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ONTOLOGY REPORT - ANNOTATIONS

Term:pancreas development
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Accession:GO:0031016 term browser browse the term
Definition:The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones.
Synonyms:xref: Wikipedia:Pancreas


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pancreas development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR2B activin A receptor type 2B acts_upstream_of_or_within ISO (PMID:17849440) MGI PMID:17849440 NCBI chr 3:38,350,838...38,389,839
Ensembl chr 3:38,633,093...38,662,063 		JBrowse link
G AFP alpha fetoprotein ISO RGD PMID:17880577 RGD:2292043 NCBI chr 4:50,739,197...50,758,459
Ensembl chr 4:56,571,519...56,590,391 		JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15739227)
(PMID:16026781)		 Ensembl
MGI		 PMID:15739227 PMID:16026781 GO_REF:0000107 NCBI chr15:36,925,443...37,038,288
Ensembl chr15:55,237,101...55,557,168 		JBrowse link
G APC APC regulator of WNT signaling pathway ISO RGD PMID:16688812 RGD:4110129 NCBI chr 5:108,070,697...108,208,273
Ensembl chr 5:113,904,352...114,009,709 		JBrowse link
G CCKAR cholecystokinin A receptor ISO RGD PMID:10403848 RGD:2313336 NCBI chr 4:20,881,340...20,890,986
Ensembl chr 4:26,157,702...26,166,773 		JBrowse link
G CTNNB1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16192304) Ensembl
MGI		 PMID:16192304 GO_REF:0000107 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO (PMID:11997520) MGI PMID:11997520 NCBI chr2A:87,688,732...87,759,580
Ensembl chr2A:89,596,833...89,667,468 		JBrowse link
G FGF10 fibroblast growth factor 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15329346) Ensembl
MGI		 PMID:15329346 GO_REF:0000107 NCBI chr 5:65,979,443...66,069,314
Ensembl chr 5:71,028,187...71,111,706 		JBrowse link
G FOXF1 forkhead box F1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:67,183,416...67,188,211
Ensembl chr16:86,516,119...86,519,949 		JBrowse link
G GATA6 GATA binding protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16887115) Ensembl
MGI		 PMID:16887115 GO_REF:0000107 NCBI chr18:15,411,764...15,444,402 JBrowse link
G GDF11 growth differentiation factor 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15548585) Ensembl
MGI		 PMID:15548585 GO_REF:0000107 NCBI chr12:33,154,530...33,168,427
Ensembl chr12:33,879,180...33,893,252 		JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19619492) Ensembl
MGI		 PMID:19619492 GO_REF:0000107 NCBI chr 3:191,432,513...191,435,387
Ensembl chr 3:201,749,044...201,754,257 		JBrowse link
G HHEX hematopoietically expressed homeobox acts_upstream_of_or_within ISO (PMID:16364283) MGI PMID:16364283 NCBI chr10:89,433,402...89,439,137
Ensembl chr10:92,947,373...92,952,992 		JBrowse link
G HNF1A HNF1 homeobox A involved_in IEA InterPro GO_REF:0000002 NCBI chr12:118,562,308...118,584,596
Ensembl chr12:121,932,671...121,955,911 		JBrowse link
G HNF1B HNF1 homeobox B involved_in IEA InterPro GO_REF:0000002 NCBI chr17:19,333,485...19,392,147
Ensembl chr17:19,633,424...19,691,863 		JBrowse link
G IFT88 intraflagellar transport 88 acts_upstream_of_or_within ISO (PMID:11773599) MGI PMID:11773599 NCBI chr13:1,893,102...2,017,771
Ensembl chr13:20,206,471...20,331,204 		JBrowse link
G IHH Indian hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11044404)
(PMID:10821773)		 Ensembl
MGI		 PMID:10821773 PMID:11044404 GO_REF:0000107 NCBI chr2B:106,312,472...106,319,124
Ensembl chr2B:224,906,271...224,911,506 		JBrowse link
G ILDR2 immunoglobulin like domain containing receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18654634) Ensembl
