr12:39,314,027...39,394,243
Ensembl chr12:39,314,027...39,461,244 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:11544529) RGD PMID:11544529 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of_or_within ISO (MGI:3607973|PMID:16260493) RGD PMID:16260493 MGI:3607973 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1346877 (MGI:3607973|PMID:16260493), (MGI:3775161|PMID:18261938)		 Ensembl
RGD		 PMID:16260493 PMID:18261938 GO_REF:0000107 MGI:3607973 MGI:3775161 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO MGI:1346877 (MGI:3607973|PMID:16260493), (MGI:4420852|PMID:20080598) RGD PMID:16260493 PMID:20080598 MGI:3607973 MGI:4420852 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf19 TNF receptor superfamily member 19 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:35,092,206...35,158,472
Ensembl chr15:35,092,206...35,180,795 		JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:109520 (MGI:5308511|PMID:22073305)
GO_REF:0000107		 RGD
Ensembl		 PMID:22073305 GO_REF:0000107 MGI:5308511 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tnik TRAF2 and NCK interacting kinase involved_in ISO (PMID:10521462), (PMID:15342639) RGD PMID:10521462 PMID:15342639 NCBI chr 2:111,184,352...111,587,993
Ensembl chr 2:111,184,387...111,580,750 		JBrowse link
G Tpd52l1 TPD52 like 1 involved_in ISO (PMID:14761963) RGD PMID:14761963 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109 		JBrowse link
G Traf1 TNF receptor-associated factor 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Traf3 Tnf receptor-associated factor 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:130,199,696...130,307,168
Ensembl chr 6:130,206,484...130,305,481 		JBrowse link
G Traf4 Tnf receptor associated factor 4 involved_in IBA
ISO		 PMID:21873635
(PMID:16157600)		 RGD PMID:16157600 PMID:21873635 RGD:13792537 NCBI chr10:63,054,169...63,060,284
Ensembl chr10:63,054,181...63,060,284 		JBrowse link
G Traf5 TNF receptor-associated factor 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:103,569,944...103,618,756
Ensembl chr13:103,572,314...103,618,709 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in ISO (MGI:5440106|PMID:23021218) RGD PMID:23021218 MGI:5440106 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
G Unc5cl unc-5 family C-terminal like involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:22158417)		 RGD PMID:22158417 PMID:21873635 RGD:13792537 NCBI chr 9:12,528,109...12,543,382
Ensembl chr 9:12,528,246...12,542,233 		JBrowse link
G Wnt16 Wnt family member 16 involved_in ISO (PMID:17200136) RGD PMID:17200136 NCBI chr 4:50,820,968...50,831,380
Ensembl chr 4:50,820,968...50,831,380 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of ISO (MGI:4820702|PMID:20032469) RGD PMID:20032469 MGI:4820702 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Wnt7a Wnt family member 7A involved_in IMP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:18567805 PMID:21873635 RGD:4107045, RGD:13792537 NCBI chr 4:123,863,108...123,908,981
Ensembl chr 4:123,863,108...123,908,981 		JBrowse link
G Wnt7b Wnt family member 7B involved_in IDA
IBA
IMP		 PMID:21873635 RGD
GO_Central		 PMID:18177422 PMID:21873635 PMID:18177422 RGD:2292645, RGD:13792537, RGD:2292645 NCBI chr 7:116,634,817...116,679,089
Ensembl chr 7:116,634,814...116,679,581 		JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in ISO (PMID:11865055) RGD PMID:11865055 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
G Zfp622 zinc finger protein 622 involved_in ISO (PMID:21771788) RGD PMID:21771788 NCBI chr 2:76,479,605...76,494,405
Ensembl chr 2:76,335,609...76,493,898 		JBrowse link
positive regulation of p38MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in ISO ComplexPortal:CPX-1134|UniProtKB:P10749 (PMID:20739563) RGD PMID:20739563 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:23389627) RGD PMID:23389627 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:22540193)		 Ensembl
RGD		 PMID:22540193 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in ISO
IEA		 (PMID:17600318)
GO_REF:0000107		 RGD
