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ONTOLOGY REPORT - ANNOTATIONS


Term:nuclear-transcribed mRNA catabolic process, deadenylation-independent decay
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Accession:GO:0031086 term browser browse the term
Definition:A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability.
Synonyms:exact_synonym: deadenylation-independent mRNA decay;   deadenylylation-independent mRNA decay;   mRNA breakdown, deadenylation-independent decay;   mRNA catabolic process, deadenylation-independent;   mRNA catabolic process, deadenylylation-independent;   mRNA catabolism, deadenylation-independent;   mRNA catabolism, deadenylation-independent decay;   mRNA catabolism, deadenylylation-independent;   mRNA degradation, deadenylation-independent decay;   nuclear mRNA catabolic process, deadenylation-independent decay


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nuclear-transcribed mRNA catabolic process, deadenylation-independent decay term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zfp36 zinc finger protein 36 ISO
ISS
(PMID:11279239)
GO_REF:0000024
RGD
UniProt
PMID:11279239 GO_REF:0000024 NCBI chr 1:85,380,088...85,382,565
Ensembl chr 1:85,380,088...85,382,569
JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 IDA PMID:11279239 UniProt PMID:11279239 RGD:11344953 NCBI chr 6:103,308,032...103,313,074
Ensembl chr 6:103,308,045...103,313,074
JBrowse link
deadenylation-independent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dcp1a decapping mRNA 1A IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:6,542,415...6,583,856
Ensembl chr16:6,542,216...6,587,619
JBrowse link
G Dcp1b decapping mRNA 1B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:151,249,654...151,287,018
Ensembl chr 4:151,250,041...151,285,702
JBrowse link
G Edc3 enhancer of mRNA decapping 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:62,482,126...62,527,665
Ensembl chr 8:62,482,140...62,526,202
JBrowse link
G Edc4 enhancer of mRNA decapping 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:37,852,659...37,864,651
Ensembl chr19:37,852,659...37,866,355
JBrowse link
positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zfp36 zinc finger protein 36 ISO
ISS
(PMID:16364915)
GO_REF:0000024
RGD
UniProt
PMID:16364915 GO_REF:0000024 NCBI chr 1:85,380,088...85,382,565
Ensembl chr 1:85,380,088...85,382,569
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      negative regulation of metabolic process 3311
        negative regulation of macromolecule metabolic process 3047
          negative regulation of gene expression 2169
            mRNA catabolic process 231
              nuclear-transcribed mRNA catabolic process 116
                nuclear-transcribed mRNA catabolic process, deadenylation-independent decay 6
                  deadenylation-independent decapping of nuclear-transcribed mRNA + 5
                  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-independent decay + 0
Path 2
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      cellular metabolic process 11085
        cellular aromatic compound metabolic process 5715
          nucleobase-containing compound metabolic process 5489
            nucleic acid metabolic process 4985
              RNA metabolic process 4469
                RNA catabolic process 267
                  mRNA catabolic process 231
                    nuclear-transcribed mRNA catabolic process 116
                      nuclear-transcribed mRNA catabolic process, deadenylation-independent decay 6
                        deadenylation-independent decapping of nuclear-transcribed mRNA + 5
                        exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-independent decay + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.