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ONTOLOGY REPORT - ANNOTATIONS


Term:retromer, tubulation complex
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Accession:GO:0030905 term browser browse the term
Definition:The dimeric subcomplex of the retromer, believed to be peripherally associated with the membrane. This dimeric complex is responsible for remodelling endosomal membranes to form a tube-structure to which cargo molecules are selected for recycling. The budding yeast complex comprises Vps5p and Vps17p, and may contain multiple copies of a Vps5p/Vps17p dimer. The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6.
Synonyms:exact_synonym: SNX-BAR dimer;   heterodimeric membrane-deforming retromer subcomplex;   retromer complex, outer shell



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retromer, tubulation complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snx1 sorting nexin 1 part_of ISO UniProtKB:O60749 (PMID:11102511) RGD PMID:11102511 NCBI chr 8:66,630,086...66,670,418
Ensembl chr 8:66,630,086...66,670,360
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G Snx2 sorting nexin 2 part_of ISO UniProtKB:Q13596 (PMID:11102511) RGD PMID:11102511 NCBI chr18:46,602,223...46,643,870
Ensembl chr18:46,602,284...46,643,865
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Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19896
    protein-containing complex 5946
      membrane protein complex 1234
        retromer, tubulation complex 2
Path 2
Term Annotations click to browse term
  cellular_component 19896
    cellular anatomical entity 19599
      membrane 9895
        membrane protein complex 1234
          retromer complex 21
            retromer, tubulation complex 2
paths to the root