Ensembl		 PMID:17600318 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 IDA RGD PMID:18584881 RGD:2303073 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Emc10 ER membrane protein complex subunit 10 involved_in ISO (MGI:6163930|PMID:28931551) RGD PMID:28931551 MGI:6163930 NCBI chr 1:94,980,260...94,988,847
Ensembl chr 1:94,943,587...94,988,847 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha involved_in ISO
IEA		 (PMID:9827804)
GO_REF:0000107		 RGD
Ensembl		 PMID:9827804 GO_REF:0000107 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta involved_in ISO (PMID:9827804) RGD PMID:9827804 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma involved_in ISO (PMID:9827804) RGD PMID:9827804 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610 		JBrowse link
G Gdf6 growth differentiation factor 6 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5751611|PMID:26774823)		 UniProt
RGD		 PMID:26774823 GO_REF:0000024 MGI:5751611 NCBI chr 5:22,996,246...23,012,567
Ensembl chr 5:22,996,246...23,012,567 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:24161931)		 Ensembl
RGD		 PMID:24161931 GO_REF:0000107 NCBI chr16:32,917,826...32,919,880
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO ComplexPortal:CPX-1134|UniProtKB:Q15109 (MGI:5902681|PMID:20739563) RGD PMID:20739563 MGI:5902681 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Lep leptin involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(PMID:24340098)		 UniProt
RGD		 PMID:24340098 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 acts_upstream_of_or_within ISO (MGI:1353859|PMID:10700190) RGD PMID:10700190 MGI:1353859 NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848 		JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 involved_in ISO (PMID:9305639) RGD PMID:9305639 NCBI chr 1:48,431,801...48,519,358
Ensembl chr 1:48,431,830...48,519,358 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 IMP RGD PMID:20716917 RGD:10412640 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:3041135 (MGI:5529574|PMID:23994610) RGD PMID:23994610 MGI:5529574 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:28471450) RGD PMID:28471450 NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743 		JBrowse link
G Mink1 misshapen-like kinase 1 involved_in ISO (MGI:1354211|PMID:10708748) RGD PMID:10708748 MGI:1354211 NCBI chr10:55,278,293...55,330,782
Ensembl chr10:55,278,391...55,330,782 		JBrowse link
G Mir181a2 microRNA 181a-2 involved_in ISO (PMID:23993976) RGD PMID:23993976 NCBI chr 3:22,615,845...22,615,961
Ensembl chr 3:22,615,845...22,615,961 		JBrowse link
G Mir181b1 microRNA 181b-1 involved_in ISO (PMID:23993976) RGD PMID:23993976 NCBI chr13:49,485,688...49,485,797
Ensembl chr13:49,485,688...49,485,797 		JBrowse link
G Mir181b2 microRNA 181b-2 involved_in ISO (PMID:23993976) RGD PMID:23993976 NCBI chr 3:22,616,948...22,617,035
Ensembl chr 3:22,616,948...22,617,035 		JBrowse link
G Mir181d microRNA 181d involved_in ISO (PMID:23993976) RGD PMID:23993976 NCBI chr19:23,983,706...23,983,788
Ensembl chr19:23,983,706...23,983,788 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 involved_in ISO (PMID:26514923) RGD PMID:26514923 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Oprk1 opioid receptor, kappa 1 IDA RGD PMID:16648139 RGD:9831415 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Pja2 praja ring finger ubiquitin ligase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:28471450)		 UniProt
RGD		 PMID:28471450 GO_REF:0000024 NCBI chr 9:103,956,678...104,006,763
Ensembl chr 9:103,956,678...104,006,783 		JBrowse link
G Prmt1 protein arginine methyltransferase 1 involved_in IDA PMID:23483889 BHF-UCL PMID:23483889 RGD:10047341 NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345 		JBrowse link
G Rell1 RELT-like 1 involved_in IBA
ISO		 PMID:21873635
(PMID:28688764)		 RGD PMID:28688764 PMID:21873635 RGD:13792537 NCBI chr14:44,318,640...44,378,541
Ensembl chr14:44,303,009...44,378,500 		JBrowse link
G Rell2 RELT-like 2 involved_in IBA
IEA
ISO
ISS		 PMID:21873635
GO_REF:0000002
(PMID:28688764)
GO_REF:0000024		 InterPro
RGD
UniProt		 PMID:28688764 PMID:21873635 GO_REF:0000002 GO_REF:0000024, RGD:13792537 NCBI chr18:29,789,996...29,793,986
Ensembl chr18:29,790,415...29,793,986 		JBrowse link
G Sash1 SAM and SH3 domain containing 1 acts_upstream_of_or_within ISO (PMID:23776175) RGD PMID:23776175 NCBI chr 1:3,119,915...3,418,536
