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ONTOLOGY REPORT - ANNOTATIONS


Term:thyroid gland development
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Accession:GO:0030878 term browser browse the term
Definition:The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone.



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thyroid gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO MGI:97847 (MGI:3832113|PMID:18952847) RGD PMID:18952847 MGI:3832113 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide acts_upstream_of_or_within ISO MGI:1857152 (MGI:1316794|PMID:12114718) RGD PMID:12114718 MGI:1316794 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
JBrowse link
G Duox2 dual oxidase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3712359 (MGI:3712355|PMID:17440044)
Ensembl
RGD
PMID:17440044 GO_REF:0000107 MGI:3712355 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902
JBrowse link
G Edn1 endothelin 1 involved_in ISO MGI:1857637 (MGI:5749301|PMID:26506449) RGD PMID:26506449 MGI:5749301 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A involved_in ISO
IEA
MGI:4867385 (MGI:5749301|PMID:26506449)
GO_REF:0000107
RGD
Ensembl
PMID:26506449 GO_REF:0000107 MGI:5749301 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (MGI:3688470|PMID:11062007) RGD PMID:11062007 MGI:3688470 NCBI chr 2:50,801,897...50,875,428
Ensembl chr 2:50,800,992...50,876,866
JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO MGI:2150347|MGI:3757964|MGI:98493 (MGI:3848569|PMID:19389367) RGD PMID:19389367 MGI:3848569 NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359
JBrowse link
G Foxe1 forkhead box E1 involved_in
acts_upstream_of_or_within
ISO (PMID:15494458), (PMID:9697705)
MGI:2181780 (MGI:1276273|PMID:9697704)
RGD PMID:9697704 PMID:9697705 PMID:15494458 MGI:1276273 NCBI chr 5:60,630,027...60,632,835
Ensembl chr 5:60,630,027...60,632,835
JBrowse link
G Hesx1 HESX homeobox 1 acts_upstream_of_or_within ISO MGI:102764 (MGI:3821506|PMID:18775421) RGD PMID:18775421 MGI:3821506 NCBI chr16:2,191,852...2,193,957
Ensembl chr16:2,191,852...2,193,957
JBrowse link
G Hhex hematopoietically expressed homeobox acts_upstream_of_or_within ISO MGI:2177762 (MGI:1855906|PMID:10804184), (MGI:3522522|PMID:15581879) RGD PMID:10804184 PMID:15581879 MGI:1855906 MGI:3522522 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042
JBrowse link
G Hoxa3 homeobox A3 acts_upstream_of_or_within ISO MGI:1857992|MGI:96184|MGI:96207 (MGI:1197395|PMID:9524238), (MGI:1201272|PMID:9520319), (MGI:74186|PMID:7635047) RGD PMID:7635047 PMID:9520319 PMID:9524238 MGI:1197395 MGI:1201272 MGI:74186 NCBI chr 4:81,269,243...81,313,218
Ensembl chr 4:81,269,243...81,313,218
JBrowse link
G Hoxa5 homeo box A5 acts_upstream_of_or_within ISO MGI:2150397 (MGI:2667733|PMID:12815622) RGD PMID:12815622 MGI:2667733 NCBI chr 4:81,302,341...81,306,234
Ensembl chr 4:81,302,353...81,306,234
JBrowse link
G Hoxb3 homeo box B3 acts_upstream_of_or_within ISO MGI:96175 (MGI:1201272|PMID:9520319) RGD PMID:9520319 MGI:1201272 NCBI chr10:81,258,739...81,314,134
Ensembl chr10:81,299,357...81,313,107
JBrowse link
G Hoxd3 homeo box D3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:96175 (MGI:1201272|PMID:9520319)
Ensembl
RGD
PMID:9520319 GO_REF:0000107 MGI:1201272 NCBI chr 3:59,638,708...59,650,282
Ensembl chr 3:59,638,708...59,650,282
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1346867 (MGI:3832113|PMID:18952847)
Ensembl
RGD
PMID:18952847 GO_REF:0000107 MGI:3832113 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 acts_upstream_of_or_within ISO MGI:1346866 (MGI:3832113|PMID:18952847) RGD PMID:18952847 MGI:3832113 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Mapk1 mitogen activated protein kinase 1 acts_upstream_of_or_within ISO MGI:1346859 (MGI:3832113|PMID:18952847) RGD PMID:18952847 MGI:3832113 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 acts_upstream_of_or_within ISO MGI:1346858 (MGI:3832113|PMID:18952847) RGD PMID:18952847 MGI:3832113 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:11854319), (PMID:15494458)
MGI:1857494|MGI:3653644|MGI:3653645|MGI:97492 (MGI:3522522|PMID:15581879), (MGI:3652637|PMID:16601074), (MGI:3769976|PMID:16150900)
GO_REF:0000107
RGD
Ensembl