MGI
TreeGrafter		 PMID:18654634 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:142,315,984...142,395,729
Ensembl chr 1:146,125,919...146,181,822 		JBrowse link
G INVS inversin acts_upstream_of_or_within ISO (PMID:9771707) MGI PMID:9771707 NCBI chr 9:71,185,345...71,395,015
Ensembl chr 9:99,329,528...99,508,260 		JBrowse link
G ISL1 ISL LIM homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9000074) Ensembl
MGI		 PMID:9000074 GO_REF:0000107 NCBI chr 5:62,635,095...62,650,141
Ensembl chr 5:64,252,715...64,264,674 		JBrowse link
G MEIS2 Meis homeobox 2 ISO RGD PMID:15660282 RGD:2304272 NCBI chr15:15,814,739...16,025,512
Ensembl chr15:34,072,665...34,282,477 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO RGD PMID:8954115 RGD:2317563 NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159 		JBrowse link
G MNX1 motor neuron and pancreas homeobox 1 acts_upstream_of_or_within ISO (PMID:10471501) MGI PMID:10471501 NCBI chr 7:148,622,701...148,628,532 JBrowse link
G MSLN mesothelin ISO RGD PMID:18505465 RGD:2326046 Ensembl chr16:777,146...783,449 JBrowse link
G MST1R macrophage stimulating 1 receptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:49,818,538...49,835,713
Ensembl chr 3:51,054,795...51,072,401 		JBrowse link
G NKX3-2 NK3 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15329346) Ensembl
MGI		 PMID:15329346 GO_REF:0000107 NCBI chr 4:7,958,218...7,961,844
Ensembl chr 4:13,258,949...13,262,458 		JBrowse link
G ONECUT1 one cut homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17400205) Ensembl
MGI		 PMID:17400205 GO_REF:0000107 NCBI chr15:31,694,830...31,727,644
Ensembl chr15:50,016,010...50,053,062 		JBrowse link
G ONECUT2 one cut homeobox 2 acts_upstream_of_or_within ISO (PMID:17400205) MGI PMID:17400205 NCBI chr18:50,826,110...50,882,127 JBrowse link
G PAX2 paired box 2 involved_in ISO (MGI:48612|PMID:1723950) UniProt PMID:1723950 MGI:48612 NCBI chr10:97,344,978...97,429,086
Ensembl chr10:100,822,676...100,904,028 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 ISO RGD PMID:17221210 RGD:2308896 NCBI chr 5:18,917,488...18,960,102
Ensembl chr 5:19,064,004...19,106,486 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO (PMID:8625829)
(PMID:16418487)		 RGD
MGI		 PMID:8625829 PMID:16418487 PMID:18778483 RGD:2311165 NCBI chr13:9,199,572...9,206,202 JBrowse link
G PROX1 prospero homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:189,556,124...189,609,297
Ensembl chr 1:194,412,980...194,460,763 		JBrowse link
G PTF1A pancreas associated transcription factor 1a involved_in
acts_upstream_of_or_within		 ISO (PMID:15543146)
(PMID:17938243)		 UniProt
MGI		 PMID:15543146 PMID:17938243 NCBI chr10:23,356,165...23,359,579 JBrowse link
G RBM4 RNA binding motif protein 4 acts_upstream_of_or_within ISO (PMID:23129807) MGI PMID:23129807 NCBI chr11:61,996,221...62,026,007
Ensembl chr11:65,298,404...65,349,183 		JBrowse link
G SELENOT selenoprotein T involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23913443) Ensembl
MGI		 PMID:23913443 GO_REF:0000107 NCBI chr 3:147,620,862...147,648,039
Ensembl chr 3:155,194,428...155,221,578 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10821773), (PMID:11044404)
(PMID:11044404)		 Ensembl
MGI		 PMID:10821773 PMID:11044404 GO_REF:0000107 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651 		JBrowse link
G SMAD2 SMAD family member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17849440) Ensembl
MGI		 PMID:17849440 GO_REF:0000107 NCBI chr18:41,213,001...41,309,902
Ensembl chr18:44,580,905...44,668,530 		JBrowse link
G TGFB2 transforming growth factor beta 2 ISO RGD PMID:16479313 RGD:2302093 NCBI chr 1:193,907,398...194,005,800