Ensembl chr 1:3,121,332...3,439,870 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23935096)		 UniProt
Ensembl
RGD		 PMID:23935096 GO_REF:0000024 GO_REF:0000107 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (MGI:6478061|PMID:28912174) RGD PMID:28912174 MGI:6478061 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
G Stk39 serine threonine kinase 39 involved_in ISO
IMP		 (PMID:10980603) RGD PMID:10980603 PMID:10980603 RGD:727300 NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (PMID:18386220) RGD PMID:18386220 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Xdh xanthine dehydrogenase involved_in ISO
IEA		 (PMID:18386220)
GO_REF:0000107		 RGD
Ensembl		 PMID:18386220 GO_REF:0000107 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISO (PMID:24048733) RGD PMID:24048733 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
positive regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18387645)		 Ensembl
RGD		 PMID:18387645 GO_REF:0000107 NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608 		JBrowse link
G Card9 caspase recruitment domain family, member 9 acts_upstream_of_or_within
involved_in		 ISO
ISS		 MGI:3698412 (MGI:3697751|PMID:17187069)
(MGI:6117948|PMID:29080677)
(PMID:17187069)
GO_REF:0000024		 RGD
UniProt		 PMID:17187069 PMID:29080677 GO_REF:0000024 MGI:3697751 MGI:6117948 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:19211730 RGD:5130956 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5487533|PMID:20038207)		 UniProt
RGD		 PMID:20038207 GO_REF:0000024 MGI:5487533 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:17161379 RGD:5508698 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 involved_in ISO (PMID:24003225) RGD PMID:24003225 NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966 		JBrowse link
G Il1a interleukin 1 alpha IDA RGD PMID:15671867 RGD:1358666 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta IMP
IDA		 RGD PMID:12629164 PMID:15671867 RGD:1626685, RGD:1358666 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) RGD PMID:28436939 NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729 		JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor NOT IMP RGD PMID:16222076 RGD:1599289 NCBI chr13:44,774,823...44,780,707
Ensembl chr13:44,774,823...44,780,612 		JBrowse link
G Klhdc10 kelch domain containing 10 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:59,021,300...59,079,118
Ensembl chr 4:59,021,310...59,074,941 		JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 IMP RGD PMID:12024021 RGD:2302280 NCBI chr 7:120,526,732...120,536,982
Ensembl chr 7:120,526,732...120,536,982 		JBrowse link
G Mid1 midline 1 involved_in ISO (PMID:17438131) RGD PMID:17438131 NCBI chr  X:24,116,674...24,491,205
Ensembl chr  X:24,120,293...24,248,353 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (MGI:3775161|PMID:18261938) RGD PMID:18261938 MGI:3775161 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (MGI:3775161|PMID:18261938)
(PMID:17187069)		 RGD PMID:17187069 PMID:18261938 MGI:3775161 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Pdcd10 programmed cell death 10 involved_in ISO (PMID:22652780) RGD PMID:22652780 NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2446070|MGI:2660793 (MGI:2176422|PMID:11894098), (MGI:2176424|PMID:11894097), (MGI:3775161|PMID:18261938) RGD PMID:11894097 PMID:11894098 PMID:18261938 MGI:2176422 MGI:2176424 MGI:3775161 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (MGI:5803730|PMID:27288407) RGD PMID:27288407 MGI:5803730 NCBI chr10:55,507,593...55,528,288
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
G Sema4c semaphorin 4C involved_in ISO (PMID:17498836) RGD PMID:17498836 NCBI chr 9:38,791,668...38,802,171
Ensembl chr 9:38,791,670...38,802,128 		JBrowse link
G Stk25 serine/threonine kinase 25 involved_in ISO (PMID:22652780) RGD PMID:22652780 NCBI chr 9:94,161,834...94,174,095
Ensembl chr 9:94,161,836...94,174,244 		JBrowse link
G Taok1 TAO kinase 1 involved_in ISO
ISS		 (PMID:17396146)
GO_REF:0000024		 RGD
UniProt		 PMID:17396146 GO_REF:0000024 NCBI chr10:62,373,076...62,465,295
Ensembl chr10:62,381,404...62,465,766 		JBrowse link
