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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of histone methylation
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Accession:GO:0031061 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones.
Synonyms:exact_synonym: down regulation of histone methylation;   downregulation of histone methylation
 narrow_synonym: inhibition of histone methylation



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negative regulation of histone methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fendrr FOXF1 adjacent non-coding developmental regulatory RNA acts_upstream_of_or_within ISO MGI:5470087 (MGI:5462100|PMID:23369715) RGD PMID:23369715 MGI:5462100 NCBI chr19:49,127,225...49,152,779
Ensembl chr19:49,121,214...49,153,240
JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 involved_in ISO (MGI:4431292|PMID:20064375), (MGI:4436818|PMID:20064376) RGD PMID:20064375 PMID:20064376 MGI:4431292 MGI:4436818 NCBI chr17:19,777,487...19,957,696
Ensembl chr17:19,777,266...19,955,690
JBrowse link
negative regulation of histone H3-K27 methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ezhip EZH inhibitory protein involved_in ISO (PMID:29909548), (PMID:30923826) RGD PMID:29909548 PMID:30923826 NCBI chr  X:16,368,582...16,373,642
Ensembl chr  X:16,368,962...16,372,256
JBrowse link
G Macroh2a1 macroH2A.1 histone involved_in ISO (PMID:25526730) RGD PMID:25526730 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072
JBrowse link
G Mtf2 metal response element binding transcription factor 2 involved_in ISO (MGI:4946172|PMID:21059868) RGD PMID:21059868 MGI:4946172 NCBI chr14:1,639,256...1,683,513
Ensembl chr14:1,640,746...1,683,524
JBrowse link
G Phf1 PHD finger protein 1 involved_in ISO (PMID:23142980) RGD PMID:23142980 NCBI chr20:5,017,765...5,022,872
Ensembl chr20:5,017,893...5,022,871
JBrowse link
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor involved_in ISO (PMID:23503590)
(MGI:5484727|PMID:23503590)
RGD PMID:23503590 MGI:5484727 NCBI chr10:63,103,920...63,140,780
Ensembl chr10:63,103,921...63,140,780
JBrowse link
negative regulation of histone H3-K27 trimethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ezhip EZH inhibitory protein acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:6404408 (MGI:6362099|PMID:31451685)
PMID:21873635
RGD PMID:31451685 PMID:21873635 MGI:6362099, RGD:13792537 NCBI chr  X:16,368,582...16,373,642
Ensembl chr  X:16,368,962...16,372,256
JBrowse link
negative regulation of histone H3-K36 methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcor BCL6 co-repressor involved_in ISO (PMID:19578371) RGD PMID:19578371 NCBI chr  X:10,609,756...10,729,613
Ensembl chr  X:10,687,732...10,729,613
JBrowse link
G Fh fumarate hydratase involved_in ISO
ISS
(PMID:26237645)
GO_REF:0000024
RGD
UniProt
PMID:26237645 GO_REF:0000024 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
JBrowse link
negative regulation of histone H3-K4 methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcor BCL6 co-repressor involved_in ISO (PMID:19578371) RGD PMID:19578371 NCBI chr  X:10,609,756...10,729,613
Ensembl chr  X:10,687,732...10,729,613
JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in IEA
ISO
GO_REF:0000107
(MGI:5009779|PMID:20820192)
Ensembl
RGD
PMID:20820192 GO_REF:0000107 MGI:5009779 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Gfi1b growth factor independent 1B transcriptional repressor involved_in ISO (MGI:5284774|PMID:17707228) RGD PMID:17707228 MGI:5284774 NCBI chr 3:11,940,232...11,952,989
Ensembl chr 3:11,940,233...11,952,942
JBrowse link
G Kdm1a lysine demethylase 1A involved_in ISO (MGI:4461095|PMID:20123967) RGD PMID:20123967 MGI:4461095 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Macroh2a1 macroH2A.1 histone involved_in ISO (PMID:25526730) RGD PMID:25526730 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072
JBrowse link
G Prmt6 protein arginine methyltransferase 6 acts_upstream_of_or_within ISO (MGI:5504576|PMID:22904064) RGD PMID:22904064 MGI:5504576 NCBI chr 2:197,927,750...197,932,980
Ensembl chr 2:197,927,220...197,933,648
JBrowse link
G Wdr5 WD repeat domain 5 involved_in ISO (PMID:26324722) RGD PMID:26324722 NCBI chr 3:10,836,964...10,856,682
Ensembl chr 3:10,837,025...10,856,671
JBrowse link
negative regulation of histone H3-K79 methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mllt6 MLLT6, PHD finger containing acts_upstream_of_or_within ISO MGI:3856248 (MGI:5644399|PMID:21546577) RGD PMID:21546577 MGI:5644399 NCBI chr10:82,657,258...82,678,899
Ensembl chr10:82,656,872...82,676,073
JBrowse link