Ensembl chr 1:198,758,751...198,859,041 		JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein ISO RGD PMID:19916172 RGD:8694406 Ensembl chr 4:6,345,864...6,379,287 JBrowse link
G ZNF808 zinc finger protein 808 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:49,481,054...49,522,318
Ensembl chr19:58,412,939...58,426,454 		JBrowse link
branching involved in pancreas morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PROX1 prospero homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22178591) Ensembl
MGI		 PMID:22178591 GO_REF:0000107 NCBI chr 1:189,556,124...189,609,297
Ensembl chr 1:194,412,980...194,460,763 		JBrowse link
determination of pancreatic left/right asymmetry term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCDC39 coiled-coil domain 39 molecular ruler complex subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:177,640,127...177,705,885
Ensembl chr 3:185,813,245...185,878,362 		JBrowse link
G CCDC40 coiled-coil domain 40 molecular ruler complex subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:74,120,483...74,187,323
Ensembl chr17:79,656,287...79,722,565 		JBrowse link
G DNAAF1 dynein axonemal assembly factor 1 involved_in ISO (PMID:19944405) BHF-UCL PMID:19944405 NCBI chr16:64,810,498...64,843,705
Ensembl chr16:84,154,130...84,184,914 		JBrowse link
G NPHP3 nephrocystin 3 involved_in ISO (PMID:20007846) BHF-UCL PMID:20007846 NCBI chr 3:129,753,399...129,795,300 JBrowse link
G ZIC3 Zic family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:126,691,534...126,705,788
Ensembl chr  X:136,954,024...136,967,819 		JBrowse link
endocrine pancreas development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:7527053 GO_REF:0000118 RGD:2306957 NCBI chr 9:51,647,404...51,665,990
Ensembl chr 9:71,929,728...71,948,779 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 ISO RGD PMID:11000281 RGD:2315710 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211 		JBrowse link
G CLU clusterin ISO RGD PMID:16411126 RGD:1582421 NCBI chr 8:26,867,973...26,884,838
Ensembl chr 8:24,070,053...24,083,523 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:87,688,732...87,759,580
Ensembl chr2A:89,596,833...89,667,468 		JBrowse link
G FOXA2 forkhead box A2 involved_in
acts_upstream_of_or_within		 ISO (PMID:12124776)
(PMID:15680365)		 BHF-UCL
MGI		 PMID:12124776 PMID:15680365 NCBI chr20:22,519,942...22,524,262 JBrowse link
G GIP gastric inhibitory polypeptide acts_upstream_of_or_within ISO (PMID:21270265) MGI PMID:21270265 NCBI chr17:8,573,104...8,580,424 JBrowse link
G GIPR gastric inhibitory polypeptide receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21270265) Ensembl
MGI		 PMID:21270265 GO_REF:0000107 NCBI chr19:42,673,553...42,688,059
Ensembl chr19:51,213,090...51,225,293 		JBrowse link
G HNF1B HNF1 homeobox B involved_in ISO (PMID:16801329) UniProt PMID:16801329 NCBI chr17:19,333,485...19,392,147
Ensembl chr17:19,633,424...19,691,863 		JBrowse link
G IL6 interleukin 6 involved_in ISO (MGI:3807360|PMID:18719127) BHF-UCL PMID:18719127 MGI:3807360 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G IL6R interleukin 6 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:129,761,914...129,824,386
Ensembl chr 1:133,374,078...133,433,089 		JBrowse link
G INSM1 INSM transcriptional repressor 1 acts_upstream_of_or_within ISO (PMID:16511571) MGI PMID:16511571 NCBI chr20:20,317,060...20,320,051 JBrowse link
G MNX1 motor neuron and pancreas homeobox 1 acts_upstream_of_or_within ISO (PMID:10471501) MGI PMID:10471501 NCBI chr 7:148,622,701...148,628,532 JBrowse link
