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ONTOLOGY REPORT - ANNOTATIONS

Term:retromer, cargo-selective complex
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Accession:GO:0030906 term browser browse the term
Definition:The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals.
Synonyms:exact_synonym: cargo-selective retromer subcomplex;   retromer CSC;   retromer complex, inner shell;   retromer, CRC;   retromer, cargo recognition complex


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retromer, cargo-selective complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vps26a VPS26 retromer complex component A part_of ISO
IEA		 (PMID:27385586)
GO_REF:0000107		 RGD
Ensembl		 PMID:27385586 GO_REF:0000107 NCBI chr20:30,404,320...30,434,266
Ensembl chr20:30,404,325...30,434,131 		JBrowse link
G Vps29 VPS29 retromer complex component part_of ISO
IEA		 (PMID:27385586)
GO_REF:0000107		 RGD
Ensembl		 PMID:27385586 GO_REF:0000107 NCBI chr12:34,208,911...34,217,977
Ensembl chr12:34,207,263...34,217,964 		JBrowse link
G Vps35 VPS35 retromer complex component part_of ISO (PMID:20164305), (PMID:27385586) RGD PMID:20164305 PMID:27385586 NCBI chr19:21,765,771...21,801,620
Ensembl chr19:21,765,749...21,801,618 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21392
    protein-containing complex 6987
      membrane protein complex 1451
        retromer, cargo-selective complex 3
Path 2
Term Annotations click to browse term
  cellular_component 21392
    cellular anatomical entity 21234
      membrane 10503
        membrane protein complex 1451
          retromer complex 22
            retromer, cargo-selective complex 3
paths to the root