negative regulation of histone H3-K9 dimethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pih1d1 PIH1 domain containing 1 involved_in ISO (PMID:22368283) RGD PMID:22368283 NCBI chr 1:95,639,597...95,645,295
Ensembl chr 1:95,639,592...95,645,290
JBrowse link
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 involved_in ISO (PMID:22368283) RGD PMID:22368283 NCBI chr20:12,741,164...12,763,616
Ensembl chr20:12,741,477...12,763,620
JBrowse link
negative regulation of histone H3-K9 methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca1 BRCA1, DNA repair associated involved_in ISO
IEA
(PMID:20820192)
GO_REF:0000107
(MGI:5009779|PMID:20820192)
RGD
Ensembl
PMID:20820192 GO_REF:0000107 MGI:5009779 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Dnmt1 DNA methyltransferase 1 involved_in ISO
IEA
(PMID:18413740)
GO_REF:0000107
RGD
Ensembl
PMID:18413740 GO_REF:0000107 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta involved_in ISO (PMID:18413740) RGD PMID:18413740 NCBI chr 3:142,130,592...142,169,124
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Kdm1a lysine demethylase 1A involved_in ISO (MGI:4461095|PMID:20123967) RGD PMID:20123967 MGI:4461095 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Kdm3a lysine demethylase 3A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3764891 (MGI:3763001|PMID:17943087)
Ensembl
RGD
PMID:17943087 GO_REF:0000107 MGI:3763001 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073
JBrowse link
G Pax5 paired box 5 acts_upstream_of_or_within ISO (MGI:3050710|PMID:15258579) RGD PMID:15258579 MGI:3050710 NCBI chr 5:58,763,334...58,945,719
Ensembl chr 5:58,765,036...58,944,326
JBrowse link
negative regulation of histone H3-K9 trimethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm4a lysine demethylase 4A acts_upstream_of_or_within ISO (MGI:3629551|PMID:16738407) RGD PMID:16738407 MGI:3629551 NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501
JBrowse link
G Kdm4b lysine demethylase 4B acts_upstream_of_or_within ISO (MGI:3629551|PMID:16738407) RGD PMID:16738407 MGI:3629551 NCBI chr 9:1,158,737...1,237,228
Ensembl chr 9:1,158,752...1,236,543
JBrowse link
G Kdm4c lysine demethylase 4C acts_upstream_of_or_within ISO (MGI:3629551|PMID:16738407) RGD PMID:16738407 MGI:3629551 NCBI chr 5:88,100,710...88,306,821
Ensembl chr 5:88,100,733...88,306,818
JBrowse link
G Kdm4d lysine demethylase 4D acts_upstream_of_or_within ISO (MGI:3629551|PMID:16738407) RGD PMID:16738407 MGI:3629551 NCBI chr 8:11,279,756...11,304,920
Ensembl chr 8:11,268,859...11,305,290
JBrowse link
G Pih1d1 PIH1 domain containing 1 involved_in ISO (PMID:22368283) RGD PMID:22368283 NCBI chr 1:95,639,597...95,645,295
Ensembl chr 1:95,639,592...95,645,290
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:5810254|PMID:25526086) RGD PMID:25526086 MGI:5810254 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 involved_in ISO (PMID:22368283) RGD PMID:22368283 NCBI chr20:12,741,164...12,763,616
Ensembl chr20:12,741,477...12,763,620
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18877
    negative regulation of biological process 5785
      negative regulation of cellular process 5070
        negative regulation of cellular metabolic process 2388
          negative regulation of histone methylation 26
            negative regulation of histone H3-K27 methylation + 5
            negative regulation of histone H3-K36 methylation + 2
            negative regulation of histone H3-K4 methylation + 7
            negative regulation of histone H3-K79 methylation + 1
            negative regulation of histone H3-K9 methylation + 13
            negative regulation of histone H4-K20 methylation 0
Path 2
Term Annotations click to browse term
  biological_process 18877
    metabolic process 11591
      organic substance metabolic process 11152
        macromolecule metabolic process 9583
          protein metabolic process 5863
            protein modification process 3659
              protein alkylation 226
                protein methylation 226
                  histone methylation 181
                    regulation of histone methylation 96
                      negative regulation of histone methylation 26
                        negative regulation of histone H3-K27 methylation + 5
                        negative regulation of histone H3-K36 methylation + 2
                        negative regulation of histone H3-K4 methylation + 7
                        negative regulation of histone H3-K79 methylation + 1
                        negative regulation of histone H3-K9 methylation + 13
                        negative regulation of histone H4-K20 methylation 0
paths to the root