G MYT1 myelin transcription factor 1 acts_upstream_of_or_within ISO (PMID:17928203) MGI PMID:17928203 Ensembl chr20:62,108,924...62,151,936 JBrowse link
G NEUROD1 neuronal differentiation 1 involved_in ISO (MGI:1096974|PMID:9308961), (MGI:1352314|PMID:10639171) BHF-UCL PMID:9308961 PMID:10639171 MGI:1096974 MGI:1352314 NCBI chr2B:68,939,341...68,943,516 JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9584121) Ensembl
MGI		 PMID:9584121 GO_REF:0000107 NCBI chr20:21,468,872...21,480,627
Ensembl chr20:21,429,401...21,432,492 		JBrowse link
G NKX6-1 NK6 homeobox 1 acts_upstream_of_or_within ISO (PMID:15944193) MGI PMID:15944193 NCBI chr 4:39,683,420...39,689,651 JBrowse link
G NKX6-2 NK6 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15944193) Ensembl
MGI		 PMID:15944193 GO_REF:0000107 Ensembl chr10:133,682,456...133,683,445 JBrowse link
G ONECUT1 one cut homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17400205) Ensembl
MGI		 PMID:17400205 GO_REF:0000107 NCBI chr15:31,694,830...31,727,644
Ensembl chr15:50,016,010...50,053,062 		JBrowse link
G ONECUT2 one cut homeobox 2 acts_upstream_of_or_within ISO (PMID:17400205) MGI PMID:17400205 NCBI chr18:50,826,110...50,882,127 JBrowse link
G PDE3B phosphodiesterase 3B acts_upstream_of_or_within ISO (PMID:14736883) MGI PMID:14736883 NCBI chr11:14,746,301...14,961,316
Ensembl chr11:14,437,060...14,648,616 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO (PMID:18155690) MGI PMID:18155690 NCBI chr13:9,199,572...9,206,202 JBrowse link
G RFX3 regulatory factor X3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:3,024,016...3,332,266
Ensembl chr 9:3,223,405...3,398,839 		JBrowse link
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:114,686,132...114,741,072
Ensembl chr 6:118,828,973...118,883,884 		JBrowse link
G SOX4 SRY-box transcription factor 4 acts_upstream_of_or_within ISO (PMID:16306355) MGI PMID:16306355 NCBI chr 6:21,422,846...21,427,779 JBrowse link
G SOX9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (PMID:18723011) MGI PMID:18723011 NCBI chr17:66,028,737...66,034,122 JBrowse link
G ZNF800 zinc finger protein 800 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:33653874) Ensembl
MGI		 PMID:33653874 GO_REF:0000107 NCBI chr 7:119,337,671...119,584,646
Ensembl chr 7:132,023,845...132,042,024 		JBrowse link
exocrine pancreas development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CELA1 chymotrypsin like elastase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17222338) Ensembl
MGI		 PMID:17222338 GO_REF:0000107 NCBI chr12:37,407,189...37,425,684
Ensembl chr12:38,292,562...38,310,197 		JBrowse link
G IGF1 insulin like growth factor 1 acts_upstream_of_or_within ISO (PMID:12101187) MGI PMID:12101187 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177 		JBrowse link
G IGF1R insulin like growth factor 1 receptor acts_upstream_of_or_within ISO (PMID:12101187) MGI PMID:12101187 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974 		JBrowse link
G IGF2 insulin like growth factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12101187) Ensembl
MGI		 PMID:12101187 GO_REF:0000107 NCBI chr11:2,170,190...2,199,442
Ensembl chr11:2,202,743...2,228,890 		JBrowse link
G INSR insulin receptor acts_upstream_of_or_within ISO (PMID:12101187) MGI PMID:12101187 NCBI chr19:6,393,407...6,578,234
Ensembl chr19:7,260,246...7,414,889 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO (PMID:16126192) MGI PMID:16126192 NCBI chr13:9,199,572...9,206,202 JBrowse link
G PTF1A pancreas associated transcription factor 1a involved_in ISO PMID:10768861 UniProt PMID:10768861 RGD:8554373 NCBI chr10:23,356,165...23,359,579 JBrowse link