G Taok2 TAO kinase 2 involved_in ISO
ISS		 (PMID:17396146)
GO_REF:0000024		 RGD
UniProt		 PMID:17396146 GO_REF:0000024 NCBI chr 1:181,475,708...181,494,738
Ensembl chr 1:181,475,711...181,494,613 		JBrowse link
G Taok3 TAO kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17396146)		 UniProt
RGD		 PMID:17396146 GO_REF:0000024 NCBI chr12:39,314,027...39,394,243
Ensembl chr12:39,314,027...39,461,244 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17192487)		 UniProt
RGD		 PMID:17192487 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of_or_within ISO (MGI:3775161|PMID:18261938) RGD PMID:18261938 MGI:3775161 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
positive regulation of stress-activated protein kinase signaling cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:10891478) RGD PMID:10891478 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Rnf13 ring finger protein 13 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23378536)		 UniProt
RGD		 PMID:23378536 GO_REF:0000024 NCBI chr 2:141,927,887...142,061,801
Ensembl chr 2:141,927,909...142,061,801 		JBrowse link
regulation of JNK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cops5 COP9 signalosome subunit 5 involved_in ISO (PMID:16410250) RGD PMID:16410250 NCBI chr 5:9,192,233...9,210,498
Ensembl chr 5:9,192,100...9,210,731 		JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:26514923) RGD PMID:26514923 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Ephb1 Eph receptor B1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:9430661)		 UniProt
RGD		 PMID:9430661 GO_REF:0000024 NCBI chr 8:102,507,549...102,944,839
Ensembl chr 8:102,507,549...102,944,839 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
ISS		 (PMID:16410250)
GO_REF:0000024		 RGD
UniProt		 PMID:16410250 GO_REF:0000024 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 involved_in IMP PMID:11152698 UniProt PMID:11152698 RGD:8554109 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor involved_in ISO
ISS
IEA
IBA		 (PMID:12556535)
GO_REF:0000024
GO_REF:0000107
PMID:21873635		 RGD
UniProt
Ensembl		 PMID:12556535 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Magi3 membrane associated guanylate kinase, WW and PDZ domain containing 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:191,514,726...191,717,048
Ensembl chr 2:191,518,506...191,716,735 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 involved_in ISO (PMID:14966141) RGD PMID:14966141 NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:2182167|PMID:11562351)
PMID:21873635		 UniProt
RGD		 PMID:11562351 PMID:21873635 GO_REF:0000024 MGI:2182167, RGD:13792537 NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884 		JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 involved_in IBA
ISO		 PMID:21873635
(PMID:10490659)		 RGD PMID:10490659 PMID:21873635 RGD:13792537 NCBI chr 7:120,526,732...120,536,982
Ensembl chr 7:120,526,732...120,536,982 		JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 involved_in ISO (MGI:1352260|PMID:10629060) RGD PMID:10629060 MGI:1352260 NCBI chr10:13,918,417...13,958,335
Ensembl chr10:13,918,400...13,958,273 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IMP RGD PMID:17348686 RGD:2298766 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mdfi MyoD family inhibitor involved_in ISO (MGI:4441137|PMID:12192039) RGD PMID:12192039 MGI:4441137 NCBI chr 9:13,156,806...13,175,218
Ensembl chr 9:13,156,866...13,175,217 		JBrowse link
G Mdfic MyoD family inhibitor domain containing involved_in ISO (PMID:12192039) RGD PMID:12192039 NCBI chr 4:43,972,310...44,052,162
Ensembl chr 4:43,972,507...44,052,161 		JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:17386267)		 Ensembl
RGD		 PMID:17386267 GO_REF:0000107 NCBI chr13:22,308,532...22,530,978
Ensembl chr13:22,308,548...22,530,977 		JBrowse link
G Rap2a RAP2A, member of RAS oncogene family involved_in ISO (PMID:14966141) RGD PMID:14966141 NCBI chr15:97,596,848...97,597,338
Ensembl chr15:97,596,020...97,624,138 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 IMP RGD PMID:10811109 RGD:11534984 NCBI chr 3:12,898,349...13,016,234
Ensembl chr 3:12,898,266...13,013,984 		JBrowse link
