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ONTOLOGY REPORT - ANNOTATIONS


Term:thiamine pyrophosphate binding
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Accession:GO:0030976 term browser browse the term
Definition:Binding to thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
Synonyms:exact_synonym: TPP binding;   aneurine pyrophosphate binding;   cocarboxylase binding;   diphosphothiamin binding;   thiamin pyrophosphate binding



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thiamine pyrophosphate binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhtkd1 dehydrogenase E1 and transketolase domain containing 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:72,355,201...72,406,725
Ensembl chr17:72,355,201...72,406,723
JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 enables IDA
IBA
ISO
PMID:10468558
PMID:21873635
(PMID:10468558), (PMID:21708296)
RGD PMID:10468558 PMID:21708296 PMID:10468558 PMID:21873635 RGD:708588, RGD:13792537 NCBI chr16:6,826,881...6,863,027
Ensembl chr16:6,824,906...6,863,027
JBrowse link
G Ilvbl ilvB acetolactate synthase like enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:11,039,870...11,049,924
Ensembl chr 7:11,039,871...11,049,924
JBrowse link
G Ogdh oxoglutarate dehydrogenase enables ISO
ISS
(PMID:24495017)
GO_REF:0000024
RGD
UniProt
PMID:24495017 GO_REF:0000024 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
JBrowse link
G Ogdhl oxoglutarate dehydrogenase L enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:7,578,305...7,604,385
Ensembl chr16:7,578,367...7,604,386
JBrowse link
G Tkt transketolase enables IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:16116031 PMID:21873635 RGD:1580394, RGD:13792537 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
JBrowse link
G Tktl1 transketolase-like 1 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:151,954,261...151,987,208
Ensembl chr  X:151,954,175...151,987,208
JBrowse link
G Tktl2 transketolase-like 2 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:23,202,460...23,209,741
Ensembl chr16:23,202,453...23,209,742
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19436
    binding 16663
      quaternary ammonium group binding 44
        thiamine pyrophosphate binding 8
Path 2
Term Annotations click to browse term
  molecular_function 19436
    binding 16663
      ion binding 5060
        cation binding 3387
          thiamine pyrophosphate binding 8
paths to the root