G WLS Wnt ligand secretion mediator involved_in ISO (MGI:4834980|PMID:20614471) ParkinsonsUK-UCL PMID:20614471 MGI:4834980 NCBI chr 1:67,336,009...67,470,265
Ensembl chr 1:69,318,742...69,425,652 		JBrowse link
G XBP1 X-box binding protein 1 acts_upstream_of_or_within ISO (PMID:16362047) MGI PMID:16362047 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943 		JBrowse link
negative regulation of pancreatic A cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10615124) Ensembl
MGI		 PMID:10615124 GO_REF:0000107 NCBI chr 3:191,432,513...191,435,387
Ensembl chr 3:201,749,044...201,754,257 		JBrowse link
negative regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFTR CF transmembrane conductance regulator ISO RGD PMID:23178930 RGD:11567224 NCBI chr 7:109,449,847...109,633,023
Ensembl chr 7:122,129,798...122,327,864 		JBrowse link
pancreas morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CELA1 chymotrypsin like elastase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17222338) Ensembl
MGI		 PMID:17222338 GO_REF:0000107 NCBI chr12:37,407,189...37,425,684
Ensembl chr12:38,292,562...38,310,197 		JBrowse link
G NR5A2 nuclear receptor subfamily 5 group A member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25063451) Ensembl
MGI		 PMID:25063451 GO_REF:0000107 NCBI chr 1:175,625,140...175,775,955
Ensembl chr 1:179,934,573...180,083,607 		JBrowse link
G SMO smoothened, frizzled class receptor acts_upstream_of_or_within ISO (PMID:20185815) MGI PMID:20185815 NCBI chr 7:121,143,968...121,168,873
Ensembl chr 7:133,668,304...133,693,048 		JBrowse link
pancreatic A cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX6 paired box 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:31,753,190...31,782,225
Ensembl chr11:31,641,813...31,664,474 		JBrowse link
pancreatic A cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA6 GATA binding protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16887115) Ensembl
MGI		 PMID:16887115 GO_REF:0000107 NCBI chr18:15,411,764...15,444,402 JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:10615124) Ensembl
MGI		 PMID:10615124 GO_REF:0000107 NCBI chr 3:191,432,513...191,435,387
Ensembl chr 3:201,749,044...201,754,257 		JBrowse link
G INSM1 INSM transcriptional repressor 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:3619850|PMID:16511571)
(PMID:16511571)		 UniProt
MGI		 PMID:16511571 MGI:3619850 NCBI chr20:20,317,060...20,320,051 JBrowse link
G NKX6-1 NK6 homeobox 1 acts_upstream_of_or_within ISO (PMID:15944193) MGI PMID:15944193 NCBI chr 4:39,683,420...39,689,651 JBrowse link
G NKX6-2 NK6 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15944193) Ensembl
MGI		 PMID:15944193 GO_REF:0000107 Ensembl chr10:133,682,456...133,683,445 JBrowse link
G ONECUT1 one cut homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10825208) Ensembl
MGI		 PMID:10825208 GO_REF:0000107 NCBI chr15:31,694,830...31,727,644
Ensembl chr15:50,016,010...50,053,062 		JBrowse link
G PAX6 paired box 6 ISO RGD PMID:20592023 RGD:8552352 NCBI chr11:31,753,190...31,782,225
Ensembl chr11:31,641,813...31,664,474 		JBrowse link
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:114,686,132...114,741,072
Ensembl chr 6:118,828,973...118,883,884 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25186293) Ensembl
MGI		 PMID:25186293 GO_REF:0000107 NCBI chr 3:10,077,630...10,089,499
Ensembl chr 3:10,430,143...10,440,234 		JBrowse link
pancreatic A cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NEUROD1 neuronal differentiation 1 acts_upstream_of_or_within ISO (PMID:17988662) MGI PMID:17988662 NCBI chr2B:68,939,341...68,943,516 JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17202186)