PMID:11854319 PMID:15494458 PMID:15581879 PMID:16150900 PMID:16601074 GO_REF:0000107 MGI:3522522 MGI:3652637 MGI:3769976 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791
JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in IEA
ISO
GO_REF:0000107
(MGI:3828401|PMID:16418214)
(PMID:16418214)
Ensembl
RGD
PMID:16418214 GO_REF:0000107 MGI:3828401 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934
JBrowse link
G Pax8 paired box 8 involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:1337742), (PMID:15494458), (PMID:9590296)
MGI:2156985|MGI:98742 (MGI:1203285|PMID:9590297), (MGI:2156109|PMID:11773436), (PMID:1723950)
GO_REF:0000024
RGD
UniProt
PMID:1337742 PMID:1723950 PMID:9590296 PMID:9590297 PMID:11773436 More... GO_REF:0000024 MGI:1203285 MGI:2156109 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO MGI:88190 (MGI:3832113|PMID:18952847) RGD PMID:18952847 MGI:3832113 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1861186 (MGI:3702792|PMID:16968815)
Ensembl
RGD
PMID:16968815 GO_REF:0000107 MGI:3702792 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Six1 SIX homeobox 1 acts_upstream_of_or_within ISO MGI:2655195 (MGI:3624596|PMID:16530750) RGD PMID:16530750 MGI:3624596 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975
JBrowse link
G Six3 SIX homeobox 3 acts_upstream_of_or_within ISO MGI:96071 (MGI:3821506|PMID:18775421) RGD PMID:18775421 MGI:3821506 NCBI chr 6:9,040,123...9,043,336
Ensembl chr 6:9,036,434...9,053,301
JBrowse link
G Smad3 SMAD family member 3 acts_upstream_of_or_within ISO MGI:108051 (MGI:3618021|PMID:15183723) RGD PMID:15183723 MGI:3618021 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:3522206 (MGI:3832113|PMID:18952847) RGD PMID:18952847 MGI:3832113 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733
JBrowse link
G Tbx1 T-box transcription factor 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:2179136|MGI:2179191|MGI:99604 (MGI:3050165|PMID:15190012), (MGI:3697808|PMID:17164259), (MGI:3848569|PMID:19389367)
UniProt
RGD
PMID:15190012 PMID:17164259 PMID:19389367 GO_REF:0000024 MGI:3050165 MGI:3697808 MGI:3848569 NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380
JBrowse link
G Tg thyroglobulin involved_in ISO
IEA
(PMID:15494458)
GO_REF:0000107
RGD
Ensembl
PMID:15494458 GO_REF:0000107 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
JBrowse link
G Tgfb2 transforming growth factor, beta 2 IEP RGD PMID:18554691 RGD:2302084 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Thra thyroid hormone receptor alpha involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:97492 (MGI:2156109|PMID:11773436)
Ensembl
RGD
PMID:11773436 GO_REF:0000107 MGI:2156109 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
negative regulation of thyroid gland epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir1 microRNA 1 IDA RGD PMID:21816899 RGD:10059418 NCBI chr18:1,887,537...1,887,623 JBrowse link
G Mir28 microRNA 28 IDA RGD PMID:21816899 RGD:10059418 NCBI chr11:75,975,523...75,975,608
Ensembl chr11:75,975,523...75,975,608
JBrowse link
G Mir290 microRNA 290 IDA RGD PMID:21816899 RGD:10059418 NCBI chr 1:65,964,648...65,964,728
Ensembl chr 1:65,964,648...65,964,728
JBrowse link
G Mir296 microRNA 296 IDA RGD PMID:21816899 RGD:10059418 NCBI chr 3:163,051,838...163,051,915
Ensembl chr 3:163,051,838...163,051,915
JBrowse link
G Mir297 microRNA 297 IDA RGD PMID:21816899 RGD:10059418 NCBI chr10:98,216,479...98,216,544 JBrowse link
G Rap1gap Rap1 GTPase-activating protein IMP RGD PMID:17646383 RGD:9835038 NCBI chr 5:149,873,987...149,939,254
Ensembl chr 5:149,892,019...149,939,253
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19512
    developmental process 6931
      anatomical structure development 6346
        animal organ development 4174
          gland development 665
            thyroid gland development 37
              thyroid gland epithelial cell proliferation + 6
Path 2
Term Annotations click to browse term
  biological_process 19512
    developmental process 6931
      anatomical structure development 6346
        multicellular organism development 5773
          system development 5413
            animal organ development 4174
              gland development 665
                thyroid gland development 37
                  thyroid gland epithelial cell proliferation + 6
paths to the root