G Sh3rf2 SH3 domain containing ring finger 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:34,045,715...34,148,342
Ensembl chr18:34,046,879...34,146,856 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 NOT|involved_in ISO (MGI:2663364|PMID:12773577) RGD PMID:12773577 MGI:2663364 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 acts_upstream_of_or_within ISO (MGI:2680840|PMID:12958312) RGD PMID:12958312 MGI:2680840 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Ulk4 unc-51 like kinase 4 acts_upstream_of_or_within ISO (PMID:24284070) RGD PMID:24284070 NCBI chr 8:120,670,879...120,966,026
Ensembl chr 8:120,670,866...120,966,924 		JBrowse link
G Zfp110 zinc finger protein 110 involved_in ISO (MGI:3579762|PMID:15668238) RGD PMID:15668238 MGI:3579762 NCBI chr 1:73,445,303...73,461,112
Ensembl chr 1:73,445,336...73,461,086 		JBrowse link
regulation of p38MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in ISO
IBA		 ComplexPortal:CPX-1134 (MGI:6094326|PMID:18367618)
PMID:21873635		 RGD PMID:18367618 PMID:21873635 MGI:6094326, RGD:13792537 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Cav3 caveolin 3 acts_upstream_of_or_within ISO (MGI:4946902|PMID:21182936) RGD PMID:21182936 MGI:4946902 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:4453088|PMID:19948740)		 UniProt
RGD		 PMID:19948740 GO_REF:0000024 MGI:4453088 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Hgf hepatocyte growth factor acts_upstream_of_or_within ISO (MGI:5529574|PMID:23994610) RGD PMID:23994610 MGI:5529574 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Lgals9 galectin 9 NOT|involved_in ISO (PMID:24465902) RGD PMID:24465902 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Per1 period circadian regulator 1 involved_in IMP PMID:24447840 UniProt PMID:24447840 RGD:8655527 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431 		JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 involved_in ISO
IEA		 (PMID:17386267)
GO_REF:0000107		 RGD
Ensembl		 PMID:17386267 GO_REF:0000107 NCBI chr13:22,308,532...22,530,978
Ensembl chr13:22,308,548...22,530,977 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 NOT|involved_in ISO (PMID:19933860) RGD PMID:19933860 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 NOT|involved_in ISO (MGI:5440106|PMID:23021218) RGD PMID:23021218 MGI:5440106 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
G Ulk4 unc-51 like kinase 4 acts_upstream_of_or_within ISO (PMID:24284070) RGD PMID:24284070 NCBI chr 8:120,670,879...120,966,026
Ensembl chr 8:120,670,866...120,966,924 		JBrowse link
regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000067941 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr11:42,352,734...42,354,134 JBrowse link
G Fas Fas cell surface death receptor involved_in IBA
ISO		 PMID:21873635
(PMID:11096076)		 RGD PMID:11096076 PMID:21873635 RGD:13792537 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist NOT|involved_in ISO (MGI:5318033|PMID:12135612) RGD PMID:12135612 MGI:5318033 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5009198|PMID:10945608)		 BHF-UCL
RGD		 PMID:10945608 GO_REF:0000024 MGI:5009198 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in TAS PMID:19565474 UniProt PMID:19565474 RGD:8553538 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 involved_in TAS PMID:19565474 UniProt PMID:19565474 RGD:8553538 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in TAS
IEA		 PMID:19565474
GO_REF:0000117		 UniProt PMID:19565474 GO_REF:0000117, RGD:8553538 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in TAS PMID:19565474 UniProt PMID:19565474 RGD:8553538 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Nbr1 NBR1, autophagy cargo receptor involved_in IEA
ISO		 GO_REF:0000107
(MGI:4818844|PMID:20616007)		 Ensembl
RGD		 PMID:20616007 GO_REF:0000107 MGI:4818844 NCBI chr10:86,477,775...86,506,418
Ensembl chr10:86,478,290...86,506,412 		JBrowse link
G Prdx1 peroxiredoxin 1 acts_upstream_of_or_within ISO (MGI:3695235|PMID:16880205) RGD PMID:16880205 MGI:3695235 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
regulation of stress-activated protein kinase signaling cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033 (MGI:3789238|PMID:16079796) RGD PMID:16079796 MGI:3789238 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110 		JBrowse link
stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen IDA RGD PMID:21367774 RGD:5129174 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Card9 caspase recruitment domain family, member 9 acts_upstream_of ISO MGI:3698412 (MGI:3697751|PMID:17187069) RGD PMID:17187069 MGI:3697751 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Cryab crystallin, alpha B IMP RGD PMID:18420382 RGD:2303631 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157 		JBrowse link
G Dusp10 dual specificity phosphatase 10 acts_upstream_of ISO MGI:3052343 (MGI:4366202|PMID:19696743) RGD PMID:19696743 MGI:4366202 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 involved_in ISO (PMID:8663524), (PMID:9218798) RGD PMID:8663524 PMID:9218798 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in IDA
IBA
ISO		 PMID:10051439
PMID:21873635
(PMID:9535930)		 RGD PMID:9535930 PMID:10051439 PMID:21873635 RGD:2298561, RGD:13792537 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 involved_in ISO (PMID:11726277) RGD PMID:11726277 NCBI chr11:79,094,087...79,235,181
Ensembl chr11:79,097,247...79,235,181 		JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:11836244) RGD PMID:11836244 NCBI chr 3:57,128,561...57,289,943
Ensembl chr 3:57,130,551...57,289,626 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO (PMID:9079627) RGD PMID:9079627 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk11 mitogen-activated protein kinase 11 involved_in ISO (PMID:8663524) RGD PMID:8663524 NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395 		JBrowse link
G Mapk13 mitogen activated protein kinase 13 involved_in ISO
IEA
ISS		 (PMID:9218798)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:9218798 GO_REF:0000024 GO_REF:0000107 NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 IDA RGD PMID:16407200 RGD:1580544 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of ISO (MGI:3775161|PMID:18261938) RGD PMID:18261938 MGI:3775161 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of ISO (MGI:3775161|PMID:18261938) RGD PMID:18261938 MGI:3775161 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Pbk PDZ binding kinase acts_upstream_of ISO MGI:5293435 (MGI:5293269|PMID:21715333) RGD PMID:21715333 MGI:5293269 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of ISO MGI:2446070|MGI:2660793 (MGI:2176422|PMID:11894098), (MGI:2176424|PMID:11894097), (MGI:3775161|PMID:18261938) RGD PMID:11894097 PMID:11894098 PMID:18261938 MGI:2176422 MGI:2176424 MGI:3775161 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Taok2 TAO kinase 2 involved_in ISO
ISS
IEA		 (PMID:11279118)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:11279118 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:181,475,708...181,494,738
Ensembl chr 1:181,475,711...181,494,613 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of ISO (MGI:3775161|PMID:18261938) RGD PMID:18261938 MGI:3775161 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20094
    response to stimulus 10534
      response to stress 4245
        cellular response to stress 2126
          stress-activated protein kinase signaling cascade 266
            negative regulation of stress-activated protein kinase signaling cascade + 54
            positive regulation of stress-activated protein kinase signaling cascade + 143
            regulation of stress-activated protein kinase signaling cascade + 218
            stress-activated MAPK cascade + 257
Path 2
Term Annotations click to browse term
  biological_process 20094
    biological regulation 13926
      regulation of biological process 13157
        regulation of cellular process 12435
          signal transduction 7105
            intracellular signal transduction 2740
              stress-activated protein kinase signaling cascade 266
                negative regulation of stress-activated protein kinase signaling cascade + 54
                positive regulation of stress-activated protein kinase signaling cascade + 143
                regulation of stress-activated protein kinase signaling cascade + 218
                stress-activated MAPK cascade + 257
paths to the root