(PMID:17988662)		 Ensembl
MGI		 PMID:17202186 PMID:17988662 GO_REF:0000107 NCBI chr20:21,468,872...21,480,627
Ensembl chr20:21,429,401...21,432,492 		JBrowse link
pancreatic D cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ONECUT1 one cut homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10825208) Ensembl
MGI		 PMID:10825208 GO_REF:0000107 NCBI chr15:31,694,830...31,727,644
Ensembl chr15:50,016,010...50,053,062 		JBrowse link
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:114,686,132...114,741,072
Ensembl chr 6:118,828,973...118,883,884 		JBrowse link
pancreatic epsilon cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:114,686,132...114,741,072
Ensembl chr 6:118,828,973...118,883,884 		JBrowse link
pancreatic PP cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NEUROD1 neuronal differentiation 1 acts_upstream_of_or_within ISO (PMID:17988662) MGI PMID:17988662 NCBI chr2B:68,939,341...68,943,516 JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17988662) Ensembl
MGI		 PMID:17988662 GO_REF:0000107 NCBI chr20:21,468,872...21,480,627
Ensembl chr20:21,429,401...21,432,492 		JBrowse link
positive regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAD BCL2 associated agonist of cell death involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257 		JBrowse link
G RFX3 regulatory factor X3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:3,024,016...3,332,266
Ensembl chr 9:3,223,405...3,398,839 		JBrowse link
regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMAL1 basic helix-loop-helix ARNT like 1 involved_in ISO (MGI:4819446|PMID:20562852) UniProt PMID:20562852 MGI:4819446 NCBI chr11:13,436,580...13,547,135
Ensembl chr11:13,163,028...13,240,376 		JBrowse link
G CLOCK clock circadian regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:68,391,310...68,509,813
Ensembl chr 4:75,018,898...75,066,726 		JBrowse link
G RHEB Ras homolog, mTORC1 binding involved_in ISO (PMID:19258434) CACAO PMID:19258434 NCBI chr 7:143,054,747...143,108,011 JBrowse link
type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:55,302,721...55,425,248
Ensembl chr 6:56,936,850...57,059,519 		JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649 		JBrowse link
G CDH2 cadherin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:21,210,001...21,435,919
Ensembl chr18:24,812,019...25,008,325 		JBrowse link
G CDK6 cyclin dependent kinase 6 involved_in ISO (PMID:20668294) UniProt PMID:20668294 NCBI chr 7:84,603,419...84,835,082 JBrowse link
G DLL1 delta like canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759 		JBrowse link
G INSM1 INSM transcriptional repressor 1 acts_upstream_of_or_within ISO (PMID:16951258) MGI PMID:16951258 NCBI chr20:20,317,060...20,320,051 JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17456846)
(PMID:17202186)		 Ensembl
MGI		 PMID:17202186 PMID:17456846 GO_REF:0000107 NCBI chr20:21,468,872...21,480,627
Ensembl chr20:21,429,401...21,432,492 		JBrowse link
G NKX6-1 NK6 homeobox 1 ISO RGD PMID:9603781 RGD:2326025 NCBI chr 4:39,683,420...39,689,651 JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (MGI:4365695|PMID:19635472) UniProt PMID:19635472 MGI:4365695 NCBI chr16:1,394,447...1,463,735 JBrowse link
G SIDT2 SID1 transmembrane family member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23776622) Ensembl
MGI		 PMID:23776622 GO_REF:0000107 NCBI chr11:112,012,734...112,031,403
Ensembl chr11:115,946,725...115,963,408 		JBrowse link
G SMO smoothened, frizzled class receptor acts_upstream_of_or_within ISO (PMID:20185815) MGI PMID:20185815 NCBI chr 7:121,143,968...121,168,873
