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ONTOLOGY REPORT - ANNOTATIONS

Term:programmed DNA elimination by chromosome breakage
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Accession:GO:0031052 term browser browse the term
Definition:Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage.
Comment:Note that this term refers to breakage of chromosomes during normal DNA well characterized in ciliates but also present in many vertebrates; it is not to be used for DNA damage or other abnormal occurrences.
Synonyms:related_synonym: chromosome breakage


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Path 1
Term Annotations click to browse term
  biological_process 19669
    negative regulation of biological process 6434
      negative regulation of metabolic process 3630
        negative regulation of macromolecule metabolic process 3381
          negative regulation of macromolecule biosynthetic process 2990
            negative regulation of gene expression 1836
              programmed DNA elimination 0
                programmed DNA elimination by chromosome breakage 0
Path 2
Term Annotations click to browse term
  biological_process 19669
    biological regulation 13397
      regulation of biological process 13016
        regulation of metabolic process 7352
          regulation of biosynthetic process 6154
            regulation of cellular biosynthetic process 6061
              regulation of macromolecule biosynthetic process 5960
                regulation of gene expression 5841
                  negative regulation of gene expression 1836
                    programmed DNA elimination 0
                      programmed DNA elimination by chromosome breakage 0
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