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ONTOLOGY REPORT - ANNOTATIONS


Term:programmed DNA elimination
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Accession:GO:0031049 term browser browse the term
Definition:A process in which genomic fragments or entire chromosomes are eliminated from somatic cells or from micronuclei of ciliates. This process occurs in the developing macronucleus (anlage) of a ciliate, as well as in other species, including vertebrates and is an irreversible mechanism of gene silencing.



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programmed DNA elimination by chromosome breakage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmga2 high mobility group AT-hook 2 involved_in ISO (PMID:19549901) RGD PMID:19549901 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
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G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO (MGI:5917601|PMID:28691929) RGD PMID:28691929 MGI:5917601 NCBI chr19:39,235,883...39,268,536
Ensembl chr19:39,236,787...39,268,479
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    cellular process 17431
      cellular component organization or biogenesis 6532
        cellular component organization 6307
          chromatin organization 537
            regulation of gene expression, epigenetic 176
              programmed DNA elimination 2
                programmed DNA elimination by chromosome breakage 2
                programmed DNA elimination by elimination of internal DNA segments 0
Path 2
Term Annotations click to browse term
  biological_process 18734
    cellular process 17431
      cellular component organization or biogenesis 6532
        cellular component organization 6307
          organelle organization 3900
            chromosome organization 969
              chromatin organization 537
                regulation of gene expression, epigenetic 176
                  programmed DNA elimination 2
                    programmed DNA elimination by chromosome breakage 2
                    programmed DNA elimination by elimination of internal DNA segments 0
paths to the root