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ONTOLOGY REPORT - ANNOTATIONS


Term:thiamine pyrophosphate binding
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Accession:GO:0030976 term browser browse the term
Definition:Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
Synonyms:exact_synonym: TPP binding;   aneurine pyrophosphate binding;   cocarboxylase binding;   diphosphothiamin binding;   thiamin pyrophosphate binding


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thiamine pyrophosphate binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC141220.4 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr17:76,306,649...76,374,507 JBrowse link
G Dhtkd1 dehydrogenase E1 and transketolase domain containing 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:76,306,585...76,358,058
Ensembl chr17:76,306,585...76,358,058
JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 enables IDA
IBA
ISO
PMID:10468558
PMID:21873635
(PMID:10468558), (PMID:21708296)
RGD PMID:10468558 PMID:21708296, PMID:10468558, PMID:21873635 RGD:708588, RGD:13792537 NCBI chr16:7,720,047...7,758,119
Ensembl chr16:7,714,465...7,758,189
JBrowse link
G Ilvbl ilvB acetolactate synthase like enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:14,044,586...14,054,639
Ensembl chr 7:14,044,586...14,054,639
JBrowse link
G LOC108348261 transketolase-like protein 1 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr  X:156,507,797...156,540,733 JBrowse link
G Ogdh oxoglutarate dehydrogenase enables ISO
ISS
(PMID:24495017)
GO_REF:0000024
RGD
UniProt
PMID:24495017 GO_REF:0000024 NCBI chr14:86,414,924...86,481,903
Ensembl chr14:86,414,949...86,613,327
JBrowse link
G Ogdhl oxoglutarate dehydrogenase L enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:8,497,495...8,523,552
Ensembl chr16:8,497,569...8,523,557
JBrowse link
G Tkt transketolase enables IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:16116031, PMID:21873635 RGD:1580394, RGD:13792537 NCBI chr16:6,609,670...6,634,608
Ensembl chr16:6,609,668...6,634,595
JBrowse link
G Tktl1 transketolase-like 1 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:156,507,797...156,540,733
Ensembl chr  X:156,507,797...156,540,733
JBrowse link
G Tktl2 transketolase-like 2 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:24,944,197...24,951,478
Ensembl chr16:24,949,425...24,951,612
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20083
    binding 17057
      heterocyclic compound binding 5675
        thiamine pyrophosphate binding 10
Path 2
Term Annotations click to browse term
  molecular_function 20083
    binding 17057
      small molecule binding 2525
        vitamin binding 142
          thiamine pyrophosphate binding 10
paths to the root