Ensembl chr 7:133,668,304...133,693,048 		JBrowse link
G WNT5A Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16246260) Ensembl
MGI		 PMID:16246260 GO_REF:0000107 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051 		JBrowse link
type B pancreatic cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA6 GATA binding protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16887115) Ensembl
MGI		 PMID:16887115 GO_REF:0000107 NCBI chr18:15,411,764...15,444,402 JBrowse link
G INSM1 INSM transcriptional repressor 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:3619850|PMID:16511571)
(PMID:16511571)		 UniProt
MGI		 PMID:16511571 MGI:3619850 NCBI chr20:20,317,060...20,320,051 JBrowse link
G MEN1 menin 1 ISO RGD PMID:24157940 RGD:9589069 NCBI chr11:60,159,009...60,166,222
Ensembl chr11:63,499,962...63,507,164 		JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:14729487) Ensembl
MGI		 PMID:14729487 GO_REF:0000107 NCBI chr20:21,468,872...21,480,627
Ensembl chr20:21,429,401...21,432,492 		JBrowse link
G NKX6-1 NK6 homeobox 1 acts_upstream_of_or_within ISO (PMID:15944193) MGI PMID:15944193 NCBI chr 4:39,683,420...39,689,651 JBrowse link
G ONECUT1 one cut homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10825208) Ensembl
MGI		 PMID:10825208 GO_REF:0000107 NCBI chr15:31,694,830...31,727,644
Ensembl chr15:50,016,010...50,053,062 		JBrowse link
G PAX4 paired box 4 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:14729487) Ensembl
MGI		 PMID:14729487 GO_REF:0000107 NCBI chr 7:119,605,924...119,613,579
Ensembl chr 7:132,260,859...132,268,516 		JBrowse link
G PAX6 paired box 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:22764048) RGD
MGI
Ensembl		 PMID:22403172 PMID:22764048 GO_REF:0000107 RGD:8552355 NCBI chr11:31,753,190...31,782,225
Ensembl chr11:31,641,813...31,664,474 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16418487) TreeGrafter
MGI		 PMID:16418487 GO_REF:0000118 NCBI chr13:9,199,572...9,206,202 JBrowse link
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:114,686,132...114,741,072
Ensembl chr 6:118,828,973...118,883,884 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25186293) Ensembl
MGI		 PMID:25186293 GO_REF:0000107 NCBI chr 3:10,077,630...10,089,499
Ensembl chr 3:10,430,143...10,440,234 		JBrowse link
type B pancreatic cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17202186), (PMID:17988662) Ensembl
MGI		 PMID:17202186 PMID:17988662 GO_REF:0000107 NCBI chr20:21,468,872...21,480,627
Ensembl chr20:21,429,401...21,432,492 		JBrowse link
type B pancreatic cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHLHA15 basic helix-loop-helix family member a15 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16423820) Ensembl
MGI		 PMID:16423820 GO_REF:0000107 NCBI chr 7:6,306,929...6,311,026
Ensembl chr 7:103,677,022...103,677,593 		JBrowse link
G GDF11 growth differentiation factor 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15548585) Ensembl
MGI		 PMID:15548585 GO_REF:0000107 NCBI chr12:33,154,530...33,168,427
Ensembl chr12:33,879,180...33,893,252 		JBrowse link
G RFX3 regulatory factor X3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:3,024,016...3,332,266
Ensembl chr 9:3,223,405...3,398,839 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    developmental process 6563
      anatomical structure development 6172
        animal organ development 3469
          pancreas development 93
            determination of pancreatic left/right asymmetry 5
            endocrine pancreas development + 49
            exocrine pancreas development 9
            pancreas morphogenesis + 4
paths to the root